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July highlights: Mother’s intuition, music therapy & more

Catch up on what you may have missed on Thriving last month. Our staff takes a look back at a few of this month’s favorite posts. A mother’s intuition—and a fall down the stairs—save a little girl’s life Liz Beaulieu is likely the only person in the world who can say she saved her child by falling down the stairs. Her daughter, Arielle, was just 4 days old. Liz was carrying her downstairs when she slipped. Not sure whether Arielle had hit her head, she whisked her to her local ER. “She seemed fine, and they said that she looked fine,” Liz says. Still concerned, though, Liz kept a close eye on Arielle over the next couple of days. That’s when she noticed something. “I noticed the slightest flicker of her eyes,” Liz recalls, “and decided that I wanted to get it checked out.” She took Arielle back to the hospital, asking them to do a CT scan. The hospital demurred, but Liz insisted, telling them she needed the peace of mind. “So they did the scan,” Liz recalls, “and they found an enormous tumor.” Read about Arielle and her family. Kyle Cooper waits 18 years for oral surgery Kyle at prom c/o VeraAnn Photography Kyle Cooper was born with hemifacial microsomia (HFM), a craniofacial anomaly that resulted in the left side of his face being underdeveloped. It meant his face was noticeably uneven and barely any of his teeth touched. “I made it through and got used...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: All posts Our patients’ stories Chiari Malformation concussion congenital heart defect Dr. Alex Taylor Dr. Ben Warf Dr. Bonnie Padwa Dr. Lawrence Karlin Dr. Michael O'brien Dr. Michael Scott Dr. Roger Nuss hemifacial microsomia Source Type: news

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Conclusion: Silent type 1 CNV is an established complication of chronic CSCR. SS-OCTA is indispensable in excluding CNV especially in high-risk patients and whenever FFA and SS-OCT are inconclusive. PMID: 29348931 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
We report a case of a 51-year-old man with NPC. PET-CT scan revealed a space-occupying lesion in the left lung, and the pathologic result confirmed the occupying lesion originated from NPC. Meanwhile, both immunohistochemistry and PCR revealed that the occupying lesion belonged to pMMR NPC. The lung lesions largely shrunk after chemoradiotherapy. One year later, MRI showed brain occupancy, and brain lesion resection surgery was performed subsequently. The resected tissue was also validated to be the metastatic lesion from NPC. After one month, the patient was examined again by PET-CT, which showed multiple metastases in th...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
In conclusion, our results showed that metformin is able to enhance TMZ effect in TMZ-resistant cell line suggesting its potential use in TMZ refractory GBM patients. However, the lack of effect on a GBM malignancy marker like CD133 requires further evaluation since it might influence response duration. PMID: 29348889 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Yang CH, Wang Y, Sims M, Cai C, He P, Häcker H, Yue J, Cheng J, Boop FA, Pfeffer LM Abstract Glioblastoma (GBM) is a deadly and incurable brain tumor. Although microRNAs (miRNAs) play critical roles in regulating the cancer cell phenotype, the underlying mechanisms of how they regulate tumorigenesis are incompletely understood. We previously showed that miR-203a is expressed at relatively low levels in GBM patients, and ectopic miR-203a expression in GBM cell lines inhibited cell proliferation and migration, increased sensitivity to apoptosis induced by interferon (IFN) or temozolomide in vitro, and i...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Gao Y, Han Y, Nan G, Hu M, Zhou X, Hu X Abstract Purposes: To develop a fast, accurate and robust method of fusing Computed Tomography (CT) with pre-operative Magnetic Resonance Imaging (MRI) and evaluate the impact of using the fused data on the implantation of Iodine-125 (125I) seeds for brachytherapy of high-grade gliomas (HGG). Methods: A study was performed on a cohort of 10 consecutive patients with HGG were treated by 125I brachytherapy with CT-MRI fusion image guided (CMGB), and 10 patients treated with CT alone guided (CGB). Statistical analysis was performed to compare (1) the planning target...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP Abstract Glioblastoma remains the most common, malignant primary cancer of the central nervous system with a low life expectancy and an overall survival of less than 1.5 years. The treatment options are limited and there is no cure. Moreover, almost all patients develop recurrent tumors, which typically are more aggressive. Therapeutically resistant glioblastoma or glioblastoma stem-like cells (GSCs) are hypothesized to cause this inevitable recurrence. Identifying prognost...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Manuel GE, Johnson T, Liu D Abstract Angiogenesis is the process through which new blood vessels are formed, while therapeutic angiogenesis aims to promote and control the angiogenic response. Ischemia results from the lack of blood flow with oxygen and nutrients. Therapeutic angiogenesis is crucial in preserving brain tissue and bodily functions after ischemic stroke. Various approaches have been proposed to promote angiogenesis in ischemic diseases. Traditional protein/gene and subsequent stem/progenitor cell approaches have not shown consistent efficacy for ischemic diseases in clinical trials. Exosomes...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research
CONCLUSION/CLINICAL RELEVANCE: Knee extension sessions with HAL®, and hip flexor and upper-limb-triggered HAL® ambulation seem a safe and feasible option in a patient with complete paraplegia due to spinal cord injury. PMID: 29351051 [PubMed - as supplied by publisher]
Source: Journal of Spinal Cord Medicine - Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research
Publication date: 10 March 2018 Source:Thermochimica Acta, Volume 661 Author(s): Amir Jangizehi, S. Reza Ghaffarian, Goolia Nikravan, Seifollah Jamalpour Thermal and viscoelastic properties of entangled supramolecular polymer networks, SPNs, depend strongly on binary and collective assembly of associative groups. The collective assemblies can phase separate from polymer matrix chains and form domains with different sizes and shapes, which have different melting point transitions. By increasing content of associative groups along the polymer chains, their high-order association leads to formation of domains, which have hig...
Source: Thermochimica Acta - Category: Chemistry Source Type: research
Publication date: 10 March 2018 Source:Thermochimica Acta, Volume 661 Author(s): Haibo Wang, Huiming Chen, Yue Ma, Hang Wang Rare earth elements are recently attracting more and more interests due to their dramatic effect as alloying elements. However the study regarding the phase equilibria between rare earth elements are still rare. The thermodynamically stable phases within the ∼50 at.%Y region have been investigated for the La-Y binary system using differential scanning calorimetry, scanning electron microscopy and transmission electron microscopy in the present work. The samarium-type δ-LaY has been found...
Source: Thermochimica Acta - Category: Chemistry Source Type: research
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