Genetically Proxied Autoimmune Diseases and the Risk of Facial Aging
CONCLUSION: These findings indicated that autoimmune diseases play a causal role in facial skin aging. Therefore, patients with autoimmune diseases should take appropriate measures to prevent early facial aging.PMID:38716190 | PMC:PMC11075699 | DOI:10.2147/CCID.S456126 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 8, 2024 Category: Dermatology Authors: Zhanyi Zhang Mengyuan Li Yujia Geng Wangshu Wang Weihao Wang Ying Shao Source Type: research

Surgical Treatment of Multiple Large Tuberous and Tendinous Xanthoma Secondary to Familial Hypercholesterolaemia: A Case Report
Clin Cosmet Investig Dermatol. 2024 Apr 29;17:961-966. doi: 10.2147/CCID.S445163. eCollection 2024.ABSTRACTXanthomas are well-circumscribed skin lesions that are commonly seen in patients with familial hypercholesterolemia (FH). The aim of this report is to present a rare case of multiple large tuberous and tendinous xanthomas. A 17-year-old female patient in this report presented with multiple asymptomatic and papulo-nodular masses in both sides of palms, elbows, buttocks, knees, and Achilles tendons. Surgical removal of the masses was carried out in combination with lipid-lowering therapy. A following up of 3 months show...
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Haonan Guan Guoyou Zhang Qiqi Li Jie Lian Zhaoyang Dong Lian Zhu Kaiyan Xiao Source Type: research

Long Non-Coding RNA B3GALT5-AS1 Suppresses Keloid Progression by Regulating the β-Trcp1-Mediated Ubiquitination of HuR
CONCLUSION: Our findings illustrate that B3GALT5-AS1 has great effect on inhibition of keloid formation, which provides a potential target for keloid therapy.PMID:38707608 | PMC:PMC11069380 | DOI:10.2147/CCID.S447772 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Wei Ye Junwen Lu Zuxian Yang Ben Yang Guanya Zhu Chunli Xue Source Type: research

Erratum: Sclerotherapy in Lymphatic Malformations with Intralesional Hemorrhage: A Retrospective Comparison with Non-Hemorrhagic Lymphatic Malformations [Corrigendum]
Clin Cosmet Investig Dermatol. 2024 Apr 24;17:911-912. doi: 10.2147/CCID.S474957. eCollection 2024.ABSTRACT[This corrects the article DOI: 10.2147/CCID.S386813.].PMID:38707609 | PMC:PMC11066658 | DOI:10.2147/CCID.S474957 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Source Type: research

Death Caused by Disseminated Herpes Zoster in a Patient with Multiple Myeloma: A Case Report and Literature Review
We report a fatal case of disseminated herpes zoster in a patient with multiple myeloma, illustrating the severe risks immunocompromised individuals face from viral infections. By combining a detailed case report with an extensive literature review, the paper seeks to shed light on the underlying susceptibility factors for varicella-zoster virus infection in multiple myeloma patients. We further evaluate effective prophylactic protocols for herpes zoster, aiming to equip clinicians with improved therapeutic strategies. The case underscores the critical need for vigilant clinical assessments and tailored patient management ...
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Yang Bo Xiaojing Zhong Yanping Xiang Qingjun Ren Pingsheng Hao Source Type: research

Surgical Treatment of Multiple Large Tuberous and Tendinous Xanthoma Secondary to Familial Hypercholesterolaemia: A Case Report
Clin Cosmet Investig Dermatol. 2024 Apr 29;17:961-966. doi: 10.2147/CCID.S445163. eCollection 2024.ABSTRACTXanthomas are well-circumscribed skin lesions that are commonly seen in patients with familial hypercholesterolemia (FH). The aim of this report is to present a rare case of multiple large tuberous and tendinous xanthomas. A 17-year-old female patient in this report presented with multiple asymptomatic and papulo-nodular masses in both sides of palms, elbows, buttocks, knees, and Achilles tendons. Surgical removal of the masses was carried out in combination with lipid-lowering therapy. A following up of 3 months show...
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Haonan Guan Guoyou Zhang Qiqi Li Jie Lian Zhaoyang Dong Lian Zhu Kaiyan Xiao Source Type: research

Long Non-Coding RNA B3GALT5-AS1 Suppresses Keloid Progression by Regulating the β-Trcp1-Mediated Ubiquitination of HuR
CONCLUSION: Our findings illustrate that B3GALT5-AS1 has great effect on inhibition of keloid formation, which provides a potential target for keloid therapy.PMID:38707608 | PMC:PMC11069380 | DOI:10.2147/CCID.S447772 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Wei Ye Junwen Lu Zuxian Yang Ben Yang Guanya Zhu Chunli Xue Source Type: research

Erratum: Sclerotherapy in Lymphatic Malformations with Intralesional Hemorrhage: A Retrospective Comparison with Non-Hemorrhagic Lymphatic Malformations [Corrigendum]
Clin Cosmet Investig Dermatol. 2024 Apr 24;17:911-912. doi: 10.2147/CCID.S474957. eCollection 2024.ABSTRACT[This corrects the article DOI: 10.2147/CCID.S386813.].PMID:38707609 | PMC:PMC11066658 | DOI:10.2147/CCID.S474957 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Source Type: research

Death Caused by Disseminated Herpes Zoster in a Patient with Multiple Myeloma: A Case Report and Literature Review
We report a fatal case of disseminated herpes zoster in a patient with multiple myeloma, illustrating the severe risks immunocompromised individuals face from viral infections. By combining a detailed case report with an extensive literature review, the paper seeks to shed light on the underlying susceptibility factors for varicella-zoster virus infection in multiple myeloma patients. We further evaluate effective prophylactic protocols for herpes zoster, aiming to equip clinicians with improved therapeutic strategies. The case underscores the critical need for vigilant clinical assessments and tailored patient management ...
Source: Clinical, Cosmetic and Investigational Dermatology - May 6, 2024 Category: Dermatology Authors: Yang Bo Xiaojing Zhong Yanping Xiang Qingjun Ren Pingsheng Hao Source Type: research

Four-Leaf Clover Shape Agglomerate Keratoacanthomas: A Case Report
Clin Cosmet Investig Dermatol. 2024 Apr 24;17:921-924. doi: 10.2147/CCID.S453734. eCollection 2024.ABSTRACTKeratoacanthoma (KA) is a papule, plaque, or nodule in an exposed area, with a crater-like horn plug in the center. Multiple KAs are rare disorders, especially when the lesions are agglomerated together. Herein, we report a case of 65-year-old man who presented with four red nodules of different sizes on the right side of the chest. The lesions were clustered, with central keratotic cores, similar in appearance to a four-leaf clover. The nodules were completely removed by excisional surgery and the diagnosis of Agglom...
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Dingbin Yang Yu Mao Lu Peng Shuqiong Huang Lijun Zhou Changqiang Li Source Type: research

A Frequent Diagnostic Pitfall: Dermatological Clinical Features and Pathological Results in Diagnosing Pagetoid Squamous Cell Carcinoma in situ (Case Series)
In this study, three patients underwent pathological routine and auxiliary immunohistochemical (IHC) examination and were ultimately diagnosed with pagetoid SCC in situ - a different diagnosis from the initial clinical assessment. All three patients received a complete resection of the skin mass. After follow-up, as of June 2023, the patients had no tumour recurrence or metastasis. Pagetoid SCC in situ is a particular type of SCC in situ that has no specific features in clinical manifestations, gross diagnosis or histopathological sections. The final diagnosis depends on IHC staining. Pagetoid SCC in situ expresses EMA, CK...
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Sheng-Kai Wang Jia-Wei Cai Yu Zhang Ya-Jing Lin Yi-Hui Yang Source Type: research

Dermatology Consultation in the Geriatrics Department of a Tertiary Hospital in China: A Retrospective Study of 178 Patients
CONCLUSION: This study summarized the reasons for dermatology consultations for geriatric inpatients and found that dermatitis/eczema and infectious diseases were the common types of diseases consulted. The findings of this study contribute to the enhanced comprehension and management of dermatological conditions in hospitalized patients by geriatricians, as well as facilitating more efficient diagnosis and treatment by dermatologists.PMID:38699408 | PMC:PMC11063470 | DOI:10.2147/CCID.S461156 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Lingyun Du Zhiqiang Cao Changyu Han Jingjing Wei Mingming Li Chunhong Zhang Source Type: research

Four-Leaf Clover Shape Agglomerate Keratoacanthomas: A Case Report
Clin Cosmet Investig Dermatol. 2024 Apr 24;17:921-924. doi: 10.2147/CCID.S453734. eCollection 2024.ABSTRACTKeratoacanthoma (KA) is a papule, plaque, or nodule in an exposed area, with a crater-like horn plug in the center. Multiple KAs are rare disorders, especially when the lesions are agglomerated together. Herein, we report a case of 65-year-old man who presented with four red nodules of different sizes on the right side of the chest. The lesions were clustered, with central keratotic cores, similar in appearance to a four-leaf clover. The nodules were completely removed by excisional surgery and the diagnosis of Agglom...
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Dingbin Yang Yu Mao Lu Peng Shuqiong Huang Lijun Zhou Changqiang Li Source Type: research

A Frequent Diagnostic Pitfall: Dermatological Clinical Features and Pathological Results in Diagnosing Pagetoid Squamous Cell Carcinoma in situ (Case Series)
In this study, three patients underwent pathological routine and auxiliary immunohistochemical (IHC) examination and were ultimately diagnosed with pagetoid SCC in situ - a different diagnosis from the initial clinical assessment. All three patients received a complete resection of the skin mass. After follow-up, as of June 2023, the patients had no tumour recurrence or metastasis. Pagetoid SCC in situ is a particular type of SCC in situ that has no specific features in clinical manifestations, gross diagnosis or histopathological sections. The final diagnosis depends on IHC staining. Pagetoid SCC in situ expresses EMA, CK...
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Sheng-Kai Wang Jia-Wei Cai Yu Zhang Ya-Jing Lin Yi-Hui Yang Source Type: research

Dermatology Consultation in the Geriatrics Department of a Tertiary Hospital in China: A Retrospective Study of 178 Patients
CONCLUSION: This study summarized the reasons for dermatology consultations for geriatric inpatients and found that dermatitis/eczema and infectious diseases were the common types of diseases consulted. The findings of this study contribute to the enhanced comprehension and management of dermatological conditions in hospitalized patients by geriatricians, as well as facilitating more efficient diagnosis and treatment by dermatologists.PMID:38699408 | PMC:PMC11063470 | DOI:10.2147/CCID.S461156 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 3, 2024 Category: Dermatology Authors: Lingyun Du Zhiqiang Cao Changyu Han Jingjing Wei Mingming Li Chunhong Zhang Source Type: research