Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 week...
Source: Anaerobe - November 25, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mary Paz Roche Matheus Mikel Urrutikoetxea Guti érrez Gotzon Iglesias Hidalgo Cristina Aspichueta Vivanco Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China
This study highlights the prevalence of MDR Enterococcus (≥88 %) and four ARGs (≥75 %) in swine (intensive farming), cattle (commercial farming), and chickens (backyard farming) are high and also highlights that optrA-carrying E. faecalis of farm animals incur a transmission risk to humans through environment, food consumption and others. Therefore, antibiotic-resistant bacteria (ARB) monitoring and effective control measures should be strengthened and implemented in diverse animals.PMID:37996027 | DOI:10.1016/j.scitotenv.2023.168683 (Source: Anal Sci)
Source: Anal Sci - November 23, 2023 Category: Chemistry Authors: Wanzhao Chen Qiaojun Wang Huimin Wu Panpan Xia Rui Tian Ruichao Li Lining Xia Source Type: research
Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China
This study highlights the prevalence of MDR Enterococcus (≥88 %) and four ARGs (≥75 %) in swine (intensive farming), cattle (commercial farming), and chickens (backyard farming) are high and also highlights that optrA-carrying E. faecalis of farm animals incur a transmission risk to humans through environment, food consumption and others. Therefore, antibiotic-resistant bacteria (ARB) monitoring and effective control measures should be strengthened and implemented in diverse animals.PMID:37996027 | DOI:10.1016/j.scitotenv.2023.168683 (Source: Anal Sci)
Source: Anal Sci - November 23, 2023 Category: Chemistry Authors: Wanzhao Chen Qiaojun Wang Huimin Wu Panpan Xia Rui Tian Ruichao Li Lining Xia Source Type: research
Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China
This study highlights the prevalence of MDR Enterococcus (≥88 %) and four ARGs (≥75 %) in swine (intensive farming), cattle (commercial farming), and chickens (backyard farming) are high and also highlights that optrA-carrying E. faecalis of farm animals incur a transmission risk to humans through environment, food consumption and others. Therefore, antibiotic-resistant bacteria (ARB) monitoring and effective control measures should be strengthened and implemented in diverse animals.PMID:37996027 | DOI:10.1016/j.scitotenv.2023.168683 (Source: Anal Sci)
Source: Anal Sci - November 23, 2023 Category: Chemistry Authors: Wanzhao Chen Qiaojun Wang Huimin Wu Panpan Xia Rui Tian Ruichao Li Lining Xia Source Type: research
Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China
This study highlights the prevalence of MDR Enterococcus (≥88 %) and four ARGs (≥75 %) in swine (intensive farming), cattle (commercial farming), and chickens (backyard farming) are high and also highlights that optrA-carrying E. faecalis of farm animals incur a transmission risk to humans through environment, food consumption and others. Therefore, antibiotic-resistant bacteria (ARB) monitoring and effective control measures should be strengthened and implemented in diverse animals.PMID:37996027 | DOI:10.1016/j.scitotenv.2023.168683 (Source: Anal Sci)
Source: Anal Sci - November 23, 2023 Category: Chemistry Authors: Wanzhao Chen Qiaojun Wang Huimin Wu Panpan Xia Rui Tian Ruichao Li Lining Xia Source Type: research
Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China
This study highlights the prevalence of MDR Enterococcus (≥88 %) and four ARGs (≥75 %) in swine (intensive farming), cattle (commercial farming), and chickens (backyard farming) are high and also highlights that optrA-carrying E. faecalis of farm animals incur a transmission risk to humans through environment, food consumption and others. Therefore, antibiotic-resistant bacteria (ARB) monitoring and effective control measures should be strengthened and implemented in diverse animals.PMID:37996027 | DOI:10.1016/j.scitotenv.2023.168683 (Source: Anal Sci)
Source: Anal Sci - November 23, 2023 Category: Chemistry Authors: Wanzhao Chen Qiaojun Wang Huimin Wu Panpan Xia Rui Tian Ruichao Li Lining Xia Source Type: research
Phenotypic drug-susceptibility profiles and genetic analysis based on whole-genome sequencing of < i > Mycobacterium avium < /i > complex isolates in Thailand
This study aimed to determine the drug-susceptibility profiles of MAC clinical isolates and to investigate the genetic basis conferring drug resistance using whole-genome sequencing (WGS) analysis. Drug-susceptibility profiles based on minimum inhibitory concentration (MIC) assays were determined for 38 MAC clinical isolates (12Mycobacterium avium and 26Mycobacterium intracellulare). Mutations associated with drug resistance were identified through genome analysis of these isolates, and their phylogenetic relationships were also examined. Drug resistance, based on MIC values, was most commonly observed for moxifloxacin (81...
Source: PLoS One - November 22, 2023 Category: Biomedical Science Authors: Auttawit Sirichoat Source Type: research
Availability of access, watch, and reserve (AWaRe) group of antibiotics in community pharmacies located close to a tertiary care hospital in Lalitpur, Nepal
ConclusionAntibiotics from the not recommended and reserve groups were commonly available in community pharmacies. The implementation of antibiotic guidelines should be emphasized along with strict monitoring of the sale of antibiotics without a prescription in community pharmacy settings. (Source: PLoS One)
Source: PLoS One - November 20, 2023 Category: Biomedical Science Authors: Nisha Jha Source Type: research
Short oral regimens for pulmonary rifampicin-resistant tuberculosis (TB-PRACTECAL): an open-label, randomised, controlled, phase 2B-3, multi-arm, multicentre, non-inferiority trial
Lancet Respir Med. 2023 Nov 15:S2213-2600(23)00389-2. doi: 10.1016/S2213-2600(23)00389-2. Online ahead of print.ABSTRACTBACKGROUND: Around 500 000 people worldwide develop rifampicin-resistant tuberculosis each year. The proportion of successful treatment outcomes remains low and new treatments are needed. Following an interim analysis, we report the final safety and efficacy outcomes of the TB-PRACTECAL trial, evaluating the safety and efficacy of oral regimens for the treatment of rifampicin-resistant tuberculosis.METHODS: This open-label, randomised, controlled, multi-arm, multicentre, non-inferiority trial was conducte...
Source: Respiratory Care - November 19, 2023 Category: Respiratory Medicine Authors: Bern-Thomas Nyang'wa Catherine Berry Emil Kazounis Ilaria Motta Nargiza Parpieva Zinaida Tigay Ronelle Moodliar Matthew Dodd Varvara Solodovnikova Irina Liverko Shakira Rajaram Mohammed Rassool Timothy McHugh Melvin Spigelman David A Moore Koert Ritmeijer Source Type: research
