Ceftriaxone-Resistant Gonorrhea - China, 2022
MMWR Morb Mortal Wkly Rep. 2024 Mar 28;73(12):255-259. doi: 10.15585/mmwr.mm7312a2.ABSTRACTGonorrhea is a widespread sexually transmitted infection; in 2022, China reported 96,313 cases of gonorrhea, making it the fourth most common notifiable infectious disease in the country after viral hepatitis, pulmonary tuberculosis, and syphilis. The rise in prevalence in antimicrobial-resistant strains, particularly the international spread of ceftriaxone-resistant clones, poses a formidable challenge to gonorrhea control. The China Gonococcal Resistance Surveillance Program (China-GRSP), established in 1987 and covering 19 of 34 p...
Source: MMWR Morb Mortal Wkl... - March 28, 2024 Category: Epidemiology Authors: Xiaoyu Zhu Yue Xi Xiangdong Gong Shaochun Chen Source Type: research

Ceftriaxone-Resistant Gonorrhea - China, 2022
MMWR Morb Mortal Wkly Rep. 2024 Mar 28;73(12):255-259. doi: 10.15585/mmwr.mm7312a2.ABSTRACTGonorrhea is a widespread sexually transmitted infection; in 2022, China reported 96,313 cases of gonorrhea, making it the fourth most common notifiable infectious disease in the country after viral hepatitis, pulmonary tuberculosis, and syphilis. The rise in prevalence in antimicrobial-resistant strains, particularly the international spread of ceftriaxone-resistant clones, poses a formidable challenge to gonorrhea control. The China Gonococcal Resistance Surveillance Program (China-GRSP), established in 1987 and covering 19 of 34 p...
Source: MMWR Morb Mortal Wkl... - March 28, 2024 Category: Epidemiology Authors: Xiaoyu Zhu Yue Xi Xiangdong Gong Shaochun Chen Source Type: research

Ceftriaxone-Resistant Gonorrhea - China, 2022
MMWR Morb Mortal Wkly Rep. 2024 Mar 28;73(12):255-259. doi: 10.15585/mmwr.mm7312a2.ABSTRACTGonorrhea is a widespread sexually transmitted infection; in 2022, China reported 96,313 cases of gonorrhea, making it the fourth most common notifiable infectious disease in the country after viral hepatitis, pulmonary tuberculosis, and syphilis. The rise in prevalence in antimicrobial-resistant strains, particularly the international spread of ceftriaxone-resistant clones, poses a formidable challenge to gonorrhea control. The China Gonococcal Resistance Surveillance Program (China-GRSP), established in 1987 and covering 19 of 34 p...
Source: MMWR Morb Mortal Wkl... - March 28, 2024 Category: Epidemiology Authors: Xiaoyu Zhu Yue Xi Xiangdong Gong Shaochun Chen Source Type: research

The Potentiation Activity of Azithromycin in Combination with Colistin or Levofloxacin Against Pseudomonas aeruginosa Biofilm Infection
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - March 28, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

ERS/EBMT clinical practice guidelines on treatment of pulmonary chronic graft-versus-host disease in adults
Chronic graft-versus-host disease (cGvHD) is a common complication after allogeneic haematopoietic stem cell transplantation, characterised by a broad disease spectrum that can affect virtually any organ. Although pulmonary cGvHD is a less common manifestation, it is of great concern due to its severity and poor prognosis. Optimal management of patients with pulmonary cGvHD is complicated and no standardised approach is available. The purpose of this joint European Respiratory Society (ERS) and European Society for Blood and Marrow Transplantation task force was to develop evidence-based recommendations regarding the treat...
Source: European Respiratory Journal - March 28, 2024 Category: Respiratory Medicine Authors: Bos, S., Murray, J., Marchetti, M., Cheng, G.-S., Bergeron, A., Wolff, D., Sander, C., Sharma, A., Badawy, S. M., Peric, Z., Piekarska, A., Pidala, J., Raj, K., Penack, O., Kulkarni, S., Beestrum, M., Linke, A., Rutter, M., Coleman, C., Tonia, T., Schoema Tags: Respiratory clinical practice Original Articles: ERS/EBMT guidelines Source Type: research

Improvement of Clinical Findings, Meibography and Tear Film Parameters in Pediatric Ocular Rosacea Patients After a Standard Treatment Protocol
CONCLUSION: This study demonstrated that pediatric ocular rosacea patients may exhibit improved meibomian gland function, regression of corneal neovascularization, and enhanced tear film parameters following a standardized treatment protocol that includes both topical and systemic approaches.PMID:38512290 | DOI:10.1080/09273948.2024.2328791 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 21, 2024 Category: Allergy & Immunology Authors: Ali Ceylan Irem Onal Fahri Onur Aydin Burak Mergen Yusuf Yildirim Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research

Efficacy of Single-Dose Azithromycin for Ocular Chlamydial Infection: A Longitudinal Study
In this study, four villages in Niger received a mass azithromycin distribution for trachoma. All 426 children aged 0-5 years residing in the study villages were offered conjunctival swabbing every 6 months to test for ocular Chlamydia trachomatis. Among the children infected with ocular Chlamydia before treatment, 6% (95% CI: 2-15%) tested positive for ocular Chlamydia infection 6 months later, and 15% (95% CI: 7-28%) tested positive 12 months later. The most important predictor of post-treatment ocular Chlamydia infection was pretreatment ocular Chlamydia infection (relative risk: 3.5, 95% CI: 1.3-9.4). Although the 6-mo...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Neha Pondicherry Amza Abdou Boubacar Kadri Beido Nassirou Sun Y Cotter Nicole E Varnado Travis C Porco Sheila K West Thomas M Lietman Jeremy D Keenan Source Type: research