Targeting antibiotic pollution: an investigation of azithromycin in wastewater by electrochemical surface-enhanced Raman spectroscopy
Canadian Journal of Chemistry, Ahead of Print. Azithromycin is a macrolide antibiotic that is commonly prescribed to treat infections of the skin, soft tissues, and the upper and lower respiratory tracts. Many antibiotics, including azithromycin, are overprescribed, leading to elevated concentrations of these drugs in bodies of water; this phenomenon is referred to as antibiotic pollution. Antibiotic pollution is increasingly concerning, due to its implications for the development of antibiotic resistance and its potential ecotoxicity. Rapid detection of azithromycin in wastewater could be important for addressing antibiot...
Source: Canadian Journal of Chemistry - February 6, 2024 Category: Chemistry Authors: Rachael B.E. Ball Christa L. Brosseau Source Type: research

The First Case of Mycobacterium interjectum Pulmonary Disease in Japan: A Case Report
Intern Med. 2024 Feb 5. doi: 10.2169/internalmedicine.2934-23. Online ahead of print.ABSTRACTWe herein report a case of Mycobacterium interjectum pulmonary disease (M. interjectum-PD) that improved considerably after azithromycin (AZM), rifampicin (RFP), and ethambutol (EB) therapy. A 69-year-old woman, managed locally for suspected NTM-PD based on chest computed tomography (CT) findings was referred to our hospital for worsening productive cough six years after the initial diagnosis. High-resolution chest CT showed right middle and left lower lobe bronchiectasis with middle and centrilobular nodules. Bronchial washing and...
Source: Internal Medicine - February 4, 2024 Category: Internal Medicine Authors: Asuka Yamaguchi Naohisa Urabe Nozomi Tokita Masakazu Sasaki Noboru Iizuka Susumu Sakamoto Kazuma Kishi Source Type: research

Factors affecting prognosis and mortality in severe covid-19 pneumonia patients
Acta Clin Croat. 2023 Apr;62(1):106-114. doi: 10.20471/acc.2023.62.01.13.ABSTRACTFatality rate in coronavirus disease 2019 (COVID-19) cases has been reported to be 3.4% worldwide. The aim of this study was to evaluate the factors that determine prognosis and mortality in severe COVID-19 pneumonia patients. Eighty adult patients with severe COVID-19 pneumonia hospitalized and monitored at Izzet Baysal State Hospital (Bolu, Turkey) between August and November 2020 were included in this retrospective single-center study. Demographic and laboratory data, severity of radiological involvement, comorbidities, agents used in treat...
Source: Acta Clinica Croatica - February 2, 2024 Category: General Medicine Authors: Emine Af şin Muhammed Emin Demirkol Source Type: research