Efficacy of cyclocryotherapy and transscleral diode laser cyclophotocoagulation in the management of refractory glaucoma
In conclusion, study results confirmed the CCT and TS-DCPC to have a rapid and statistically significant ocular hypotensive effect in eyes with refractory glaucoma at one-year follow-up.PMID:34744265 | PMC:PMC8564844 | DOI:10.20471/acc.2021.60.02.01 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Aleksandar Miljkovi ć Nikola Babi ć Vladimir Čanadanović Sofija Davidovi ć Jelena Ljikar Marija Vasin Source Type: research

The cost of kidney transplantation at the merkur university hospital, zagreb, croatia
Acta Clin Croat. 2021 Jun;60(2):178-183. doi: 10.20471/acc.2021.60.02.02.ABSTRACTThe aim was to determine the cost of hospitalization for a transplant procedure and identify the independent variables associated with the cost of transplantation. The investigation was designed as a retrospective single-center cohort study conducted at a tertiary university hospital transplant center in Zagreb, Croatia. The study included 219 consecutive kidney recipients transplanted during the 2007-2013 period at the Merkur University Hospital. There were 141 male and 78 female patients having undergone kidney transplantation during the stu...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ivan Neretljak Mario Su čić Branislav Kocman Mladen Knotek Source Type: research

Our experience with contrast-enhanced voiding urosonography
This study compared characteristics associated with VUR specific images and categorized patients according to a particular VUR grade. The study included 183 children. VUR was detected in 38.9% of patients, mean age 1.7±1.1 years. Grade II VUR was most common (60.3%), followed by grade III (29.4%). Study results showed that VUR occurred irrespective of age, gender, previous ultrasound findings, causative agent, and severity of urinary tract infection (UTI). VUR was more common in children with recurrent UTI. In the group of children with the first UTI not caused by Escherichia coli or with recurrent UTI, boys more co...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Karla Rubelj Lea Oleti ć Bernardica Valent Mori ć Ivana Trutin Source Type: research

Plantar sensation and balance in patients with type 2 diabetes mellitus with and without peripheral neuropathy
Acta Clin Croat. 2021 Jun;60(2):191-200. doi: 10.20471/acc.2021.60.02.04.ABSTRACTThe aim of the study was to investigate the effect of diabetes on plantar sense and balance in patients with type 2 diabetes mellitus (T2DM). The study included 300 subjects divided into three groups: 100 T2DM patients with diabetic peripheral neuropathy (group 1); 100 T2DM patients without peripheral neuropathy (group 2); and 100 subjects without DM (group 3). Berg Balance Scale (BBS), Timed Up and Go test (TUG), single leg test with eyes open and closed, and plantar sensory tests were applied in the subjects. Study results showed significant...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Eylem T ütün Yümin T ülay Tarsuslu Şimşek Ye şim Bakar Source Type: research

The role of anthropometric parameters and physical activity level in patients with acute coronary syndrome admitted to the intensive cardiac care unit
Acta Clin Croat. 2021 Jun;60(2):201-208. doi: 10.20471/acc.2021.60.02.05.ABSTRACTAnthropometric parameters have a role in diagnosing obesity, which increases the risk of acute coronary syndrome (ACS). The aim of the study was to assess the impact of obesity and physical activity level on the severity and long-term prognosis of ACS. A total of 116 patients with ACS were analyzed according to baseline (demography, medical history, anthropometry), severity (clinical presentation, in-hospital complications, laboratory, echocardiography, coronary angiography) and prognostic parameters (major adverse cardiovascular events during...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Zdravko Babi ć Ivan Zeljkovi ć Hrvoje Pintari ć Mislav Vrsalovi ć Marko Mornar Jelavi ć Marjeta Mi šigoj-Duraković Source Type: research

Assessment of cytogenetic damage to exfoliated gingival cells in patients with chronic generalized periodontitis
Acta Clin Croat. 2021 Jun;60(2):209-215. doi: 10.20471/acc.2021.60.02.06.ABSTRACTThe aim of this cross-sectional study was to investigate the occurrence of chromosomal abnormalities through the frequency of micronuclei and other genomic damage markers in patients with chronic generalized periodontitis and without periodontal disease. Micronucleus assay was performed in exfoliated gingival epithelial cells of 35 patients with generalized chronic periodontitis and 30 control subjects with healthy periodontium. Full mouth clinical examination was performed to define periodontal condition. The mean number of cells with micronu...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Antonija Tadin Lidia Gavi ć Marija Rogulji ć Mario Babi ć Ivan Gali ć Davor Želježić Source Type: research

A cross-sectional study of hepatitis b and hepatitis c knowledge among dental medicine students at the university of zagreb
In conclusion, DMS have low levels of knowledge on important occupational pathogens and poor NSI reporting practice. Moreover, formal education in the current form has failed to significantly improve student competence and theoretical knowledge translates poorly into more conscientious injury reporting practice. We should look for a better way to increase student awareness and level of knowledge on this topic.PMID:34744271 | PMC:PMC8564850 | DOI:10.20471/acc.2021.60.02.07 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Jan Homolak Deni Tomljanovi ć Milan Milo šević Domagoj Vra žić Mario Živković Ivan Budimir Borka Pezo Nikoli ć Antonela Muslim Neven Ljubi čić Marko Nikoli ć Source Type: research

The effect of primary argon laser trabeculoplasty on intraocular pressure reduction and quality of life in patients with pseudoexfoliation glaucoma
Acta Clin Croat. 2021 Jun;60(2):231-236. doi: 10.20471/acc.2021.60.02.08.ABSTRACTThe aim of the study was to assess the impact of primary argon laser trabeculoplasty (ALT) on intraocular pressure (IOP) lowering and quality of life improvement in patients with pseudoexfoliative glaucoma. Sixty patients with newly diagnosed pseudoexfoliative glaucoma who underwent primary ALT (group 2) or medication therapy (group 1) were followed-up. The effect of ALT on IOP reduction, dry eye development and number of antiglaucoma drugs used was examined. Patients were examined at the beginning of the study and then after 6, 12, and 18 mon...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Du šan Todorović Tatjana Šarenac Vulović Sun čica Srećković Svetlana Jovanovi ć Nenad Petrovi ć Source Type: research

CROATIAN VERSION OF THE QUALITY OF RECOVERY QUESTIONNAIRE (QoR-40): TRANSCULTURAL ADAPTATION AND VALIDATION
In conclusion, the Croatian version of the QoR-40 has acceptable properties and can be used in the assessment of postoperative recovery in Croatian patients.PMID:34744273 | PMC:PMC8564846 | DOI:10.20471/acc.2021.60.02.09 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Martina Mikli ć Bublić Pavle Mikli ć Petra Barl Marijana Matas Ante Sekuli ć Source Type: research

Isolated maternal hypothyroxinemia and its perinatal outcome in north macedonia
Acta Clin Croat. 2021 Jun;60(2):246-253. doi: 10.20471/acc.2021.60.02.10.ABSTRACTIsolated maternal hypothyroxinemia (IMH) is defined as the presence of low maternal total thyroxine (TT4) level in conjunction with normal maternal thyroid-stimulating hormone (TSH) level. The aim was to investigate whether IMH is associated with adverse pregnancy outcome in North Macedonia. Dried blood spot samples were obtained from 359 pregnant women meeting the inclusion criteria and analyzed for TT4 and TSH. Postpartum data were entered from their medical histories. Out of 359 women, 131 (37.42%) belonged to IMH group. There were statisti...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Maja Avramovska Borislav Karanfilski Goran Dimitrov Elena Dzikova Ana Daneva Markova Marija Hadzi Lega Gligor Tofoski Aleksandar Sikole Source Type: research

Building the covid-19 testing capacities in croatia: establishing the interdepartmental covid-19 unit at the split university hospital centre
We describe the processes from March 12, 2020 to May 26, 2020, starting from the initial knowledge transfer, expert team formation and management, testing implementation, and concluding with the standalone testing facilities, which used automated processes sufficient to meet testing requirements at that time. In the case presented, the COVID-19 unit was organized by joining human and laboratory resources from five clinical departments at the Split University Hospital Centre. Sample preparation procedures and analyses were launched within the restricted time frame while simultaneously training and organizing new laboratory ...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Nenad Kunac Jo ško Bezić Arijana Vuko Željana Bašić Ivan Jerkovi ć Ivana Kru žić Toni Ljubi ć Bernarda Lozi ć Sanda Sardeli ć Šimun Anđelinović Source Type: research

Iodine status and thyroid function in lactating women and infants - a survey in the zagreb area, croatia
Acta Clin Croat. 2021 Jun;60(2):259-267. doi: 10.20471/acc.2021.60.02.12.ABSTRACTLactating women (LW) and infants have high dietary iodine requirements and are at risk of iodine deficiency. The aim of the study was to assess iodine status and thyroid function in LW and their breastfed infants in Zagreb, Croatia. The study included 133 LW and breastfed infant pairs. Urinary iodine concentration (UIC) and thyroid function parameters were measured in all subjects. In LW, breast milk iodine concentration (BMIC) was measured and iodine and salt rich food frequency questionnaire data were collected. Results of analysis indicated...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Marina Prpi ć Maja Franceschi Valentina Vidranski Maria Andersson Michael B Zimmermann Sandra Hunziker Milan Milo šević Zvonko Kusi ć Tomislav Juki ć Source Type: research

Analgesic effect of tramadol is not altered by postoperative systemic inflammation after major abdominal surgery
Acta Clin Croat. 2021 Jun;60(2):268-275. doi: 10.20471/acc.2021.60.02.13.ABSTRACTTramadol is a commonly used analgesic in intensive care units (ICUs) for acute postoperative pain. Conversion of tramadol into active metabolites may be impaired in inflammatory states. Catechol-O-methyltransferase may influence pain. The aim of the study was to examine differences in the analgesic effect of tramadol between ICU patients with and without signs of systemic inflammation. Forty-three patients were admitted to ICU after a major abdominal surgery. The patients received a dose of 100 mg of tramadol intravenously every 6 hours during...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Nenad Ne šković Sa ška Marczi Dario Mandi ć Boris Mraovic Sonja Škiljić Gordana Kristek Hrvoje Vinkovi ć Slavica Kvolik Source Type: research

Assessment of allergies to food and additives in patients with angioedema, burning mouth syndrome, cheilitis, gingivostomatitis, oral lichenoid reactions, and perioral dermatitis
Acta Clin Croat. 2021 Jun;60(2):276-281. doi: 10.20471/acc.2021.60.02.14.ABSTRACTOral cavity and perioral area are constantly exposed to a variety of antigens, including food and additives, which have a potential role in the development of different oral mucosal and perioral cutaneous diseases since they can cause hypersensitivity reactions. Oral and perioral diseases mainly include angioedema, burning mouth syndrome, cheilitis, gingivostomatitis, oral lichenoid reactions, and perioral dermatitis. Previous studies were focused on delayed-type oral allergies by performing patch testing but did not include tests for immediat...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Iva Domi ć Jozo Budmir Ina Novak Marinka Mravak-Stipeti ć Liborija Lugovi ć-Mihić Source Type: research

Functional classification of children with cerebral palsy in krapina-zagorje county
Acta Clin Croat. 2021 Jun;60(2):282-289. doi: 10.20471/acc.2021.60.02.15.ABSTRACTThe aim was to study functional abilities and to create functional classification of children with cerebral palsy (CP) in Krapina-Zagorje County, based on the classification of gross and fine motor skills and associated impairments. Classification was performed according to the SCPE (Surveillance of Cerebral Palsy in Europe) criteria. We used standardized and complementary functional classification systems for cerebral palsy to create a functional profile. Research included 44 children with CP in the age range of 4 to 18 years. The results sho...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Sun čica Martinec Gordana Cesarec Ana Marija Tome čak Krilić Tomislav Rado šević Žarko Bakran Vlatka Meja ški Bošnjak Source Type: research

Risk assessment in pregnancy among women aged over forty
The objective of this study was to assess the relationship between women's age and risk of pregnancy-related complications. The study was a retrospective cohort analysis of the pregnancy-related complications and outcomes between two age groups of parturient women. Categorical data were expressed as absolute and relative frequencies. Statistical analysis was performed using χ2-test. The incidence of gestational diabetes was higher in the 40-47 age group as compared with the 20-24 age group. The rates of hypertension, preeclampsia, intrahepatic cholestasis of pregnancy and hypothyroidism did not differ between the two g...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ana-Meyra Potkonjak Ivka Djakovi ć Senka Sabolovi ć Rudman Lara Poljak Vesna Ko šec Source Type: research

The safety and efficacy of robot-assisted stereotactic biopsy for brain glioma: earliest institutional experiences and evaluation of literature
In conclusion, considering the preliminary results of our early experiences, robot-assisted tumor biopsy was proven to be a feasible and accurate procedure when surgery for brain glioma was not an option. It may increase safety and precision, without expanding surgical time, being similarly effective when compared to standard stereotactic and manual biopsy. Using this method to provide accurate sampling for histopathologic and immunohistochemical analysis is a safe and easy way to determine management strategies and outcome of different types of brain glioma.PMID:34744281 | PMC:PMC8564848 | DOI:10.20471/acc.2021.60.02.17 (...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Kre šimir Rotim Bruno Splavski Filip Vrban Source Type: research

Cognitive and psychotic symptoms in a patient with infratentorial arachnoid cyst: case report
We present a case of a patient with treatment resistant hallucinatory experiences with incidental finding of an arachnoid cyst localized in the posterior infratentorial cranial fossa dorsally to the cerebellum. Psychological testing revealed significant deficit of cognitive functions to the level of mild intellectual disability in a person that had previously finished high school with good grades. A combination of clozapine and lamotrigine led to significant improvement in mood and reduction of hallucinations, but without improvement in cognitive functions. We also performed a literature review of previously published case...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Maja Škarić Branka Aukst Margeti ć Anamarija Bogovi ć Dijaković Dalibor Karlovi ć Source Type: research

Erector spinae plane block and placement of perineural catheter for developmental hip disorder surgery in children
We report on a case of effective intraoperative analgesia achieved by ultrasound-guided lumbar ESP block and another case of effective intra- and postoperative analgesia accomplished with perineural catheter placement in addition to lumbar ESP block, both performed in children surgically treated for developmental hip disorders.PMID:34744283 | PMC:PMC8564838 | DOI:10.20471/acc.2021.60.02.19 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Emil Bosinci Svetolik Spasi ć Maja Mitrovi ć Marija Stevi ć Irena Simi ć Du šica Simić Source Type: research

Concurrent deep vein thrombosis and pulmonary embolism associated with hyperthyroidism: a case report
We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.PMID:34744284 | PMC:PMC8564842 | DOI:10.20471/acc.2021.60.02.20 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Josip Kati ć Ana Kati ć Karla Kati ć Darko Duplan čić Mislav Lozo Source Type: research

Spontaneous resolution of a nonfunctioning pituitary adenoma over one-month period: a case report
Acta Clin Croat. 2021 Jun;60(2):317-322. doi: 10.20471/acc.2021.60.02.21.ABSTRACTSpontaneous resolution of nonfunctioning pituitary adenoma after hemorrhagic apoplexy is a rare clinical entity of unknown etiology and is defined as disappearance of a tumor without any specific treatment. Here we present a 54-year-old male patient who presented with acute onset of severe headache, vomiting, photophobia, and sonophobia. He was referred to brain computed tomography, which showed a 16x12x16 mm tumor mass located in the sellar region with signs of hemorrhage. Endocrinologic evaluation was consistent with under-function of pituit...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Luka Komi ć Ivan Kruljac Gorana Miro šević Petar Ga ćina Hrvoje Ivan Pe ćina Vatroslav Čerina Domagoj Gajski Kristina Blaslov Kre šimir Rotim Milan Vrkljan Source Type: research

Benign multicystic peritoneal mesothelioma mimicking gynecologic pathology
We report a case of a a 21-year-old female patient who presented with unclear diffuse abdominal pain. Transvaginal ultrasound and magnetic resonance imaging of the abdomen and pelvis revealed multiple functional cysts in the projection of the right and left ovary and free fluid in the pouch of Douglas. Laparoscopy was performed and multicystic tumor with thin, smooth walls, filled with clear serous content was found in lesser pelvis spreading to the left paracolic region and under the spleen. The multicystic mass was removed. Histologic examination revealed cystic formations filled with mucous content and formed from conne...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ilija Alvir Boris Bevanda Damir Danoli ć Ivica Mami ć Lucija Kosti ć Angelina Star čević-Božović Mario Puljiz Source Type: research

Atypical mri findings in cerebral adrenoleukodystrophy: a case report
We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral symmetric frontal lobe white matter changes suggesting anterior predominance.PMID:34744287 | PMC:PMC8564837 | DOI:10.20471/acc.2021.60.02.23 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Koray Ko ç Arzu Canan P ınar Koç Kamil Karaali Özgür Duman Utku Şenol Source Type: research

Ureteral triplication accidentally found during cervical carcinoma operation
We report a case of a 38-year-old female patient diagnosed with cervical carcinoma, where ureteral triplication was detected incidentally during a radical operative procedure.PMID:34744288 | PMC:PMC8564831 | DOI:10.20471/acc.2021.60.02.24 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Dra žan Butorac Ivka Djakovi ć Jasminka Mal čić Ljubomir Jokanovi ć Source Type: research

Historical review
Acta Clin Croat. 2021 Jun;60(2):332.NO ABSTRACTPMID:34744289 | PMC:PMC8564847 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Tanja Su šec Source Type: research

On notable books in our history
Acta Clin Croat. 2021 Jun;60(2):333.NO ABSTRACTPMID:34744290 | PMC:PMC8564852 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Tanja Su šec Source Type: research

Efficacy of cyclocryotherapy and transscleral diode laser cyclophotocoagulation in the management of refractory glaucoma
In conclusion, study results confirmed the CCT and TS-DCPC to have a rapid and statistically significant ocular hypotensive effect in eyes with refractory glaucoma at one-year follow-up.PMID:34744265 | PMC:PMC8564844 | DOI:10.20471/acc.2021.60.02.01 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Aleksandar Miljkovi ć Nikola Babi ć Vladimir Čanadanović Sofija Davidovi ć Jelena Ljikar Marija Vasin Source Type: research

The cost of kidney transplantation at the merkur university hospital, zagreb, croatia
Acta Clin Croat. 2021 Jun;60(2):178-183. doi: 10.20471/acc.2021.60.02.02.ABSTRACTThe aim was to determine the cost of hospitalization for a transplant procedure and identify the independent variables associated with the cost of transplantation. The investigation was designed as a retrospective single-center cohort study conducted at a tertiary university hospital transplant center in Zagreb, Croatia. The study included 219 consecutive kidney recipients transplanted during the 2007-2013 period at the Merkur University Hospital. There were 141 male and 78 female patients having undergone kidney transplantation during the stu...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ivan Neretljak Mario Su čić Branislav Kocman Mladen Knotek Source Type: research

Our experience with contrast-enhanced voiding urosonography
This study compared characteristics associated with VUR specific images and categorized patients according to a particular VUR grade. The study included 183 children. VUR was detected in 38.9% of patients, mean age 1.7±1.1 years. Grade II VUR was most common (60.3%), followed by grade III (29.4%). Study results showed that VUR occurred irrespective of age, gender, previous ultrasound findings, causative agent, and severity of urinary tract infection (UTI). VUR was more common in children with recurrent UTI. In the group of children with the first UTI not caused by Escherichia coli or with recurrent UTI, boys more co...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Karla Rubelj Lea Oleti ć Bernardica Valent Mori ć Ivana Trutin Source Type: research

Plantar sensation and balance in patients with type 2 diabetes mellitus with and without peripheral neuropathy
Acta Clin Croat. 2021 Jun;60(2):191-200. doi: 10.20471/acc.2021.60.02.04.ABSTRACTThe aim of the study was to investigate the effect of diabetes on plantar sense and balance in patients with type 2 diabetes mellitus (T2DM). The study included 300 subjects divided into three groups: 100 T2DM patients with diabetic peripheral neuropathy (group 1); 100 T2DM patients without peripheral neuropathy (group 2); and 100 subjects without DM (group 3). Berg Balance Scale (BBS), Timed Up and Go test (TUG), single leg test with eyes open and closed, and plantar sensory tests were applied in the subjects. Study results showed significant...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Eylem T ütün Yümin T ülay Tarsuslu Şimşek Ye şim Bakar Source Type: research

The role of anthropometric parameters and physical activity level in patients with acute coronary syndrome admitted to the intensive cardiac care unit
Acta Clin Croat. 2021 Jun;60(2):201-208. doi: 10.20471/acc.2021.60.02.05.ABSTRACTAnthropometric parameters have a role in diagnosing obesity, which increases the risk of acute coronary syndrome (ACS). The aim of the study was to assess the impact of obesity and physical activity level on the severity and long-term prognosis of ACS. A total of 116 patients with ACS were analyzed according to baseline (demography, medical history, anthropometry), severity (clinical presentation, in-hospital complications, laboratory, echocardiography, coronary angiography) and prognostic parameters (major adverse cardiovascular events during...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Zdravko Babi ć Ivan Zeljkovi ć Hrvoje Pintari ć Mislav Vrsalovi ć Marko Mornar Jelavi ć Marjeta Mi šigoj-Duraković Source Type: research

Assessment of cytogenetic damage to exfoliated gingival cells in patients with chronic generalized periodontitis
Acta Clin Croat. 2021 Jun;60(2):209-215. doi: 10.20471/acc.2021.60.02.06.ABSTRACTThe aim of this cross-sectional study was to investigate the occurrence of chromosomal abnormalities through the frequency of micronuclei and other genomic damage markers in patients with chronic generalized periodontitis and without periodontal disease. Micronucleus assay was performed in exfoliated gingival epithelial cells of 35 patients with generalized chronic periodontitis and 30 control subjects with healthy periodontium. Full mouth clinical examination was performed to define periodontal condition. The mean number of cells with micronu...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Antonija Tadin Lidia Gavi ć Marija Rogulji ć Mario Babi ć Ivan Gali ć Davor Želježić Source Type: research

A cross-sectional study of hepatitis b and hepatitis c knowledge among dental medicine students at the university of zagreb
In conclusion, DMS have low levels of knowledge on important occupational pathogens and poor NSI reporting practice. Moreover, formal education in the current form has failed to significantly improve student competence and theoretical knowledge translates poorly into more conscientious injury reporting practice. We should look for a better way to increase student awareness and level of knowledge on this topic.PMID:34744271 | PMC:PMC8564850 | DOI:10.20471/acc.2021.60.02.07 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Jan Homolak Deni Tomljanovi ć Milan Milo šević Domagoj Vra žić Mario Živković Ivan Budimir Borka Pezo Nikoli ć Antonela Muslim Neven Ljubi čić Marko Nikoli ć Source Type: research

The effect of primary argon laser trabeculoplasty on intraocular pressure reduction and quality of life in patients with pseudoexfoliation glaucoma
Acta Clin Croat. 2021 Jun;60(2):231-236. doi: 10.20471/acc.2021.60.02.08.ABSTRACTThe aim of the study was to assess the impact of primary argon laser trabeculoplasty (ALT) on intraocular pressure (IOP) lowering and quality of life improvement in patients with pseudoexfoliative glaucoma. Sixty patients with newly diagnosed pseudoexfoliative glaucoma who underwent primary ALT (group 2) or medication therapy (group 1) were followed-up. The effect of ALT on IOP reduction, dry eye development and number of antiglaucoma drugs used was examined. Patients were examined at the beginning of the study and then after 6, 12, and 18 mon...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Du šan Todorović Tatjana Šarenac Vulović Sun čica Srećković Svetlana Jovanovi ć Nenad Petrovi ć Source Type: research

CROATIAN VERSION OF THE QUALITY OF RECOVERY QUESTIONNAIRE (QoR-40): TRANSCULTURAL ADAPTATION AND VALIDATION
In conclusion, the Croatian version of the QoR-40 has acceptable properties and can be used in the assessment of postoperative recovery in Croatian patients.PMID:34744273 | PMC:PMC8564846 | DOI:10.20471/acc.2021.60.02.09 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Martina Mikli ć Bublić Pavle Mikli ć Petra Barl Marijana Matas Ante Sekuli ć Source Type: research

Isolated maternal hypothyroxinemia and its perinatal outcome in north macedonia
Acta Clin Croat. 2021 Jun;60(2):246-253. doi: 10.20471/acc.2021.60.02.10.ABSTRACTIsolated maternal hypothyroxinemia (IMH) is defined as the presence of low maternal total thyroxine (TT4) level in conjunction with normal maternal thyroid-stimulating hormone (TSH) level. The aim was to investigate whether IMH is associated with adverse pregnancy outcome in North Macedonia. Dried blood spot samples were obtained from 359 pregnant women meeting the inclusion criteria and analyzed for TT4 and TSH. Postpartum data were entered from their medical histories. Out of 359 women, 131 (37.42%) belonged to IMH group. There were statisti...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Maja Avramovska Borislav Karanfilski Goran Dimitrov Elena Dzikova Ana Daneva Markova Marija Hadzi Lega Gligor Tofoski Aleksandar Sikole Source Type: research

Building the covid-19 testing capacities in croatia: establishing the interdepartmental covid-19 unit at the split university hospital centre
We describe the processes from March 12, 2020 to May 26, 2020, starting from the initial knowledge transfer, expert team formation and management, testing implementation, and concluding with the standalone testing facilities, which used automated processes sufficient to meet testing requirements at that time. In the case presented, the COVID-19 unit was organized by joining human and laboratory resources from five clinical departments at the Split University Hospital Centre. Sample preparation procedures and analyses were launched within the restricted time frame while simultaneously training and organizing new laboratory ...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Nenad Kunac Jo ško Bezić Arijana Vuko Željana Bašić Ivan Jerkovi ć Ivana Kru žić Toni Ljubi ć Bernarda Lozi ć Sanda Sardeli ć Šimun Anđelinović Source Type: research

Iodine status and thyroid function in lactating women and infants - a survey in the zagreb area, croatia
Acta Clin Croat. 2021 Jun;60(2):259-267. doi: 10.20471/acc.2021.60.02.12.ABSTRACTLactating women (LW) and infants have high dietary iodine requirements and are at risk of iodine deficiency. The aim of the study was to assess iodine status and thyroid function in LW and their breastfed infants in Zagreb, Croatia. The study included 133 LW and breastfed infant pairs. Urinary iodine concentration (UIC) and thyroid function parameters were measured in all subjects. In LW, breast milk iodine concentration (BMIC) was measured and iodine and salt rich food frequency questionnaire data were collected. Results of analysis indicated...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Marina Prpi ć Maja Franceschi Valentina Vidranski Maria Andersson Michael B Zimmermann Sandra Hunziker Milan Milo šević Zvonko Kusi ć Tomislav Juki ć Source Type: research

Analgesic effect of tramadol is not altered by postoperative systemic inflammation after major abdominal surgery
Acta Clin Croat. 2021 Jun;60(2):268-275. doi: 10.20471/acc.2021.60.02.13.ABSTRACTTramadol is a commonly used analgesic in intensive care units (ICUs) for acute postoperative pain. Conversion of tramadol into active metabolites may be impaired in inflammatory states. Catechol-O-methyltransferase may influence pain. The aim of the study was to examine differences in the analgesic effect of tramadol between ICU patients with and without signs of systemic inflammation. Forty-three patients were admitted to ICU after a major abdominal surgery. The patients received a dose of 100 mg of tramadol intravenously every 6 hours during...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Nenad Ne šković Sa ška Marczi Dario Mandi ć Boris Mraovic Sonja Škiljić Gordana Kristek Hrvoje Vinkovi ć Slavica Kvolik Source Type: research

Assessment of allergies to food and additives in patients with angioedema, burning mouth syndrome, cheilitis, gingivostomatitis, oral lichenoid reactions, and perioral dermatitis
Acta Clin Croat. 2021 Jun;60(2):276-281. doi: 10.20471/acc.2021.60.02.14.ABSTRACTOral cavity and perioral area are constantly exposed to a variety of antigens, including food and additives, which have a potential role in the development of different oral mucosal and perioral cutaneous diseases since they can cause hypersensitivity reactions. Oral and perioral diseases mainly include angioedema, burning mouth syndrome, cheilitis, gingivostomatitis, oral lichenoid reactions, and perioral dermatitis. Previous studies were focused on delayed-type oral allergies by performing patch testing but did not include tests for immediat...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Iva Domi ć Jozo Budmir Ina Novak Marinka Mravak-Stipeti ć Liborija Lugovi ć-Mihić Source Type: research

Functional classification of children with cerebral palsy in krapina-zagorje county
Acta Clin Croat. 2021 Jun;60(2):282-289. doi: 10.20471/acc.2021.60.02.15.ABSTRACTThe aim was to study functional abilities and to create functional classification of children with cerebral palsy (CP) in Krapina-Zagorje County, based on the classification of gross and fine motor skills and associated impairments. Classification was performed according to the SCPE (Surveillance of Cerebral Palsy in Europe) criteria. We used standardized and complementary functional classification systems for cerebral palsy to create a functional profile. Research included 44 children with CP in the age range of 4 to 18 years. The results sho...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Sun čica Martinec Gordana Cesarec Ana Marija Tome čak Krilić Tomislav Rado šević Žarko Bakran Vlatka Meja ški Bošnjak Source Type: research

Risk assessment in pregnancy among women aged over forty
The objective of this study was to assess the relationship between women's age and risk of pregnancy-related complications. The study was a retrospective cohort analysis of the pregnancy-related complications and outcomes between two age groups of parturient women. Categorical data were expressed as absolute and relative frequencies. Statistical analysis was performed using χ2-test. The incidence of gestational diabetes was higher in the 40-47 age group as compared with the 20-24 age group. The rates of hypertension, preeclampsia, intrahepatic cholestasis of pregnancy and hypothyroidism did not differ between the two g...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ana-Meyra Potkonjak Ivka Djakovi ć Senka Sabolovi ć Rudman Lara Poljak Vesna Ko šec Source Type: research

The safety and efficacy of robot-assisted stereotactic biopsy for brain glioma: earliest institutional experiences and evaluation of literature
In conclusion, considering the preliminary results of our early experiences, robot-assisted tumor biopsy was proven to be a feasible and accurate procedure when surgery for brain glioma was not an option. It may increase safety and precision, without expanding surgical time, being similarly effective when compared to standard stereotactic and manual biopsy. Using this method to provide accurate sampling for histopathologic and immunohistochemical analysis is a safe and easy way to determine management strategies and outcome of different types of brain glioma.PMID:34744281 | PMC:PMC8564848 | DOI:10.20471/acc.2021.60.02.17 (...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Kre šimir Rotim Bruno Splavski Filip Vrban Source Type: research

Cognitive and psychotic symptoms in a patient with infratentorial arachnoid cyst: case report
We present a case of a patient with treatment resistant hallucinatory experiences with incidental finding of an arachnoid cyst localized in the posterior infratentorial cranial fossa dorsally to the cerebellum. Psychological testing revealed significant deficit of cognitive functions to the level of mild intellectual disability in a person that had previously finished high school with good grades. A combination of clozapine and lamotrigine led to significant improvement in mood and reduction of hallucinations, but without improvement in cognitive functions. We also performed a literature review of previously published case...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Maja Škarić Branka Aukst Margeti ć Anamarija Bogovi ć Dijaković Dalibor Karlovi ć Source Type: research

Erector spinae plane block and placement of perineural catheter for developmental hip disorder surgery in children
We report on a case of effective intraoperative analgesia achieved by ultrasound-guided lumbar ESP block and another case of effective intra- and postoperative analgesia accomplished with perineural catheter placement in addition to lumbar ESP block, both performed in children surgically treated for developmental hip disorders.PMID:34744283 | PMC:PMC8564838 | DOI:10.20471/acc.2021.60.02.19 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Emil Bosinci Svetolik Spasi ć Maja Mitrovi ć Marija Stevi ć Irena Simi ć Du šica Simić Source Type: research

Concurrent deep vein thrombosis and pulmonary embolism associated with hyperthyroidism: a case report
We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.PMID:34744284 | PMC:PMC8564842 | DOI:10.20471/acc.2021.60.02.20 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Josip Kati ć Ana Kati ć Karla Kati ć Darko Duplan čić Mislav Lozo Source Type: research

Spontaneous resolution of a nonfunctioning pituitary adenoma over one-month period: a case report
Acta Clin Croat. 2021 Jun;60(2):317-322. doi: 10.20471/acc.2021.60.02.21.ABSTRACTSpontaneous resolution of nonfunctioning pituitary adenoma after hemorrhagic apoplexy is a rare clinical entity of unknown etiology and is defined as disappearance of a tumor without any specific treatment. Here we present a 54-year-old male patient who presented with acute onset of severe headache, vomiting, photophobia, and sonophobia. He was referred to brain computed tomography, which showed a 16x12x16 mm tumor mass located in the sellar region with signs of hemorrhage. Endocrinologic evaluation was consistent with under-function of pituit...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Luka Komi ć Ivan Kruljac Gorana Miro šević Petar Ga ćina Hrvoje Ivan Pe ćina Vatroslav Čerina Domagoj Gajski Kristina Blaslov Kre šimir Rotim Milan Vrkljan Source Type: research

Benign multicystic peritoneal mesothelioma mimicking gynecologic pathology
We report a case of a a 21-year-old female patient who presented with unclear diffuse abdominal pain. Transvaginal ultrasound and magnetic resonance imaging of the abdomen and pelvis revealed multiple functional cysts in the projection of the right and left ovary and free fluid in the pouch of Douglas. Laparoscopy was performed and multicystic tumor with thin, smooth walls, filled with clear serous content was found in lesser pelvis spreading to the left paracolic region and under the spleen. The multicystic mass was removed. Histologic examination revealed cystic formations filled with mucous content and formed from conne...
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Ilija Alvir Boris Bevanda Damir Danoli ć Ivica Mami ć Lucija Kosti ć Angelina Star čević-Božović Mario Puljiz Source Type: research

Atypical mri findings in cerebral adrenoleukodystrophy: a case report
We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral symmetric frontal lobe white matter changes suggesting anterior predominance.PMID:34744287 | PMC:PMC8564837 | DOI:10.20471/acc.2021.60.02.23 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Koray Ko ç Arzu Canan P ınar Koç Kamil Karaali Özgür Duman Utku Şenol Source Type: research

Ureteral triplication accidentally found during cervical carcinoma operation
We report a case of a 38-year-old female patient diagnosed with cervical carcinoma, where ureteral triplication was detected incidentally during a radical operative procedure.PMID:34744288 | PMC:PMC8564831 | DOI:10.20471/acc.2021.60.02.24 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - November 8, 2021 Category: General Medicine Authors: Dra žan Butorac Ivka Djakovi ć Jasminka Mal čić Ljubomir Jokanovi ć Source Type: research