Combined treatment with bevacizumab and triamcinolone acetonide for macular edema due to retinal vein occlusion
In conclusion, combined treatment with bevacizumab and triamcinolone for the treatment of retinal vein occlusion is more potent, safe, efficient and cost-effective. It can also be recommended because fewer injections are needed in patients undergoing treatment for macular edema.PMID:34285426 | PMC:PMC8253081 | DOI:10.20471/acc.2020.59.04.01 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Maja Vinkovi ć Damir Bosnar Eugenia Tedeschi Reiner Gabriella De Salvo Suzana Mati ć Source Type: research

What can we actually see using computer aided detection in mammography?
In this study, we confirmed CAD as an excellent tool for recognizing microcalcifications with 100% sensitivity. However, it should not be used as a stand-alone tool in breast screening mammography due to the high rate of false-positive results.PMID:34285427 | PMC:PMC8253062 | DOI:10.20471/acc.2020.59.04.02 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Martina D žoić Dominković Gordana Ivanac Niko Radovi ć Mislav Čavka Source Type: research

Prenatal identification of aberrant right subclavian artery in isolation: the need for further genetic work-up?
The objective of this study was to evaluate the association between aberrant right subclavian artery (ARSA) and chromosomal abnormalities. The study included 5211 women having attended our unit for fetal anatomic screening and fetal echocardiography from August 2016 until February 2019. After diagnosing ARSA, prenatal invasive testing was discussed with the patients. ARSA affected fetus was determined in 57 cases; of these, there were 38 cases of isolated ARSA and 19 cases of non-isolated ARSA but associated with soft markers and fetal anomalies. Nineteen patients underwent amniocentesis; Down syndrome was determined in tw...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Reyhan Ayaz Emine G öktas Gurcan Turkyilmaz Mehmet Resit Asoglu Source Type: research

The impact of antiepileptic treatment in pregnancy on perinatal outcome in croatia - a single-center study
Acta Clin Croat. 2020 Dec;59(4):590-596. doi: 10.20471/acc.2020.59.04.04.ABSTRACTPregnancy can alter the natural course of epilepsy and affect pharmacokinetic profile of antiepileptic drugs (AEDs) making therapeutic management more demanding. Since there is no relevant population-based study in Croatia to date, we conducted this research with the aim to observe antiepileptic treatment policy in pregnancy and to determine if the number of AEDs affects pregnancy outcomes. The study included all women with epilepsy with singleton pregnancy exposed to one or more AEDs divided into two groups (group 1: one AED and group 2: more...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Vesna Elve đi-Gašparović Mislav Miku š Petrana Beljan Marta Živković Klara Živković Luka Matak Source Type: research

Effect of preoperative respiratory rehabilitation in patients undergoing cardiac surgery
Acta Clin Croat. 2020 Dec;59(4):597-604. doi: 10.20471/acc.2020.59.04.05.ABSTRACTThe aim of the study was to evaluate the effects of preoperative respiratory rehabilitation on functional capacity, length of stay in intensive care unit (ICU), duration of mechanical ventilation (MV) and total hospitalization, as well as to estimate arterial blood gas (ABG) values in patients undergoing cardiac surgery. Nineteen patients were included in the randomized observational study, divided into two groups: group A (intervention) and B (control). Preoperative and postoperative rehabilitation was performed in group A, and only postopera...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sonja Nejkov Vesna Bokan-Mirkovi ć Nata ša Đukić-Macut Marina Vukovi ć Source Type: research

Factors associated with depression in patients with schizophrenia
Acta Clin Croat. 2020 Dec;59(4):605-614. doi: 10.20471/acc.2020.59.04.06.ABSTRACTThe aim of this study was to analyze risk factors present in schizophrenic patients with depressive symptomatology. The sample comprised of 76 respondents diagnosed with schizophrenia. In the study, we used the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia. The prevalence of depression was estimated to be 30%. The mean scores on the negative subscale of the PANSS were significantly higher in patients with schizophrenia and depression compared to control group (U=3.64, p=0.00), and so were those on ...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Boris Golubovi ć Zoran Gaji ć Olga Iveti ć Jovan Milatovi ć Petar Vulekovi ć Đula Đilvesi Sonja Golubovi ć Filip Vrban Ante Suba šić Lukas Rasuli ć Source Type: research

The influence of periodontal disease treatment on 8-hydroxy-deoxyguanosine concentrations in saliva and plasma of chronic periodontitis patients
Acta Clin Croat. 2020 Dec;59(4):615-622. doi: 10.20471/acc.2020.59.04.07.ABSTRACTThe 8-hydroxy-deoxyguanosine (8-OHdG) is one of the customary products of oxidized DNA. The purpose of this study was to compare salivary and plasma 8-OHdG concentrations in a group of chronic periodontitis patients to those measured in a group of patients with healthy periodontium, as well as to determine the impact of periodontal therapy on 8-OHdG concentrations in saliva and plasma in chronic periodontitis patients. The study sample comprised of 24 patients with chronic periodontitis and 16 periodontally healthy individuals. Plaque index, g...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Tanja Veljovi ć Milanko Đurić Ivana Gu šić Jelena Mirni ć Sa ša Čakić Aleksandra Maletin Sne žana Brkić Source Type: research

Health-related quality of life in primary open-angle glaucoma patients
Acta Clin Croat. 2020 Dec;59(4):623-631. doi: 10.20471/acc.2020.59.04.08.ABSTRACTThe purpose of this research was to evaluate the relationship between general health-related quality of life (GHRQL) and sociodemographic factors in primary open-angle glaucoma (POAG) patients. A prospective cross-sectional study included 207 glaucoma patients. GHRQL was determined via two self-administered questionnaires: the 36-Item Short Form Survey (SF-36) and the EuroQol-5D (EQ-5D) questionnaire. Male and 50- to 69-year-old glaucoma patients, followed by patients who regularly used antiglaucoma therapy and those without progression of gla...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Irena Sesar Anita Pu šić-Sesar Darija Juri šić Antonio Sesar Ivan Merd žo Ivan Ćavar Source Type: research

Nutritional risk screening in gastroenterological patients at the rijeka university hospital centre
Acta Clin Croat. 2020 Dec;59(4):632-640. doi: 10.20471/acc.2020.59.04.09.ABSTRACTMalnutrition is usually related to some diseases such as inflammatory bowel disease, chronic pancreatitis, chronic liver disease and malignant tumors. It is characterized by weight loss, protein deficiency, and deficit of specific nutrients. The aim was to estimate the prevalence of nutritional risk among 160 gastrointestinal patients by use of the Nutritional Risk Screening (NRS-2002) score at hospital admission and discharge. The patients stayed in the hospital between 5 and 15 days or longer. Results showed that 40% of patients at admission...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sandra Pavi čić Žeželj Danijela Malec Dolores Janko-Labinac Tamara Šoić Vranić Gordana Mi četić Balog Tea Schnurrer-Luke-Vrbani ć Tea Čaljkušić Mance Damir Kova čević Olga Cvijanovi ć Peloza Source Type: research

Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an observational study of treatment patterns and lipid control
Acta Clin Croat. 2020 Dec;59(4):641-649. doi: 10.20471/acc.2020.59.04.10.ABSTRACTOur observational study evaluated current management of elevated low-density lipoprotein cholesterol (LDL-C) in adult secondary prevention patients (all very high risk (VHR) by European guidelines) attending specialist clinics across Croatia. Data were collected retrospectively from patient records for the preceding 12 months. The subset judged to be at extreme risk (ER; American Association of Clinical Endocrinologists (AACE) criteria; n=48) were compared with the remaining patients (VHR group; n=41). All patients were receiving statins (75.6...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Hrvoje Pintari ć Marijana Knezovi ć Florijan Ian Bridges Robert Steiner Luka Zaputovi ć Davor Mili čić Source Type: research

Can complete blood cell count parameters predict deep vein thrombosis?
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kevser Tural Fatih Kara Sema Avc ı Halil İbrahim Erdoğdu Source Type: research

The croatian health insurance fund does not recognize differences in the cost of different treatments for revision total hip arthroplasty
Acta Clin Croat. 2020 Dec;59(4):667-671. doi: 10.20471/acc.2020.59.04.13.ABSTRACTIn recent years, there has been increased interest in the cost of treatment for revision interventions for hip and knee prostheses. In all publications so far, the authors note the high cost of treatment for revision interventions, especially if infection is present. The aim of this study was to compare the cost of treatment and health insurance reimbursements between revision total hip arthroplasty (THA) for infection and revision for aseptic indications (aseptic instability and periprosthetic fracture). Hospital data on 168 patients having u...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sre ćko Sabalić Dinko Vidovi ć Slaven Babi ć Tomislav Ćuti Domagoj Gajski Kre šimir Rotim Dejan Bla žević Source Type: research

Anthropometric measurements, dietary habits, serum lipid and glucose levels in relation to high blood pressure among adolescent boys and girls in croatia
Acta Clin Croat. 2020 Dec;59(4):672-685. doi: 10.20471/acc.2020.59.04.14.ABSTRACTThe aim was to determine differences in anthropometric measurements, dietary habits, serum lipid and glucose levels in relation to high blood pressure (BP) among adolescent boys and girls in Croatia. The specific aim was to determine the effect of dietary habits and lifestyle on high BP in adolescents according to sex. The study included 260 (68.2%) adolescent girls and 121 (31.8%) boys with anthropometric data obtained (without missing values) from 246 girls and 111 boys. Participants answered questions from the questionnaire and anthropometr...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Olgica Martinis Miran Čoklo Jasna Aladrovi ć Anja Belavi ć Sa ša Missoni Source Type: research

Treatment of pediatric femoral fractures in the city of zagreb
In conclusion, nearly half of all femur fractures (49.1%) occurred at a young age (0-4 years). Diaphysis fractures were most common. Most of the fractures that occurred during the 2010-2015 period were treated with operative methods, mostly in children aged 5-9 years. Out of eight different operative methods, elastic stable intramedullary osteosynthesis was most frequently used (60%). Coxofemoral immobilization and traction were used as non-operative methods.PMID:34285439 | PMC:PMC8253082 | DOI:10.20471/acc.2020.59.04.15 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Anko Antabak Nikolina Bor šćak Marija Čagalj Renato Ivelj Igor Bum či Dino Pape š Stanko Ćavar Marko Bogovi ć Kre šimir Bulić Tomislav Lueti ć Source Type: research

The association of subclinical insulin resistance with thyroid autoimmunity in euthyroid individuals
Acta Clin Croat. 2020 Dec;59(4):696-702. doi: 10.20471/acc.2020.59.04.16.ABSTRACTHashimoto thyroiditis is characterized by anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin (anti-Tg) antibodies that gradually lead to thyroid cell destruction. As hypothyroidism has been associated with insulin resistance (IR), we aimed to investigate whether IR is associated with thyroid antibody presence and whether the degree of IR correlates with their concentration in euthyroid individuals. A total of 164 non-diabetic, euthyroid individuals, average age 34 years, were included in the study, divided into two groups according to H...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kristina Blaslov Domagoj Gajski Vesna Vuceli ć Petar Ga ćina Gorana Miro šević Jelena Marinkovi ć Milan Vrkljan Kre šimir Rotim Source Type: research

Correlation between the level of colorectal anastomosis and anorectal function
Acta Clin Croat. 2020 Dec;59(4):703-711. doi: 10.20471/acc.2020.59.04.17.ABSTRACTAnterior rectal resection is a standard surgical procedure for treating carcinomas of rectum and distal sigmoid colon. In many cases of anterior rectal resection, postoperatively some level of fecal incontinence may occur. The aim of our study was to evaluate the impact of the colorectal anastomosis level on anorectal functional disorder. In our prospective study, the participants were patients diagnosed with carcinoma of rectum or distal sigmoid colon. All patients underwent standard open or laparoscopic anterior rectal resection. Six months ...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Branko Bakula Žarko Rašić Dragan Jur čić Marko Lucijani ć Fran Ra šić Source Type: research

Endovascular management of intracranial aneurysms on distal arterial branches: illustrative case series and literature retrospection
In conclusion, due to their predisposition for rupture, distal branch intracranial aneurysms should be treated early and aggressively. We do believe that endovascular selective coil occlusion is the management method of choice, while parent vessel occlusion (with liquid embolics) is optimal when aneurysmal coiling cannot be achieved, or when distal cortical territory is well vascularized by strong collateral cerebral circulation.PMID:34285442 | PMC:PMC8253063 | DOI:10.20471/acc.2020.59.04.18 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kre šimir Rotim Bruno Splavski Vladimir Kalousek Mia Jurilj Tomislav Sajko Source Type: research

Triple model of auditory sensory processing: a novel gating stream directly links primary auditory areas to executive prefrontal cortex
Acta Clin Croat. 2020 Dec;59(4):721-728. doi: 10.20471/acc.2020.59.04.19.ABSTRACTThe generally accepted model of sensory processing of visual and auditory stimuli assumes two major parallel processing streams, ventral and dorsal, which comprise functionally and anatomically distinct but interacting processes in which the ventral stream supports stimulus identification, and the dorsal stream is involved in recognizing the stimulus spatial location and sensori-motor integration functions. However, recent studies suggest the existence of a third, very fast sensory processing pathway, a gating stream that directly links the pr...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sanja Josef-Golubi ć Source Type: research

The use of electroretinography and optical coherence tomography in patients with schizophrenia
Acta Clin Croat. 2020 Dec;59(4):729-739. doi: 10.20471/acc.2020.59.04.20.ABSTRACTThe use of electroretinography (ERG) and optical coherence tomography (OCT) has currently expanded beyond ophthalmology alone. The aim of this review is to present the results and knowledge acquired by these two methods in patients suffering from schizophrenia. Reviewing the studies applying ERG and OCT methods in the field of psychiatry, one can conclude that results of the research imply morphological and functional changes of retina in patients with schizophrenia that are not consistent. However, in most studies there was reduction of the a...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Din Durakovi ć Ante Sili ć Vjekoslav Peitl Ra šeljka Tadić Kristina Lon čarić Trpimir Glavina Daniela Šago Ljiljana Pa čić Turk Dalibor Karlovi ć Source Type: research

Could covid-19 be a hemoglobinopathy?
Acta Clin Croat. 2020 Dec;59(4):740-744. doi: 10.20471/acc.2020.59.04.21.ABSTRACTThe world is struggling to deal with the corona pandemic. Effective therapies are still awaited due to the lack of understanding of the pathophysiological mechanism of the disease. Bearing recent research and clinical observations in mind, the authors propose a novel physiological mechanism of COVID-19 and explain development of COVID-19 related acute respiratory distress syndrome (ARDS) secondary to COVID-19 related hemoglobinopathy. It is a consistent observation that the radiological picture of COVID-19 related ARDS bears more resemblance t...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Tania Ahmed Shakoori Muhammad Mansoor Hafeez Arif Malik Source Type: research

TREATMENT OF < em > VERRUCA VULGARIS < /em > IN TRADITIONAL MEDICINE
Acta Clin Croat. 2020 Dec;59(4):745-750. doi: 10.20471/acc.2020.59.04.22.ABSTRACTCommon warts (verrucae vulgares) are the most common complaint in routine dermatological practice. Warts can be painful on pressure and are often an aesthetic problem, but they are not a major threat to the person's general health. Treatment options are symptomatic and do not eradicate the causative agent. Dermatological surgery procedures such as cryotherapy, electrocauterization and excochleation can be painful, with common recurrences. These are the most important reasons for revival of the treatment procedures and remedies based on traditi...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Ivanka Mur šić Aleksandar V čev Lena Kotrulja Igor Kuric Tina Milavi ć Nela Šustić Maja Tolu šić Levak Source Type: research

URINARY STONE RELATED URINARY TRACT INFECTION CAUSED BY < em > RAOULTELLA ORNITHINOLYTICA < /em > IN A CHILD: A CASE REPORT
Acta Clin Croat. 2020 Dec;59(4):751-753. doi: 10.20471/acc.2020.59.04.23.ABSTRACTRaoultella ornithinolytica is one of the three species of Raoultella. The present case report describes a two-year-old child who had complaints of discomfort and fever, and Raoultella ornithinolytica in his urinary culture. Grade-2 hydronephrosis and a 7.5-mm urinary stone were detected in the patient's left ureter. The stone was expelled upon consultation with pediatric urology department. The patient was treated according to culture antibiotic sensitivity report and continued to be followed-up.PMID:34285447 | PMC:PMC8253079 | DOI:10.20471/ac...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Mehmet Karac ı Adem Ya şar Source Type: research

Current endovascular management of infected distal branch intracranial aneurysms: a case report and insight into the literature
In conclusion, selective endovascular coiling is a preferable method in the current management of distal branch infected ruptured intracranial aneurysms, which may bring a favorable outcome.PMID:34285448 | PMC:PMC8253077 | DOI:10.20471/acc.2020.59.04.24 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Vladimir Kalousek Tomislav Sajko Bruno Splavski Kre šimir Rotim Mia Jurilj Branimir Čulo Ante Rotim Source Type: research

Oxaliplatin induced pulmonary fibrosis: a case report
Acta Clin Croat. 2020 Dec;59(4):761-764. doi: 10.20471/acc.2020.59.04.25.ABSTRACTOxaliplatin is part of the standard chemotherapy regimens for treating colorectal carcinoma. Pulmonary fibrosis is a serious but rare side effect of oxaliplatin treatment, which resulted in patient death in more than half of the reported cases. The precise pathophysiological mechanism of this phenomenon has not been clarified yet. Analysis of the reported cases strongly suggests that early diagnosis and immediate corticosteroid treatment are crucial for better prognosis. Here we report a case of pulmonary fibrosis related to the FOLFOX regimen...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Mirjana Pavlovi ć Robert Šeparović Tajana Silovski Ana Te čić Vuger Andreja Juri ć Source Type: research

Morphea and lichen sclerosus in a patient with hyporthyroidism
Acta Clin Croat. 2020 Dec;59(4):765-770. doi: 10.20471/acc.2020.59.04.26.ABSTRACTThyroid gland is one of the key organs regulating the metabolism of carbohydrates, proteins and fats. Its primary function is connected with increase of the metabolic conversion of the body. Skin lesions are often one of the first symptoms of hypothyroidism. In a 71-year-old patient, skin lesions in the form of thickened areas with severe hyperkeratosis first appeared 12 years before. Eight years before, the patient was diagnosed with hypothyroidism of unknown cause. Upon admission, lesions were observed in the trunk area, left arm and vulva. ...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Beata Bergler-Czop Ligia Brzezi ńska-Wcisło Source Type: research

The enigma of lewy body dementia: a case report
Acta Clin Croat. 2020 Dec;59(4):771-776. doi: 10.20471/acc.2020.59.04.27.ABSTRACTLewy body dementia is a progressive neurodegenerative disease and is considered to be the second most common cause of dementia in the elderly. Because of the complexity of clinical presentation, it is often misdiagnosed and mistaken for other dementias, which may result in administering inappropriate therapy, and thus worsening of the patient condition. We reviewed a case of a 71-year-old patient whose clinical presentation gradually occurred with complex visual hallucinations, atypical extrapyramidal motor symptoms, fluctuating cognitive impa...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Ivona Orlovi ć Matija Bartolovi ć Katarina Maru šić Darko Vlahovi ć Ines Šiško Markoš Dalibor Karlovi ć Vjekoslav Peitl Source Type: research

Combined treatment with bevacizumab and triamcinolone acetonide for macular edema due to retinal vein occlusion
In conclusion, combined treatment with bevacizumab and triamcinolone for the treatment of retinal vein occlusion is more potent, safe, efficient and cost-effective. It can also be recommended because fewer injections are needed in patients undergoing treatment for macular edema.PMID:34285426 | PMC:PMC8253081 | DOI:10.20471/acc.2020.59.04.01 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Maja Vinkovi ć Damir Bosnar Eugenia Tedeschi Reiner Gabriella De Salvo Suzana Mati ć Source Type: research

What can we actually see using computer aided detection in mammography?
In this study, we confirmed CAD as an excellent tool for recognizing microcalcifications with 100% sensitivity. However, it should not be used as a stand-alone tool in breast screening mammography due to the high rate of false-positive results.PMID:34285427 | PMC:PMC8253062 | DOI:10.20471/acc.2020.59.04.02 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Martina D žoić Dominković Gordana Ivanac Niko Radovi ć Mislav Čavka Source Type: research

Prenatal identification of aberrant right subclavian artery in isolation: the need for further genetic work-up?
The objective of this study was to evaluate the association between aberrant right subclavian artery (ARSA) and chromosomal abnormalities. The study included 5211 women having attended our unit for fetal anatomic screening and fetal echocardiography from August 2016 until February 2019. After diagnosing ARSA, prenatal invasive testing was discussed with the patients. ARSA affected fetus was determined in 57 cases; of these, there were 38 cases of isolated ARSA and 19 cases of non-isolated ARSA but associated with soft markers and fetal anomalies. Nineteen patients underwent amniocentesis; Down syndrome was determined in tw...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Reyhan Ayaz Emine G öktas Gurcan Turkyilmaz Mehmet Resit Asoglu Source Type: research

The impact of antiepileptic treatment in pregnancy on perinatal outcome in croatia - a single-center study
Acta Clin Croat. 2020 Dec;59(4):590-596. doi: 10.20471/acc.2020.59.04.04.ABSTRACTPregnancy can alter the natural course of epilepsy and affect pharmacokinetic profile of antiepileptic drugs (AEDs) making therapeutic management more demanding. Since there is no relevant population-based study in Croatia to date, we conducted this research with the aim to observe antiepileptic treatment policy in pregnancy and to determine if the number of AEDs affects pregnancy outcomes. The study included all women with epilepsy with singleton pregnancy exposed to one or more AEDs divided into two groups (group 1: one AED and group 2: more...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Vesna Elve đi-Gašparović Mislav Miku š Petrana Beljan Marta Živković Klara Živković Luka Matak Source Type: research

Effect of preoperative respiratory rehabilitation in patients undergoing cardiac surgery
Acta Clin Croat. 2020 Dec;59(4):597-604. doi: 10.20471/acc.2020.59.04.05.ABSTRACTThe aim of the study was to evaluate the effects of preoperative respiratory rehabilitation on functional capacity, length of stay in intensive care unit (ICU), duration of mechanical ventilation (MV) and total hospitalization, as well as to estimate arterial blood gas (ABG) values in patients undergoing cardiac surgery. Nineteen patients were included in the randomized observational study, divided into two groups: group A (intervention) and B (control). Preoperative and postoperative rehabilitation was performed in group A, and only postopera...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sonja Nejkov Vesna Bokan-Mirkovi ć Nata ša Đukić-Macut Marina Vukovi ć Source Type: research

Factors associated with depression in patients with schizophrenia
Acta Clin Croat. 2020 Dec;59(4):605-614. doi: 10.20471/acc.2020.59.04.06.ABSTRACTThe aim of this study was to analyze risk factors present in schizophrenic patients with depressive symptomatology. The sample comprised of 76 respondents diagnosed with schizophrenia. In the study, we used the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia. The prevalence of depression was estimated to be 30%. The mean scores on the negative subscale of the PANSS were significantly higher in patients with schizophrenia and depression compared to control group (U=3.64, p=0.00), and so were those on ...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Boris Golubovi ć Zoran Gaji ć Olga Iveti ć Jovan Milatovi ć Petar Vulekovi ć Đula Đilvesi Sonja Golubovi ć Filip Vrban Ante Suba šić Lukas Rasuli ć Source Type: research

The influence of periodontal disease treatment on 8-hydroxy-deoxyguanosine concentrations in saliva and plasma of chronic periodontitis patients
Acta Clin Croat. 2020 Dec;59(4):615-622. doi: 10.20471/acc.2020.59.04.07.ABSTRACTThe 8-hydroxy-deoxyguanosine (8-OHdG) is one of the customary products of oxidized DNA. The purpose of this study was to compare salivary and plasma 8-OHdG concentrations in a group of chronic periodontitis patients to those measured in a group of patients with healthy periodontium, as well as to determine the impact of periodontal therapy on 8-OHdG concentrations in saliva and plasma in chronic periodontitis patients. The study sample comprised of 24 patients with chronic periodontitis and 16 periodontally healthy individuals. Plaque index, g...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Tanja Veljovi ć Milanko Đurić Ivana Gu šić Jelena Mirni ć Sa ša Čakić Aleksandra Maletin Sne žana Brkić Source Type: research

Health-related quality of life in primary open-angle glaucoma patients
Acta Clin Croat. 2020 Dec;59(4):623-631. doi: 10.20471/acc.2020.59.04.08.ABSTRACTThe purpose of this research was to evaluate the relationship between general health-related quality of life (GHRQL) and sociodemographic factors in primary open-angle glaucoma (POAG) patients. A prospective cross-sectional study included 207 glaucoma patients. GHRQL was determined via two self-administered questionnaires: the 36-Item Short Form Survey (SF-36) and the EuroQol-5D (EQ-5D) questionnaire. Male and 50- to 69-year-old glaucoma patients, followed by patients who regularly used antiglaucoma therapy and those without progression of gla...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Irena Sesar Anita Pu šić-Sesar Darija Juri šić Antonio Sesar Ivan Merd žo Ivan Ćavar Source Type: research

Nutritional risk screening in gastroenterological patients at the rijeka university hospital centre
Acta Clin Croat. 2020 Dec;59(4):632-640. doi: 10.20471/acc.2020.59.04.09.ABSTRACTMalnutrition is usually related to some diseases such as inflammatory bowel disease, chronic pancreatitis, chronic liver disease and malignant tumors. It is characterized by weight loss, protein deficiency, and deficit of specific nutrients. The aim was to estimate the prevalence of nutritional risk among 160 gastrointestinal patients by use of the Nutritional Risk Screening (NRS-2002) score at hospital admission and discharge. The patients stayed in the hospital between 5 and 15 days or longer. Results showed that 40% of patients at admission...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sandra Pavi čić Žeželj Danijela Malec Dolores Janko-Labinac Tamara Šoić Vranić Gordana Mi četić Balog Tea Schnurrer-Luke-Vrbani ć Tea Čaljkušić Mance Damir Kova čević Olga Cvijanovi ć Peloza Source Type: research

Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an observational study of treatment patterns and lipid control
Acta Clin Croat. 2020 Dec;59(4):641-649. doi: 10.20471/acc.2020.59.04.10.ABSTRACTOur observational study evaluated current management of elevated low-density lipoprotein cholesterol (LDL-C) in adult secondary prevention patients (all very high risk (VHR) by European guidelines) attending specialist clinics across Croatia. Data were collected retrospectively from patient records for the preceding 12 months. The subset judged to be at extreme risk (ER; American Association of Clinical Endocrinologists (AACE) criteria; n=48) were compared with the remaining patients (VHR group; n=41). All patients were receiving statins (75.6...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Hrvoje Pintari ć Marijana Knezovi ć Florijan Ian Bridges Robert Steiner Luka Zaputovi ć Davor Mili čić Source Type: research

Can complete blood cell count parameters predict deep vein thrombosis?
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kevser Tural Fatih Kara Sema Avc ı Halil İbrahim Erdoğdu Source Type: research

The croatian health insurance fund does not recognize differences in the cost of different treatments for revision total hip arthroplasty
Acta Clin Croat. 2020 Dec;59(4):667-671. doi: 10.20471/acc.2020.59.04.13.ABSTRACTIn recent years, there has been increased interest in the cost of treatment for revision interventions for hip and knee prostheses. In all publications so far, the authors note the high cost of treatment for revision interventions, especially if infection is present. The aim of this study was to compare the cost of treatment and health insurance reimbursements between revision total hip arthroplasty (THA) for infection and revision for aseptic indications (aseptic instability and periprosthetic fracture). Hospital data on 168 patients having u...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sre ćko Sabalić Dinko Vidovi ć Slaven Babi ć Tomislav Ćuti Domagoj Gajski Kre šimir Rotim Dejan Bla žević Source Type: research

Anthropometric measurements, dietary habits, serum lipid and glucose levels in relation to high blood pressure among adolescent boys and girls in croatia
Acta Clin Croat. 2020 Dec;59(4):672-685. doi: 10.20471/acc.2020.59.04.14.ABSTRACTThe aim was to determine differences in anthropometric measurements, dietary habits, serum lipid and glucose levels in relation to high blood pressure (BP) among adolescent boys and girls in Croatia. The specific aim was to determine the effect of dietary habits and lifestyle on high BP in adolescents according to sex. The study included 260 (68.2%) adolescent girls and 121 (31.8%) boys with anthropometric data obtained (without missing values) from 246 girls and 111 boys. Participants answered questions from the questionnaire and anthropometr...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Olgica Martinis Miran Čoklo Jasna Aladrovi ć Anja Belavi ć Sa ša Missoni Source Type: research

Treatment of pediatric femoral fractures in the city of zagreb
In conclusion, nearly half of all femur fractures (49.1%) occurred at a young age (0-4 years). Diaphysis fractures were most common. Most of the fractures that occurred during the 2010-2015 period were treated with operative methods, mostly in children aged 5-9 years. Out of eight different operative methods, elastic stable intramedullary osteosynthesis was most frequently used (60%). Coxofemoral immobilization and traction were used as non-operative methods.PMID:34285439 | PMC:PMC8253082 | DOI:10.20471/acc.2020.59.04.15 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Anko Antabak Nikolina Bor šćak Marija Čagalj Renato Ivelj Igor Bum či Dino Pape š Stanko Ćavar Marko Bogovi ć Kre šimir Bulić Tomislav Lueti ć Source Type: research

The association of subclinical insulin resistance with thyroid autoimmunity in euthyroid individuals
Acta Clin Croat. 2020 Dec;59(4):696-702. doi: 10.20471/acc.2020.59.04.16.ABSTRACTHashimoto thyroiditis is characterized by anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin (anti-Tg) antibodies that gradually lead to thyroid cell destruction. As hypothyroidism has been associated with insulin resistance (IR), we aimed to investigate whether IR is associated with thyroid antibody presence and whether the degree of IR correlates with their concentration in euthyroid individuals. A total of 164 non-diabetic, euthyroid individuals, average age 34 years, were included in the study, divided into two groups according to H...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kristina Blaslov Domagoj Gajski Vesna Vuceli ć Petar Ga ćina Gorana Miro šević Jelena Marinkovi ć Milan Vrkljan Kre šimir Rotim Source Type: research

Correlation between the level of colorectal anastomosis and anorectal function
Acta Clin Croat. 2020 Dec;59(4):703-711. doi: 10.20471/acc.2020.59.04.17.ABSTRACTAnterior rectal resection is a standard surgical procedure for treating carcinomas of rectum and distal sigmoid colon. In many cases of anterior rectal resection, postoperatively some level of fecal incontinence may occur. The aim of our study was to evaluate the impact of the colorectal anastomosis level on anorectal functional disorder. In our prospective study, the participants were patients diagnosed with carcinoma of rectum or distal sigmoid colon. All patients underwent standard open or laparoscopic anterior rectal resection. Six months ...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Branko Bakula Žarko Rašić Dragan Jur čić Marko Lucijani ć Fran Ra šić Source Type: research

Endovascular management of intracranial aneurysms on distal arterial branches: illustrative case series and literature retrospection
In conclusion, due to their predisposition for rupture, distal branch intracranial aneurysms should be treated early and aggressively. We do believe that endovascular selective coil occlusion is the management method of choice, while parent vessel occlusion (with liquid embolics) is optimal when aneurysmal coiling cannot be achieved, or when distal cortical territory is well vascularized by strong collateral cerebral circulation.PMID:34285442 | PMC:PMC8253063 | DOI:10.20471/acc.2020.59.04.18 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Kre šimir Rotim Bruno Splavski Vladimir Kalousek Mia Jurilj Tomislav Sajko Source Type: research

Triple model of auditory sensory processing: a novel gating stream directly links primary auditory areas to executive prefrontal cortex
Acta Clin Croat. 2020 Dec;59(4):721-728. doi: 10.20471/acc.2020.59.04.19.ABSTRACTThe generally accepted model of sensory processing of visual and auditory stimuli assumes two major parallel processing streams, ventral and dorsal, which comprise functionally and anatomically distinct but interacting processes in which the ventral stream supports stimulus identification, and the dorsal stream is involved in recognizing the stimulus spatial location and sensori-motor integration functions. However, recent studies suggest the existence of a third, very fast sensory processing pathway, a gating stream that directly links the pr...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Sanja Josef-Golubi ć Source Type: research

The use of electroretinography and optical coherence tomography in patients with schizophrenia
Acta Clin Croat. 2020 Dec;59(4):729-739. doi: 10.20471/acc.2020.59.04.20.ABSTRACTThe use of electroretinography (ERG) and optical coherence tomography (OCT) has currently expanded beyond ophthalmology alone. The aim of this review is to present the results and knowledge acquired by these two methods in patients suffering from schizophrenia. Reviewing the studies applying ERG and OCT methods in the field of psychiatry, one can conclude that results of the research imply morphological and functional changes of retina in patients with schizophrenia that are not consistent. However, in most studies there was reduction of the a...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Din Durakovi ć Ante Sili ć Vjekoslav Peitl Ra šeljka Tadić Kristina Lon čarić Trpimir Glavina Daniela Šago Ljiljana Pa čić Turk Dalibor Karlovi ć Source Type: research

Could covid-19 be a hemoglobinopathy?
Acta Clin Croat. 2020 Dec;59(4):740-744. doi: 10.20471/acc.2020.59.04.21.ABSTRACTThe world is struggling to deal with the corona pandemic. Effective therapies are still awaited due to the lack of understanding of the pathophysiological mechanism of the disease. Bearing recent research and clinical observations in mind, the authors propose a novel physiological mechanism of COVID-19 and explain development of COVID-19 related acute respiratory distress syndrome (ARDS) secondary to COVID-19 related hemoglobinopathy. It is a consistent observation that the radiological picture of COVID-19 related ARDS bears more resemblance t...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Tania Ahmed Shakoori Muhammad Mansoor Hafeez Arif Malik Source Type: research

TREATMENT OF < em > VERRUCA VULGARIS < /em > IN TRADITIONAL MEDICINE
Acta Clin Croat. 2020 Dec;59(4):745-750. doi: 10.20471/acc.2020.59.04.22.ABSTRACTCommon warts (verrucae vulgares) are the most common complaint in routine dermatological practice. Warts can be painful on pressure and are often an aesthetic problem, but they are not a major threat to the person's general health. Treatment options are symptomatic and do not eradicate the causative agent. Dermatological surgery procedures such as cryotherapy, electrocauterization and excochleation can be painful, with common recurrences. These are the most important reasons for revival of the treatment procedures and remedies based on traditi...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Ivanka Mur šić Aleksandar V čev Lena Kotrulja Igor Kuric Tina Milavi ć Nela Šustić Maja Tolu šić Levak Source Type: research

URINARY STONE RELATED URINARY TRACT INFECTION CAUSED BY < em > RAOULTELLA ORNITHINOLYTICA < /em > IN A CHILD: A CASE REPORT
Acta Clin Croat. 2020 Dec;59(4):751-753. doi: 10.20471/acc.2020.59.04.23.ABSTRACTRaoultella ornithinolytica is one of the three species of Raoultella. The present case report describes a two-year-old child who had complaints of discomfort and fever, and Raoultella ornithinolytica in his urinary culture. Grade-2 hydronephrosis and a 7.5-mm urinary stone were detected in the patient's left ureter. The stone was expelled upon consultation with pediatric urology department. The patient was treated according to culture antibiotic sensitivity report and continued to be followed-up.PMID:34285447 | PMC:PMC8253079 | DOI:10.20471/ac...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Mehmet Karac ı Adem Ya şar Source Type: research

Current endovascular management of infected distal branch intracranial aneurysms: a case report and insight into the literature
In conclusion, selective endovascular coiling is a preferable method in the current management of distal branch infected ruptured intracranial aneurysms, which may bring a favorable outcome.PMID:34285448 | PMC:PMC8253077 | DOI:10.20471/acc.2020.59.04.24 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Vladimir Kalousek Tomislav Sajko Bruno Splavski Kre šimir Rotim Mia Jurilj Branimir Čulo Ante Rotim Source Type: research

Oxaliplatin induced pulmonary fibrosis: a case report
Acta Clin Croat. 2020 Dec;59(4):761-764. doi: 10.20471/acc.2020.59.04.25.ABSTRACTOxaliplatin is part of the standard chemotherapy regimens for treating colorectal carcinoma. Pulmonary fibrosis is a serious but rare side effect of oxaliplatin treatment, which resulted in patient death in more than half of the reported cases. The precise pathophysiological mechanism of this phenomenon has not been clarified yet. Analysis of the reported cases strongly suggests that early diagnosis and immediate corticosteroid treatment are crucial for better prognosis. Here we report a case of pulmonary fibrosis related to the FOLFOX regimen...
Source: Acta Clinica Croatica - July 21, 2021 Category: General Medicine Authors: Mirjana Pavlovi ć Robert Šeparović Tajana Silovski Ana Te čić Vuger Andreja Juri ć Source Type: research