In vitro studies of phenethyl isothiocyanate against the growth of LN229 human glioma cells.
In this study, we explored the inhibitory effects as well as mechanisms of PEITC on human glioma LN229 cells. Results demonstrated that PEITC possesses the potential ability to inhibit proliferation, induce apoptosis and arrest cell cycling against LN229 human glioma cells. Moreover, investigated results showed that PEITC inhibited the expression of superoxide dismutase (SOD) and glutathione (GSH), and caused oxidative stress to tumor cells. Collective results suggested us to believe that PEITC can inhibit the growth of LN229 cells and its mechanism can be related to the fact that PEITC can cause oxidative stress to tumor ...
Source: Clinical Lung Cancer - June 24, 2015 Category: Cancer & Oncology Authors: Su JC, Lin K, Wang Y, Sui SH, Gao ZY, Wang ZG Tags: Int J Clin Exp Pathol Source Type: research
In vitro growth-inhibitory effect of Brazilian plants extracts against Paenibacillus larvae and toxicity in bees.
Abstract
American foulbrood (AFB) is a serious worldwide spreading disease in bees caused by Paenibacillus larvae. Plants extracts are known to decrease or inhibit the growth of these bacteria. The purpose of this study was to evaluate the antimicrobial activity of Calendula. officinalis, Cariniana domestica, and Nasturtium officinale extracts against the P. larvae and to evaluate the toxicity of the extracts in bees. In vitro activity against P. larvae of the extracts was evaluated by micro dilution method and the minimal inhibitory concentrations (MICs) were also determined. The concentrations used in th...
Source: An Acad Bras Cienc - June 9, 2015 Category: Science Authors: Piana M, Brum TF, Boligon AA, Alves CF, Freitas RB, Nunes LT, Mossmann NJ, Janovik V, Jesus RS, Vaucher RA, Santos RC, Athayde ML Tags: An Acad Bras Cienc Source Type: research
Application of ultrasound and chemical sanitizers to watercress, parsley and strawberry: Microbiological and physicochemical quality
This study aimed to evaluate the effectiveness of the use of ultrasound combined with chemical sanitizers for the decontamination of watercress, parsley and strawberries. Samples were treated with ultrasound (45 kHz) for 10 min in the presence of 20 and 200 mg/L sodium dichloroisocyanurate, 5% hydrogen peroxide, 10 mg/L chlorine dioxide or 40 mg/L peracetic acid. The treatment effects on physicochemical parameters and natural contaminant microbiota were evaluated. Sanitizing watercress with different treatments, such as hydrogen peroxide, chlorine dioxide, ultrasound in association with sodium dichloroisocyanurate, pe...
Source: LWT Food Science and Technology - June 5, 2015 Category: Food Science Source Type: research
The anti-oxidant properties of isothiocyanates: a review.
Authors: de Figueiredo SM, Filho SA, Nogueira-Machado JA, Caligiorne RB
Abstract
Cruciferous vegetables, such as broccoli and watercress, have been studied extensively aiming to evaluate their chemopreventive properties. Some of them have already been established using animal models. The ITCs induce Phase II enzymes related to detoxification processes of chemical carcinogens to prevent the start of carcinogenesis. They also exhibit antitumor activity at post-initiation phase, suggesting their additional role(s) in cancer prevention. Sulforaphane is the most extensively studied isothiocyanate, focused in it...
Source: Recent Patents on Endocrine, Metabolic and Immune Drug Discovery - June 4, 2015 Category: Endocrinology Tags: Recent Pat Endocr Metab Immune Drug Discov Source Type: research
Non-indolyl cruciferous phytoalexins: Nasturlexins and tridentatols, a striking convergent evolution of defenses in terrestrial plants and marine animals?
Publication date: May 2015 Source:Phytochemistry, Volume 113 Author(s): M. Soledade C. Pedras , Q. Huy To Highly specialized chemical defense pathways are a particularly noteworthy metabolic characteristic of sessile organisms, whether terrestrial or marine, providing protection against pests and diseases. For this reason, knowledge of the metabolites involved in these processes is crucial to producing ecologically fit crops. Toward this end, the elicited chemical defenses of the crucifer watercress (Nasturtium officinale R. Br.), i.e. phytoalexins, were investigated and are reported. Almost three decades after publi...
Source: Phytochemistry - May 26, 2015 Category: Chemistry Source Type: research
Suppression of CXCR4 Expression by ITCs
This study demonstrates, for the first time, that cancer chemopreventive ITCs suppress CXCR4 expression in prostate cancer cells in vitro as well as in vivo. These results suggest that CXCR4 downregulation may be an important pharmacodynamic biomarker of cancer chemopreventative ITCs in prostate adenocarcinoma. Cancer Prev Res; 8(5); 365–74. ©2015 AACR. (Source: Cancer Prevention Research)
Source: Cancer Prevention Research - April 30, 2015 Category: Cancer & Oncology Authors: Sakao, K., Vyas, A. R., Chinni, S. R., Amjad, A. I., Parikh, R., Singh, S. V. Tags: Research Articles Source Type: research
Elemental distribution and uptake by watercress (Nasturtium aquaticum) as a function of water quality.
Abstract
Watercress (Nasturtium aquaticum), is an edible plant commonly found in Southern Africa, which grows both in terrestrial and aquatic environments. The elemental concentrations in the plant and surrounding water (growth solution) were investigated to determine the plants nutritional value and to establish impact of water quality on elemental uptake by the plant. The concentrations in the leaves, roots and water were analyzed at eight different sites along the east coast of KwaZulu-Natal, South Africa (30.0000° S, 25.0000° E). Elemental concentrations in the leaves/roots (μg g(-1), dry mass) and ...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - April 8, 2015 Category: Environmental Health Authors: Kisten K, Gounden D, Moodley R, Jonnalagadda SB Tags: J Environ Sci Health B Source Type: research
Parasitic contamination of commonly consumed fresh leafy vegetables in benha, egypt.
This study evaluated the degree of parasitic contamination of vegetables which are commercialized and consumed fresh in Benha, Egypt. It included 530 vegetables: lettuce, watercress, parsley, green onion, and leek. Vegetables were collected randomly from markets within Benha. Samples were washed in saline, and the resulting washing solution was filtered and centrifuged to concentrate the parasitic stages. Sediments and supernatants were examined by iodine and modified Ziehl-Neelsen stained smears. Intestinal parasites were detected in 157/530 (29.6%) samples. Giardia lamblia cysts were the most prevalent parasite (8.8%) fo...
Source: Journal of Parasitology Research - December 1, 2014 Category: Parasitology Tags: J Parasitol Res Source Type: research
Isothiocyanate Synthetic Analogs: Biological Activities, Structure-Activity Relationships and Synthetic Strategies.
Abstract
Sulforaphane is a natural product that is constantly under biological investigation for its unique biological properties (SFN). This naturally occurring isothiocyanate (ITC) and its analogs are the main components of cruciferous vegetables, such as cauliflower, watercress, broccoli, cabbage, Brussels sprouts, widely used as chemopreventive agents. Due to their interesting biological profiles, natural ITCs have been exploited as starting point to develop new synthetic analogs. The present mini-review briefly highlights the most important biological actions of selected new synthetic ITCs focusing on...
Source: Mini Reviews in Medicinal Chemistry - November 6, 2014 Category: Chemistry Authors: Milelli A, Fimognari C, Ticchi N, Neviani P, Minarini A, Tumiatti V Tags: Mini Rev Med Chem Source Type: research
Microbiological quality and safety of minimally processed vegetables marketed in Campinas, SP – Brazil, as assessed by traditional and alternative methods
In conclusion, it has been observed that the microbiological quality of MPV commercialized in Campinas is generally satisfactory. Besides, the choice of microbiological method should be based not only on resource and time issues, but also on parameters such as sensitivity and specificity for the specific foods under analysis. Highlights ► Microbiological evaluation of MPV by traditional and rapid methods. ► Indicator microorganisms, staphylococci, Salmonella and L. monocytogenes analyzed. ► Reveal Salmonella led to high positivity rates than Vidas, 1,2 Test, traditional. ► Vidas, Vip, Reveal, and traditional metho...
Source: Food Control - November 2, 2014 Category: Food Science Source Type: research
Application of watercress (Nasturtium officinale R. Br.) for biotreatment of a textile dye: Investigation of some physiological responses and effects of operational parameters
Publication date: October 2014 Source:Chemical Engineering Research and Design, Volume 92, Issue 10 Author(s): S. Torbati , A.R. Khataee , A. Movafeghi Phytoremediation is an effective and low cost technology to remove different pollutants such as dye containing effluents from the environment. In the present study, the potential of Nasturtium officinale for degradation of C.I. Basic Red 46 (BR46) were investigated. The results revealed the decolorization ability of the plant species up to 87%. The metabolic fate of the dye was proposed by identification of six intermediate compounds produced during this process by G...
Source: Chemical Engineering Research and Design - October 17, 2014 Category: Chemistry Source Type: research
Consumer Acceptability and Sensory Profile of Cooked Broccoli with Mustard Seeds Added to Improve Chemoprotective Properties
In this study, samples of broccoli were prepared in 6 different ways; standard boiling, standard boiling followed by the addition of mustard seeds, sous vide cooking at low temperature (70 °C) and sous vide cooking at higher temperature (100 °C) and sous vide cooking at higher temperature followed by the addition of mustard seeds at 2 different concentrations. The majority of consumers disliked the mildly cooked broccoli samples (70 °C, 12 min, sous vide) which had a hard and stringy texture. The highest mean consumer liking was for standard boiled samples (100 °C, 7 min). Addition of 1% mustard seed powder developed s...
Source: Journal of Food Science - August 25, 2014 Category: Food Science Authors: Sameer Khalil Ghawi, Yuchi Shen, Keshavan Niranjan, Lisa Methven Tags: S: Sensory & Food Quality Source Type: research
Effects of dog rose and watercress extracts on control of green mould decay and postharvest quality of orange fruits.
In conclusion, methanol extracts of dog rose fruits and especially watercress plant had the potential to be used against citrus green mould and even for the improvement of postharvest quality of orange fruits.
PMID: 24896635 [PubMed - as supplied by publisher] (Source: Natural Product Research)
Source: Natural Product Research - June 4, 2014 Category: Biochemistry Authors: Jafari S, Hassandokht M, Javan-Nikkhah M Tags: Nat Prod Res Source Type: research
A Case of Fasciola hepatica Mimicking Sepsis without Eosinophilia.
Abstract
Fasciolosis is a rare cause of hepatobiliary system infections and caused by the trematode Fasciola hepatica. It primarily infects sheeps or goats, and humans are accidental hosts. On laboratory findings, marked eosinophilia is present in most of the cases. Here, we report a case of fasciolosis without eosinophilia who was presented as sepsis and responded to therapy in second dose of triclabendazole. Sepsis like clinical presentation has been reported in few cases. Forty-eight year old female patient presented with high fever, abdominal pain, hypotension and tachycardia. The patient was considere...
Source: Turkish Society for Parasitology - June 1, 2014 Category: Parasitology Authors: Oner Vatan A, Mete B, Yemişen M, Kaya A, Kantarcı F, Saltoğlu N Tags: Turkiye Parazitol Derg Source Type: research
Psöriyazis ve Diyabetes Mellitus Tanılı Hastada Intestinal Strongyloidosis.
Abstract
Fasciolosis is a rare cause of hepatobiliary system infections and caused by the trematode Fasciola hepatica. It primarily infects sheep or goats, and humans are accidental hosts. On laboratory findings, marked eosinophilia is present in most of the cases. Here, we report a case of fasciolosis without eosinophilia who presented with sepsis and responded to therapy with a second dose of triclabendazole. Sepsis-like clinical presentation has been reported in few cases. A 48-year-old female patient presented with high fever, abdominal pain, hypotension, and tachycardia. The patient was considered as ...
Source: Turkish Society for Parasitology - June 1, 2014 Category: Parasitology Authors: Iraz M, Karaman U, Topukçu B, Doymaz MZ Tags: Turkiye Parazitol Derg Source Type: research
