Suppression of CXCR4 Expression by ITCs

This study demonstrates, for the first time, that cancer chemopreventive ITCs suppress CXCR4 expression in prostate cancer cells in vitro as well as in vivo. These results suggest that CXCR4 downregulation may be an important pharmacodynamic biomarker of cancer chemopreventative ITCs in prostate adenocarcinoma. Cancer Prev Res; 8(5); 365–74. ©2015 AACR.

http://cancerpreventionresearch.aacrjournals.org/cgi/content/short/8/5/365?rss=1

Source: Cancer Prevention Research - April 30, 2015 Category: Cancer & Oncology Authors: Sakao, K., Vyas, A. R., Chinni, S. R., Amjad, A. I., Parikh, R., Singh, S. V. Tags: Research Articles Source Type: research