Status of Intestinal Parasitic Infections among Primary School Children in Rivers State, Nigeria.
Authors: Abah AE, Arene FO Abstract Status of intestinal parasitic infections among primary school children in Rivers State, Nigeria, was investigated between January and December 2011. A total of 3,826 stool samples were collected from school children (1,828 males and 1998 females) in 36 primary schools from 13 local government areas of Rivers State. The samples were analyzed using wet saline/iodine and formol ether concentration methods. Of the 3,826 stool samples examined, 1059 (27.66%) were positive for different intestinal parasites, namely, Ascaris lumbricoides (51.78%), hookworm sp. (25.0%), Trichur...
Source: Journal of Parasitology Research - November 25, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Complex Membrane Channel Blockade: A Unifying Hypothesis for the Prodromal and Acute Neuropsychiatric Sequelae Resulting from Exposure to the Antimalarial Drug Mefloquine.
Authors: Quinn JC Abstract The alkaloid toxin quinine and its derivative compounds have been used for many centuries as effective medications for the prevention and treatment of malaria. More recently, synthetic derivatives, such as the quinoline derivative mefloquine (bis(trifluoromethyl)-(2-piperidyl)-4-quinolinemethanol), have been widely used to combat disease caused by chloroquine-resistant strains of the malaria parasite, Plasmodium falciparum. However, the parent compound quinine, as well as its more recent counterparts, suffers from an incidence of adverse neuropsychiatric side effects ranging from...
Source: Journal of Parasitology Research - November 20, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Rational Risk-Benefit Decision-Making in the Setting of Military Mefloquine Policy.
Authors: Nevin RL Abstract Mefloquine is an antimalarial drug that has been commonly used in military settings since its development by the US military in the late 1980s. Owing to the drug's neuropsychiatric contraindications and its high rate of inducing neuropsychiatric symptoms, which are contraindications to the drug's continued use, the routine prescribing of mefloquine in military settings may be problematic. Due to these considerations and to recent concerns of chronic and potentially permanent psychiatric and neurological sequelae arising from drug toxicity, military prescribing of mefloquine has r...
Source: Journal of Parasitology Research - November 20, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats.
Authors: Adediran OA, Uwalaka EC Abstract Anthelmintic drug resistance has led to the search for alternatives in controlling helminth infections. Fifty West African Dwarf goats without history of anthelmintic treatment were divided equally into five groups. Group A was treated with ivermectin injection subcutaneously, group B with levamisole subcutaneously, group C with albendazole orally, and group D with aqueous extract of Vernonia amygdalina and group E was untreated control. Faecal samples were collected before treatment from each animal and larval culture was carried out. Faecal egg count reduction (F...
Source: Journal of Parasitology Research - November 20, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Effect of Malathion on Reproductive Parameters of Engorged Female Rhipicephalus (Boophilus) microplus Ticks of Punjab Districts, India.
Authors: Jyoti, Singh NK, Singh H, Rath SS Abstract The present study was aimed at evaluating effects of malathion on the various reproductive parameters, namely, egg mass weight (EMW), reproductive index (RI), percentage inhibition of oviposition (%IO), and hatchability percentage of eggs of Rhipicephalus (Boophilus) microplus (Canestrini 1887) females from 19 districts of Punjab, India. The effect on various parameters was found to be dose dependent and more discernible upon exposure to higher concentrations. Complete cessation of egg laying was recorded in tick isolates on exposure to 5000 ppm and abo...
Source: Journal of Parasitology Research - November 10, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Comparison of Repellency Effect of Mosquito Repellents for DEET, Citronella, and Fennel Oil.
Authors: Yoon JK, Kim KC, Cho Y, Gwon YD, Cho HS, Heo Y, Park K, Lee YW, Kim M, Oh YK, Kim YB Abstract To confirm that Korean Food and Drug Administration (KFDA) guidelines are applicable to test the efficacy of mosquito repellents, these guidelines were used to test the efficacy and complete protection times (CPTs) of three representative mosquito repellents: N,N-diethyl-3-methylbenzamide (DEET), citronella, and fennel oil. The repellency of citronella oil decreased over time, from 97.9% at 0 h to 71.4% at 1 h and 57.7% at 2 h, as did the repellency of fennel oil, from 88.6% at 0 h to 61.2% at 1â€...
Source: Journal of Parasitology Research - November 5, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Lack of Association between Toxocara Exposure and Suicide Attempts in Psychiatric Patients.
Authors: Alvarado-Esquivel C, Hernández-Tinoco J, Sánchez-Anguiano LF Abstract Infection with Toxocara may affect the central nervous system. A high seroprevalence of Toxocara infection has been reported in psychiatric patients. To the best of our knowledge, there is no previous report about an association of Toxocara infection with suicide attempts. Therefore, we sought to determine whether Toxocara exposure is associated with suicide attempts in psychiatric patients. We studied 282 psychiatric outpatients (156 with suicide attempts and 126 without suicide attempts). Sera of patients were analyzed for t...
Source: Journal of Parasitology Research - October 22, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Effectiveness of Intermittent Preventive Treatment in Pregnancy with Sulphadoxine-Pyrimethamine against Submicroscopic falciparum Malaria in Central Region, Ghana.
Authors: Nwaefuna EK, Afoakwah R, Orish VN, Egyir-Yawson A, Boampong JN Abstract Malaria infections undetectable by microscopy but detectable by Polymerase Chain Reaction (PCR) (submicroscopic malaria) are common in endemic areas like Ghana. Submicroscopic malaria has been linked with severe pregnancy outcomes as well as contributing to malaria transmission. In this cross-sectional study 872 consenting pregnant women (gestation ≥ 20 weeks) were recruited from 8 hospitals in Central Region, Ghana, between July and December 2009. Malaria infection was detected by microscopy and PCR. Haemoglobin was measure...
Source: Journal of Parasitology Research - October 10, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Soil-Transmitted Helminth Infections and Associated Risk Factors among Schoolchildren in Durbete Town, Northwestern Ethiopia.
This study assessed the prevalence of STH infections and associated factors among schoolchildren in Durbete town, northwestern Ethiopia. Data about the sociodemographic and socioeconomic status of the children were collected using a questionnaire and stool samples were diagnosed using thick Kato-Katz smear. STH infection was more common among school-age children in Durbete town. Hookworm was the most frequent helminth species detected. The prevalence of STH infection was more in children who did not practice wearing shoes and washing hands before eating and in those who were older in age. Deworming of school-age children i...
Source: Journal of Parasitology Research - July 12, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Comparative Study of Malaria Prevalence among Travellers in Nigeria (West Africa) Using Slide Microscopy and a Rapid Diagnosis Test.
Authors: Dougnon TV, Bankole HS, Hounmanou YM, Echebiri S, Atchade P, Mohammed J Abstract Malaria is a major disease in Africa and leads to various public health problems. A study was carried out at the Aviation Medical Clinic Laboratory, Murtala Mohammed Airport, Ikeja, Lagos State, Nigeria, in 2014. The work aimed to determine the prevalence of malaria among patients attending the laboratory. Blood samples were therefore collected from 51 patients and subjected to both blood smear microscopy and a rapid immunochromatographic diagnostic test (SD BIOLINE Malaria Ag) for detection of, respectively, malaria ...
Source: Journal of Parasitology Research - June 14, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Prevalence of ovine haemonchosis in wukro, ethiopia.
Conclusion. The current finding revealed that significant numbers of sheep were affected by the parasites. Hence strategic deworming with good husbandry practice should be implemented. PMID: 25688297 [PubMed] (Source: Journal of Parasitology Research)
Source: Journal of Parasitology Research - February 19, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani.
Authors: Chakraborty S, Bhar K, Saha S, Chakrabarti R, Pal A, Siddhanta A Abstract Visceral leishmaniasis, a vector-borne tropical disease that is threatening about 350 million people worldwide, is caused by the protozoan parasite Leishmania donovani. Metalloids like arsenic and antimony have been used to treat diseases like leishmaniasis caused by the kinetoplastid parasites. Arsenic (III) at a relatively higher concentration (30 μg/mL) has been shown to have antileishmanial activity, but this concentration is reported to be toxic in several experimental mammalian systems. Nanosized metal (0) particles...
Source: Journal of Parasitology Research - January 24, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

The Life Cycle of the Parasitic Crustacean, Lernanthropus latis Yamaguti, 1954 (Copepoda: Lernanthropidae), on Marine-Cultured Fish, Lates calcarifer, from Setiu Wetland, Terengganu.
Authors: Abdul Khalid NQ, Shaharoum-Harrison F Abstract Parasitic crustaceans of Lernanthropus latis were isolated from the host, the seabass, Lates calcarifer, obtained from a cage culture in Setiu Wetland, Terengganu. The adult females with egg were kept alive in vials containing 20 mL of filtered seawater and incubated at 30°C. The eggs were monitored every hour and the hatching periods were recorded. Three developmental stages were observed, namely, nauplii I, nauplii II, and infective copepodid. The infective copepodids were then transferred into a tank containing 60 litres of seawater with 150 fin...
Source: Journal of Parasitology Research - January 13, 2015 Category: Parasitology Tags: J Parasitol Res Source Type: research

Subversion of Immunity by Leishmania amazonensis Parasites: Possible Role of Phosphatidylserine as a Main Regulator.
Authors: Mendes Wanderley JL, Costa JF, Borges VM, Barcinski M Abstract Leishmania amazonensis parasites cause progressive disease in most inbred mouse strains and are associated with the development of diffuse cutaneous leishmaniasis in humans. The poor activation of an effective cellular response is correlated with the ability of these parasites to infect mononuclear phagocytic cells without triggering their activation or actively suppressing innate responses of these cells. Here we discuss the possible role of phosphatidylserine exposure by these parasites as a main regulator of the mechanism underlying...
Source: Journal of Parasitology Research - December 1, 2014 Category: Parasitology Tags: J Parasitol Res Source Type: research

Association between Micronutrients (Vitamin A, D, Iron) and Schistosome-Specific Cytokine Responses in Zimbabweans Exposed to Schistosoma haematobium.
This study characterised a populations exposed to schistosome infections in terms of the relationship between micronutrients and immune responses. Levels of retinol binding protein (RBP; vitamin A marker), vitamin D, ferritin and soluble transferrin receptor (sTfR), and C reactive protein (CRP) were related to levels of schistosome specific cytokines (IFN-γ, IL-4/5/10) in 40 Zimbabweans (7-54 years) exposed to Schistosoma haematobium infection. 67.2% of the participants were deficient in vitamin D. RBP levels were within normal ranges but declined with age. The two indicators of iron levels suggested that although levels ...
Source: Journal of Parasitology Research - December 1, 2014 Category: Parasitology Tags: J Parasitol Res Source Type: research