Intraluminal deposits: A rare cause of glaucoma drainage implant total obstruction
CONCLUSIONS: Our study describes a new cause of total obstruction GDI tubes. The long-term use of timolol maleate and brinzolamide and their presence in the intraluminal solid sample collected from the blocked GDI tube suggest that the glaucoma medication may have a role in the pathogenesis. However, the exact mechanism is unknown and requires further studies.PMID:35575733 | DOI:10.1177/11206721221100074 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - May 16, 2022 Category: Opthalmology Authors: Juha V älimäki Praveena Nukareddy Hannu Uusitalo Ulla Aapola Source Type: research
Intraluminal deposits: A rare cause of glaucoma drainage implant total obstruction
CONCLUSIONS: Our study describes a new cause of total obstruction GDI tubes. The long-term use of timolol maleate and brinzolamide and their presence in the intraluminal solid sample collected from the blocked GDI tube suggest that the glaucoma medication may have a role in the pathogenesis. However, the exact mechanism is unknown and requires further studies.PMID:35575733 | DOI:10.1177/11206721221100074 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - May 16, 2022 Category: Opthalmology Authors: Juha V älimäki Praveena Nukareddy Hannu Uusitalo Ulla Aapola Source Type: research
Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment
CONCLUSION: PF tafluprost/timolol FC therapy provided statistically and clinically significant IOP reductions from Week 4 over the total 6-month period, in patients with OAG/OHT, regardless of the type of prior PGA or beta-blocker monotherapy used. Conjunctival hyperemia severity and CFS decreased significantly in prior bimatoprost and preserved latanoprost users, respectively.CLINICAL STUDY NUMBER: European Union electronic Register of Post-Authorization Studies (EU PAS) register number: EUPAS22204.PMID:35524840 | DOI:10.1007/s12325-022-02166-6 (Source: Adv Data)
Source: Adv Data - May 7, 2022 Category: Epidemiology Authors: Francesco Oddone James Kirwan Fernando Lopez-Lopez Marina Zimina Claudia Fassari G ábor Holló VISIONARY Study Group Source Type: research
Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment
CONCLUSION: PF tafluprost/timolol FC therapy provided statistically and clinically significant IOP reductions from Week 4 over the total 6-month period, in patients with OAG/OHT, regardless of the type of prior PGA or beta-blocker monotherapy used. Conjunctival hyperemia severity and CFS decreased significantly in prior bimatoprost and preserved latanoprost users, respectively.CLINICAL STUDY NUMBER: European Union electronic Register of Post-Authorization Studies (EU PAS) register number: EUPAS22204.PMID:35524840 | DOI:10.1007/s12325-022-02166-6 (Source: Adv Data)
Source: Adv Data - May 7, 2022 Category: Epidemiology Authors: Francesco Oddone James Kirwan Fernando Lopez-Lopez Marina Zimina Claudia Fassari G ábor Holló VISIONARY Study Group Source Type: research
Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment
ConclusionPF tafluprost/timolol FC therapy provided statistically and clinically significant IOP reductions from Week 4 over the total 6-month period, in patients with OAG/OHT, regardless of the type of prior PGA or beta-blocker monotherapy used. Conjunctival hyperemia severity and CFS decreased significantly in prior bimatoprost and preserved latanoprost users, respectively.Clinical Study NumberEuropean Union electronic Register of Post-Authorization Studies (EU PAS) register number: EUPAS22204. (Source: Advances in Therapy)
Source: Advances in Therapy - May 7, 2022 Category: Drugs & Pharmacology Source Type: research
Comparison of the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density: A Randomized Clinical Trial
To compare the differences in retinal vessel density (VD) between topical administration of latanoprostene bunod (LBN) ophthalmic solution 0.024% and timolol maleate 0.5% in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) and normal subjects. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 5, 2022 Category: Opthalmology Authors: Nevin W. El-Nimri, Sasan Moghimi, Rafaella C. Penteado, Elham Ghahari, Diya Yang, Nicole Brye, James Proudfoot, Jiun L. Do, Andrew Camp, Matthew Salcedo, Veronica Rubio, Robert N. Weinreb Source Type: research
Netarsudil-Induced Corneal Flattening in a Child with Secondary Open-Angle Glaucoma
We report a case of a child with secondary open-angle glaucoma who developed 6.5 diopters (D) of corneal flattening upon the addition of Rhopressa (0.02% netarsudil dimesylate solution) eye drops to a preexisting treatment regimen of timolol and latanoprost. This change in corneal power reversed after netarsudil, a rho-kinase inhibitor, was discontinued and replaced with Vyzulta (0.024% latanoprostene bunod ophthalmic solution). The 4-year-old female patient presented with bilateral secondary open-angle glaucoma from Paired Box 6 (PAX6)-related aniridia, aphakia, and persistent fetal vasculature. She was started on netarsu...
Source: Case Reports in Ophthalmology - May 2, 2022 Category: Opthalmology Source Type: research
Short-term efficacy of latanoprostene bunod for the treatment of open-angle glaucoma and ocular hypertension: a systematic literature review and a network meta-analysis
Conclusion
LBN was significantly more effective than the PGA unoprostone and most of the beta-blockers. Compared with the most widely used PGAs, LBN numerically outperformed latanoprost and travoprost and was similar to bimatoprost 0.01%. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - April 21, 2022 Category: Opthalmology Authors: Harasymowycz, P., Royer, C., Cui, A. X., Barbeau, M., Jobin-Gervais, K., Mathurin, K., Lachaine, J., Beauchemin, C. Tags: Open access Original articles - Clinical science Source Type: research
Bilateral Severe Herpes Simplex Endotheliitis with a Possible Association with Latanoprost
CONCLUSION: Bilateral simultaneous HSV endotheliitis is a rare condition and positive PCR test can help rule in the diagnosis. HSV keratitis is a known adverse event with Latanoprost use and can present atypically.PMID:35442856 | DOI:10.1080/09273948.2022.2065310 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 20, 2022 Category: Allergy & Immunology Authors: Arundhati Dvivedi Somasheila I Murthy Chandrasekhar Garudadri Esther Sheba Savitri Sharma Source Type: research
Bilateral Severe Herpes Simplex Endotheliitis with a Possible Association with Latanoprost
CONCLUSION: Bilateral simultaneous HSV endotheliitis is a rare condition and positive PCR test can help rule in the diagnosis. HSV keratitis is a known adverse event with Latanoprost use and can present atypically.PMID:35442856 | DOI:10.1080/09273948.2022.2065310 (Source: Herpes)
Source: Herpes - April 20, 2022 Category: Infectious Diseases Authors: Arundhati Dvivedi Somasheila I Murthy Chandrasekhar Garudadri Esther Sheba Savitri Sharma Source Type: research
Bilateral Severe Herpes Simplex Endotheliitis with a Possible Association with Latanoprost
CONCLUSION: Bilateral simultaneous HSV endotheliitis is a rare condition and positive PCR test can help rule in the diagnosis. HSV keratitis is a known adverse event with Latanoprost use and can present atypically.PMID:35442856 | DOI:10.1080/09273948.2022.2065310 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 20, 2022 Category: Allergy & Immunology Authors: Arundhati Dvivedi Somasheila I Murthy Chandrasekhar Garudadri Esther Sheba Savitri Sharma Source Type: research
