Pathogenesis of Central Serous ChorioRetinopathy and the Link between Choroidal Hyperpermeability and RPE Pump Reversal
: To describe 6 cases of acute central serous chorioretinopathy (CSCR) and the response to laser treatment, focusing on the underlying pathogenic mechanism. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 6, 2024 Category: Opthalmology Authors: Federica Fossataro, Claudia Fossataro, Neda Abraham, Yousef Fouad, Sarah Mrejen, Anna CS Tan, Shilo Voichaski, David Sarraf Tags: Perspective Source Type: research
Repeatability and agreement of 4 biometers measuring corneal astigmatism in eyes with irregular corneal astigmatism component
To investigate the repeatability and agreement of corneal astigmatism measurements in eyes with irregular corneal astigmatism component (ICAC) using four devices: IOLMaster 700 biometer, Lenstar 900 biometer, iTrace, and Pentacam. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 6, 2024 Category: Opthalmology Authors: Lan Wang, Xu Shao, Jin-Ling Fu, Jing-Jing Hu, Kai-Jing Zhou, Ran Li, A-Yong Yu Tags: Original Articles Source Type: research
Correlation Between Blue Fundus Autofluorescence and SD-OCT Measurements of Geographic Atrophy in Dry Age-Related Macular Degeneration
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) that is estimated to affect approximately 5 million people worldwide.1,2 Disease progression results from the irreversible loss of photoreceptors, retinal pigment epithelium (RPE), and choriocapillaris, leading to distinct atrophic lesions characteristic of the disease.1 Although good visual acuity may be retained initially, patients experience vision decline, increased difficulty performing tasks, and considerable loss of independence as lesions expand into the fovea. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 6, 2024 Category: Opthalmology Authors: Justis P. Ehlers, Conor McConville, Sari Yordi, Hasan Cetin, Yavuz Cakir, Gagan Kalra, Reem Amine, Jon Whitney, Victoria Whitmore, Michelle Bonnay, Jamie Reese, Julie Clark, Liansheng Zhu, Don Luo, Glenn J. Jaffe, Sunil K. Srivastava Tags: Original Articles Source Type: research
Pediatric and Adolescent Traumatic Macular Hole: A Systematic Review
The optimal management of pediatric traumatic macular holes (TMH) is unclear from lack of prospective randomized trials. The literature is divided into early ( ≤1month post-trauma), delayed (>1month) pars plana vitrectomy (PPV), and observation. Our aim is to find which group can achieve superior spectacle corrected visual acuity (VA), visual gain, and time for hole closure. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 4, 2024 Category: Opthalmology Authors: Youssef AH Helmy, Ayman G ElNahry, Ola El Zein, Suzanne Charbaji, Yoshihiro Yonekawa, Hana A Mansour, Hashem Abu Serhan, Mutaz Al-Nawaflh, Maurizio Battaglia Parodi, Basil K. Williams, Ahmad M Mansour Source Type: research
Accuracy of toric intraocular lens formulas with measured posterior corneal astigmatism of different orientations
To assess whether the use of measured posterior corneal astigmatism (PCA) values improves the prediction accuracy of toric intraocular lens power formulas, compared to predicted PCA values, when the orientation of the steep axis of PCA is non-vertical. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 3, 2024 Category: Opthalmology Authors: Stephen Stewart, Tun Kuan Yeo, Salissou Moutari, Richard McNeely, Jonathan E Moore Tags: Original Articles Source Type: research
Association of Retinal Thickness at Month 1 Post-Treatment with Later Thickness and Visual Acuity in Central Vein Occlusion
: To investigate the association of retinal thickness 1 month post-randomization (1 month after first study injection with aflibercept or bevacizumab) with later retinal thickness, visual acuity, and number of treatments in eyes with central or hemiretinal vein occlusion enrolled in the SCORE2 trial. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 3, 2024 Category: Opthalmology Authors: Ingrid U. Scott, Neal L. Oden, Michael S. Ip, Paul C. VanVeldhuisen, Barbara A. Blodi, SCORE2 Study Investigator Group Source Type: research
Causal Links Between Systemic Disorders and Keratoconus in European Population
The objective of this study was to establish the presence of a causal linkage between prevalent systemic diseases and keratoconus (KC). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 3, 2024 Category: Opthalmology Authors: Xiaxue Chen, Lanlan Chen Tags: Original Articles Source Type: research
Accuracy of Modern Intraocular Lens Formulas in Highly Myopic Eyes Implanted with Plate-Haptic Intraocular Lenses
Since the first successful implantation of an intraocular lens (IOL) by Dr. Harold Ridley in 1949, IOLs and power calculations have evolved over more than 70 years.1 During this period, there have been continual advancements in ocular biometry and IOL formulas, the diversity of IOL types has expanded, and patient expectations for postoperative visual quality have escalated, culminating in a paradigm shift in cataract surgery from purely visual restoration to a refractive procedure. Particularly for patients with high myopia (typically characterized by an axial length (AL) exceeding 26mm), cataract surgery holds dual import...
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Er Mo, Zexin Chen, Ke Feng, Zehui Zhu, Jialin Xu, Chenyuan Zhu, Pingjun Chang, Jin Li, Yun-e Zhao Tags: Original Articles Source Type: research
Intraocular immune response in human uveitis: time to look beyond animal models
To review the current and future approaches to investigating the intraocular immune response in human uveitis. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Soumyava Basu, Lynn Hassman, Shilpa Kodati, Colin J Chu Tags: Perspective Source Type: research
Progression or Aging? A Deep Learning Approach for Distinguishing Glaucoma Progression from Age-Related Changes in OCT scans
To develop deep learning (DL) algorithm to detect glaucoma progression using optical coherence tomography (OCT) images, in the absence of a reference standard. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Sayan Mandal, Alessandro A. Jammal, Davina Malek, Felipe A. Medeiros Tags: Original Articles Source Type: research
Reduction of Optic Disc Microvasculature and Retinal Nerve Fiber Layer Thinning in Patients with Glaucoma
To assess the relationship between the change of optic disc vessel density (ODVD) and retinal nerve fiber layer (RNFL) thinning in primary open-angle glaucoma (POAG) patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 1, 2024 Category: Opthalmology Authors: Min Hee Suh, Robert N. Weinreb, Linda M. Zangwill, Evan Walke Source Type: research
Importance of Baseline Fluorescein Angiography for Patients Presenting to Tertiary Uveitis Clinic
To ascertain whether the use of ultra-wide-field fluorescein angiography (UWFFA) at baseline visit alters the assessment of disease activity and localization, as well as the management of patients presenting to a tertiary uveitis clinic. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 1, 2024 Category: Opthalmology Authors: Irmak Karaca, Albert Bromeo, Hashem Ghoraba, Xun Lyu, Zheng Xian Thng, Cigdem Yasar, Amir Akhavanrezayat, Negin Yavari, Gunay Uludag Kirimli, Ngoc Tuong Trong Than, YongUn Shin, Ankur Sudhir Gupta, Anadi Khatri, S. Saeed Mohammadi, Jia-Horung Hung, Christ Tags: Original Articles Source Type: research
Outcomes of cataract surgery in eyes with axial length > 33 mm
The prevalence of myopia is increasing at an alarming rate worldwide, especially in Asia, and is projected to affect half of the global population by 2050.1 High myopia is defined differently, but is commonly characterized by an axial length (AL) exceeding 26.0 mm.2 As the AL elongates, there are significant changes in ocular structures, which are closely associated with various sight-threatening complications, such as cataract, macular pathologies, choroidal neovascularization, retinal detachment (RD) and glaucoma. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 30, 2024 Category: Opthalmology Authors: Yinglei Zhang, Yu Du, Anjian Wang, Xingtao Zhou, Yi Lu, Xiangjia Zhu Tags: Original Articles Source Type: research
Retinal image quality through an operating microscope with wavefront shaping extended depth of focus intraocular lens in model eye
Multifocal intraocular lenses (IOLs) are frequently used after cataract extractions because they reduce the need for spectacles which is convenient for the daily lives of patients.1,2 Multifocal IOLs have either refractive or diffractive optical structures to create multiple focal points.3,4 However, the discontinuous focus created by the multifocal IOLs leads to postoperative dysphotopsia including glare and halos due to light scattering. Extended depth-of-focus (EDoF) IOLs have an elongated focal point which results in an increase in the depth of focus, and they are used for the optical treatment of eyes after cataract e...
Source: American Journal of Ophthalmology - April 30, 2024 Category: Opthalmology Authors: Makoto Inoue, Yuji Itoh, Hiroko Bissen-Miyajima, Takashi Koto Tags: Original Articles Source Type: research
The effect of blue-light filtering intraocular lenses on the development and progression of macular atrophy in eyes with nAMD
To assess the effect of blue-light filtering (BLF) intraocular lenses (IOLs) on the development and progression of macular atrophy (MA) in eyes with neovascular age-related macular degeneration (nAMD). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 28, 2024 Category: Opthalmology Authors: Asaf Achiron, Omer Trivizki, Boris Knyazer, Uri Elbaz, Idan Hecht, Sohee Jeon, Piotr Kanclerz, Raimo Tuuminen Source Type: research
