Authorship Ethics: A Practical Approach
Authorship gives publishing credit and is the “medium of exchange” in the competitive environment of academia, used in performance reviews, salaries, and funding. However, conferring authorship often results in ethical dilemmas in academic medicine because of uneven power relationships that may impair objective decisions and result in a lac k of scientific integrity.1,2 Critically, ethical problems in authorship are much more common than data fabrication, modification, and falsification.3,4 (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Grant A. Justin, Ron W. Pelton, Fasika A. Woreta, Gary L. Legault Tags: Editorial Source Type: research

Wiping the Mud From Our Eyes: An Invited Editorial
In the transition from my second to third year of medical school, I made rounds with members of the teaching faculty. I studied their examination notes. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Robert Folberg Tags: Editorial Source Type: research

Retinal Fluid Volatility Associated with Interval Tolerance and Visual Outcomes in Diabetic Macular Edema in the VISTA Phase III Trial
To describe longitudinal retinal fluid dynamics on spectral domain OCT and to identify imaging biomarkers that predict the worsening of DME with interval extension during anti-vascular endothelial growth factor (VEGF) therapy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Justis P. Ehlers, Atsuro Uchida, Duriye Damla Sevgi, Ming Hu, Kim Reed, Alyson Berliner, Robert Vitti, Karen Chu, Sunil K. Srivastava Tags: Original Articles Source Type: research

Three-year outcomes of Cionni-modified capsular tension ring implantation in children under eight years old with ectopia lentis
To evaluate 3-year visual outcomes and complications post-Cionni-modified capsular tension ring (MCTR) implantation with an intraocular lens (IOL) in ectopia lentis patients aged ≤8 years. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Lei Cai, Xiaoyan Han, Yongxiang Jiang, Xiaodi Qiu, Dongjin Qian, Yi Lu, Jin Yang Tags: Original Articles Source Type: research

Comparison of Methods for Measuring Cyclodeviation
To compare the double Maddox rod test with other methods of measuring cyclodeviation. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Laura Lepor, Sarah R. Hatt, David A. Leske, Lindsay D. Klaehn, Andrea M. Kramer, Jonathan M. Holmes Tags: Original Articles Source Type: research

Comparative Study of Long-term Graft Survival between Penetrating Keratoplasty and Deep Anterior Lamellar Keratoplasty
Endothelial failure and immunological graft rejection remain long-term complications leading to late graft failure in Penetrating keratoplasty (PK). Deep anterior lamellar keratoplasty (DALK) has emerged as a viable alternative that enables preservation of the host ’s endothelial cells to eliminate risks of endothelial rejection and failure. The aim of this study was to compare long-term graft survival between PK and DALK. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Anshu Arundhati, Milton C.Y. Chew, Lim Li, Jodhbir Singh Mehta, Stephanie Shuang Lang, Hla Myint Htoon, Donald T.H. Tan Tags: Original Articles Source Type: research

Clinical Characteristics of Idiopathic Intracranial Hypertension in Patients Over 50 Years of Age: A multicenter clinical cohort study
To characterize the clinical features of idiopathic intracranial hypertension (IIH) in patients> age 50 years (yrs) relative to the typical IIH population and existing data on this older cohort (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 27, 2020 Category: Opthalmology Authors: Peter A. Downie, John J. Chen, M. Tariq Bhatti, Andrew T. Melson, Gregory P. Van Stavern, Collin M. McClelland, Bruce R. Lindgren, Jibran A. Sharieff, Michael S. Lee Tags: Original Articles Source Type: research

Ophthalmology and Ethics in the COVID-19 Era
The novel coronavirus, SARS-CoV-2 (COVID-19), has disrupted the practice of ophthalmology and threatens to forever alter how we care for our patients. Physicians across the country encounter unique clinical dilemmas daily. This manuscript presents a curated set of ethical dilemmas facing ophthalmologists both during and following the pandemic. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 26, 2020 Category: Opthalmology Authors: Kenneth M. Prager, Lora R. Dagi Glass, Marlene Wang, Royce W.S. Chen, Jeffrey M. Liebmann, George A. Cioffi Tags: Perspective Source Type: research

Cultivating The Physician-Patient Relationship in Ophthalmology
A strong physician-patient relationship is an integral component of providing patient care. Although the frequency of difficult patient encounters is not well described in ophthalmology, multiple studies have found that challenging encounters account for at least 15% of ambulatory physician-patient interactions1,2. Importantly, difficult clinical encounters have the potential to take a toll on provider satisfaction3 as well as clinical outcomes4,5. As physicians, we have a fundamental ethical responsibility to provide the best care possible for our patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 26, 2020 Category: Opthalmology Authors: Natalie A. Afshari, Rebecca R. Lian Tags: Editorial Source Type: research

Editorial Board
(Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Source Type: research

Table of Contents
(Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Source Type: research

Reply to Comment on: Rethinking the Hydroxychloroquine Dosing and Retinopathy Screening Guidelines
We appreciate the comments from Law and associates regarding our Perspective. They reiterate that pharmacokinetics (PK) of hydroxychloroquine (HCQ) are variable and that a daily dose produces variable blood concentrations depending on genetic factors, absorption variables, and effects of induction and inhibition of metabolizing enzymes, all topics that we reviewed in a previous publication.1 (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Authors: David J. Browning, Naoto Yokogawa, Paul B. Greenberg, Elliot Perlman Tags: Correspondence Source Type: research

Reply to Comment on Rethinking the Hydroxychloroquine Dosing and Retinopathy Screening Guidelines
We read with interest the study by Browning and associates1 and are writing to highlight the highly variable pharmacokinetics of hydroxychloroquine (HCQ) and its potential implications in HCQ-induced retinopathy (HCQR). The authors stated daily dosage was the most important and only modifiable risk factor for HCQR. Despite being the most important risk factor for HCQR, the dose itself does not completely predict HCQ exposure. HCQ has a variable and incomplete absorption (30%-100%).2 The reported volume of distribution ranges from 153 liters to 47,247 liters. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Authors: Lawrence Siu-Chun Law, Elaine Ah-Gi Lo, Siang Fei Yeoh Tags: Correspondence Source Type: research

Reply to Comment on: Evaluating Goldmann Applanation Tonometry Intraocular Pressure Measurement Agreement Between Ophthalmic Technicians and Physicians
We appreciate the thoughtful comments of Dr. Shu and associates. The authors raise the concern that circadian rhythm may have partly contributed to the differences in intraocular pressure (IOP) when comparing clinicians to technicians. While it is theoretically possible, we doubt that this would have been the case in the present study as patients were evaluated by physicians within a short time of being screened by technicians. Although we did not collect data for the exact amount of time elapsed between IOP measurements taken by the technician and those taken by the physician, the longest it would have been was an hour, a...
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Authors: David S. Friedman, Pradeep Y. Ramulu, Aleksandra Mihailovic, Varshini Varadaraj Tags: Correspondence Source Type: research

Comment on: Evaluating Goldmann Applanation Tonometry Intraocular Pressure Measurement Agreement Between Ophthalmic Technicians and Physicians
We read with great interest the article by Mihailovic and associates1 on Goldmann applanation tonometry agreement between ophthalmic technicians and physicians. Authors looked into one of the important aspects of patient management in glaucoma, the intraocular pressure (IOP) measurement by Goldmann applanation tonometry (GAT), and concluded that the physician-technician disagreement while measuring IOP using GAT was higher than 2 physicians even after educational intervention. We agree with the authors that, because GAT is a subjective test, one of the important limitations was the intra- and interobserver variability. (So...
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Authors: Abhipsa Sahu, Vinoth Arunaachalam, Premanand Chandran, Ganesh V. Raman Tags: Correspondence Source Type: research

Oxygen kinetics during corneal crosslinking with and without supplementary oxygen
To measure and simulate oxygen kinetics during corneal crosslinking (CXL) at different irradiances with and without supplementary oxygen. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 20, 2020 Category: Opthalmology Authors: Theo G. Seiler, Maria A. Komninou, Malavika H. Nambiar, Kaspar Schuerch, Beatrice E. Frueh, Philippe B üchler Tags: Original Articles Source Type: research

Reply to Comment on: Posterior Capsule Opacification With Two Hydrophobic Acrylic Intraocular Lenses: 3-Year Results of a Randomized Trial
We read with great interest the comment on our study “Posterior capsule opacification with two hydrophobic acrylic intraocular lenses: 3-Year results of a randomized trial.” Although puzzled about some inconsistencies of the authors' statements (generally low posterior capsule opacification [PCO] rates with no real clinical significance, but then stated very high PCO levels), we can hereby dispel the authors' concerns. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 19, 2020 Category: Opthalmology Authors: Christina Leydolt, Rupert Menapace Tags: Correspondence Source Type: research

Comment on: Allogenic Simple Limbal Epithelial Transplantation Versus Amniotic Membrane Grafting in the Early Management of Severe-Grade Ocular Chemical Injuries —A Retrospective Comparative Study
We have read with great interest the paper by Agarwal and associates.1 We agree that the establishment of an adequate approach and management of the acute stage of severe ocular chemical injuries is crucial for ensuring the best possible prognosis for these patients. Because of the nature of this disease, it would be extremely difficult to perform a randomized controlled trial to confirm the results perceived by this recently described technique. The findings and conclusions of their study are very interesting, and we would like to comment on the study design and statistical analysis performed. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 18, 2020 Category: Opthalmology Authors: Pedro-Ivan Navarro, Alejandro Lichtinger, Jos é Bareño Tags: Correspondence Source Type: research

Reply to Comment on: Sex Differences in the Repair of Retinal Detachments in the United States
We thank Venicasa et al. for their thoughtful correspondence. The authors raise good points regarding the possibility of gender disparities in the type of initial provider evaluation and increased misdiagnosis for women. Our study1 was designed to evaluate the repair of rhegmatogenous retinal detachment (RRD), and thus we are unable to comment on trends in misdiagnosis and providers. This area certainly warrants further investigation with a study design dedicated to this purpose. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 18, 2020 Category: Opthalmology Authors: Natalia F. Callaway, Daniel Vail, Ahmad Al-Moujahed, Cassie Ludwig, Marco H. Ji, Vinit B. Mahajan, Suzann Pershing, Darius M. Moshfeghi Tags: Correspondence Source Type: research

Uptake, persistence, and performance of weekly home monitoring of visual field in a large cohort of patients with glaucoma.
This study examines the short-term uptake, compliance, and performance of a tablet device used for home monitoring of visual field (VF-Home) by glaucoma patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 18, 2020 Category: Opthalmology Authors: Selwyn M. Prea, George YX. Kong, Robyn H. Guymer, Algis J. Vingrys Tags: Original Articles Source Type: research

Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials
To identify precursors of macular atrophy (MA) and of fibrotic scar (FS) in eyes treated with anti-VEGF through pixel-mapping analysis of baseline OCT. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 18, 2020 Category: Opthalmology Authors: Avni P. Finn, Maxwell Pistilli, Vincent Tai, Ebenezer Daniel, Gui-shuang Ying, Maureen G. Maguire, Juan E. Grunwald, Daniel F. Martin, Glenn J. Jaffe, Cynthia A. Toth, for the Comparison of Age-related Macular Degeneration Treatment Trials (CATT) Research Tags: Original Articles Source Type: research

Evaluation of a new test for the diagnosis of congenital dyschromatopsia in children: the Colour Vision Evaluation Test
to evaluate the validity, reproducibility and feasibility of the “COLOUR VISION EVALUATION TEST” (CVET) for the diagnosis of congenital dyschromatopsia. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 18, 2020 Category: Opthalmology Authors: Fish Anne-Laure, Alketbi Mohamed, Baillif Stephanie Tags: Original Articles Source Type: research

Reply to: Comment on Cross-over to Photodynamic Therapy or Micropulse Laser After Failure of Primary Treatment of Chronic Central Serous Chorioretinopathy
We thank the authors for their interest regarding our studies on chronic central serous chorioretinopathy (cCSC), including the PLACE trial and the REPLACE trial.1,2(+ reference to Correspondence, Wu and Roca, AJO, 2020) (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 11, 2020 Category: Opthalmology Authors: Thomas J. van Rijssen, Elon H.C. van Dijk, Paula Scholz, Myrte B. Breukink, Greet Dijkman, Petrus J.H. Peters, Roula Tsonaka, Robert E. MacLaren, Susan M. Downes, Sascha Fauser, Camiel J.F. Boon, Carel B. Hoyng Tags: Correspondence Source Type: research

Response to comment on: Non-Exudative Perifoveal Vascular Anomalous Complex: the sub-clinical stage of Perifoveal Exudative Vascular Anomalous Complex?
We thank Verhoekx and associates for their interest in our article1 and we are grateful we have the opportunity to address their concerns. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 11, 2020 Category: Opthalmology Authors: Riccardo Sacconi, Enrico Borrelli, Lea Querques, Francesco Bandello, Giuseppe Querques Tags: Correspondence Source Type: research

Reply to Letter from Novartis on “Is this a 737 Max Moment for Brolucizumab?”
We read the Correspondence by Kayath and Sauer1 from Novartis Pharmaceuticals with interest. Their letter fails to disclose the recent clarifications in the HAWK and HARRIER trial data, and by doing so they fail to reveal the true risks and benefits for the patients who might be given brolucizumab. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 10, 2020 Category: Opthalmology Authors: Philip J. Rosenfeld, David J. Browning Tags: Correspondence Source Type: research

Comment on Cross-over to Photodynamic Therapy or Micropulse Laser After Failure of Primary Treatment of Chronic Central Serous Chorioretinopathy
The PLACE Trial randomized eyes with chronic central serous chorioretinopathy (CSCR) to either half-dose photodynamic therapy (HD-PDT) or high density subthreshold micropulse laser (HSML). The reported outcomes favored the HD-PDT group.1 More recently Van Rijssen and colleagues 2 conducted the REPLACE Trial where patients with persistent subretinal fluid exiting the PLACE trial were invited to participate. Those eyes that had failed HD-PDT were treated with HSML and those that had failed HSML were treated with HD-PDT. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 10, 2020 Category: Opthalmology Authors: Lihteh Wu, Jos é A. Roca Tags: Correspondence Source Type: research

The Use of Systemic Steroids in the Treatment of Herpes Zoster Ophthalmicus-Related Ophthalmoplegia: Case Report and Case Meta-Analysis
The role of systemic steroids in the treatment of ophthalmoplegia in the setting of herpes zoster ophthalmicus (HZO) is controversial. We conducted a case-report based meta-analysis to investigate the role of systemic steroid in the recovery of efferent dysfunctions in HZO. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 9, 2020 Category: Opthalmology Authors: Anfei Li, Anika Tandon, Marc Dinkin, Cristiano Oliveira Tags: Original Articles Source Type: research

Comment on: Nonexudative Perifoveal Vascular Anomalous Complex: The Subclinical Stage of Perifoveal Exudative Vascular Anomalous Complex?
With great interest we read the article by Saconni et al1 where they describe the pre-exudative stage of exudative perifoveal vascular anomalous complex. The authors describe 6 eyes of 6 patients with nonexudative perifoveal vascular anomalous complex (nePVAC) of which 4 patients were followed for a mean of 21 ± 14 months. Three of these 4 patients developed exudation (ePVAC) after 15 ± 9 months. Based on these 3 patients the authors conclude that nePVAC may represent a pre-exudative stage of ePVAC. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 9, 2020 Category: Opthalmology Authors: Jennifer S.N. Verhoekx, Lisette M. Smid, Koenraad A. Vermeer, Jos é P. Martinez Ciriano, Suzanne Yzer Tags: Correspondence Source Type: research

AlloSLET versus AMG in the Early Management of Severe Grade Ocular Chemical Injuries: A Retrospective Comparative Study
We appreciate the interest expressed in and acknowledge the comments of Navarro and associates about our study.1 The first concern raised was about the groups not being matched with respect to demographic and preoperative clinical parameters (age, time to presentation, grade of injury and causative agent). We would like to repeat that the homogeneity among the groups was confirmed using regression analysis and thereby negated the possibility of a confounding bias. Only the above-mentioned 4 independent variables were included for multivariate analysis commensurate with the study sample size (n  = 77), ensuring that th...
Source: American Journal of Ophthalmology - November 7, 2020 Category: Opthalmology Authors: Shweta Agarwal, Bhaskar Srinivasan, Rishi Gupta, Geetha Iyer Tags: Correspondence Source Type: research

Comment on: Evaluation of a Multiplex Strip PCR Test for Infectious Uveitis: A Prospective Multicenter Study
With the development of clinical medicine and diagnostics, increasing numbers of diagnostic tests are becoming available.1 Evaluation of the performance of a new diagnostic test is becoming more important for understanding its usefulness and limitations before it is applied in a given clinical setting. An increasing number of researchers have used methodology derived from the Yerushalmy model2 to evaluate new diagnostic assays. The basis for the model is a 2  × 2 table consisting of 4 parameters: true positive, false positive, true negative, and false negative. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 7, 2020 Category: Opthalmology Authors: Dan Liu, Li-Rong Lin Tags: Correspondence Source Type: research

Public Speaker Characteristics at Meetings of the Dermatologic and Ophthalmic Drug Advisory Committee and the Ophthalmic Devices Panel
We investigated meetings of the Dermatologic and Ophthalmic Drug Advisory Committee (DODAC) and the Ophthalmic Devices Panel (ODP) of the Food and Drug Administration (FDA) to determine whether a relationship exists between receipt of industry payments by speakers of the Open Public Hearing (OPH) portion and the nature of their recommendations regarding treatment approval. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 6, 2020 Category: Opthalmology Authors: Mostafa H. Khattab, Michael Weaver, Courtney Cook, Nicholas Kinder, Matt Vassar Tags: Original Articles Source Type: research

Association of optic nerve head prelaminar schisis with glaucoma.
To compare the frequency of observing optic nerve head (ONH) prelaminar schisis by optical coherence tomography (OCT) in glaucoma and glaucoma suspect (GL/S) eyes versus healthy control (HC) eyes and to assess its association other markers of glaucoma severity. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - November 5, 2020 Category: Opthalmology Authors: Eugene A. Lowry, Steven L. Mansberger, Stuart K. Gardiner, Hongli Yang, Facundo Sanchez, Juan Reynaud, Shaban Demirel, Claude F. Burgoyne, Brad Fortune Tags: Original Articles Source Type: research

Comment on: Pattern Electroretinograms in Preperimetric and Perimetric Glaucoma
We congratulate and highly appreciate Jung and associates1 for their interesting study on pattern electroretinograms in preperimetric and perimetric glaucoma. However, we have a query for the authors. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 30, 2020 Category: Opthalmology Authors: Mandabi Sengupta, Prafulla Sarma, Shahinur Tayab, Chengchira A. Sangma Tags: Correspondence Source Type: research

Validation Of The Newly Proposed Who Classification System For Conjunctival Melanocytic Intraepithelial Lesions: A Comparison With The ‘C-Min’ And ‘Pam’ Classification Schemes
To compare the sensitivity, specificity, accuracy, and inter-observer agreement of the two most commonly used classification systems for conjunctival melanocytic intraepithelial lesions with the new WHO classification. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 29, 2020 Category: Opthalmology Authors: Tatyana Milman, Maya Eiger-Moscovich, Roger K. Henry, Robert Folberg, Sarah E. Coupland, Hans E. Grossniklaus, Hardeep Singh Mudhar, Charles G. Eberhart, Steffen Heegaard, Claudia Auw-H ädrich, Martina C. Herwig-Carl, Karin U. Löffler, Svetlana Cherepan Tags: Original Articles Source Type: research

Central Visual Field Defects in Patients with Distinct Glaucomatous Optic Disc Phenotypes
To investigate central visual field (VF) defects among four phenotypes of glaucomatous optic discs. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 28, 2020 Category: Opthalmology Authors: Eren Ekici, Sasan Moghimi, Huiyuan Hou, James Proudfoot, Linda M. Zangwill, Jiun L. Do, Won Hyuk Oh, Alireza Kamalipour, Jeffrey M. Liebmann, Carlos Gustavo De Moraes, Christopher A. Girkin, Nevin El-Nimri, Robert N. Weinreb Tags: Original Articles Source Type: research

Exposure to Secondhand Smoke in Children is Associated with a Thinner Retinal Nerve Fiber Layer: The Hong Kong Children Eye Study
To assess the effects of exposure to secondhand smoke (SHS) on peripapillary retinal nerve fiber layer (p-RNFL) thickness in children. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 28, 2020 Category: Opthalmology Authors: Jian Li, Nan Yuan, Wai Kit Chu, Carol Y. Cheung, Shumin Tang, Fen Fen Li, Li Jia Chen, Ka Wai Kam, Alvin L. Young, Patrick Ip, Clement C. Tham, Chi Pui Pang, Jason C. Yam Tags: Original Articles Source Type: research

Bacterial dispersion associated with various patient face mask designs during simulated intravitreal injections
To investigate bacterial dispersion with patient face mask use during simulated intravitreal injections. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 28, 2020 Category: Opthalmology Authors: Samir N. Patel, Raziyeh Mahmoudzadeh, Mirataollah Salabati, Rebecca R. Soares, John Hinkle, Jason Hsu, Sunir J. Garg, Carl D. Regillo, Allen C. Ho, Michael N. Cohen, M. Ali Khan, Yoshihiro Yonekawa, Allen Chiang, Omesh P. Gupta, Ajay E. Kuriyan Tags: Original Articles Source Type: research

An Increased Choroidal Microvasculature Dropout Size Is Associated With Progressive Visual Field Loss in Open-Angle Glaucoma
To investigate whether the choroidal microvasculature dropout (CMvD) increases in size over time among open-angle glaucoma (OAG) eyes presenting with CMvD at baseline and evaluate the association between longitudinal CMvD size increases and subsequent visual field (VF) progression. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 28, 2020 Category: Opthalmology Authors: Jin Yeong Lee, Joong Won Shin, Min Kyung Song, Ji Wook Hong, Michael S. Kook Tags: Original Articles Source Type: research

Association of visual acuity with eye-related quality of life and functional vision across childhood eye conditions
/Aims: We evaluated relationships between visual acuity and eye-related quality of life (ER-QOL) and functional vision in children, across a spectrum of pediatric eye conditions, using the Pediatric Eye Questionnaire (PedEyeQ). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 28, 2020 Category: Opthalmology Authors: David A. Leske, Sarah R. Hatt, Suzanne M. Wernimont, Yolanda S. Casta ñeda, Christina S. Cheng-Patel, Laura Liebermann, Eileen E. Birch, Jonathan M. Holmes. Tags: Original Articles Source Type: research

Long-term review of Penetrating Keratoplasty: A 20-year review in Asian eyes
To review the long-term outcomes of optical, therapeutic and tectonic forms of penetrating keratoplasty over a 20-year period in Asian eyes. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 27, 2020 Category: Opthalmology Authors: Arundhati Anshu, Lim Li, Hla Myint Htoon, de Benito-Llopis Laura, Lang Stephanie Shuang, Mehta Jodhbir Singh, Tan Donald Tiang Hwee Tags: Original Articles Source Type: research

Clinical and genetic analysis of 63 families demonstrating early and advanced characteristic fundus as the signature of CRB1 mutations
To reveal the characteristics of ocular changes in patients with biallelic CRB1 mutations. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 23, 2020 Category: Opthalmology Authors: Yingwei Wang, Wenmin Sun, Xueshan Xiao, Shiqiang Li, Xiaoyun Jia, Panfeng Wang, Qingjiong Zhang Tags: Original Articles Source Type: research

Progression of macular vessel density in primary open angle glaucoma: a longitudinal study
To evaluate the rate of progression of macular vessel density (mVD) in primary open angle glaucoma (POAG) and explore the relationship between the progression of mVD and macular ganglion cell-inner plexiform layer (mGCIPL) thickness and parapapillary retinal nerve fiber layer (pRNFL) thickness. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 23, 2020 Category: Opthalmology Authors: Cong Ye, Xiaoyan Wang, Marco Chak-yan Yu, Xiao Shang, Kun Zhou, Yan Tao, Fan Lu, Yuanbo Liang Tags: Original Articles Source Type: research

A systematic switch from originator infliximab to biosimilar infliximab in patients with non-infectious uveitis.
To investigate the efficacy of biosimilar infliximab compared to originator infliximab for the treatment of chronic non-infectious uveitis (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 23, 2020 Category: Opthalmology Authors: Noopur Kumar, Turid Follestad, H. Nida Sen, Dordi Austeng Tags: Original Articles Source Type: research

OCT Risk Factors for 3-Year Development of Macular Complications in eyes with “Resolved” Chronic Central Serous Chorioretinopathy.
To assess the relationship of demographics, clinical characteristics and structural optical coherence tomography (OCT) findings to development of sight-threatening macular complications (choroidal neovascularization [CNV], large areas of retinal pigment epithelium [RPE] atrophy and cystoid macular degeneration [CMD]) in a cohort of eyes with “resolved” chronic central serous chorioretinopathy (CSC) at inclusion (study baseline). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 22, 2020 Category: Opthalmology Authors: Enrico Borrelli, Marco Battista, Riccardo Sacconi, Francesco Gelormini, Lea Querques, Domenico Grosso, Giovanna Vella, Francesco Bandello, Giuseppe Querques Tags: Original Articles Source Type: research

Effect Of Mindfulness Meditation On Intraocular Pressure and Trabecular Meshwork Gene Expression: A Randomised Controlled Trial
To evaluate the effect of mindfulness meditation (MM) on intraocular pressure (IOP) and trabecular meshwork (TM) gene expression in patients with medically uncontrolled primary open angle glaucoma (POAG). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 22, 2020 Category: Opthalmology Authors: Tanuj Dada, Nithya Bhai, Neha Midha, Jyoti Shakrawal, Manoj Kumar, Priyanka Chaurasia, Shikha Gupta, Dewang Angmo, Rajkumar Yadav, Rima Dada, Ramanjit Sihota Tags: Original Articles Source Type: research

Editorial Board
(Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 21, 2020 Category: Opthalmology Source Type: research

Table of Contents
(Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 21, 2020 Category: Opthalmology Source Type: research

Improving Racial Diversity in the Ophthalmology Workforce: A Call to Action for Leaders in Ophthalmology
Racial injustice and disparities have been at the forefront of discussions in the United States during recent months. The tragic incidents of police brutality and the ravishing effects of Covid-19 on underrepresented minorities (URMs) —Black/African American, Hispanic/Latinx, and Native Americans—have highlighted the consequences of systemic racism that have been embedded in our country’s history.1 URMs are hospitalized due to Covid-19 at 4 to 5 times the rate of White people.2 Social determinants of health, such as employm ent, insurance, income, environmental exposures, and healthcare access, are underl...
Source: American Journal of Ophthalmology - October 21, 2020 Category: Opthalmology Authors: Ugochi T. Aguwa, Divya Srikumaran, Ninita Brown, Fasika Woreta Tags: Editorial Source Type: research

Reply to Comment on: Characterization of In  Vivo Biomechanical Properties in Macular Corneal Dystrophy
We are glad that our article1 was of great interest to Nair and associates and thank them for their in-depth insight and constructive comments. Their correspondence gives us a chance to elaborate on different aspects of our article. The results of our study showed that corneal resistance factor was significantly reduced in eyes with macular corneal dystrophy (MCD) compared with normal corneas.1 This parameter did not return to the normal value after penetrating keratoplasty (PK), which may suggest a decrease in the rigidity of the sclera, in addition to the cornea, in patients with MCD. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 20, 2020 Category: Opthalmology Authors: Sepehr Feizi, Zahra Karjou, Hamed Abbasi, Mohammad Ali Javadi, Amir A. Azari Tags: Correspondence Source Type: research

Comment on: Characterization of In  Vivo Biomechanical Properties in Macular Corneal Dystrophy
We read with interest the study by Feizi and associates1 elucidating the corneal biomechanics in patients with macular corneal dystrophy (MCD). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - October 20, 2020 Category: Opthalmology Authors: Sridevi Nair, Manpreet Kaur, Jeewan Singh Titiyal Tags: Correspondence Source Type: research