Digital Screen Time During COVID-19 Pandemic: Risk for a Further Myopia Boom?
To review the impact of increased digital device usage arising from lockdown measures instituted during the COVID-19 pandemic on myopia, and make recommendations for mitigating potential detrimental effects on myopia control. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 29, 2020 Category: Opthalmology Authors: Chee Wai WONG, Andrew TSAI, Jost B. Jonas, Kyoko Ohno-Matsui, James CHEN, Marcus ANG, Daniel Shu Wei TING Tags: Perspective Source Type: research

Minimally invasive 3600 approach to intraconal orbital tumors.
To evaluate clinically the efficacy of 3600 minimally invasive endoscopic surgery in patients with orbital intraconal tumors. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 29, 2020 Category: Opthalmology Authors: Joel Caballero-Garc ía., Carlos Aparicio-García., Yurledys Jhohana Linares-Benavides, Misael López-Sánchez, Franklyn Alain Abreu-Perdomo, Juvenal Huanca-Amaru. Tags: Original Articles Source Type: research

Vogt Koyanagi Harada disease managed with immunomodulatory therapy within 3 months of disease onset
To study the outcome of high dose corticosteroids with early addition of immunomodulatory therapy (IMT) on Vogt Koyanagi Harada disease (VKH). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 29, 2020 Category: Opthalmology Authors: Ei Ei Lin Oo, Soon-Phaik Chee, Kelvin Wong Kin Yan, Hla Myint Htoon Tags: Original Articles Source Type: research

A Comparison Between the Clinical Features of Pseudotumor Cerebri Secondary to Tetracyclines and Idiopathic Intracranial Hypertension
Comparisons between clinical features of tetracycline-induced pseudotumor cerebri (PTC-T) and those of idiopathic intracranial hypertension (IIH) are absent in the literature. We hypothesized that significant clinical differences between these etiologies exist and could be better understood by retrospective analysis. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 29, 2020 Category: Opthalmology Authors: Daniel R. Orme, Sravanthi Vegunta, Matthew A. Miller, Judith E.A. Warner, Christopher Bair, Molly McFadden, Alison Voigt Crum, Kathleen B. Digre, Bradley J. Katz Tags: Original Articles Source Type: research

Plateau iris and severity of primary angle closure glaucoma
To compare the distribution of plateau iris in eyes across varying severity of primary angle-closure glaucoma (PACG) using standardized ultrasound biomicroscopy (UBM) criteria. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 28, 2020 Category: Opthalmology Authors: Monisha E. Nongpiur, Sushma Verma, Tin A. Tun, Tina T. Wong, Shamira A. Perera, Tin Aung Tags: Original Articles Source Type: research

Automated Clinical Assessment of Corneal Guttae in Fuchs Endothelial Corneal Dystrophy
To describe the validation and implementation of an automated system, for the detection and quantification of guttae in Fuchs Endothelial Corneal Dystrophy (FECD). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Yu Qiang Soh, Gary SL. Peh, Sacha L. Naso, Viridiana Kocaba, Jodhbir S. Mehta Tags: Original Articles Source Type: research

Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study
To investigate anatomical mechanisms of angle narrowing by assessing ocular biometric determinants of anterior chamber angle (ACA) width. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Benjamin Y. Xu, Jacob Lifton, Bruce Burkemper, Xuejuan Jiang, Anmol A. Pardeshi, Sasan Moghimi, Grace Richter, Roberta McKean-Cowdin, Rohit Varma Tags: Original Articles Source Type: research

High Expression of PD-L1 and PD-L2 in Ophthalmic Sebaceous Carcinoma: The Case for a Clinical Trial of Checkpoint Inhibitors
To evaluate the expression of programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2) in ocular adnexal sebaceous carcinoma (OASC), and to appraise these findings within the context of recent comparable studies. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Natalie Wolkow, Frederick A. Jakobiec, Amir H. Afrogheh, Sara I. Pai, William C. Faquin Tags: Original Articles Source Type: research

Biomicroscopic Findings And Management Of Anterior Stromal Necrosis After Long-Term Implantacion Of Intacs
Purpose: To evaluate the visual, refractive and biomicroscopic findings pre- and post-treatment of the observed anterior stromal necrosis (ASN) after long-term INTACS intracorneal rings segment (ICRS) implantation.Design: Consecutive interventional case series.Subjects: All consecutive patients implanted with INTACS ICRS at a single center by one of the authors from October 2006 to October 2011 with a minimum follow-up time of 5 years were included.Methods: All INTACS were implanted using the Prolate system console and instrumentation from Addition Technology (Chicago, IL). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 27, 2020 Category: Opthalmology Authors: Juan-Carlos Abad, Isabel C. G ómez, María A. Henriquez, Jorge H. Donado Tags: Original Articles Source Type: research

Prevalence of PersistentCorneal Epithelial Defects in Chronic Ocular Graft- Versus-Host Disease
To establish the prevalence, clinical characteristics, and risk factors for persistent corneal epithelial defects (PED) in patients with chronic ocular graft-versus-host disease (oGVHD) and to determine visual outcomes after healing. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 25, 2020 Category: Opthalmology Authors: Shruti Sinha, Rohan Bir Singh, Thomas H. Dohlman, Mengyu Wang, Yukako Taketani, Jia Yin, Reza Dana Tags: Original Articles Source Type: research

Retinal vasculometry associations with glaucoma; findings from the European Prospective Investigation of Cancer-Norfolk Eye study
To examine retinal vasculometry associations with different glaucomas in older British people. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 25, 2020 Category: Opthalmology Authors: Alicja R. Rudnicka, Christopher G. Owen, Roshan A. Welikala, Sarah A. Barman, Peter H. Whincup, David P. Strachan, Michelle P.Y. Chan, Anthony P. Khawaja, David C. Broadway, Robert Luben, Shabina A. Hayat, Kay-Tee Khaw, Paul J. Foster Tags: Original Articles Source Type: research

Clinical and imaging factors associated with the outcomes of tubercular serpiginous-like choroiditis
To analyze baseline clinical and imaging risk factors associated with poor outcome in patients with tubercular serpiginous-like choroiditis (TB SLC). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 22, 2020 Category: Opthalmology Authors: Aniruddha Agarwal, Alessandro Marchese, Alessandro Rabiolo, Rupesh Agrawal, Reema Bansal, Vishali Gupta Tags: Original Articles Source Type: research

Automated Non-contact Facial Topography Mapping, 3-Dimensional Printing and Silicone Casting of Orbital Prosthesis
A proof-of-concept workflow study for the fabrication of custom orbital exenteration prostheses via automated non-contact scanning, 3D printing, and silicone casting. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Ernesto H. Weisson, Mauro Fittipaldi, Carlos A. Concepcion, Daniel Pelaez, Landon Grace, David T. Tse Tags: Original Articles Source Type: research

Analysis of Predisposing Clinical Features for Worsening Traction after Treatment of Familial Exudative Vitreoretinopathy in Children
To determine the incidence of worsening vitreoretinal traction after laser for familial exudative vitreoretinopathy (FEVR), and to determine whether any baseline clinical features are associated with worsening. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: G. Baker Hubbard, Alexa L. Li Source Type: research

Population based incidence of optic neuritis in the era of aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies
Over the past 15 years, 2 new biomarkers have been discovered that allow for further characterization of the etiology of atypical optic neuritis: aquaporin-4 (AQP4)-immunoglobulin G (IgG) and myelin oligodendrocyte glycoprotein (MOG)-IgG. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Mohamed B. Hassan, Caroline Stern, Eoin P. Flanagan, Sean J. Pittock, Amy Kunchok, Robert C. Foster, Jiraporn Jitprapaikulsan, David O. Hodge, M Tariq Bhatti, John J. Chen Tags: Original Articles Source Type: research

An ophthalmic rating scale to assess ocular involvement in juvenile CLN3 disease
The objective of the study was to design an ophthalmic rating scale for CLN3 disease in order to quantify disease progression. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Dulz Simon, Atiskova Yevgeniya, Wibbeler Eva, Wildner Jan, Wagenfeld Lars, Schwering Christoph, Nickel Miriam, Bartsch Udo, Spitzer Martin Stephan, Schulz Angela Tags: Original Articles Source Type: research

Femtosecond laser assisted deep anterior lamellar keratoplasty for keratoconus: multi-surgeon results
To compare the clinical outcomes in femtosecond laser assisted deep anterior lamellar keratoplasty (F-DALK) to manual non-laser deep anterior lamellar keratoplasty (M-DALK) for keratoconus in a multi-surgeon public healthcare setting. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Kunal A. Gadhvi, Vito Romano, Luis Fern ández-Vega Cueto, Francesco Aiello, Alexander C. Day, Daniel M. Gore, Bruce D. Allan Tags: Original Articles Source Type: research

Epidemiology and the Estimated Burden of Microbial Keratitis on the Health Care System in Taiwan: A 14-Year Population-Based Study
To investigate the epidemiological characteristics of microbial keratitis and its overall burden on the healthcare system in Taiwan. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 21, 2020 Category: Opthalmology Authors: Yeo-Yang Koh, Chi-Chin Sun, Ching-Hsi Hsiao Tags: Original Articles Source Type: research

Lightweight Learning-based Automatic Segmentation of Subretinal Blebs on Microscope-Integrated Optical Coherence Tomography Images
Subretinal injections of therapeutics are commonly used to treat ocular diseases. Accurate dosing of therapeutics at target locations is crucial but difficult to achieve using subretinal injections due to leakage, and there is no method available to measure the volume of therapeutics successfully administered to the subretinal location during surgery. Here we introduce the first automatic method for quantifying the volume of subretinal blebs, using porcine eyes injected with Ringer ’s lactate solution as samples. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Zhenxi Song, Liangyu Xu, Jiang Wang, Reza Rasti, Ananth Sastry, Jianwei D. Li, William Raynor, Joseph A. Izatt, Cynthia A. Toth, Lejla Vajzovic, Bin Deng, Sina Farsiu Tags: Original Articles Source Type: research

Whole-Exome Sequencing of Patients with Posterior Segment Uveitis
To elucidate molecular risk factors for posterior segment uveitis using a functional genomics approach. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Angela S. Li, Gabriel Velez, Benjamin Darbro, Marcus A. Toral, Jing Yang, Stephen H. Tsang, Polly J. Ferguson, James C. Folk, Alexander G. Bassuk, Vinit B. Mahajan Tags: Original Articles Source Type: research

Spatial Functional Characteristics of East Asian Patients with Occult Macular Dystrophy (Miyake disease); EAOMD Report No.2
To describe the functional phenotypic features of East Asian patients with RP1L1-associated occult macular dystrophy (i.e., Miyake disease). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Lizhu Yang, Kwangsic Joo, Kazushige Tsunoda, Mineo Kondo, Yu Fujinami-Yokokawa, Gavin Arno, Nikolas Pontikos, Xiao Liu, Natsuko Nakamura, Toshihide Kurihara, Kazuo Tsubota, Takeshi Iwata, Hui Li, Xuan Zou, Shijing Wu, Zixi Sun, Seong Joon Ahn, Min Seok Ki Tags: Original Articles Source Type: research

Comparison of long-term rotational stability of three commonly implanted intraocular lenses
To compare rotational stability and its influencing factors in 3 different widely used hydrophobic acrylic intraocular lenses (IOL) from end of surgery (EoS) to 4 to 7 months (6m) in over 380 eyes. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Daniel Schartm üller, Luca Schwarzenbacher, Elias Laurin Meyer, Sabine Schriefl, Christina Leydolt, Rupert Menapace Tags: Original Articles Source Type: research

The extent of angioid streaks correlates with macular degeneration in pseudoxanthoma elasticum
To investigate whether the extent of Bruch ’s membrane (BM) calcification is associated with choroidal neovascularization (CNV) and macular atrophy in patients with pseudoxanthoma elasticum (PXE) by using the extent of angioid streaks as a surrogate marker for the degree of BM calcification.Design; Retrospective cross-sectional study. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 20, 2020 Category: Opthalmology Authors: Sara Risseeuw, Jeannette Ossewaarde – van Norel, Colette van Buchem, Wilko Spiering, Saskia M. Imhof, Redmer van Leeuwen Tags: Original Articles Source Type: research

Comment on: Management of Congenital Aniridia-Associated Keratopathy: Long-term Outcomes From a Tertiary Referral Center
We read with great interest the article written by Yazdanpanah and associates on “Management of Congenital Aniridia-Associated Keratopathy: Long-term Outcomes From a Tertiary Referral Center,” involving 92 eyes of congenital aniridia in a retrospective case series.1 Aniridia-associated keratopathy (AAK) is rare but a chronic disabling condition with limited literature on its management strategy. We appreciate the authors for their excellent work on this topic. Stage-related therapy of congenital AAK has been described previously in literature with minimally invasive management strategy for early stages of the d...
Source: American Journal of Ophthalmology - July 17, 2020 Category: Opthalmology Authors: Deepali Singhal, Ritu Nagpal, Prafulla K. Maharana Tags: Correspondence Source Type: research

Reply to Comment on: Management of Congenital Aniridia-Associated Keratopathy: Long-term Outcomes From a Tertiary Referral Center
We thank Drs Singhal, Nagpal, and Maharana for their interest in and comment on our work regarding the management of aniridia-associated keratopathy (AAK). In answer to the question regarding the surgical techniques for limbal stem cell transplantation (LSCT), we have previously published our techniques.1,2 We refer the authors to those publications for more details and encourage them to directly contact 1 of the corresponding authors for more specific questions. As for the choice of donor tissue, the great majority of LSCTs were cadaveric keratolimbal allograft (KLAL) and only a few cases had undergone living-related LSCT...
Source: American Journal of Ophthalmology - July 17, 2020 Category: Opthalmology Authors: Ghasem Yazdanpanah, Maria S. Cortina, Ali R. Djalilian Tags: Correspondence Source Type: research

Effects of Induced Astigmatism on Spectral Domain-OCT Angiography Quantitative Metrics
To analyze the effect of induced astigmatism on en-face spectral-domain optical coherence tomography angiography (SD-OCTA) quantitative metrics. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Jesse J. Jung, Yu Qiang Soh, Patricia Sha, Sophia Yu, Mary K. Durbin, Quan V. Hoang Tags: Original Articles Source Type: research

5-year Outcomes of Converted Mushroom Keratoplasty from Intended DALK Mandate 9mm Diameter DALK as the Optimal Approach to Keratoconus
To compare the 5-year outcomes of 9mm deep anterior lamellar keratoplasty (DALK) for keratoconus against those converted to mushroom keratoplasty (MK). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: James Myerscough, Harry Roberts, Angeli Christy Yu, Mohamed Elkadim, Cristina Bovone, Massimo Busin Tags: Original Articles Source Type: research

A Cost-Benefit Analysis of VEGF-Inhibitor Therapy for Neovascular Age-Related Macular Degeneration in the United States
To perform a societal cost-benefit analysis comparing intravitreal bevacizumab (Avastin ®), ranibizumab (Lucentis®) and aflibercept (Eylea®) monotherapies for treating neovascular age-related macular degeneration (NVAMD). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Gary C. Brown, Melissa M. Brown, Sara B. Rapuano, David Boyer Tags: Original Articles Source Type: research

Ophthalmic corticosteroids in pregnant women with allergic conjunctivitis and adverse neonatal outcomes: propensity score analyses
The risks of topical ophthalmic corticosteroids during pregnancy remain unclear. We investigated the association between exposure to topical ophthalmic corticosteroids during pregnancy and adverse neonatal outcomes. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Yohei Hashimoto, Nobuaki Michihata, Hayato Yamana, Daisuke Shigemi, Kojiro Morita, Hiroki Matsui, Hideo Yasunaga, Makoto Aihara Tags: Original Articles Source Type: research

Unique geospatial accumulations of uveal melanoma
Uveal melanoma (UM) is the most common primary malignant eye tumor in adults, though rare with 2500 cases diagnosed annually in the US. Despite a growing understanding of the molecular characteristics, there remains uncertainty regarding epidemiologic trends and environmental risk factors. We have identified three geographic accumulations of UM: 1) Huntersville, NC, 2) Auburn, AL, and 3) Broome/Tioga Counties, NY. Evaluation into these groups will guide ongoing efforts to discover potential risk factors and assist with future treatment and prevention. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Marlana Orloff, Mike Brennan, Shingo Sato, Carol L. Shields, Jerry A. Shields, Sara Lally, Arman Mashayekhi, John Mason, Miguel Materin, Michael Mastrangelo, Takami Sato Tags: Original Articles Source Type: research

Lid-Related Keratopathy in Stevens-Johnson Syndrome: Natural Course and Impact of Therapeutic Interventions in Children and Adults
To compare the long-term visual outcomes of different management strategies in children and adults with Stevens-Johnson Syndrome (SJS)-induced chronic lid-related keratopathy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Swapna S. Shanbhag, Sahil Shah, Madhu Singh, Chirag Bahuguna, Pragnya R. Donthineni, Sayan Basu Tags: Original Articles Source Type: research

Crystalline Lens Power and Associated Factors in Highly Myopic Children and Adolescents Aged 4 to 19 Years
To investigate the distribution characteristics of lens power in highly myopic Chinese children and adolescents and its association with age, axial length (AL) and spherical equivalent (SE). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Tianyu Cheng, Junjie Deng, Shuyu Xiong, Suqin Yu, Bo Zhang, Jingjing Wang, Wei Gong, Huijuan Zhao, Mengli Luan, Mengjun Zhu, Jianfeng Zhu, Haidong Zou, Xian Xu, Xiangui He, Xun Xu Tags: Original Articles Source Type: research

Differences in Clinical Features of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis in White and Asian Race
To determine whether clinical features and visual outcomes of myelin oligodendrocyte glycoprotein antibody-associated optic neuritis (MOG-ON) differ between subjects who are White compared with those who are Asian. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 15, 2020 Category: Opthalmology Authors: Tanyatuth Padungkiatsagul, John J. Chen, Panitha Jindahra, Tetsuya Akaishi, Toshiyuki Takahashi, Ichiro Nakashima, Takayuki Takeshita, Heather E. Moss Tags: Original Articles Source Type: research

Determining the Tractional Forces on Vitreoretinal Interface Using Computer Simulation Model in Abusive Head Trauma
Abusive head trauma (AHT) is the leading cause of infant death and long-term morbidity from injury. The ocular consequences of AHT are controversial, and the pathophysiology of retinal research findings is still not clearly understood. It has been postulated that vitreoretinal traction plays a major role in the retinal findings. A computer simulation model was developed to evaluate the vitreoretinal traction and determine whether the distribution of forces in different layers and locations of the retina can explain the patterns of retinal hemorrhage (RH) seen in AHT. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 11, 2020 Category: Opthalmology Authors: Donny W. Suh, Helen H. Song, Hozhabr Mozafari, Wallace B. Thoreson Source Type: research

Reply to Comment on: Racial, Ethnic, and Socioeconomic Disparities in Retinoblastoma Enucleation: A Population-Based Study, SEER 18 2000 –2014
We are thankful for the opportunity to respond to the issues raised in Dr Brown's letter. We would also like to thank Dr Brown for these comments and for expressing interest in our work.1 (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 10, 2020 Category: Opthalmology Authors: Nitya Rajeshuni, Alice S. Whittemore, Cassie A. Ludwig, Prithvi Mruthyunjaya, Darius M. Moshfeghi Tags: Correspondence Source Type: research

Corrigendum for Macular Vascularity in Ischemic Optic Neuropathy Compared to Glaucoma by Projection-Resolved Optical Coherence Tomography Angiography
We would like to clarify some aspects of our article, which appeared in the January 2020 issue of the American Journal of Ophthalmology.1 Although 37 eyes with moderate and advanced glaucoma, 19 eyes with atrophic nonarteritic anterior ischemic optic neuropathy, and 40 eyes of normal subjects were included in this study and imaged using optical coherence tomography angiography (OCT-A), data from 5 glaucoma eyes, the entirety of the data from subjects enrolled from New York Eye and Ear Infirmary, lacked uniform OCT data (retinal nerve fiber layer and ganglion cell complex) as well as adequate quality macular OCT-A data. (So...
Source: American Journal of Ophthalmology - July 10, 2020 Category: Opthalmology Authors: Masoud Aghsaei Fard, Robert Ritch Tags: Correspondence Source Type: research

Direct Versus Indirect Corneal Neurotization for the Treatment of Neurotrophic Keratopahty: a Multicenter Prospective Comparative Study
To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN] for the treatment of neurotrophic keratopathy (NK). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 10, 2020 Category: Opthalmology Authors: Paolo Fogagnolo, Giuseppe Giannaccare, Federico Bolognesi, Maurizio Digiuni, Laura Tranchina, Luca Rossetti, Angelica Dipinto, Fabiana Allevi, Alessandro Lozza, Dimitri Rabbiosi, Silvia Mariani, Marco Pellegrini, Federica E. Cazzola, Simone Bagaglia, Cosi Tags: Original Articles Source Type: research

Three-Year Outcomes of Tri-Folded Endothelium-In Descemet Membrane Endothelium Keratoplasty with Pull-Through Technique
To report the 3-year outcomes of tri-folded, endothelium-in Descemet membrane endothelial keratoplasty (DMEK) using bimanual pull-through delivery technique. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 10, 2020 Category: Opthalmology Authors: Angeli Christy Yu, James Myerscough, Rossella Spena, Fiorella Fusco, Sergiu Socea, Luca Furiosi, Luigi De Rosa, Cristina Bovone, Massimo Busin Tags: Original Articles Source Type: research

Temporal Raphe Sign in Elderly Patients with Large Optic Disc Cupping: Its Evaluation as a Predictive Factor for Glaucoma Conversion
To determine baseline clinical features associated with conversion to glaucoma in elderly patients with large optic-disc cupping (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 8, 2020 Category: Opthalmology Authors: Ahnul Ha, Young Kook Kim, Jin-Soo Kim, JinWook Jeoung, Ki Ho Park Tags: Original Articles Source Type: research

Reply to Morphologic Features of Buried Optic Disc Drusen on En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
We greatly appreciate the interest that Sibony and associates1 demonstrated in our study. The authors raised an important question regarding the definition of optic disc drusen (ODD) in our study. We know that the Optic Disc Drusen Studies Consortium defined ODD as hyporeflective lesions surrounded by hyperreflective capsules using optical coherence tomography (OCT). We previously showed that this kind of visible drusen can be observed especially in the eyes of the elderly associated with degenerative changes on OCT. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 6, 2020 Category: Opthalmology Authors: Min Seok Kim, Kyoung Min Lee, Jeong-Min Hwang, Hee Kyung Yang, Se Joon Woo Tags: Correspondence Source Type: research

Comment on Accuracy of Intraocular Lens Formulas in Eyes With Keratoconus
We read with great interest the excellent article by Wang and associates.1 We recognize that intraocular lens power calculation in patients with keratoconus is challenging. Determining the accurate keratometry readings, axial length, and anterior chamber depth can be difficult in these eyes, which can lead to inaccurate and unpredictable results with a tendency to hyperopic refractive surprises.1 –4 To the best of our knowledge, this is the first study that reports the Barrett Universal II as the most accurate formula in mild keratoconus (stages I and II). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 6, 2020 Category: Opthalmology Authors: Eduardo Gonzalez-Lubcke, Nicolas Kahuam-Lopez, Alejandro Navas, Arturo Ramirez-Miranda, Enrique O. Graue-Hernandez Tags: Correspondence Source Type: research

A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy
To compare the efficacy of intraoperative scleral application with subconjunctival injection of mitomycin C (MMC) in trabeculectomy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 6, 2020 Category: Opthalmology Authors: Jiun L. Do, Benjamin Y. Xu, Brandon Wong, Andrew Camp, Philip Ngai, Christopher Long, James Proudfoot, Sasan Moghimi, Diya Yang, Derek S. Welsbie, Robert N. Weinreb Tags: Original Articles Source Type: research

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Hendricks TM, Bhatti MT, Hodge DO, Chen JJ. Incidence, Epidemiology, and Transformation of Ocular Myasthenia Gravis: A Population-Based Study. Am J Ophthalmol 2019;205:99 –105. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 4, 2020 Category: Opthalmology Tags: Corrigendum Source Type: research

Sex Differences in the Repair of Retinal Detachments in the United States
To determine differences between women and men in the repair of rhegmatogenous retinal detachments (RRD) in the United States. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 4, 2020 Category: Opthalmology Authors: Natalia F. Callaway, Daniel Vail, Ahmad Al-Moujahed, Cassie Ludwig, Marco H. Ji, Vinit B. Mahajan, Suzann Pershing, Darius M. Moshfeghi Tags: Original Articles Source Type: research

The Short-Term Effect of a Single Lapse in Anti-Vascular Endothelial Growth Factor Treatment for Diabetic Macular EdemaWithin Routine Clinical Practice
Diabetic macular edema (DME) is a leading cause of vision loss in diabetics. Anti-vascular endothelial growth factor (VEGF) therapy has been shown to be an effective treatment option for DME, although the injections are costly and require frequent visits which increases the risk for unintended treatment lapses. The aim of this study is to characterize the effects of an unintended treatment lapse in patients with DME undergoing anti-VEGF therapy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 4, 2020 Category: Opthalmology Authors: Siri P. Yalamanchili, Christopher M. Maatouk, Daniel U. Enwere, Thais F. Conti, Grant L. Hom, Isaac N. Briskin, Tyler E. Greenlee, Amy S. Babiuch, Rishi P. Singh Tags: Original Articles Source Type: research

EvaluatingGoldmann applanation tonometryintraocular pressure measurement agreement between ophthalmic technicians and physicians
To examine IOP measurement disagreement between technicians and physicians and the impact of an educational intervention on the short and long-term disagreement in IOP measurement using Goldmann applanation tonometry. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 4, 2020 Category: Opthalmology Authors: Aleksandra Mihailovic, Varshini Varadaraj, Pradeep Y. Ramulu, David S. Friedman Tags: Original Articles Source Type: research

Incidence and outcome of uveitic glaucoma in eyes with intermediate, posterior or panuveitis followed up to 10 years after randomization to fluocinolone acetonide implant or systemic therapy.
To evaluate long-term risk and outcomes of glaucoma in eyes with intermediate, posterior, and panuveitis managed with systemic or fluocinolone acetonide (0.59 mg, “implant”) therapy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 3, 2020 Category: Opthalmology Authors: John H. Kempen, Mark L. Van Natta, David S. Friedman, Michael M. Altaweel, Husam Ansari, James P. Dunn, Susan G. Elner, Janet T. Holbrook, Lyndell L. Lim, Elizabeth A. Sugar, Douglas A. Jabs, for the Multicenter Uveitis Steroid Treatment (MUST) Trial and Tags: Original Articles Source Type: research

Comment On: Accuracy of Intraocular Lens Formulas in Eyes With Keratoconus
We appreciate the comments and inquiry from Gonzalez-Lubcke and associates. Intraocular lens (IOL) power calculations in eyes with keratoconus is indeed more unpredictable than in normal eyes using third and fourth-generation IOL formulas. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 1, 2020 Category: Opthalmology Authors: Kendrick M. Wang, Albert S. Jun, John G. Ladas, Aazim A. Siddiqui, Fasika Woreta, Divya Srikumaran Tags: Correspondence Source Type: research

Racial, Ethnic, and Socioeconomic Disparities in Retinoblastoma Enucleation: A Population-Based Study, SEER 18 2000 –2014
I read with interest the article by Rajeshuni and associates1 on socioeconomic disparities in retinoblastoma (RB) treatment. The authors reported that the rate of enucleation was higher in children of nonwhite race and lower socioeconomic status (SES). They concluded that “these disparities appear unrelated to delayed diagnosis.” The implication is that a nonpoor nonminority child would receive advanced globe-saving therapies such as intravitreal or intra-arterial chemotherapy, and a poor minority child with an identical tumor burden would be enucleated. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 1, 2020 Category: Opthalmology Authors: Sandra M. Brown Tags: Correspondence Source Type: research

Prevalence and Consequences of Perceived Vision Difficultyin Aging Adults with HIV-infection
Despite well-known ocular complications of HIV-related immune suppression, few studies have examined the prevalence and consequences of visual impairment among aging long term survivors of HIV. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - July 1, 2020 Category: Opthalmology Authors: Alison G. Abraham, Ann Ervin, Bonnie Swenor, Pradeep Ramulu, Roomasa Channa, Xiangrong Kong, Valentina Stosor, M. Reuel Friedman, Roger Detels, Michael Plankey Tags: Original Articles Source Type: research