Association of ocular manifestations of Marfan syndrome with cardiovascular complications
To evaluate associations between ocular manifestations of Marfan syndrome and cardiovascular complications. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 23, 2024 Category: Opthalmology Authors: Elaine M. Tran, Karen M. Wai, Andrea L. Kossler, Prithvi Mruthyunjaya, Ehsan Rahimy, Euna B. Koo Tags: Original Articles Source Type: research
Ultra-Wide-Field Optical Coherence Tomography and Gaussian Curvature to Assess Macular and Paravascular Retinoschisis in High Myopia
High myopia (HM) is a severe form of nearsightedness characterized by a highly negative refractive error (usually -6 diopters or worse) and eye elongation.1 A meta-analysis conducted in 2010 reported a global prevalence of HM of 2.7% among individuals aged 15 and above.2 However, this prevalence is projected to increase in the coming decades, with an estimated 938 million people affected by HM by 2050, which would be approximately 9.8% of the global population.3 In HM patients, the progressive elongation of the eyeball can lead to various retinal abnormalities, such as myopic macular retinoschisis (MRS), characterized by t...
Source: American Journal of Ophthalmology - February 22, 2024 Category: Opthalmology Authors: Qing Zhao, Xinyu Zhao, Yan Luo, Zhikun Yang Tags: Original Articles Source Type: research
Comparison of the biometric characteristics after long term implantation of iris-fixated phakic intraocular lens in explanted and non-explanted groups of eyes
To evaluate and compare the biometric characteristics of the anterior chamber of a group of patients with significant endothelial cell loss (ECL) that required phakic IOL (pIOL) explantation and a group of patients who did not fulfill the explantation criteria related to corneal decompensation. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Luis Izquierdo, Fiorella Casanova Imken, Pablo Larco, Jose Chauca, Maria A. Henriquez Tags: Original Articles Source Type: research
Comment on Large Language Models in Ophthalmology Scientific Writing: Ethical Considerations, Blurred Lines or Not at All?1
Salimi and Saheb demonstrated the impressive capabilities of ChatGPT 3.5, a Large Language Model (LLM) that “co-authored” the opening 10 paragraphs of their article on the significant impacts and ethical problems with using LLMs in Ophthalmology scientific writing1. Our correspondence explores how the technical processes LLMs use to produce content are incompatible with the scientific method, research , and academic publishing. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Dr Alexander James Cameron Jessup, Professor Minas Theodore Coroneo Tags: Correspondence Source Type: research
Clinical Course and Visual Outcomes of Papilledema in Pediatric Cerebral Venous Sinus Thrombosis
In this study, we report on the natural history and visual outcomes of papilledema in children with CVST. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Jessica A. Sun, Tais Estrela, Ryan Gise Tags: Original Articles Source Type: research
Socioeconomic Disparities in Glaucoma Severity at Initial Diagnosis: A Nationwide EHR Cohort Analysis
To assess disparities in initial disease severity among open-angle glaucoma (OAG) patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Swarup S. Swaminathan, Felipe A. Medeiros Tags: Articles Source Type: research
Anterior chamber cholesterol crystals in stage 5C retinopathy of prematurity
A 1-year-old girl was referred for retinopathy of prematurity (ROP) with total retinal detachment and flat anterior chamber in her right eye (Figure A). The lens and preretinal fibrovascular tissue were then removed. Examination showed clear anterior chamber and open-funnel retina with subretinal cholesterol crystals six months after surgery (Figure, B). Five months later, sparkling substance was seen in the eye. Examination revealed anterior chamber sparkling crystals (Figure, C). A procedure of intraocular lavage was performed. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Huanyu Liu, Jie Peng, Peiquan Zhao Tags: Illustrations & Insights Source Type: research
Omidenepag Isopropyl Versus Timolol in Patients With Glaucoma or Ocular Hypertension: Two Randomized Phase 3 Trials (SPECTRUM 4 and 3)
Glaucoma refers to a group of optic nerve diseases associated with progressive vision loss and is one of the leading causes of irreversible blindness worldwide.1 Elevated intraocular pressure (IOP) is a key contributing factor for the progression of open-angle glaucoma (OAG) and ocular hypertension (OHT).2 IOP reduction remains a key goal for glaucoma therapy2 and reducing elevated IOP with ocular hypotensive medication has been demonstrated to delay disease progression.3-5 (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Jason Bacharach, Jacob W. Brubaker, David G. Evans, Fenghe Lu, Noriko Odani-Kawabata, Takaharu Yamabe, David L. Wirta Tags: Original Articles Source Type: research
Comment on “Large Language Models in Ophthalmology Scientific Writing: Ethical Considerations Blurred Lines or Not at All?”
In their paper, Salimi and Saheb1 describe possible applications of Large Language Models (LLMs) especially ChatGPT for scientific writing, including bibliographic research. Based on own studies and those of others2-5 this seems to be too optimistic. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Konradin Metze, Irene Lorand-Metze, Rosana C Morandin-Reis, Jo ão B Florindo Tags: Correspondence Source Type: research
Clinical Significance of Optic Disc Hemorrhage Size in Visual Field Progression in Glaucoma
To investigate the correlation between optic disc hemorrhage (DH) size and glaucoma progression. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Yoon Jeong, Eunoo Bak, Mirinae Jang, Ahnul Ha, Young In Shin, Min Gu Huh, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park Tags: Original Articles Source Type: research
Drug Approval for the Treatment of Geographic Atrophy: How We Got Here and Where We Need to Go
To discuss the clinical trial results leading to the FDA approval of anti-complement therapies for geographic atrophy (GA), perspectives on functional data from the GA clinical trials, and how lessons from the FDA approval may guide future directions for basic and clinical research in AMD. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 20, 2024 Category: Opthalmology Authors: Karl G Csaky, Jason ML Miller, Daniel F Martin, Mark W. Johnson Tags: Perspective Source Type: research
Association between sociodemographic factors and self-reported glaucoma in the National Health Interview Survey: a population-based analysis
To investigate the association between social determinants of health (SDH) in the domains of social and community context, education access, environmental context, economic stability, and healthcare access, with glaucoma prevalence. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 20, 2024 Category: Opthalmology Authors: Jim Xie, Nikhil S. Patil, Marko M. Popovic, Peter J. Kertes, Rajeev H. Muni, Matthew B. Schlenker, Iqbal Ike K. Ahmed, Radha P. Kohly Tags: Original Articles Source Type: research
Severe spontaneous tilt of scleral-fixated intraocular lenses
: To report and evaluate a multicenter series of 18 cases of severe, spontaneous IOL tilt involving the flanged intrascleral haptic fixation technique (FISHF). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 16, 2024 Category: Opthalmology Authors: Jennifer M Enright, Boonkit Purt, Brent Bruck, Parth Shah, Emily Eton, Sina Rezaei, Stephen Armenti, Kishan G Patel, James Liu, Angela Verkade, Abdualrahman Hamad, Thomas J Wubben, Arsham Sheybani, David Crandall, Bradford L Tannen, Grant M Comer, Shahzad Tags: Original Articles Source Type: research
Genetics, Clinical Characteristics, and Natural History of PDE6B-Associated Retinal Dystrophy
Retinitis pigmentosa (RP) (OMIM #268000) is the most common hereditary retinal disease. It is characterized by progressive retinal degeneration that causes symptoms of early nyctalopia and peripheral field constriction, eventually affecting the central vision and leading to legal blindness.1 One in 3-4000 in the population has RP, and it can be inherited as autosomal recessive in 50 –60% of cases, 30–40% as autosomal dominant and the remaining ∼5–15% as X-linked inheritance.2, 3 Non-syndromic RP has been associated with more than 80 genes, more than 35 which have been associated with an autosomal recessive mode of ...
Source: American Journal of Ophthalmology - February 16, 2024 Category: Opthalmology Authors: Shaima Awadh Hashem, Michalis Georgiou, Yu Fujinami-Yokokawa, Yannik Laich, Malena Daich Varela, Thales A.C. de Guimaraes, Naser Ali, Omar A. Mahroo, Andrew R. Webster, Kaoru Fujinami, Michel Michaelides Tags: Original Articles Source Type: research
Incidence and Outcomes of Eye Trauma Associated with Recreative Use of Non-Powder Toy-Guns: a 12-years retrospective study
A recent study reported that non-powder toy-guns (NPTG) were responsible for 8,630 ocular injuries in patients of 0 to 20 years old in the United States between 2000 and 20191. While this publication provides an interesting overview of the demographics of these injuries, detailed data on the projectile involved and its influence on the ophthalmological outcomes is lacking2. Paintball guns, air guns, BB/airsoft guns, foam bullets and/or foam darts blasters have distinct operating mechanisms, and various projectile designs and do not follow the same regulations and/or age-labelling. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - February 16, 2024 Category: Opthalmology Authors: Alexandre DENTEL, Etienne BOULANGER, Thibaut CHAPRON, Lucile SENICOURT, Florence METGE, Pascal DUREAU, Catherine VIGNAL-CLERMONT, Georges CAPUTO, Gilles C. MARTIN Tags: Original Articles Source Type: research
