The Role of Osteogenic Effect and Vascular Function in Bone Health in Hypertensive Rats: A Study of Anti-hypertensive and Hemorheologic Drugs
This study demonstrates the importance of vascular function in addition to increased bone mass for improving bone health as achieved by PTX without affecting BP, and suggests a promising treatment option for osteoporosis in hypertensive patients, particularly at-risk postmenopausal women. (Source: Calcified Tissue International)
Source: Calcified Tissue International - December 15, 2023 Category: Orthopaedics Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Dermato-Venereologica - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Derm Venereol A... - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Dermato-Venereologica - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Derm Venereol A... - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Dermato-Venereologica - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Off-label Prescription in Paediatric Dermatology: A Retrospective Observational Study in a Tertiary Hospital
Acta Derm Venereol. 2023 Dec 11;103:adv11937. doi: 10.2340/actadv.v102.11937.ABSTRACTOff-label prescription in paediatric patients is common, where some studies indicate that dermatological conditions are more prone to off-label treatment. This is the first study to analyse the prevalence of off-label prescription in paediatric dermatology consultation. This retrospective observational study was performed using the medical records of paediatric patients who were evaluated in a paediatric dermatological consultation in Pontevedra University Hospital, Pontevedra, Spain. Of the 468 patients reviewed, 186 prescriptions were is...
Source: Acta Derm Venereol A... - December 11, 2023 Category: Dermatology Authors: Carmen Couselo-Rodr íguez Ana Batalla Sandra Mart ínez-Fernández Carmela D ávila-Pousa Diego Soto-Garc ía Luc ía Vilanova-Trillo Ángeles Flórez Source Type: research
Efficacy and Safety of the Travoprost Intraocular Implant in Reducing Topical IOP-Lowering Medication Burden in Patients with Open-Angle Glaucoma or Ocular Hypertension
ConclusionThe travoprost intraocular implant demonstrated robust IOP-lowering and substantially reduced topical IOP-lowering medication burden for up to 36 months following a single administration, while maintaining a favorable safety profile. The travoprost intraocular implant promises to be a meaningful addition to the interventional glaucoma armamentarium by addressing the key shortcomings of topical IOP-lowering medications, including low adherence and topical side effects while controlling IOP for up to 36 months.Trial RegistryClinicalTrials.gov identifier NCT02754596 registered 28 April 2016. (Source: Drugs)
Source: Drugs - December 7, 2023 Category: Drugs & Pharmacology Source Type: research
Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis
AbstractPurpose of ReviewTo analyze and compare the effects of epistaxis treatments for Hereditary Hemorrhagic Telangiectasia (HHT) patients.Recent FindingsOf total of 21 randomized controlled trials (RCT), the data from 15 RCTs (697 patients, 7 treatments: timolol, propranolol, bevacizumab, doxycycline, tacrolimus, estriol/estradiol, and tranexamic acid) were pooled for the meta-analyses while the other 6 studies (treatments: electrosurgical plasma coagulation, KTP laser, postoperative packing, tamoxifen, sclerosing agent, and estriol) were reviewed qualitatively. When compared to placebo, propranolol offered the most imp...
Source: Current Allergy and Asthma Reports - November 23, 2023 Category: Allergy & Immunology Source Type: research
Efficacy of timolol in the treatment of facial hemangioma and its effect on the proliferation and apoptosis of hemangioma stem cells
In conclusion, Timolol can effectively treat facial hemangioma in children, inhibit the proliferation of hemangioma stem cells and promote their apoptosis, with good curative effect, short treatment time and no obvious adverse reactions and it is economical and easy to accept.PMID:37953576 | DOI:10.14715/cmb/2023.69.10.16 (Source: Cellular and Molecular Biology)
Source: Cellular and Molecular Biology - November 13, 2023 Category: Molecular Biology Authors: Hongjian Zhu Hua Luo Wenjuan Lai Source Type: research
Efficacy of timolol in the treatment of facial hemangioma and its effect on the proliferation and apoptosis of hemangioma stem cells
In conclusion, Timolol can effectively treat facial hemangioma in children, inhibit the proliferation of hemangioma stem cells and promote their apoptosis, with good curative effect, short treatment time and no obvious adverse reactions and it is economical and easy to accept.PMID:37953576 | DOI:10.14715/cmb/2023.69.10.16 (Source: Mol Biol Cell)
Source: Mol Biol Cell - November 13, 2023 Category: Molecular Biology Authors: Hongjian Zhu Hua Luo Wenjuan Lai Source Type: research
Efficacy of timolol in the treatment of facial hemangioma and its effect on the proliferation and apoptosis of hemangioma stem cells
In conclusion, Timolol can effectively treat facial hemangioma in children, inhibit the proliferation of hemangioma stem cells and promote their apoptosis, with good curative effect, short treatment time and no obvious adverse reactions and it is economical and easy to accept.PMID:37953576 | DOI:10.14715/cmb/2023.69.10.16 (Source: Cellular and Molecular Biology)
Source: Cellular and Molecular Biology - November 13, 2023 Category: Molecular Biology Authors: Hongjian Zhu Hua Luo Wenjuan Lai Source Type: research
Efficacy of timolol in the treatment of facial hemangioma and its effect on the proliferation and apoptosis of hemangioma stem cells
In conclusion, Timolol can effectively treat facial hemangioma in children, inhibit the proliferation of hemangioma stem cells and promote their apoptosis, with good curative effect, short treatment time and no obvious adverse reactions and it is economical and easy to accept.PMID:37953576 | DOI:10.14715/cmb/2023.69.10.16 (Source: Mol Biol Cell)
Source: Mol Biol Cell - November 13, 2023 Category: Molecular Biology Authors: Hongjian Zhu Hua Luo Wenjuan Lai Source Type: research
