Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis
Skinmed. 2022 Feb 28;20(1):69-71. eCollection 2022.ABSTRACTA 25-year-old man consulted us with a severe exacerbation of pustular psoriasis for 10 days (Figure 1). The patient had pustular psoriasis for the last 12 years. During his hospital stay, he suffered sudden painless and profound loss of vision in both eyes. Subsequently, he was referred to an ophthalmologist. Slit lamp examination of both eyes revealed the presence of a clot in anterior chamber with neovascularization of the iris and the fibrovascular membrane covering the pupil and iris bombe formation nasally and inferiorly (Figure 2a). B-scan ultrasonography sho...
Source: Skinmed - April 18, 2022 Category: Dermatology Authors: Geetika Chhabra Prashant Verma Anju Nagar Source Type: research
Treatment of open-angle glaucoma and ocular hypertension with preservative-free tafluprost/timolol fixed-dose combination therapy: 6 case reports and clinical outcomes
Treatment of open angle glaucoma (OAG) and/or ocular hypertension (OHT) focuses on achievement of target intraocular pressure (IOP), with the objective of slowing disease progression. However, ocular surface h... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - April 2, 2022 Category: Opthalmology Authors: E. Ansari, S. Chappiti, J. Pavicic-Astalos, J. C. Pinto-Bonilla, I. Riva, M. Sacchi and F. Sa énz-Francés Tags: Case report Source Type: research
Topical ophthalmic beta-blockers are associated with ocular pseudopemphigoid: A pharmacovigilance study of antiglaucoma medications utilising the FDA adverse event reporting system
CONCLUSIONS: Our findings support an association between OPP and antiglaucoma medications; under the most stringent control for topical irritant/preservative effect by of comparison to topical eye drops, unoprostone, carteolol, betaxolol and timolol all had a significant ROR for OPP.PMID:35316535 | DOI:10.1111/ajd.13828 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - March 22, 2022 Category: Dermatology Authors: Patrick Michael Jedlowski Mahdieh Fazel Jedlowski Source Type: research
Topical ophthalmic beta-blockers are associated with ocular pseudopemphigoid: A pharmacovigilance study of antiglaucoma medications utilising the FDA adverse event reporting system
CONCLUSIONS: Our findings support an association between OPP and antiglaucoma medications; under the most stringent control for topical irritant/preservative effect by of comparison to topical eye drops, unoprostone, carteolol, betaxolol and timolol all had a significant ROR for OPP.PMID:35316535 | DOI:10.1111/ajd.13828 (Source: The Australasian Journal of Dermatology)
Source: The Australasian Journal of Dermatology - March 22, 2022 Category: Dermatology Authors: Patrick Michael Jedlowski Mahdieh Fazel Jedlowski Source Type: research
Molecules, Vol. 27, Pages 1938: The Effect of Beta Adrenoreceptor Blockers on Viability and Cell Colony Formation of Non-Small Cell Lung Cancer Cell Lines A549 and H1299
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Beta adrenoblockers are a large class of drugs used to treat cardiovascular diseases, migraines, glaucoma and hyperthyroidism. Over the last couple of decades, the anticancer effects of these compounds have been extensively studied. However, the exact mechanism is still not known, and more detailed studies are required. The aim of our study was to evaluate the anticancer activity of beta adrenoblockers in non-small cell lung cancer cell lines A549 and H1299. In order to find the relationship with their selectivity to beta adrenoreceptors, selective (atenolol, betaxolol, esmolol, metoprolol) and non-selective (pindol...
Source: Molecules - March 17, 2022 Category: Chemistry Authors: Marina Sidorova Vilma Petrikait ė Tags: Article Source Type: research
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: Results from the VISIONARY Study Population in Spain
Journal of Ocular Pharmacology and Therapeutics, Ahead of Print. (Source: Journal of Ocular Pharmacology and Therapeutics)
Source: Journal of Ocular Pharmacology and Therapeutics - February 28, 2022 Category: Opthalmology Authors: Jose J. Garcia-Medina Javier Benitez-del-Castillo I ñaki Rodríguez-Agirretxe Fernando Lopez-Lopez Antonio Moreno-Valladares Source Type: research
Infantile Hemangioma: A Current Review
Infantile hemangiomas (IHs) are common vascular lesions which are benign but can cause significant functional and cosmetic morbidity. Since the fortuitous discovery of propranolol being effective to treat IH over a decade ago, the therapy and prognosis for children with IH have improved dramatically. Oral propranolol (as well as other oral beta-blockers and topical timolol) are safe and effective treatments, and have now supplanted other therapies. Making the correct diagnosis is crucial, because other vascular lesions can mimic IH. In addition, IH can be the first manifestation of an underlying syndrome. For IH requiring ...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Review Article Source Type: research
Topical timolol enhances lower leg surgical wound healing in elderly patients with comorbidities: A retrospective review
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 16, 2022 Category: Dermatology Authors: Rachel Manci, Zaeem H. Nazir, Stephen W. Dusza, Chih-Shan Jason Chen Source Type: research
Topical timolol enhances surgical wound healing in the lower portion of the leg in older patients with comorbidities: A retrospective review
In this study, we evaluated timolol's efficacy to improve secondary intention wound h ealing in surgical wounds below the knee in patients at risk of prolonged wound healing. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 16, 2022 Category: Dermatology Authors: Rachel Manci, Zaeem H. Nazir, Stephen W. Dusza, Chih-Shan Jason Chen Tags: Research letter Source Type: research
Combination product of dermal matrix, preconditioned human mesenchymal stem cells and timolol promotes wound healing in the porcine wound model
Applying a combination treatment as shown in steps 1 –3, MSCs preconditioned in timolol at hypoxia on wound scaffolds (MSC-scaffold) with daily topical timolol solution to wounds, improves wound healing in a porcine model. The treatment promotes reepithelialization in the excisional wounds by 40.2% and increases angiogenesis by elevating CD31 immuno staining compared with the control, while the accumulated timolol concentration detected in plasma remains below the clinically safe level of 0.3 ng/mL after the 15-day course of treatment. AbstractA combination product of human mesenchymal stem/stromal cells (MSCs) embedded...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - January 31, 2022 Category: Materials Science Authors: Hsin ‐ya Yang,
Fernando Fierro,
Daniel J. Yoon,
Anthony Gallegos,
Stephanie L. Osborn,
Alan V. Nguyen,
Thomas R. Peavy,
William Ferrier,
Linda Talken,
Betty W. Ma,
Kristopher G. Galang,
Andrea Medina Lopez,
Daniel R. Fregoso,
Heather Stewar Tags: RESEARCH ARTICLE Source Type: research
