Otto Warburg < em > versus < /em > Molecular Biologists: Who Is Correct About Human Carcinogenesis, and Why Does It Matter to Dermatologists?
Skinmed. 2021 Dec 1;19(6):412-413. eCollection 2021.NO ABSTRACTPMID:35022110 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: W Clark Lambert Thu M Truong Claude E Gagna Muriel W Lambert Michael Lea Source Type: research

Resveratrol as a Skincare Ingredient: Current Evidence and the Future Potential
Skinmed. 2021 Dec 1;19(6):414-416. eCollection 2021.ABSTRACTResveratrol is a compound found abundantly in grapes' skin and red wine. It has recently become an increasingly popular ingredient of cosmeceuticals due to its reported anti-aging properties and inhibiting effects on melanogenesis. When compared to synthetic chemicals, natural ingredients, such as resveratrol, are often less expensive to produce and more widely available, which make them an attractive additive to skincare formulations. As resveratrol continues to gain commercial popularity, we reviewed the current literature regarding its background, biochemical m...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Cameron M Zachary Jordan V Wang Nazanin Saedi Source Type: research

Noncultured Epidermal Suspension in Vitiligo-A Review of Origins, Modifications, and Innovations for this Surgical Masterstroke!
Skinmed. 2021 Dec 1;19(6):419-423. eCollection 2021.ABSTRACTVitiligo, a disorder of depigmentation, has a profound psychosocial burden. Surgical techniques using transplantation of tissue grafts or melanocytes have long been used to correct vitiliginous macules, often utilizing noncultured epidermal suspension. This procedure has undergone a remarkable transformation from its original methods in terms of preparation of recipient site, concentration and separation of melanocytes, incubation, and cryofreezing.Vitiligo is an acquired hypomelanotic disorder characterized by depigmented and circumscribed macules or patches, wit...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Madhulika Mhatre Aseem Sharma Sahana Srihari Mohamad Goldust Source Type: research

Efficacy and Tolerability of a Procedure Enhancement System with TriHex Technology < sup > ® < /sup > as a Pre- and Post-Radiofrequency Microneedling Regimen
Skinmed. 2021 Dec 1;19(6):426-431. eCollection 2021.ABSTRACTPostoperative recovery is an important consideration for patients planning dermal rejuvenation procedures. A topical procedure enhancement system (PES) containing a tripeptide and hexapeptide (TriHex Technology®; Alastin Skincare®, Carlsbad, CA) hastens recovery from facial rejuvenation procedures, such as laser resurfacing. We assessed the efficacy and tolerability of the PES compared to a standard-of-care antioxidant regimen for improving recovery following three monthly facial radiofrequency (RF) microneedling treatments. Assessments included grading pr...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Jennifer A Croix Shannon Hernandez Jennifer Chwalek Robyn Gmyrek Anne Chapas Source Type: research

Anemia in Patients with Hidradenitis Suppurativa: Prevalence and Risk Factors in a Hospital-Based Cohort
We examined the prevalence and risk factors of anemia in patients with hidradenitis suppurativa (HS). The presence of anemia and information on risk factors was obtained through interview, clinical examination, and blood samples in a cohort of 367 consecutive patients with HS. The overall prevalence of anemia was 9.3% (11.4% in men and 8.1% in women). Altogether 7.9%, 7.0%, and 20.4% of patients with Hurley stage I, II, and III were anemic, respectively. Risk factors for anemia included increasing age, nonwhite ethnicity, sporadic (nonfamilial) HS, concomitant inflammatory bowel disease (IBD), absence of hypertension, and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Astrid-Helene Ravn J ørgensen Valdemar Wendelboe Nielsen Yiqiu Yao Hans Christian Ring Simon Francis Thomsen Source Type: research

Impact of Psoriasis on Quality of Life: A Qualitative Study Focused on Patient Perspectives
Skinmed. 2021 Dec 1;19(6):438-439. eCollection 2021.ABSTRACTPsoriasis is a chronic skin condition that can affect any part of the body, is often present in visible areas, and may occasionally be difficult to treat. Psoriasis can lead to depression and decreased quality of life. We performed a qualitative survey to examine patient perspectives on how psoriasis impacts their lives. Patients with psoriasis are vulnerable to embarrassment and stigmatization in public spaces, as well as discrimination at work, school, or in society. Further studies are needed to determine the best interventions for improving the quality of life...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Elizabeth Schoenberg Jordan V Wang Matthew Keller Source Type: research

Clinical Patterns and Clinicopathologic Correlation of 100 Patients with Erythroderma in a Tertiary Care Institute in India
Skinmed. 2021 Dec 1;19(6):440-450. eCollection 2021.ABSTRACTErythroderma is a severe dermatologic manifestation of a variety of diseases. We analyzed the clinical parameters and the clinicopathologic correlation in patients with erythroderma. Consecutive patients diagnosed with erythroderma at a tertiary care institute were evaluated for 5 years. Detailed history and clinical examination were noted along with extensive hematologic and biochemical investigations, radiologic studies, and skin biopsy for histopathologic examination, and if required, for immunoflourescence and immunohistochemistry; 83 men and 17 women were inc...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Rahul Mahajan Sunil Dogra Mousumi Roy Bandyopadhyay Uma Nahar Saikia Amrinder Jit Kanwar Source Type: research

Dermatofibrosarcoma Protuberans: A Dermatologic/dermatopathologic "Snake in the Grass"
Skinmed. 2021 Dec 1;19(6):452-455. eCollection 2021.NO ABSTRACTPMID:35022117 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Albert Alhatem Alyssa Swearingen Muriel W Lambert Rohan Shah Britney Wilson Robert A Schwartz W Clark Lambert Source Type: research

Dermatoscopic Patterns in Pellagra
Skinmed. 2021 Dec 1;19(6):456-457. eCollection 2021.NO ABSTRACTPMID:35022118 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Houda Hammami Samy Fenniche Source Type: research

Comedonal Lupus: An Unusual Presentation of Chronic Cutaneous Lupus Erythematosus
Skinmed. 2021 Dec 1;19(6):458-459. eCollection 2021.NO ABSTRACTPMID:35022119 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Fatma Hammami Emna Bahloul Abderrahmen Masmoudi Sonia Boudaya Meriem Amouri Hamida Turki Source Type: research

Cutaneous Desmoplastic Leiomyosarcoma Development at Smallpox Vaccination Site
Skinmed. 2021 Dec 1;19(6):462-463. eCollection 2021.ABSTRACTAn 81-year-old man presented to the clinic with a 2.1 cm firm, skin-colored subcutaneous tumor on the left upper arm (Figure 1). The lesion arose at the site of a past smallpox vaccination and had been slowly enlarging for approximately 4 years. The differential diagnosis included sympastic leiomyoma, and a variety of desmoplastic spindle cell lesions such as desmoplastic melanoma, cutaneous spindle cell carcinoma, and desmoplastic leiomyosarcoma. Punch biopsy and immunohistochemical staining revealed positive spindle cells for desmin and caldesmon (Figures 2 and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Meera H Patel Caitlin M Brumfiel David Glembocki Adam J Luber Source Type: research

Anetoderma in a Patient with Newly Diagnosed Hodgkin's Lymphoma
Skinmed. 2021 Dec 1;19(6):464-465. eCollection 2021.ABSTRACTA previously healthy 28-year-old woman was admitted to the hospital with respiratory failure and was found to have significant lymphadenopathy on her CT scan. A lymph node biopsy was performed; the pathology was consistent with a diagnosis of Hodgkin's lymphoma and the patient was noted to have multiple, wrinkled, nonscaly, oval-shaped papules that were easily compressible (Figure 1) and were present on the upper and lower extremities, abdomen, chest, and back. The lesions were entirely asymptomatic and had first developed 1 year prior to presentation. Since their...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Soniya Pateriya Nitin Tiwari Jeanne Young Source Type: research

Diffuse Large B-Cell Lymphoma in the Setting of Chronic Lymphocytic Leukemia
Skinmed. 2021 Dec 1;19(6):466-470. eCollection 2021.ABSTRACTA 77-year-old man was referred to our department with a 6-month history of a painless, rapidly enlarging tumor on the left leg. Fourteen years ago, he was diagnosed with chronic lymphocytic leukemia (CLL), and he had presented with lymphocytosis and multiple lymphadenopathies (Rai stage II). Both bone marrow aspiration and peripheral blood immunophenotyping identified a monoclonal B-cell population expressing surface CD5, CD20, CD23, CD43, and IgG kappa. At that time, he underwent eight courses of treatment with oral fludarabine, followed by complete remission, an...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Mariana Esteves Teresa Baudrier Ana Carneiro Filomena Azevedo Alberto Mota Source Type: research

Dupilumab for the Treatment of Actinic Prurigo
Skinmed. 2021 Dec 1;19(6):471-472. eCollection 2021.ABSTRACTA 42-year-old Latino man with a medical history of vitiligo presented to our outpatient clinic with a 25-year history of a recurrent, itchy eruption on his face and hands. Physical examination revealed pink, scaly, erythematous, lichenified papules and plaques with overlying crusts, photodistributed on the nose, chin, cheeks, hands, and ears (Figures 1a and 2a). The lips were edematous with hemorrhagic crusting, and conjunctival injection and partial corneal opacities were noted (Figures 1b-1c). Histologic evaluation demonstrated psoriasiform hyperplasia with hype...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Allison M Perz Bilal Fawaz Tia Pyle Niraj Butala Justin J Green Source Type: research

Efficacy of Ablative Fractional CO2 Laser in the Treatment of a Cutaneous Leishmaniasis Scar
Skinmed. 2021 Dec 1;19(6):475-480. eCollection 2021.NO ABSTRACTPMID:35022124 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Amal Chamli Houda Hammami Samy Fenniche Source Type: research

Cochlear Implant-Induced Contact Dermatitis
Skinmed. 2021 Dec 1;19(6):477-480. eCollection 2021.NO ABSTRACTPMID:35022125 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Antonella Tammaro Ganiyat Adenike Ralitsa Adebanjo Francesca Romana Parisella Camilla Chello Francesca Magri Alvise Sernicola Edoardo Covelli Simonetta Monini Maurizio Barbara Source Type: research

Zosteriform Pattern of Cutaneous Metastasis from Breast Cancer: A Rare Clinical Variant
Skinmed. 2021 Dec 1;19(6):478-480. eCollection 2021.NO ABSTRACTPMID:35022126 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Youssef Monia Soua Yosra Korbi Mouna Hadhri Rim Ben Brahim Hajer Belhadjali Hichem Zili Jameleddine Source Type: research

Otto Warburg < em > versus < /em > Molecular Biologists: Who Is Correct About Human Carcinogenesis, and Why Does It Matter to Dermatologists?
Skinmed. 2021 Dec 1;19(6):412-413. eCollection 2021.NO ABSTRACTPMID:35022110 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: W Clark Lambert Thu M Truong Claude E Gagna Muriel W Lambert Michael Lea Source Type: research

Resveratrol as a Skincare Ingredient: Current Evidence and the Future Potential
Skinmed. 2021 Dec 1;19(6):414-416. eCollection 2021.ABSTRACTResveratrol is a compound found abundantly in grapes' skin and red wine. It has recently become an increasingly popular ingredient of cosmeceuticals due to its reported anti-aging properties and inhibiting effects on melanogenesis. When compared to synthetic chemicals, natural ingredients, such as resveratrol, are often less expensive to produce and more widely available, which make them an attractive additive to skincare formulations. As resveratrol continues to gain commercial popularity, we reviewed the current literature regarding its background, biochemical m...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Cameron M Zachary Jordan V Wang Nazanin Saedi Source Type: research

Noncultured Epidermal Suspension in Vitiligo-A Review of Origins, Modifications, and Innovations for this Surgical Masterstroke!
Skinmed. 2021 Dec 1;19(6):419-423. eCollection 2021.ABSTRACTVitiligo, a disorder of depigmentation, has a profound psychosocial burden. Surgical techniques using transplantation of tissue grafts or melanocytes have long been used to correct vitiliginous macules, often utilizing noncultured epidermal suspension. This procedure has undergone a remarkable transformation from its original methods in terms of preparation of recipient site, concentration and separation of melanocytes, incubation, and cryofreezing.Vitiligo is an acquired hypomelanotic disorder characterized by depigmented and circumscribed macules or patches, wit...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Madhulika Mhatre Aseem Sharma Sahana Srihari Mohamad Goldust Source Type: research

Efficacy and Tolerability of a Procedure Enhancement System with TriHex Technology < sup > ® < /sup > as a Pre- and Post-Radiofrequency Microneedling Regimen
Skinmed. 2021 Dec 1;19(6):426-431. eCollection 2021.ABSTRACTPostoperative recovery is an important consideration for patients planning dermal rejuvenation procedures. A topical procedure enhancement system (PES) containing a tripeptide and hexapeptide (TriHex Technology®; Alastin Skincare®, Carlsbad, CA) hastens recovery from facial rejuvenation procedures, such as laser resurfacing. We assessed the efficacy and tolerability of the PES compared to a standard-of-care antioxidant regimen for improving recovery following three monthly facial radiofrequency (RF) microneedling treatments. Assessments included grading pr...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Jennifer A Croix Shannon Hernandez Jennifer Chwalek Robyn Gmyrek Anne Chapas Source Type: research

Anemia in Patients with Hidradenitis Suppurativa: Prevalence and Risk Factors in a Hospital-Based Cohort
We examined the prevalence and risk factors of anemia in patients with hidradenitis suppurativa (HS). The presence of anemia and information on risk factors was obtained through interview, clinical examination, and blood samples in a cohort of 367 consecutive patients with HS. The overall prevalence of anemia was 9.3% (11.4% in men and 8.1% in women). Altogether 7.9%, 7.0%, and 20.4% of patients with Hurley stage I, II, and III were anemic, respectively. Risk factors for anemia included increasing age, nonwhite ethnicity, sporadic (nonfamilial) HS, concomitant inflammatory bowel disease (IBD), absence of hypertension, and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Astrid-Helene Ravn J ørgensen Valdemar Wendelboe Nielsen Yiqiu Yao Hans Christian Ring Simon Francis Thomsen Source Type: research

Impact of Psoriasis on Quality of Life: A Qualitative Study Focused on Patient Perspectives
Skinmed. 2021 Dec 1;19(6):438-439. eCollection 2021.ABSTRACTPsoriasis is a chronic skin condition that can affect any part of the body, is often present in visible areas, and may occasionally be difficult to treat. Psoriasis can lead to depression and decreased quality of life. We performed a qualitative survey to examine patient perspectives on how psoriasis impacts their lives. Patients with psoriasis are vulnerable to embarrassment and stigmatization in public spaces, as well as discrimination at work, school, or in society. Further studies are needed to determine the best interventions for improving the quality of life...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Elizabeth Schoenberg Jordan V Wang Matthew Keller Source Type: research

Clinical Patterns and Clinicopathologic Correlation of 100 Patients with Erythroderma in a Tertiary Care Institute in India
Skinmed. 2021 Dec 1;19(6):440-450. eCollection 2021.ABSTRACTErythroderma is a severe dermatologic manifestation of a variety of diseases. We analyzed the clinical parameters and the clinicopathologic correlation in patients with erythroderma. Consecutive patients diagnosed with erythroderma at a tertiary care institute were evaluated for 5 years. Detailed history and clinical examination were noted along with extensive hematologic and biochemical investigations, radiologic studies, and skin biopsy for histopathologic examination, and if required, for immunoflourescence and immunohistochemistry; 83 men and 17 women were inc...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Rahul Mahajan Sunil Dogra Mousumi Roy Bandyopadhyay Uma Nahar Saikia Amrinder Jit Kanwar Source Type: research

Dermatofibrosarcoma Protuberans: A Dermatologic/dermatopathologic "Snake in the Grass"
Skinmed. 2021 Dec 1;19(6):452-455. eCollection 2021.NO ABSTRACTPMID:35022117 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Albert Alhatem Alyssa Swearingen Muriel W Lambert Rohan Shah Britney Wilson Robert A Schwartz W Clark Lambert Source Type: research

Dermatoscopic Patterns in Pellagra
Skinmed. 2021 Dec 1;19(6):456-457. eCollection 2021.NO ABSTRACTPMID:35022118 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Houda Hammami Samy Fenniche Source Type: research

Comedonal Lupus: An Unusual Presentation of Chronic Cutaneous Lupus Erythematosus
Skinmed. 2021 Dec 1;19(6):458-459. eCollection 2021.NO ABSTRACTPMID:35022119 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Fatma Hammami Emna Bahloul Abderrahmen Masmoudi Sonia Boudaya Meriem Amouri Hamida Turki Source Type: research

Cutaneous Desmoplastic Leiomyosarcoma Development at Smallpox Vaccination Site
Skinmed. 2021 Dec 1;19(6):462-463. eCollection 2021.ABSTRACTAn 81-year-old man presented to the clinic with a 2.1 cm firm, skin-colored subcutaneous tumor on the left upper arm (Figure 1). The lesion arose at the site of a past smallpox vaccination and had been slowly enlarging for approximately 4 years. The differential diagnosis included sympastic leiomyoma, and a variety of desmoplastic spindle cell lesions such as desmoplastic melanoma, cutaneous spindle cell carcinoma, and desmoplastic leiomyosarcoma. Punch biopsy and immunohistochemical staining revealed positive spindle cells for desmin and caldesmon (Figures 2 and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Meera H Patel Caitlin M Brumfiel David Glembocki Adam J Luber Source Type: research

Anetoderma in a Patient with Newly Diagnosed Hodgkin's Lymphoma
Skinmed. 2021 Dec 1;19(6):464-465. eCollection 2021.ABSTRACTA previously healthy 28-year-old woman was admitted to the hospital with respiratory failure and was found to have significant lymphadenopathy on her CT scan. A lymph node biopsy was performed; the pathology was consistent with a diagnosis of Hodgkin's lymphoma and the patient was noted to have multiple, wrinkled, nonscaly, oval-shaped papules that were easily compressible (Figure 1) and were present on the upper and lower extremities, abdomen, chest, and back. The lesions were entirely asymptomatic and had first developed 1 year prior to presentation. Since their...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Soniya Pateriya Nitin Tiwari Jeanne Young Source Type: research

Diffuse Large B-Cell Lymphoma in the Setting of Chronic Lymphocytic Leukemia
Skinmed. 2021 Dec 1;19(6):466-470. eCollection 2021.ABSTRACTA 77-year-old man was referred to our department with a 6-month history of a painless, rapidly enlarging tumor on the left leg. Fourteen years ago, he was diagnosed with chronic lymphocytic leukemia (CLL), and he had presented with lymphocytosis and multiple lymphadenopathies (Rai stage II). Both bone marrow aspiration and peripheral blood immunophenotyping identified a monoclonal B-cell population expressing surface CD5, CD20, CD23, CD43, and IgG kappa. At that time, he underwent eight courses of treatment with oral fludarabine, followed by complete remission, an...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Mariana Esteves Teresa Baudrier Ana Carneiro Filomena Azevedo Alberto Mota Source Type: research

Dupilumab for the Treatment of Actinic Prurigo
Skinmed. 2021 Dec 1;19(6):471-472. eCollection 2021.ABSTRACTA 42-year-old Latino man with a medical history of vitiligo presented to our outpatient clinic with a 25-year history of a recurrent, itchy eruption on his face and hands. Physical examination revealed pink, scaly, erythematous, lichenified papules and plaques with overlying crusts, photodistributed on the nose, chin, cheeks, hands, and ears (Figures 1a and 2a). The lips were edematous with hemorrhagic crusting, and conjunctival injection and partial corneal opacities were noted (Figures 1b-1c). Histologic evaluation demonstrated psoriasiform hyperplasia with hype...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Allison M Perz Bilal Fawaz Tia Pyle Niraj Butala Justin J Green Source Type: research

Efficacy of Ablative Fractional CO2 Laser in the Treatment of a Cutaneous Leishmaniasis Scar
Skinmed. 2021 Dec 1;19(6):475-480. eCollection 2021.NO ABSTRACTPMID:35022124 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Amal Chamli Houda Hammami Samy Fenniche Source Type: research

Cochlear Implant-Induced Contact Dermatitis
Skinmed. 2021 Dec 1;19(6):477-480. eCollection 2021.NO ABSTRACTPMID:35022125 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Antonella Tammaro Ganiyat Adenike Ralitsa Adebanjo Francesca Romana Parisella Camilla Chello Francesca Magri Alvise Sernicola Edoardo Covelli Simonetta Monini Maurizio Barbara Source Type: research

Zosteriform Pattern of Cutaneous Metastasis from Breast Cancer: A Rare Clinical Variant
Skinmed. 2021 Dec 1;19(6):478-480. eCollection 2021.NO ABSTRACTPMID:35022126 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Youssef Monia Soua Yosra Korbi Mouna Hadhri Rim Ben Brahim Hajer Belhadjali Hichem Zili Jameleddine Source Type: research

Otto Warburg < em > versus < /em > Molecular Biologists: Who Is Correct About Human Carcinogenesis, and Why Does It Matter to Dermatologists?
Skinmed. 2021 Dec 1;19(6):412-413. eCollection 2021.NO ABSTRACTPMID:35022110 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: W Clark Lambert Thu M Truong Claude E Gagna Muriel W Lambert Michael Lea Source Type: research

Resveratrol as a Skincare Ingredient: Current Evidence and the Future Potential
Skinmed. 2021 Dec 1;19(6):414-416. eCollection 2021.ABSTRACTResveratrol is a compound found abundantly in grapes' skin and red wine. It has recently become an increasingly popular ingredient of cosmeceuticals due to its reported anti-aging properties and inhibiting effects on melanogenesis. When compared to synthetic chemicals, natural ingredients, such as resveratrol, are often less expensive to produce and more widely available, which make them an attractive additive to skincare formulations. As resveratrol continues to gain commercial popularity, we reviewed the current literature regarding its background, biochemical m...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Cameron M Zachary Jordan V Wang Nazanin Saedi Source Type: research

Noncultured Epidermal Suspension in Vitiligo-A Review of Origins, Modifications, and Innovations for this Surgical Masterstroke!
Skinmed. 2021 Dec 1;19(6):419-423. eCollection 2021.ABSTRACTVitiligo, a disorder of depigmentation, has a profound psychosocial burden. Surgical techniques using transplantation of tissue grafts or melanocytes have long been used to correct vitiliginous macules, often utilizing noncultured epidermal suspension. This procedure has undergone a remarkable transformation from its original methods in terms of preparation of recipient site, concentration and separation of melanocytes, incubation, and cryofreezing.Vitiligo is an acquired hypomelanotic disorder characterized by depigmented and circumscribed macules or patches, wit...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Madhulika Mhatre Aseem Sharma Sahana Srihari Mohamad Goldust Source Type: research

Efficacy and Tolerability of a Procedure Enhancement System with TriHex Technology < sup > ® < /sup > as a Pre- and Post-Radiofrequency Microneedling Regimen
Skinmed. 2021 Dec 1;19(6):426-431. eCollection 2021.ABSTRACTPostoperative recovery is an important consideration for patients planning dermal rejuvenation procedures. A topical procedure enhancement system (PES) containing a tripeptide and hexapeptide (TriHex Technology®; Alastin Skincare®, Carlsbad, CA) hastens recovery from facial rejuvenation procedures, such as laser resurfacing. We assessed the efficacy and tolerability of the PES compared to a standard-of-care antioxidant regimen for improving recovery following three monthly facial radiofrequency (RF) microneedling treatments. Assessments included grading pr...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Jennifer A Croix Shannon Hernandez Jennifer Chwalek Robyn Gmyrek Anne Chapas Source Type: research

Anemia in Patients with Hidradenitis Suppurativa: Prevalence and Risk Factors in a Hospital-Based Cohort
We examined the prevalence and risk factors of anemia in patients with hidradenitis suppurativa (HS). The presence of anemia and information on risk factors was obtained through interview, clinical examination, and blood samples in a cohort of 367 consecutive patients with HS. The overall prevalence of anemia was 9.3% (11.4% in men and 8.1% in women). Altogether 7.9%, 7.0%, and 20.4% of patients with Hurley stage I, II, and III were anemic, respectively. Risk factors for anemia included increasing age, nonwhite ethnicity, sporadic (nonfamilial) HS, concomitant inflammatory bowel disease (IBD), absence of hypertension, and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Astrid-Helene Ravn J ørgensen Valdemar Wendelboe Nielsen Yiqiu Yao Hans Christian Ring Simon Francis Thomsen Source Type: research

Impact of Psoriasis on Quality of Life: A Qualitative Study Focused on Patient Perspectives
Skinmed. 2021 Dec 1;19(6):438-439. eCollection 2021.ABSTRACTPsoriasis is a chronic skin condition that can affect any part of the body, is often present in visible areas, and may occasionally be difficult to treat. Psoriasis can lead to depression and decreased quality of life. We performed a qualitative survey to examine patient perspectives on how psoriasis impacts their lives. Patients with psoriasis are vulnerable to embarrassment and stigmatization in public spaces, as well as discrimination at work, school, or in society. Further studies are needed to determine the best interventions for improving the quality of life...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Elizabeth Schoenberg Jordan V Wang Matthew Keller Source Type: research

Clinical Patterns and Clinicopathologic Correlation of 100 Patients with Erythroderma in a Tertiary Care Institute in India
Skinmed. 2021 Dec 1;19(6):440-450. eCollection 2021.ABSTRACTErythroderma is a severe dermatologic manifestation of a variety of diseases. We analyzed the clinical parameters and the clinicopathologic correlation in patients with erythroderma. Consecutive patients diagnosed with erythroderma at a tertiary care institute were evaluated for 5 years. Detailed history and clinical examination were noted along with extensive hematologic and biochemical investigations, radiologic studies, and skin biopsy for histopathologic examination, and if required, for immunoflourescence and immunohistochemistry; 83 men and 17 women were inc...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Rahul Mahajan Sunil Dogra Mousumi Roy Bandyopadhyay Uma Nahar Saikia Amrinder Jit Kanwar Source Type: research

Dermatofibrosarcoma Protuberans: A Dermatologic/dermatopathologic "Snake in the Grass"
Skinmed. 2021 Dec 1;19(6):452-455. eCollection 2021.NO ABSTRACTPMID:35022117 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Albert Alhatem Alyssa Swearingen Muriel W Lambert Rohan Shah Britney Wilson Robert A Schwartz W Clark Lambert Source Type: research

Dermatoscopic Patterns in Pellagra
Skinmed. 2021 Dec 1;19(6):456-457. eCollection 2021.NO ABSTRACTPMID:35022118 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Houda Hammami Samy Fenniche Source Type: research

Comedonal Lupus: An Unusual Presentation of Chronic Cutaneous Lupus Erythematosus
Skinmed. 2021 Dec 1;19(6):458-459. eCollection 2021.NO ABSTRACTPMID:35022119 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Fatma Hammami Emna Bahloul Abderrahmen Masmoudi Sonia Boudaya Meriem Amouri Hamida Turki Source Type: research

Cutaneous Desmoplastic Leiomyosarcoma Development at Smallpox Vaccination Site
Skinmed. 2021 Dec 1;19(6):462-463. eCollection 2021.ABSTRACTAn 81-year-old man presented to the clinic with a 2.1 cm firm, skin-colored subcutaneous tumor on the left upper arm (Figure 1). The lesion arose at the site of a past smallpox vaccination and had been slowly enlarging for approximately 4 years. The differential diagnosis included sympastic leiomyoma, and a variety of desmoplastic spindle cell lesions such as desmoplastic melanoma, cutaneous spindle cell carcinoma, and desmoplastic leiomyosarcoma. Punch biopsy and immunohistochemical staining revealed positive spindle cells for desmin and caldesmon (Figures 2 and ...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Meera H Patel Caitlin M Brumfiel David Glembocki Adam J Luber Source Type: research

Anetoderma in a Patient with Newly Diagnosed Hodgkin's Lymphoma
Skinmed. 2021 Dec 1;19(6):464-465. eCollection 2021.ABSTRACTA previously healthy 28-year-old woman was admitted to the hospital with respiratory failure and was found to have significant lymphadenopathy on her CT scan. A lymph node biopsy was performed; the pathology was consistent with a diagnosis of Hodgkin's lymphoma and the patient was noted to have multiple, wrinkled, nonscaly, oval-shaped papules that were easily compressible (Figure 1) and were present on the upper and lower extremities, abdomen, chest, and back. The lesions were entirely asymptomatic and had first developed 1 year prior to presentation. Since their...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Soniya Pateriya Nitin Tiwari Jeanne Young Source Type: research

Diffuse Large B-Cell Lymphoma in the Setting of Chronic Lymphocytic Leukemia
Skinmed. 2021 Dec 1;19(6):466-470. eCollection 2021.ABSTRACTA 77-year-old man was referred to our department with a 6-month history of a painless, rapidly enlarging tumor on the left leg. Fourteen years ago, he was diagnosed with chronic lymphocytic leukemia (CLL), and he had presented with lymphocytosis and multiple lymphadenopathies (Rai stage II). Both bone marrow aspiration and peripheral blood immunophenotyping identified a monoclonal B-cell population expressing surface CD5, CD20, CD23, CD43, and IgG kappa. At that time, he underwent eight courses of treatment with oral fludarabine, followed by complete remission, an...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Mariana Esteves Teresa Baudrier Ana Carneiro Filomena Azevedo Alberto Mota Source Type: research

Dupilumab for the Treatment of Actinic Prurigo
Skinmed. 2021 Dec 1;19(6):471-472. eCollection 2021.ABSTRACTA 42-year-old Latino man with a medical history of vitiligo presented to our outpatient clinic with a 25-year history of a recurrent, itchy eruption on his face and hands. Physical examination revealed pink, scaly, erythematous, lichenified papules and plaques with overlying crusts, photodistributed on the nose, chin, cheeks, hands, and ears (Figures 1a and 2a). The lips were edematous with hemorrhagic crusting, and conjunctival injection and partial corneal opacities were noted (Figures 1b-1c). Histologic evaluation demonstrated psoriasiform hyperplasia with hype...
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Allison M Perz Bilal Fawaz Tia Pyle Niraj Butala Justin J Green Source Type: research

Efficacy of Ablative Fractional CO2 Laser in the Treatment of a Cutaneous Leishmaniasis Scar
Skinmed. 2021 Dec 1;19(6):475-480. eCollection 2021.NO ABSTRACTPMID:35022124 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Anissa Zaouak Amal Chamli Houda Hammami Samy Fenniche Source Type: research

Cochlear Implant-Induced Contact Dermatitis
Skinmed. 2021 Dec 1;19(6):477-480. eCollection 2021.NO ABSTRACTPMID:35022125 (Source: Skinmed)
Source: Skinmed - January 13, 2022 Category: Dermatology Authors: Antonella Tammaro Ganiyat Adenike Ralitsa Adebanjo Francesca Romana Parisella Camilla Chello Francesca Magri Alvise Sernicola Edoardo Covelli Simonetta Monini Maurizio Barbara Source Type: research