Coverage, Trends, and Inequalities of Maternal, Newborn, and Child Health Indicators among the Poor and Non-Poor in the Most Populous Cities from 38 Sub-Saharan African Countries
AbstractRapid urbanization is likely to be associated with suboptimal access to essential health services. This is especially true in cities from sub-Saharan Africa (SSA), where urbanization is outpacing improvements in infrastructure. We assessed the current situation in regard to several markers of maternal, newborn, and child health, including indicators of coverage of health interventions (demand for family planning satisfied with modern methods, at least four antenatal care visits (ANC4+), institutional birth, and three doses of DPT vaccine[diphtheria, pertussis and tetanus]) and health status (stunting in children un...
Source: Journal of Urban Health - December 18, 2023 Category: Health Management Source Type: research

Trends of measles in Tanzania: a five-year review of case-based surveillance data, 2018-2022
Vaccines provide a safe and cost-effective solution to vaccine-preventable infectious diseases. However, vaccine-preventable infectious diseases still pose a serious public health threat especially in the world's poor regions[1]. In sub-Saharan Africa, this burden is further aggravated by the occurrence of concurrent epidemics such as Coronavirus Disease 2019 (COVID-19), Ebola virus disease, monkeypox, and measles overstretching the already weak public health system[2]. In addition to human conflicts, natural disasters, vaccine hesitancy, and the COVID-19 pandemic has disrupted routine immunisation services leaving million...
Source: International Journal of Infectious Diseases - December 17, 2023 Category: Infectious Diseases Authors: Fausta Michael, Mariam M. Mirambo, Gerald Misinzo, Omary Minzi, Medard Beyanga, Delphinus Mujuni, Florence S Kalabamu, Elias N Nyanda, Mary Mwanyika-Sando, Daniel Ndiyo, Richard Kasonogo, Abbas Ismail, Andrew Bahati, Farida Hassan, Elangiringa Kaale, John Source Type: research

Trends of measles in Tanzania: A 5-year review of case-based surveillance data, 2018-2022
Vaccines provide a safe and cost-effective solution to vaccine-preventable infectious diseases. However, vaccine-preventable infectious diseases still pose a serious public health threat, especially in the world's poor regions [1]. In sub-Saharan Africa, this burden is further aggravated by the occurrence of concurrent epidemics such as COVID-19, Ebola virus disease, monkeypox, and measles overstretching the already weak public health system [2]. In addition to human conflicts, natural disasters, and vaccine hesitancy, the COVID-19 pandemic has disrupted routine immunization services leaving millions of children under-vacc...
Source: International Journal of Infectious Diseases - December 17, 2023 Category: Infectious Diseases Authors: Fausta Michael, Mariam M. Mirambo, Gerald Misinzo, Omary Minzi, Medard Beyanga, Delphinus Mujuni, Florence S. Kalabamu, Elias N. Nyanda, Mary Mwanyika-Sando, Daniel Ndiyo, Richard Kasonogo, Abbas Ismail, Andrew Bahati, Farida Hassan, Eliangiringa Kaale, J Source Type: research

Successful management of severe generalized tetanus in a 23 ‐year man with phenobarbital adjuvant: A case report
We reported a 23-year-old man from Afghanistan admitted to emergency department, with the chief complaint of generalized severe spasms and lockjaw. The patient had skin lesions and had never been vaccinated against tetanus. He intubated and admitted to the intensive care unit (ICU) with diagnose of severe generalized tetanus. After receiving tetanus immunoglobulin and intravenous metronidazole, a combination therapy of midazolam, propofol, atracurium, and morphine was administered. Due to the refractory muscular spasms intravenous phenobarbital started and little by little recovery was achieved. The patient receiving the f...
Source: Clinical Case Reports - December 16, 2023 Category: General Medicine Authors: Arezoo Ahmadi, Elahe Karimpour ‐Razkenari, Ramin Ansari, Mahforouzalsadat Marashi, Hamidreza Sharifnia, Atabak Najafi, Mojtaba Mojtahedzadeh Tags: CASE REPORT Source Type: research

Effective and safe transfer of maternal antibodies persisting two months postpartum following maternal immunization with different doses of recombinant pertussis-containing vaccines
CONCLUSIONS: BioNet licensed (TdaP5gen and Tdap2gen) and candidate vaccines (Tdap1gen and ap1gen) when given to pregnant women in the second or third trimester of gestation are safe and have induced passive pertussis immunity to infants.PMID:38061956 | DOI:10.1016/j.vaccine.2023.11.042 (Source: Vaccine)
Source: Vaccine - December 7, 2023 Category: Allergy & Immunology Authors: Kulkanya Chokephaibulkit Thanyawee Puthanakit Surasith Chaithongwongwatthana Niranjan Bhat Yuxiao Tang Suvaporn Anugulruengkitt Chenchit Chayachinda Sanitra Anuwutnavin Keswadee Lapphra Supattra Rungmaitree Monta Tawan Indah Andi-Lolo Renee Holt Librada F Source Type: research

Effective and safe transfer of maternal antibodies persisting two months postpartum following maternal immunization with different doses of recombinant pertussis-containing vaccines
CONCLUSIONS: BioNet licensed (TdaP5gen and Tdap2gen) and candidate vaccines (Tdap1gen and ap1gen) when given to pregnant women in the second or third trimester of gestation are safe and have induced passive pertussis immunity to infants.PMID:38061956 | DOI:10.1016/j.vaccine.2023.11.042 (Source: Vaccine)
Source: Vaccine - December 7, 2023 Category: Allergy & Immunology Authors: Kulkanya Chokephaibulkit Thanyawee Puthanakit Surasith Chaithongwongwatthana Niranjan Bhat Yuxiao Tang Suvaporn Anugulruengkitt Chenchit Chayachinda Sanitra Anuwutnavin Keswadee Lapphra Supattra Rungmaitree Monta Tawan Indah Andi-Lolo Renee Holt Librada F Source Type: research

Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child cohort
Environ Res. 2023 Nov 30:117814. doi: 10.1016/j.envres.2023.117814. Online ahead of print.ABSTRACTExposure to per- and polyfluoroalkyl substances (PFAS) has been associated with reduced antibody response to childhood vaccinations. Previous studies have mostly focused on antibodies against diphtheria or tetanus, while fewer studies have assessed antibodies toward attenuated viruses, such as measles, mumps or rubella (MMR). Therefore, we set out to determine associations between prenatal and early postnatal PFAS exposure and vaccine-specific Immunoglobulin G (IgG) in the background-exposed Odense Child Cohort. Blood samples ...
Source: Environmental Research - December 2, 2023 Category: Environmental Health Authors: Annika Sigvaldsen Frederik Damsgaard H øjsager Helene Martina Paarup Iben Have Beck Amalie Timmermann Henriette Boye Flemming Nielsen Thorhallur I Halldorsson Christel Nielsen S ören Möller Torben Barington Philippe Grandjean Tina Kold Jensen Source Type: research

Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child cohort
Environ Res. 2023 Nov 30:117814. doi: 10.1016/j.envres.2023.117814. Online ahead of print.ABSTRACTExposure to per- and polyfluoroalkyl substances (PFAS) has been associated with reduced antibody response to childhood vaccinations. Previous studies have mostly focused on antibodies against diphtheria or tetanus, while fewer studies have assessed antibodies toward attenuated viruses, such as measles, mumps or rubella (MMR). Therefore, we set out to determine associations between prenatal and early postnatal PFAS exposure and vaccine-specific Immunoglobulin G (IgG) in the background-exposed Odense Child Cohort. Blood samples ...
Source: Environmental Research - December 2, 2023 Category: Environmental Health Authors: Annika Sigvaldsen Frederik Damsgaard H øjsager Helene Martina Paarup Iben Have Beck Amalie Timmermann Henriette Boye Flemming Nielsen Thorhallur I Halldorsson Christel Nielsen S ören Möller Torben Barington Philippe Grandjean Tina Kold Jensen Source Type: research

Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data
To the Editor We read with great interest a recent study by Dorney et al, concluding that there was no association between messenger RNA (mRNA) COVID-19 vaccination and newly diagnosed retinal vascular occlusion (RVO) with similar rates compared with those following influenza and tetanus, diphtheria, and pertussis (Tdap) vaccines. However, we have several methodological concerns and suggestions. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research

Recurrent diphtheria outbreaks in Nigeria: A review of the underlying factors and remedies
ConclusionThe underlying causes of Nigeria's low DTP coverage and DAT supply are multifactorial. Both short-term and long-term measures are needed to control this outbreak and prevent future occurrences. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 29, 2023 Category: Allergy & Immunology Authors: Nasir Abdulrasheed, Lukman Lawal, Abdulazeez B. Mogaji, Ahmed O. Abdulkareem, Abdulrahman K. Shuaib, Sodiq G. Adeoti, Opeyemi P. Amosu, Abdulmujeeb O. Muhammad ‐Olodo, Abdulwahab O. Lawal, Tawakalitu A. Jaji, Toufik Abdul‐Rahman Tags: REVIEW ARTICLE Source Type: research

Missed opportunities: Reducing zero dose children amongthe urban poor after COVID, Mumbai India, 2022
Vaccine. 2023 Nov 27:S0264-410X(23)01339-7. doi: 10.1016/j.vaccine.2023.11.027. Online ahead of print.ABSTRACTReaching urban poor populations poses challenges for equitable immunization coverage. Furthermore, COVID disrupted routine immunization services. In Mumbai, India, first dose diphtheria tetanus pertussis containing vaccine (DTPCV1)coverage dropped from 88% (2019) to 76% (2021). We identified and characterized 125 zero-dose (those withoutDTPCV1)migrant children in urban Mumbai in October 2022. Almost half were born elsewhere than Mumbai; 53% resided at their present location for less than a year. More than half were...
Source: Vaccine - November 28, 2023 Category: Allergy & Immunology Authors: Meeta Dhaval Vashi Margaret Watkins Source Type: research

Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study
CONCLUSION: Vaccination coverage of PedRD patients has been shown to lag behind the routine vaccination schedule (71.4%). In addition to new recommendations, electronic health system records for vaccination may be appropriate for the follow-up of these patients, and the addition of reminder alerts may be useful to reduce the rate of missed vaccinations.PMID:37997766 | DOI:10.1080/00325481.2023.2287988 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Özlem Akgün Fatma G ül Demirkan G ülşah Kavrul Kayaalp Merve Erdemir Nergis Akay Figen Çakmak Mustafa Önel Gonca Keskindemirci Rukiye Eker Ömeroğlu Emine G ülbin Gökçay Nuray Aktay Ayaz Source Type: research