Nanolayered drug-release systems for regenerative medicine and targeted nanotherapies
NIH Director's Wednesday Afternoon Lecture Series Margaret Pittman Lecture Alternating electrostatic assembly is a tool that makes it possible to create ultrathin film coatings that contain highly controlled quantities of one or more therapeutic molecules within a singular construct. These release systems greatly exceed the usual ranges of traditional degradable polymers. The nature of the layering process enables the incorporation of different drugs within different regions of the thin-film architecture; the result is an ability to uniquely tailor both the independent-release profiles and order-of-release of each therap...
Source: Videocast - All Events - May 25, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

CRISPR-Cas genome surveillance: From basic biology to transformative technology
Wednesday Afternoon Lecture Series Margaret Pittman Lecture Dr. Doudna, who specializes in the study of RNA, will present a brief history of the bacterial RNA-guided CRISPR biology from its initial discovery through the elucidation of the CRISPR-Cas9 enzyme mechanism. Using CRISPR-Cas (clustered regularly interspaced short palindromic repeats) technology provides the foundation for remarkable developments in modifying, regulating, or marking genomic loci in a wide variety of cells and organisms. These results highlight a new era in which genomic manipulation is no longer a bottleneck to experiments, paving the way to fun...
Source: Videocast - All Events - March 9, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video