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Specialty: Pediatrics
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Total 35 results found since Jan 2013.

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What are Some Risk Factors for Hypoxic-Ischemic Encephalopathy Outcomes?
Discussion “Neonatal encephalopathy, manifesting as altered responsiveness, seizures, apnea and abnormal muscle tone and reflexes, resulting from hypoxic-ischemic injury is termed hypoxic-ischemic encephalopathy (HIE).” Neonatal encephalopathy can be associated with other problems including stroke, hemorrhage, infection, pre-term brain injury and hypoglycemia as some examples. Sometimes more than one of these entities occurs simultaneously such as hypoglycemia and HIE. HIE can result in long-term neurological problems including motor, behavioral, and cognitive problems that can become apparent even years later....
Source: PediatricEducation.org - December 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Efficacy of Citicoline as a Neuroprotector in children with post cardiac arrest: a randomized controlled clinical trial
Conclusion: Citicoline is a promising neuroprotective drug in children with post-cardiac arrest.Trial Registration: The study was registered at Pan African Clinical Trials Registry (PACTR)www.pactr.samrc.ac.za with trial number PACTR201907742119058.What is known?• Post-resuscitation brain injury is one of the major complications that can lead to death or disability.• CDP-choline has been studied for acute ischemic stroke in several adult studies because of its reparative effect.What is new?• Our study was the first in pediatrics that assessed the neuroprotective effect of CDP-choline on the brain in children after ca...
Source: European Journal of Pediatrics - November 10, 2020 Category: Pediatrics Source Type: research

Behavioral characteristics of children with sickle cell disease
Conclusions: Behavioral impacts are highly prevalent in children with SCD. Individuals in socioeconomic classes C2 and D suffered more behavioral impacts than individuals in classes B2 and C1.RESUMO Objetivo: Avaliar aspectos sociodemogr áficos e clínicos de crianças com doença falciforme (DF) e suas características comportamentais. Métodos: Aplicação de entrevista sobre aspectos socioeconômicos e outras condições de saúde e do questionário de capacidades e dificuldades (SDQ) em pais de pacientes de quatro a dez anos com DF, em um ambulatório de referência. Dados clínicos foram obtidos dos prontuários méd...
Source: Revista Paulista de Pediatria - August 13, 2020 Category: Pediatrics Source Type: research

What Types of Memory Impairments are There in Children?
Discussion Memory is an important part of what distinguishes higher order species from others. Memory also is part of one’s self-identity. Difficulties in short-term memory can make common, everyday tasks difficult for the person experiencing the problem particularly if it recently occurred and the person’s long-term memory is intact. Difficulties with long-term memory can also have problems when language, events or even one’s own identity are affected. For some people the memory loss is temporary but for others, memory impairments are permanent and must be accepted and accommodated as part of the overall...
Source: PediatricEducation.org - March 30, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Validation of the pediatric stroke outcome measure for classifying overall neurological deficit.
CONCLUSION: The PSOM-SCS constitutes a valid tool for classifying overall neurological severity emphasizing function and encompassing the full range of severity in pediatric stroke. IMPACT: Arithmetic summing of the PSOM subscales scores to assess severity classification is inadequate.The prior severity classification using PSOM overestimates poor outcomes.Three distinct severity profiles using PSOM subscales are identified.The PSOM-SCS is in moderate to excellent agreement with other disability measures.PSOM-SCS offers a valid tool for classifying the overall neurological deficit severity. PMID: 32179868 [PubMed...
Source: Pediatric Research - March 15, 2020 Category: Pediatrics Authors: Slim M, Fox CK, Friefeld S, Dlamini N, Westmacott R, Moharir M, MacGregor D, deVeber G, SIPS Investigators Tags: Pediatr Res Source Type: research

What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Understanding the Global Prevalence of Hypertension in Children and Adolescents
Hypertension is a major risk factor for the development of cardiovascular disease morbidity and mortality worldwide. Stroke, heart failure, myocardial infarction, and peripheral arterial disease are all outcomes associated with hypertension in adults. Hypertension is also considered to be a major cause of poorer disability-adjusted life-years. The prevalence of hypertension in adults has been debated in part because the definition of hypertension has changed over time. The association between blood pressure and cardiovascular disease is a continuous one, making the establishment of a cut point for hypertension difficult. H...
Source: JAMA Pediatrics - October 7, 2019 Category: Pediatrics Source Type: research

Nonpharmacological rehabilitation interventions for motor and cognitive outcomes following pediatric stroke: a systematic review
Conclusion: Effective rehabilitation approaches are important for optimizing outcomes in children who have had a stroke. Although the number of published clinical trials has increased in recent years, little evidence-based guidance exists for this clinical population.What is Known:• Pediatric stroke is a significant cause of disability in children that is often associated with long-term motor and cognitive sequelae.• There is a need to establish a knowledge base regarding available evidence-based rehabilitation therapies for this clinical population.What is New:• Most studies examining interventions for motor functio...
Source: European Journal of Pediatrics - February 27, 2019 Category: Pediatrics Source Type: research

Teamwork and toughness: Living with cerebral palsy
Growing up in Querétaro, Mexico, María was an exceptionally bright and inquisitive child. At just 18 months old, she spoke at the level of a 6-year-old, and could even sing the tongue-twisting “Supercalifragilisticexpialidocious” song. Her parents marveled at her intelligence at such a young age, but there was something in her development that seemed off. “At 1 year, she wasn’t crawling well and had difficulty standing,” her mother, María José, recalls. “She hadn’t learned to walk by 18 months, and she would crawl by pulling her two legs at the same time — like a little bunny.” Her parents knew that s...
Source: Thrive, Children's Hospital Boston - February 2, 2018 Category: Pediatrics Authors: Connor Ertz Tags: Our Patients’ Stories cerebral palsy Cerebral Palsy Center Child and Young Adult Hip Preservation Program Dr. Benjamin Shore Dr. Donna Nimec Source Type: news

Cerebral vasculopathy in children with sickle cell disease: Key issues and the latest data.
Abstract Cerebral vasculopathy is a common and severe complication of sickle cell disease in children. The pathophysiology consists of progressive damage to the basal intracranial arteries and cerebral microcirculation, while chronic anemia worsens exposure to cerebral hypoxia. It results in stroke and subclinical or poorly symptomatic ischemic lesions. Many clinical, biological, and radiological risk factors have been identified. The prevention strategy through systematic transcranial Doppler screening of large-vessel vasculopathy has revolutionized the management of this disease and has greatly decreased the ris...
Source: Archives de Pediatrie - December 15, 2017 Category: Pediatrics Authors: Corvest V, Blais S, Dahmani B, De Tersant M, Etienney AC, Maroni A, Ormières C, Roussel A, Pondarré C Tags: Arch Pediatr Source Type: research

Can Fish Oil Help Reading?
Discussion Fats and fatty acids are essential for good human health. Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet. Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature. Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Source: PediatricEducation.org - November 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Cellular therapy for traumatic neurological injury.
Abstract Neurological injury is the primary lethal mechanism of injury in children, and the primary etiology of long-term disability after trauma. Laboratories and clinical/translational teams have sought to develop stem/progenitor cell therapies to improve recovery in a clinical setting in which there is no significant reparative option. While none of these treatments are currently standard therapeutics, Phase 2b clinical trials are underway in both adults and children in severe traumatic brain injury and Phase 1/2a trials in spinal cord injury. This review will characterize the cell therapy strategies: cell repl...
Source: Pediatric Research - October 6, 2017 Category: Pediatrics Authors: Cox CS Tags: Pediatr Res Source Type: research

What Causes Microcephaly?
Discussion Microcephaly is usually defined as an occipitofrontal head circumference (OFC) more than 2 standard deviations (SD) below the mean for sex, age and ethnicity. Severe microcephaly is used for OFC < 3 standard deviations. Rates of microcephaly range from 0.5-12 patients/10,000 live births. The OFC should be measured at every well child visit and at other opportunities and plotted on standard growth charts. The OFC is measured using a nonelastic tape measure around the largest part of the head with the tape measure held above the eyebrows and ears. It is a highly reproducible measurement. There are several diff...
Source: PediatricEducation.org - September 25, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

A new life for Lynkin after encephalocele surgery
When you meet Lynkin Bell, the first things you notice are her big personality and chubby cheeks. You might also see how she adores her brother Lukis and hamming it up for the camera. But you’d never guess that this playful 14-month-old from Texas wasn’t expected to survive, never mind talk, stand or play peekaboo like a pro. And yet, thanks to her parents’ faith and persistence — and surgery at Boston Children’s Hospital — Lynkin can do all those things, and lots more, with the gusto befitting any toddler her age. “It’s a miracle,” says Kaylen Gaston, Lynkin’s mom. “We were told so many times she wou...
Source: Thrive, Children's Hospital Boston - April 24, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories Craniofacial Program Dr. John Meara Dr. Mark Proctor encephalocele Source Type: news