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Condition: Disability

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Total 13528 results found since Jan 2013.

Current practice of outpatient rehabilitation services in patients with mobility-impaired paralysis due to stroke or spinal cord injury: a qualitative interview study in Germany
CONCLUSION: Areas of improvement identified focused on: setting rehabilitation goals towards participation, training therapists on evidence-based treatments and shared decision-making, updating the outpatient service catalogue, and implementing coordination actions. Implementation of these recommendations should be evaluated.PMID:37732606 | DOI:10.1080/09638288.2023.2259301
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Tiziana Daniel Tamara Spingler Andreas Hug Norbert Weidner Michel Wensing Charlotte Ullrich Source Type: research

Knowledge and awareness of stroke and associated factors in the Saudi general population: a cross-sectional study
ConclusionOur study revealed that participants have good knowledge about stroke. Nonetheless, further efforts are required to raise awareness and educate the public to optimize and ensure better treatment outcomes.
Source: Frontiers in Neurology - September 21, 2023 Category: Neurology Source Type: research

Transport use limitations and its association with social participation among patients with stroke living in rural India
CONCLUSIONS: Independent use of different modes of transport, particularly public transportation, reduced among rural Indian stroke survivors. These transport limitations are significantly associated with reduced social participation, highlighting the need for interventions to improve accessibility and fostering greater community engagement for stroke survivors in this population.IMPLICATIONS FOR REHABILITATIONLimited transportation access limits social participation for stroke survivors in rural India.Study results show a significant decrease in independent transport use among stroke survivors, affecting their social part...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: Kajal Chavda V Prakash Source Type: research

Standardized circuit class group training versus individualized goal-directed group training to improve upper limb function in stroke survivors during in-patient rehabilitation: a pragmatic trial
CONCLUSIONS: A standardized training could reduce the mental workload for therapists, but patients seemed less engaged. A combination of both might be most beneficial.Trial registration: Dutch Trial Register: NL8844 and NL9471IMPLICATIONS FOR REHABILITATIONProviding a standardized training program after stroke reduces therapists' mental workload.Individualized goal-directed group training results in the best achievement of rehabilitation goals.A combination of standardized and individual training would use best of both intervention modalities.Patients should be involved in the co-creation developing process of training pro...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: S G Rozevink C M Beerepoot C K van der Sluis J M Hijmans Source Type: research

Protein kinase D2 confers neuroprotection by promoting AKT and CREB activation in ischemic stroke
In this study, we found that PKD2 expression and activity were significantly upregulated in the ipsilateral side of the brain after transient focal cerebral ischemia, which coincides with the upregulation of PKD2 in primary neurons in response to in vitro ischemia, implying a potential role of PKD2 in neuronal survival in ischemic stroke. Using kinase-dead PKD2 knock-in (PKD2-KI) mice, we examined whether loss of PKD2 activity affected stroke outcomes in mice subjected to 1 h of transient middle cerebral artery occlusion (tMCAO) and 24 h of reperfusion. Our data demonstrated that PKD2-KI mice exhibited larger infarction vo...
Source: Neurobiology of Disease - September 20, 2023 Category: Neurology Authors: Jaclyn A Connelly Xuejing Zhang Yuzhou Chen Yapeng Chao Yejie Shi Tija C Jacob Q Jane Wang Source Type: research

Transport use limitations and its association with social participation among patients with stroke living in rural India
CONCLUSIONS: Independent use of different modes of transport, particularly public transportation, reduced among rural Indian stroke survivors. These transport limitations are significantly associated with reduced social participation, highlighting the need for interventions to improve accessibility and fostering greater community engagement for stroke survivors in this population.IMPLICATIONS FOR REHABILITATIONLimited transportation access limits social participation for stroke survivors in rural India.Study results show a significant decrease in independent transport use among stroke survivors, affecting their social part...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: Kajal Chavda V Prakash Source Type: research

Standardized circuit class group training versus individualized goal-directed group training to improve upper limb function in stroke survivors during in-patient rehabilitation: a pragmatic trial
CONCLUSIONS: A standardized training could reduce the mental workload for therapists, but patients seemed less engaged. A combination of both might be most beneficial.Trial registration: Dutch Trial Register: NL8844 and NL9471IMPLICATIONS FOR REHABILITATIONProviding a standardized training program after stroke reduces therapists' mental workload.Individualized goal-directed group training results in the best achievement of rehabilitation goals.A combination of standardized and individual training would use best of both intervention modalities.Patients should be involved in the co-creation developing process of training pro...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: S G Rozevink C M Beerepoot C K van der Sluis J M Hijmans Source Type: research

Renal Dysfunction Among Stroke Patients, Hospital Based Cross Sectional Study, Addis Ababa, Ethiopia, 2021
Conclusion: Renal  dysfunction is a frequent comorbidity in patients who are admitted with the diagnosis of acute stroke and had a higher mortality rate  than stroke patients with normal renal function. 
Source: Ethiopian Journal of Health Development - September 20, 2023 Category: African Health Authors: Lissane Seifu, Yonas Gashaye, Melaku Taye Source Type: research

Persian version of the Chalder Fatigue Questionnaire and Multidimensional Fatigue Symptom Inventory-Short Form: psychometric properties in Iranian chronic stroke survivors
CONCLUSIONS: The results of this study showed that the CFQ and MFSI-SF have high reliability and validity for chronic stroke survivors.PMID:37723098 | DOI:10.1080/10749357.2023.2175421
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Soheila Fallah Ghorban Taghizadeh Zahra Parnain Moslem Cheraghifard Parvaneh Taghavi Azar Sharabiani Mahin Yousefi Mohammad Taghi Joghataei Ali Gholizade Source Type: research

Challenges of neural interfaces for stroke motor rehabilitation
More than 85% of stroke survivors suffer from different degrees of disability for the rest of their lives. They will require support that can vary from occasional to full time assistance. These conditions are also associated to an enormous economic impact for their families and health care systems. Current rehabilitation treatments have limited efficacy and their long-term effect is controversial. Here we review different challenges related to the design and development of neural interfaces for rehabilitative purposes. We analyze current bibliographic evidence of the effect of neuro-feedback in functional motor rehabilitat...
Source: Frontiers in Human Neuroscience - September 18, 2023 Category: Neuroscience Source Type: research

Sensors, Vol. 23, Pages 7946: Explainable Risk Prediction of Post-Stroke Adverse Mental Outcomes Using Machine Learning Techniques in a Population of 1780 Patients
In this study, we aimed to develop a machine learning (ML) model to predict the risk of PSAMO. We retrospectively studied 1780 patients with stroke who were divided into PSAMO vs. no PSAMO groups based on results of validated depression and anxiety questionnaires. The features collected included demographic and sociological data, quality of life scores, stroke-related information, medical and medication history, and comorbidities. Recursive feature elimination was used to select features to input in parallel to eight ML algorithms to train and test the model. Bayesian optimization was used for hyperparameter tuning. Shaple...
Source: Sensors - September 17, 2023 Category: Biotechnology Authors: Chien Wei Oei Eddie Yin Kwee Ng Matthew Hok Shan Ng Ru-San Tan Yam Meng Chan Lai Gwen Chan Udyavara Rajendra Acharya Tags: Communication Source Type: research

Management of Acute Cerebral Infarction by Intravenous Thrombolysis with Recombinant T Cell Receptor and Plasminogen Activator and Association of Emergency Nursing Route in the Prognosis
In this study, 100 patients were randomly selected that were equally divided into experimental and control groups. The period of hospital admission, the results of the Montreal Cognitive Assessment (MoCA) and the Mini-mental State Examination (MMSE), the results of the Glasgow Outcome Scale (GOS), and the results of the Activities of Daily Living were all analysed before and after the intervention.. Both the amount of time it took to get a diagnosis after being admitted and the amount of time it took to receive specialised therapy after receiving a diagnosis were significantly reduced in the observation group (both P value...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: None Yuqi Liu None Chengyong Wang None Yuanpeng Han Source Type: research

The cell-specific roles of Nrf2 in acute and chronic phases of ischemic stroke
CNS Neurosci Ther. 2023 Sep 16. doi: 10.1111/cns.14462. Online ahead of print.ABSTRACTIschemic stroke refers to the sudden loss of blood flow in a specific area of the brain. It is the fifth leading cause of mortality and the leading cause of permanent disability. The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) controls the production of several antioxidants and protective proteins and it has been investigated as a possible pharmaceutical target for reducing harmful oxidative events in brain ischemia. Each cell type exhibits different roles and behaviors in different phases post-stroke, which is...
Source: CNS Neuroscience and Therapeutics - September 16, 2023 Category: Neuroscience Authors: George Fadoul Milos Ikonomovic Feng Zhang Tuo Yang Source Type: research