Efficacy of Citicoline as a Neuroprotector in children with post cardiac arrest: a randomized controlled clinical trial

Conclusion: Citicoline is a promising neuroprotective drug in children with post-cardiac arrest.Trial Registration: The study was registered at Pan African Clinical Trials Registry (PACTR)www.pactr.samrc.ac.za with trial number PACTR201907742119058.What is known?• Post-resuscitation brain injury is one of the major complications that can lead to death or disability.• CDP-choline has been studied for acute ischemic stroke in several adult studies because of its reparative effect.What is new?• Our study was the first in pediatrics that assessed the neuroprotective effect of CDP-choline on the brain in children after cardiac arrest.• We found that Citicoline is a promising neuroprotective drug in children with post-cardiac arrest.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research