• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Abnormal neurodevelopmental outcomes are very likely in cases of bilateral neonatal arterial ischaemic stroke
ConclusionOur study showed that abnormal neurodevelopmental outcomes were very likely after cases of neonatal AIS with bilateral involvement and clinicians should consider early and more effective interventions in such cases.This article is protected by copyright. All rights reserved.
Source: Acta Paediatrica - October 31, 2016 Category: Pediatrics Authors: Ju Hyun Jin, Jeong Eun Shin, Soonmin Lee, Ho Sun Eun, Min Soo Park, Kook In Park, Ran Namgung Tags: Regular Article Source Type: research

Using animal models to improve care of neonatal encephalopathy
Introduction Neonatal encephalopathy (NE) is responsible for a significant burden of disability and death worldwide.1 The use of animal models in the study of perinatal hypoxia-ischaemia (HI) has a history of over 200 years; studies initially showed that the premature animal is more tolerant of asphyxia than a term animal, which is in turn more resistant to asphyxia than an adult.2 3 In the 1950s to the 1970s, studies in the primate model showed that the pattern of brain injury was clearly influenced by the severity and type of HI; these studies led to a description of two patterns of injury, namely acute total asphyx...
Source: Archives of Disease in Childhood - Education and Practice - September 19, 2016 Category: Pediatrics Authors: Lingam, I., Avdic-Belltheus, A., Robertson, N. J. Tags: Clinical trials (epidemiology), Neurological injury, Stroke, Child health, Neonatal and paediatric intensive care, Neonatal health, Experiments in vivo, Trauma, Injury Research in practice Source Type: research

Paraplegics Regain Some Feeling, Movement After Using Brain-Machine Interfaces
This study was funded by grants from the Brazilian Financing Agency for Studies and Projects (FINEP 01 ·12·0514·00), Brazilian Ministry of Science, Technology and Innovation, and the Itaú Bank. The authors list additional acknowledgements in the manuscript. They declared no competing financial interests related to this work.###
Source: DukeHealth.org: Duke Health Features - August 11, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Answers to Epilogue questions
AnswersQuestion 1: C Unenhanced CT examination of the brain revealed extensive thrombosis in the superior sagittal, straight and left transverse sinuses (figure 1). The CT angiogram (figure 2) confirmed venous thrombosis and an arterial infarct. It revealed complete occlusion of left internal carotid artery and segmental vasculopathy, affecting multiple intracranial and extracranial vessels of both the anterior and posterior circulation along with an aneurysmal ascending aorta. The contrast-enhanced CT scan demonstrated a filling defect of the superior sagittal sinus with minimal peripheral contrast enhancement, known as t...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Mundada, V., Krishnakumar, D., Chitre, M., Das, T. Tags: Journalology, Eye Diseases, Stroke, Diet, Ophthalmology, Child and adolescent psychiatry (paedatrics), Radiology, Disability, Rheumatology, Dermatology, Clinical diagnostic tests, Radiology (diagnostics), Competing interests (ethics), Metabolic disorders Source Type: research

Moyamoya and childhood stroke: Catching up with Tyler and Ryan
Ryan (above left) and Tyler Earle of Winnipeg, Canada had a ticking time bomb inside their heads. Both boys have a rare brain disorder called moyamoya that had caused the arteries feeding their brains to become dangerously narrowed. At first, they experienced only headaches. But then Ryan suddenly lost his ability to write, began having trouble with word-finding and became weak on one side of his body — signs he had suffered a stroke. He was diagnosed with moyamoya and had partial surgery, but a second stroke took away part of his vision and partially paralyzed him. Ryan needed a second operation as soon as possible. By ...
Source: Thrive, Children's Hospital Boston - May 12, 2016 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Cerebrovascular Disorders and Stroke Program Dr. Edward Smith moyamoya Source Type: news

What Genetics are Associated with Multiple Sclerosis?
Discussion Multiple sclerosis (MS) is “a chronic degenerative, often episodic disease of the central nervous system marked by patchy destruction of the myelin that surrounds and insulates nerve fibers, usually appearing in young adulthood and manifested by one or more mild to severe neural and muscular impairments, as spastic weakness in one or more limbs, local sensory losses, bladder dysfunction, or visual disturbances.” It is a chronic disease and therefore symptoms must occur more than once. The first episode is called an acute demyelinating attack. Fifteen to forty-five percent of children with their first...
Source: PediatricEducation.org - April 4, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Experience Journal: Growing up with cerebral palsy
Cerebral palsy (CP) is the most common physical disability of childhood. The term CP is an umbrella term for a group of disorders that affect body movement and posture as a result of damage to a baby’s developing brain. There are many causes for CP, but all occur either during pregnancy, birth or shortly after birth. Common causes include differences in brain development, infection or stroke. Oxygen deprivation is accountable for only a small percentage of cases of CP; often, the cause is unknown. Although CP is a lifelong condition that can’t be reversed, children with the diagnosis can lead rich, fulfilling lives wit...
Source: Thrive, Children's Hospital Boston - March 18, 2016 Category: Pediatrics Authors: Erin Horan Tags: Experience Journal Cerebral Palsy Program Source Type: news

Chronic Neuromotor Disability After Complex Cardiac Surgery in Early Life
This study focuses on the presence of chronic neuromotor disabilities including cerebral palsy and motor impairments after acquired brain injury in children surviving early complex cardiac surgery, providing information on the frequency, characteristics, and predictors that may assist in prevention. (Read the full article)
Source: PEDIATRICS - October 1, 2015 Category: Pediatrics Tags: Pediatrics Digest Summary Source Type: research

Repeated Autologous Umbilical Cord Blood Infusions are Feasible and had No Acute Safety Issues in Young Babies with Congenital Hydrocephalus.
CONCLUSION: Cryopreserved CB products may be effectively manipulated to provide multiple CB doses. Repeated intravenous infusion of autologous CB is safe and feasible in young babies with congenital hydrocephalus.Pediatric Research (2015); doi:10.1038/pr.2015.161. PMID: 26331765 [PubMed - as supplied by publisher]
Source: Pediatric Research - September 2, 2015 Category: Pediatrics Authors: Sun JM, Grant GA, McLaughlin C, Allison J, Fitzgerald A, Waters-Pick B, Kurtzberg J Tags: Pediatr Res Source Type: research

Advancing Neurologic Care in the Intensive Care Nursery
Up to 25% of neonates at tertiary care nurseries are diagnosed as having neurologic conditions, including encephalopathy and hypoxic-ischemic encephalopathy [HIE], as well as seizures, stroke, and intracranial hemorrhage. These children are at high risk for lifelong disabilities, including cerebral palsy, epilepsy, and cognitive and behavioral disabilities. Establishing a neurointensive care nursery involves a culture change toward brain-focused care, with all bedside clinicians (including physicians, nurses, respiratory technologists, and trainees) maintaining constant awareness of the potential neurologic complications o...
Source: NeoReviews recent issues - September 1, 2015 Category: Pediatrics Authors: Glass, H. C. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Idaho mom goes the distance to help teen with scoliosis
“You want a hospital with the best technology and the best nurses and doctors in the country. You expect that, and you expect it to be clean. Boston Children’s has all of that,” says Lisa Findlay, a mom from Hayden, Idaho. “What made the difference was how much everyone loves these kids. Everyone who walked into Aaron’s room, from the surgeons to nurses’ aides to janitors and child life specialists, was on a mission to help Aaron.” From the time he was born, Aaron encountered one medical challenge after another. He was born with hypoplastic left heart syndrome (HLHS), a serious congenital heart defect. By...
Source: Thrive, Children's Hospital Boston - April 2, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Orthopedics Our patients’ stories Source Type: news

Progesterone for Neuroprotection in Pediatric Traumatic Brain Injury
Conclusions: The unique features of the developing brain from that of a mature adult brain make it necessary to independently study progesterone in clinically relevant, immature animal models of traumatic brain injury. Additional preclinical studies could lead to the development of a novel neuroprotective therapy that could reduce the long-term disability in head-injured children and could potentially provide benefit in other forms of pediatric brain injury (global ischemia, stroke, and statue epilepticus).
Source: Pediatric Critical Care Medicine - March 1, 2015 Category: Pediatrics Tags: Neurocritical Care Source Type: research

Screening of cerebral vasculopathy in sickle cell anemia children using transcranial Doppler.
Abstract Cerebral vasculopathy exposes patients to a high risk of stroke, a major complication of sickle cell disease (SCD) associated with a high risk of death and disability. Transcranial doppler (TCD) ultrasonography used to identify SCD patients at risk of stroke may contribute to significantly reducing morbidity and mortality in these patients by indicating appropriate treatment. From March 2008 to February 2013, we conducted systematic screening for cerebral vasculopathy using TCD in 572 SCD patients (including 375 SS, 144 SC, 26 S/β(0), and 27 S/β(+) thalassemia patients) aged 1-17 years in a compre...
Source: Archives de Pediatrie - January 27, 2015 Category: Pediatrics Authors: Dorie A, Guindo A, Saro YS, Touré BA, Fané B, Dembelé AK, Diallo DA Tags: Arch Pediatr Source Type: research

Management and 2-year follow-up of children aged 29days to 17years hospitalized for a first stroke in France (2009-2010).
CONCLUSION: This is the first study to report the epidemiology of childhood stroke in France. The validity of this study is supported by the fact that it demonstrated homogeneous descriptive indicators to those obtained by means of various methodologies in other populations. The high mortality, recurrence, and disability rates observed during the year following the initial stroke encourage continuation of the ongoing process of standardizing the management of childhood stroke in France. PMID: 25287139 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - October 3, 2014 Category: Pediatrics Authors: Tuppin P, Samson S, Woimant F, Chabrier S Tags: Arch Pediatr Source Type: research

Pages: 1  2  3