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Total 733 results found since Jan 2013.

Epigenetics of Early-Life Socioeconomic Stressors and the Impact on Childhood Body Mass Index —Potential Mechanism and Biomarker?
Overweight and obesity are growing epidemics worldwide. Recent estimates from the World Health Organization indicate that 39% of adults had overweight, and 13% had obesity. In addition, an estimated 340 million children and adolescents aged 5 to 19 years had overweight or obesity in 2016 whereas 39 million children younger than 5 years had overweight or obesity in 2020. Understanding the biological mechanisms behind the development of overweight and obesity is critical as overweight and obesity are risk factors for a host of cardiometabolic outcomes including heart disease, stroke, diabetes, and chronic kidney disease. The...
Source: JAMA Pediatrics - September 5, 2023 Category: Pediatrics Source Type: research

What Are the Complications of Sickle Cell Trait?
Discussion Sickle cell disease (SCD) is a group of inherited blood disorders where there are abnormal hemoglobin molecules and the red blood cells take on a characteristic sickled shape instead of a rounded shape. Sickled hemoglobin provides an evolutionary advantage of giving the individual increased protection against severe and cerebral malaria. The sickled shape doesn’t move through the vascular system as well and therefore is more likely to aggregate in small vessels causing an increased risk of vaso-occlusive disease, acute chest syndrome, splenic sequestration, and priapism. There is also an increased risk of ...
Source: PediatricEducation.org - September 4, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Vertigo and dizziness in children: When to consider a neurological cause
Arch Pediatr. 2023 Aug 1:S0929-693X(23)00132-X. doi: 10.1016/j.arcped.2023.07.001. Online ahead of print.ABSTRACTVertigo is common in childhood and adolescence. Although children and adults share common causes of vertigo, epidemiology changes with aging. For instance, ischemic stroke is less frequent in childhood, whereas audiovestibular disorders, such as vestibular neuritis and the migraine equivalent, are the leading causes of vertigo. However, even if severe causes of vertigo are rare, clinicians must not miss them. In this review, we discuss the neurological causes of central vertigo in children. The diagnostic approa...
Source: Archives de Pediatrie - August 3, 2023 Category: Pediatrics Authors: Thibault Beretti B éatrice Desnous Source Type: research