The gut microbiota of hand, foot and mouth disease patients demonstrates down ‐regulated butyrate‐producing bacteria and up‐regulated inflammation‐inducing bacteria
This study explored the gut microbiota of children with hand, foot and mouth disease (HFMD).MethodsWe enrolled 15 cases with HFMD admitted to the West China Second Hospital, Sichuan University, China, from July to September 2016 at a median age of three years. The controls were 15 healthy children of a similar age who underwent routine health examinations at the hospital during the same period. Gut microbiota was analysed using high throughput 16S ribosomal deoxyribonucleic acid  sequencing.ResultsThe gut microbiota in the HFMD patients was distinct from the controls. Compared with the controls, the composition of gut...
Source: Acta Paediatrica - November 14, 2018 Category: Pediatrics Authors: Weiran Li, Yu Zhu, Yiyuan Li, Min Shu, Yang Wen, Xiaolin Gao, Chaomin Wan Tags: Regular Article Source Type: research

Bone maturation cannot be used to estimate chronological age in asylum ‐seeking adolescents
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 14, 2018 Category: Pediatrics Authors: Inge Axelsson Tags: A Different View Source Type: research

The impact of childhood bullying on the daily lives of Nordic children and young adolescents
ConclusionThis study found negative impact on the mental health in bullied children and adolescents, which affected several arenas of daily life.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 13, 2018 Category: Pediatrics Authors: M. Kirketerp Krusell, L. Hohw ü, Y. Bjereld, K. Bang Madsen, C. Obel Tags: Regular Article Source Type: research

Major concerns about late hypothermia study
AbstractAn important neonatal hypothermia (HT) trial on hypoxic ‐ischemic‐encephalopathy was published in November 2017 by Laptook and the NICHD group (1). One hundred and sixty‐eight newborn term infants who failed the 6 hour time‐window for HT were recruited by 21 centers over an 8 year period into a trial of HT versus normothermia (NT) if they were>6h and
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: Lars Wall øe, Nils Lid Hjort, Marianne Thoresen Tags: A Different View Source Type: research

Case control study found that primary language disorders were associated to screen exposure at 3.5 ‐6.5 years of age
ConclusionBeing exposed to screens in the morning before school, and rarely or never discussing screen content with parents, meant children were six times more likely to develop primary language disorders.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: M Collet, B Gagni ère, C Rousseau, A Chapron, L Fiquet, C Certain Tags: Regular Article Source Type: research

Commentary on paracetamol in preterm infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: Arne Ohlsson Tags: Short Commentary Source Type: research

Issue Information
Acta Paediatrica, Volume 107, Issue 12, Page 2035-2039, December 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Tags: Issue Information Source Type: research

Highlights in this issue
Acta Paediatrica, Volume 107, Issue 12, Page 2040-2041, December 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Anna K äll, Hugo Lagercrantz Tags: Highlights in this issue Source Type: research

Evaluation of screening for coeliac disease in children with juvenile idiopathic arthritis
ConclusionWe found a point prevalence of CD close to previous described prevalence in the general population of Swedish children. Therefore, general screening for CD in children with JIA is not supported by our data. However, this study shows that asymptomatic CD in children with JIA may be found by screening. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Anders Öman, Tony Hansson, Martin Carlsson, Lillemor Berntson Tags: Regular Article Source Type: research

The return of measles to Europe highlights the need to regain confidence in immunisation
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Leif Dotevall Tags: Editorial Source Type: research

The effect of caffeine loading on cerebral autoregulation in preterm infants
ConclusionWe observed a reduced correlation between MAP and TOI from near ‐infrared spectroscopy following caffeine administration. These findings suggest an acute enhanced capacity for cerebral autoregulation following a loading dose of caffeine in preterm infants, contributing to our understanding of the physiological impact of caffeine therapy.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Jacqueline Huvanandana, Cindy Thamrin, Murray Hinder, Alistair McEwan, Mark Tracy Tags: Regular Article Source Type: research

Snus users had high levels of nicotine, cotinine and 3 ‐hydroxycotinine in their breastmilk, and the clearance was slower than in smoking mothers
ConclusionSnus users had high levels of nicotine and metabolites in their breastmilk and nicotine was found even after 12.5  hours of abstinence. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Felicia Nordenstam, Bo Lundell, Anna ‐Karin Edstedt Bonamy, Pauline Raaschou, Ronny Wickström Tags: Regular Article Source Type: research

The bowel movement characteristics of exclusively breastfed and exclusively formula fed infants differ during the first three months of life
This study of 118 infants was carried out in the maternity ward of the Lille University Jeanne de Flandre Hospital, France, in 2015. The outcomes were the number and consistency of stools and the prevalence of infrequent stools.ResultsAt three months, 84 infants remained and we compared 40 who were exclusively breastfed and 13 who were exclusively formula fed. Daily stool frequency was significantly higher in the breastfed than formula fed infants during the first (4.9  ± 1.7 vs. 2.3 ± 1.6, p 
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Emilie Moretti, Thameur Rakza, B éatrice Mestdagh, Julien Labreuche, Dominique Turck Tags: Regular Article Source Type: research

Growing identification of genetic aetiologies for neonatal ‐onset epilepsies: lessons from the Neonatal Seizure Registry
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 6, 2018 Category: Pediatrics Authors: Amanda G. Sandoval Karamian, Fiona M. Baumer Tags: EBNEO Commentary Source Type: research

Reply from the authors: Additional factors to consider with regard to condensation in  bench studies
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 5, 2018 Category: Pediatrics Authors: Rutger C. Flink, Anton H. Kaam, Frans H. Jongh Source Type: research

AP1S2 ‐truncating variant in a patient with severe neurodevelopmental disorder and cerebral folate deficiency
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Gerarda Cappuccio, Annalaura Torella, Mario Mastrangelo, Claudia Carducci, Vincenzo Nigro, Nicola Brunetti ‐Pierri, Vincenzo Leuzzi Source Type: research

The Doctor ‐Parent Relationship in Pediatrics: trainees’ experiences and perspectives
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Bonnie H Arzuaga, Carter Petty, Annie Janvier Source Type: research

Key considerations prior to nasal high flow deployment in a Peruvian PICU from providers ’ perspectives
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Laura E. Ellington, Elizabeth Jacob ‐Files, Rosario Becerra, Gabriela Mallma, José Tantalean da Fieno, Katie R. Nielsen Source Type: research

Multi ‐centre study found that documentation on resuscitating asphyxiated neonates was often unsatisfactory
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 31, 2018 Category: Pediatrics Authors: Francesco Cavallin, Gaia Pavan, Maria Elena Cavicchiolo, Nicoletta Doglioni, Daniele Trevisanuto Source Type: research

A randomized controlled trial of protocolized music therapy demonstrates developmental milestone acquisition in hospitalized infants
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: L Emery, E Hamm, K Hague, O Chorna, M Moore ‐Clingenpeel, N L Maitre Source Type: research

Four ‐year outcome of randomly assigned lifestyle treatments in primary care of children with obesity
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Christer Forsell, Eva Gronowitz, Yvonne Larsson, Britt ‐Marie Kjellberg, Peter Friberg, Staffan Mårild Source Type: research

High ‐versus low‐dose caffeine in preterm infants: a systematic review and meta‐analysis
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Petter Brattstr öm, Chiara Russo, David Ley, Matteo Bruschettini Source Type: research

What matters most when it comes to vocabulary and language development?
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Jorgen Lous Source Type: research

Cerebral oxygenation and cardiorespiratory stability following liberal transfusion in preterm neonates
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Maria Saito ‐Benz, Clint Gray, Yu‐Chieh Tzeng, Greg Atkinson, Mary J. Berry Source Type: research

Increased surfactant protein ‐D levels in the airways of preterm neonates with sepsis indicated responses to infectious challenges
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Rose ‐Marie A. Mackay, J. Paul Townsend, Jennifer Calvert, Mark Anthony, Andrew R. Wilkinson, Anthony D. Postle, Howard W Clark, David A Todd Source Type: research

Lightning strikes in pregnancy
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Christopher Andrews, Mary Ann Cooper Source Type: research

More severe intellectual disability was found in teenagers than younger children with Down syndrome
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 29, 2018 Category: Pediatrics Authors: Ulrika Wester Oxelgren, Åsa Myrelid, Göran Annerén, Joakim Westerlund, Jan Gustafsson, Elisabeth Fernell Source Type: research

Smart device usage in early childhood is differentially associated with fine motor and language development
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 29, 2018 Category: Pediatrics Authors: Jin ‐Hwa Moon, Sang Yeon Cho, Sung Min Lim, Joo Hyung Roh, Min Sook Koh, Yong Joo Kim, Eunwoo Nam Source Type: research

Systematic review shows that immunising internationally adopted children is a major challenge for primary healthcare
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 28, 2018 Category: Pediatrics Authors: Elisabetta Venturini, Paola Piccini, Chiara Tersigni, Elena Chiappini, Luisa Galli Source Type: research

Comparing a fetus diagnosed with Prader ‐Willi‐syndrome with non‐affected fetuses during light and sound stimulation using 4_D_ultrasound
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 26, 2018 Category: Pediatrics Authors: Nadja Reissland, Akerke Makhmud, Suzanne Froggatt Source Type: research

Paediatric chronic hepatitis b virus infection: are children too tolerant to treat?
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 26, 2018 Category: Pediatrics Authors: Mona El ‐Said El‐Raziky, Hanan Mina Fouad, Noha Saber Abd Elkhalak, Carolyne Morcos Ghobrial, Hanaa Mostafa El‐Karaksy Source Type: research

Further studies of GABA and Glutamate imbalances in autism are important challenges for future research
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 25, 2018 Category: Pediatrics Authors: Elisabeth Fernell Source Type: research

Placental inflammation, lifestyle, maternal and early child sensitization to allergens – the ALADDIN birth cohort
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 19, 2018 Category: Pediatrics Authors: Nikos Papadogiannakis, Maaike Joerink, Erika Rindsj ö, Annika Scheynius, Johan Alm Source Type: research

Longitudinal birth cohort study found that a significant proportion of children had abnormal metabolic profiles and insulin resistance at 6  years of age
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 17, 2018 Category: Pediatrics Authors: Emma Kjellberg, Josefine Roswall, Stefan Bergman, Gerd Almqvist ‐Tangen, Bernt Alm, Jovanna Dahlgren Source Type: research

Pain and sleep disturbances in Rett syndrome and other neurodevelopmental disorders
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 17, 2018 Category: Pediatrics Authors: Gerarda Cappuccio, Pia Bernardo, Enza Raiano, Michele Pinelli, Marianna Alagia, Marcello Esposito, Roberto Della Casa, Pietro Strisciuglio, Nicola Brunetti ‐Pierri, Carmela Bravaccio Source Type: research

The impact and understanding of childhood drowning by a community in  West Bengal, India, and the suggested preventive measures
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 17, 2018 Category: Pediatrics Authors: Caroline Lukaszyk, Srabani Mittal, Medhavi Gupta, Rumeli Das, Rebecca Ivers, Jagnoor Jagnoor Source Type: research

Stool colour test can help to decide which infants with neonatal hyperbilirubinaemia need phototherapy
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 16, 2018 Category: Pediatrics Authors: Srinivasa Murthy Doreswamy, Prajwala Hassan Vasudev, Deepti Thandaveshwara Source Type: research

Sweden and Finland need to improve the support provided for the siblings of children with cancer
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 16, 2018 Category: Pediatrics Authors: M. L övgren, N. Mogensen, A. Harila‐Saari, P.M. Lähteenmäki, U. Kreicbergs Source Type: research

Environmental and birth characteristics as predictors of short stature in early childhood
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 16, 2018 Category: Pediatrics Authors: Ladan Davallow Ghajar, Mark D DeBoer Source Type: research

Follow ‐up study of the early, randomised paracetamol trial to preterm infants, found no adverse reactions at the two‐years corrected age
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 16, 2018 Category: Pediatrics Authors: S Juuj ärvi, H Kallankari, P Pätsi, M Leskinen, T Saarela, M Hallman, O Aikio Source Type: research

Remission of proteinuria in multidrug ‐resistant idiopathic nephrotic syndrome following immunoglobulin immunoadsorption
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 15, 2018 Category: Pediatrics Authors: Elodie Nattes, Dani èle Karaa, Laurène Dehoux, Michel Peuchmaur, Theresa Kwon, Georges Deschênes Source Type: research

Neonatologist Performed Echocardiography offers haemodynamic assessments that go beyond clinical signs and biochemical tests
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 15, 2018 Category: Pediatrics Authors: Eirik Nestaas Source Type: research

National survey reported that French paediatric residents had access to simulation ‐based training but needed more
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 12, 2018 Category: Pediatrics Authors: Chlo é Takvorian, Alain Martinot, Adeline Pierache, Mercedes Jourdain, François Dubos Source Type: research

Review findings included diminished coronary flow reserve after surgery in children with congenital heart disease and inflammation
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 12, 2018 Category: Pediatrics Authors: Erkki Pesonen, Petru Liuba, Elhadi H. Aburawi Source Type: research

What benefits do immunocompromised children get from the varicella zoster virus vaccination?
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 12, 2018 Category: Pediatrics Authors: Anna Nilsson Source Type: research

Oral sweet solution to prevent pain during neonatal hip examination: a randomised controlled trial
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 12, 2018 Category: Pediatrics Authors: Emma Olsson, Miriam Pettersson, Mats Eriksson, Andreas Ohlin Source Type: research

National surveys of UK and Italian neonatal units highlighted significant differences in the use of non ‐invasive respiratory support
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 11, 2018 Category: Pediatrics Authors: Ilia Bresesti, Sanja Zivanovic, Kevin Nicolas Ives, Gianluca Lista, Charles Christoph Roehr Source Type: research

Survey of healthcare professional and parental experience in accessing support for breastfeeding during an acute hospital admission
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 11, 2018 Category: Pediatrics Authors: L V Marino, C S Kidd, N J Davies, P C Thomas, S W Williams, R M Beattie Source Type: research

Higher parental education was associated with better asthma control
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 10, 2018 Category: Pediatrics Authors: Frida Str ömberg Celind, Göran Wennergren, Styliana Vasileiadou, Bernt Alm, Nils Åberg, Emma Goksör Source Type: research

Issue Information
Acta Paediatrica,Volume 107, Issue 11, Page 1839-1843, November 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 10, 2018 Category: Pediatrics Source Type: research