Parental views on the principles for cluster randomised trials involving neonates and infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 26, 2018 Category: Pediatrics Authors: Nicole Thiele, Johanna M. Walz, Verena Lindacher, Silke Mader, Gorm Greisen, The EFCNI Parents Advisory Board Tags: A Different View Source Type: research

Self ‐reported physical activity during leisure time was favourably associated with body composition in Norwegian adolescents
AbstractAimWe studied the cross ‐sectional association between self‐reported physical activity and body composition in adolescents.MethodsThe Norwegian Fit Futures Cohort Study was conducted in the Troms ø and Balsfjord municipalities during 2010‐2011. All 1,117 students in their first year of upper secondary high school were invited to attend an examination at the Clinical Research Unit at the University Hospital of Northern Norway and 93% agreed. After exclusions, we analysed 945 participants ( 51% boys) with a mean age of 16.1 years (range 15.5‐17.5 years) with valid measurements. The associations between...
Source: Acta Paediatrica - November 25, 2018 Category: Pediatrics Authors: Nils Abel Aars, Bjarne K. Jacobsen, Anne ‐Sofie Furberg, Sameline Grimsgaard Tags: Regular Article Source Type: research

Retrospective evaluation of early risk factors in children with different types of micturition disorders
ConclusionLow birth weight might predispose to combined day ‐time‐nocturnal incontinence. We are the first to show that patients suffering from micturition disorders with low birthweight present lower estimated bladder capacity than age‐matched children. Thus, we assume that low birthweight may have strong clinical relevance in children's micturition d isorders.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 25, 2018 Category: Pediatrics Authors: Klaudia Berk, Malgorzata Powirtowska, Adrianna Blahuszewska, Agata Korzeniecka ‐Kozerska Tags: Regular Article Source Type: research

Validation of the international Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries
ConclusionThe GMCD standardised in four diverse countries has appropriate accuracy for identification of children with developmental delay.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 25, 2018 Category: Pediatrics Authors: Ilgi Ozturk Ertem, Vibha Krishnamurthy, Mphelekedzeni C Mulaudzi, Yanina Sguassero, Burcu Bilik, Roopa Srinivasan, Hakan Balta, Ozlem Gulumser, Geliang Gan, Lisa Calvocoressi, Benjamin Johnson, Veronika Shabanova, Brian WC Forsyth Tags: Regular Article Source Type: research

Review and meta ‐analysis found that prenatal folic acid was associated with a 58% reduction in autism but had no effect on mental and motor development
ConclusionAlthough the results should be interpreted with caution, they showed that routine prenatal supplements of folic acid were associated with significantly lower levels of ASD. Further studies are needed to reach a firm conclusion, given the multifactorial aetiology of neurodevelopment.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 22, 2018 Category: Pediatrics Authors: L Iglesias V ázquez, J Canals, V Arija Tags: Review Article Source Type: research

Preliminary results show that males born with hypospadias from 1959 ‐1994 had the same psychiatric morbidity as population‐based controls
ConclusionPsychiatric morbidity was no higher in men with hypospadias than population ‐based controls.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 22, 2018 Category: Pediatrics Authors: Lisa Örtqvist, Hedvig Engberg, Anna Strandqvist, Anna Nordenström, Gundela Holmdahl, Agneta Nordenskjöld, Louise Frisén Tags: Regular Article Source Type: research

Algorithm for predicting threshold retinopathy of prematurity is insufficient and fundus examinations are still needed before 31 weeks
ConclusionWINROP worked better on preterm infants born from 31 weeks onwards or weighing over 1,250g. Fundus examinations remain necessary for infants born earlier or lighter.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 21, 2018 Category: Pediatrics Authors: M Wirth, A Naud, G Caputo, J M Hasco ët Tags: Regular Article Source Type: research

NIRS cerebral patterns in healthy late preterm and term infants are gender ‐ and gestational age‐dependent
AbstractAimNear infrared spectroscopy (NIRS) has been proposed to provide reliable information concerning brain oximetry and tissue activation level in the perinatal period. We aimed to investigate whether NIRS brain patterns in healthy preterm and term infants were gender ‐ and gestational age‐dependent.MethodsWe conducted an observational study in 74 newborns, from consecutive singleton pregnancies, of whom 37 were born at term (male: n=19 female: n=18) and 37 (male: n=18 female: n=19) were preterm. Cerebral oximetry (crSO2) and fractional tissue oxygen extraction (cFTOE), were recorded on the 5th day from birth.Resu...
Source: Acta Paediatrica - November 21, 2018 Category: Pediatrics Authors: Alice Grometto, Francesca Pluchinotta, Francesca Gazzolo, Maria Chiara Strozzi, Diego Gazzolo Tags: Regular Article Source Type: research

Nasal High ‐flow During Neonatal and Infant Transport In Victoria, Australia
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 21, 2018 Category: Pediatrics Authors: V Abraham, B J Manley, L S Owen, M J Stewart, P G Davis, C T Roberts Tags: Brief Report Source Type: research

High versus low dose caffeine in preterm infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 21, 2018 Category: Pediatrics Authors: Roos J S Vliegenthart, Martijn Miedema, Gerard J Hutten, Anton H van Kaam, Wes Onland Tags: Letter Source Type: research

Non ‐reassuring results in agreement trial comparing glass and plastic capillary tubes for neonatal blood gas sampling
AbstractAimTo determine agreement between neonatal capillary blood gases taken with plastic and glass tubes.MethodsAn agreement study was carried out in a regional tertiary neonatal unit. Inpatient babies ≥ 1 Kg were recruited to the study when parents gave consent. After taking the routine glass capillary tube sample, a plastic tube sample was taken and run if the heel continued to bleed. Successful sample pairs were recorded and analysed against pre‐defined acceptable differences. Assessment wa s also made of differences in failure rates between tube types for each parameter.ResultsTwenty ‐eight babies provided 13...
Source: Acta Paediatrica - November 20, 2018 Category: Pediatrics Authors: Kristin Tanney, Ajit Mahaveer, Karen Dockery, Nicola Booth, Carol A Chadwick, Chris M Chaloner, Azita Rajai Tags: Regular Article Source Type: research

Voriconazole ‐induced QTc prolongation in a pediatric population
AbstractAimTo evaluate Corrected QT (QTc) interval prolongation (QTcP) in pediatric patients treated with voriconazole and identify its associated risk factors in this setting.MethodsClinical, voriconazole ‐related, and corrected QT interval (QTc) data were collected retrospectively from the electronic medical records of voriconazole‐treated pediatric patients attending a large tertiary medical center in 2011‐2016 who underwent electrocardiography before and during therapy. Paired comparison of QTc intervals before and during voriconazole treatment was performed, adjusted for concurrent medications, electrolyte distu...
Source: Acta Paediatrica - November 20, 2018 Category: Pediatrics Authors: Y Pasternak, N Shechter, R Loebstein, N Markovits, I Gueta, H Halkin, H Yarden ‐Bilavsky Tags: Regular Article Source Type: research

Sex specific actions of drugs in preterm infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 20, 2018 Category: Pediatrics Authors: Claudia Roll, Patrizia Kutz, Christoph B ührer Tags: A Different View Source Type: research

The price of life: the impact of cost on decision ‐making for extremely premature neonates in China
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 20, 2018 Category: Pediatrics Authors: Jonathan M. Fanaroff Tags: Editorial Source Type: research

Multicentre study found that documentation on resuscitating asphyxiated neonates was often unsatisfactory
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 20, 2018 Category: Pediatrics Authors: Francesco Cavallin, Gaia Pavan, Maria Elena Cavicchiolo, Nicoletta Doglioni, Daniele Trevisanuto Tags: Brief Report Source Type: research

Placental inflammation, lifestyle, maternal and early child sensitisation to allergens – the assessment of lifestyle and allergic disease during infancy birth cohort
ConclusionOur data do not support the hypothesis that the increased risk for sensitisation of a child when the mother is allergic is mediated via placental inflammation. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 19, 2018 Category: Pediatrics Authors: Nikos Papadogiannakis, Maaike Joerink, Erika Rindsj ö, Annika Scheynius, Johan Alm Tags: Regular Article Source Type: research

Dealing with the sharp end of ingested foreign bodies
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 19, 2018 Category: Pediatrics Authors: Yuan Li Ping, Vally Mohammed, Nadia Maniraj, Roxanne Ramnarain, Mpilenhle Pearl Ngcamu, Mohammed.S.S. Al Bulushi, Gui Ming Tags: Brief Report Source Type: research

Spanish survey on follow ‐up programmes for children born very preterm
ConclusionAlthough Spain has a nationwide health system that provides universal health coverage, we found that follow ‐up care for children born very preterm/very low birth weight is not equitable. Nearly half of paediatric residents receive no training in follow up for this high‐risk population.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 17, 2018 Category: Pediatrics Authors: Carmen Rosa Pall ás‐Alonso, Begoña Loureiro, Javier De la Cruz Bértolo, Pilar García, Gemma Ginovart, Ana Jiménez, Yolanda Martín, Javier Soriano, María José Torres, Máximo Vento Tags: Regular Article Source Type: research

The gut microbiota of hand, foot and mouth disease patients demonstrates down ‐regulated butyrate‐producing bacteria and up‐regulated inflammation‐inducing bacteria
This study explored the gut microbiota of children with hand, foot and mouth disease (HFMD).MethodsWe enrolled 15 cases with HFMD admitted to the West China Second Hospital, Sichuan University, China, from July to September 2016 at a median age of three years. The controls were 15 healthy children of a similar age who underwent routine health examinations at the hospital during the same period. Gut microbiota was analysed using high throughput 16S ribosomal deoxyribonucleic acid  sequencing.ResultsThe gut microbiota in the HFMD patients was distinct from the controls. Compared with the controls, the composition of gut...
Source: Acta Paediatrica - November 14, 2018 Category: Pediatrics Authors: Weiran Li, Yu Zhu, Yiyuan Li, Min Shu, Yang Wen, Xiaolin Gao, Chaomin Wan Tags: Regular Article Source Type: research

Bone maturation cannot be used to estimate chronological age in asylum ‐seeking adolescents
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 14, 2018 Category: Pediatrics Authors: Inge Axelsson Tags: A Different View Source Type: research

The impact of childhood bullying on the daily lives of Nordic children and young adolescents
ConclusionThis study found negative impact on the mental health in bullied children and adolescents, which affected several arenas of daily life.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 13, 2018 Category: Pediatrics Authors: M. Kirketerp Krusell, L. Hohw ü, Y. Bjereld, K. Bang Madsen, C. Obel Tags: Regular Article Source Type: research

Major concerns about late hypothermia study
AbstractAn important neonatal hypothermia (HT) trial on hypoxic ‐ischemic‐encephalopathy was published in November 2017 by Laptook and the NICHD group (1). One hundred and sixty‐eight newborn term infants who failed the 6 hour time‐window for HT were recruited by 21 centers over an 8 year period into a trial of HT versus normothermia (NT) if they were>6h and
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: Lars Wall øe, Nils Lid Hjort, Marianne Thoresen Tags: A Different View Source Type: research

Case control study found that primary language disorders were associated to screen exposure at 3.5 ‐6.5 years of age
ConclusionBeing exposed to screens in the morning before school, and rarely or never discussing screen content with parents, meant children were six times more likely to develop primary language disorders.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: M Collet, B Gagni ère, C Rousseau, A Chapron, L Fiquet, C Certain Tags: Regular Article Source Type: research

Commentary on paracetamol in preterm infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 11, 2018 Category: Pediatrics Authors: Arne Ohlsson Tags: Short Commentary Source Type: research

Issue Information
Acta Paediatrica, Volume 107, Issue 12, Page 2035-2039, December 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Tags: Issue Information Source Type: research

Highlights in this issue
Acta Paediatrica, Volume 107, Issue 12, Page 2040-2041, December 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Anna K äll, Hugo Lagercrantz Tags: Highlights in this issue Source Type: research

Evaluation of screening for coeliac disease in children with juvenile idiopathic arthritis
ConclusionWe found a point prevalence of CD close to previous described prevalence in the general population of Swedish children. Therefore, general screening for CD in children with JIA is not supported by our data. However, this study shows that asymptomatic CD in children with JIA may be found by screening. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Anders Öman, Tony Hansson, Martin Carlsson, Lillemor Berntson Tags: Regular Article Source Type: research

The return of measles to Europe highlights the need to regain confidence in immunisation
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 9, 2018 Category: Pediatrics Authors: Leif Dotevall Tags: Editorial Source Type: research

The effect of caffeine loading on cerebral autoregulation in preterm infants
ConclusionWe observed a reduced correlation between MAP and TOI from near ‐infrared spectroscopy following caffeine administration. These findings suggest an acute enhanced capacity for cerebral autoregulation following a loading dose of caffeine in preterm infants, contributing to our understanding of the physiological impact of caffeine therapy.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Jacqueline Huvanandana, Cindy Thamrin, Murray Hinder, Alistair McEwan, Mark Tracy Tags: Regular Article Source Type: research

Snus users had high levels of nicotine, cotinine and 3 ‐hydroxycotinine in their breastmilk, and the clearance was slower than in smoking mothers
ConclusionSnus users had high levels of nicotine and metabolites in their breastmilk and nicotine was found even after 12.5  hours of abstinence. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Felicia Nordenstam, Bo Lundell, Anna ‐Karin Edstedt Bonamy, Pauline Raaschou, Ronny Wickström Tags: Regular Article Source Type: research

The bowel movement characteristics of exclusively breastfed and exclusively formula fed infants differ during the first three months of life
This study of 118 infants was carried out in the maternity ward of the Lille University Jeanne de Flandre Hospital, France, in 2015. The outcomes were the number and consistency of stools and the prevalence of infrequent stools.ResultsAt three months, 84 infants remained and we compared 40 who were exclusively breastfed and 13 who were exclusively formula fed. Daily stool frequency was significantly higher in the breastfed than formula fed infants during the first (4.9  ± 1.7 vs. 2.3 ± 1.6, p 
Source: Acta Paediatrica - November 7, 2018 Category: Pediatrics Authors: Emilie Moretti, Thameur Rakza, B éatrice Mestdagh, Julien Labreuche, Dominique Turck Tags: Regular Article Source Type: research

Growing identification of genetic aetiologies for neonatal ‐onset epilepsies: lessons from the Neonatal Seizure Registry
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 6, 2018 Category: Pediatrics Authors: Amanda G. Sandoval Karamian, Fiona M. Baumer Tags: EBNEO Commentary Source Type: research

Reply from the authors: Additional factors to consider with regard to condensation in  bench studies
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 5, 2018 Category: Pediatrics Authors: Rutger C. Flink, Anton H. Kaam, Frans H. Jongh Source Type: research

AP1S2 ‐truncating variant in a patient with severe neurodevelopmental disorder and cerebral folate deficiency
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Gerarda Cappuccio, Annalaura Torella, Mario Mastrangelo, Claudia Carducci, Vincenzo Nigro, Nicola Brunetti ‐Pierri, Vincenzo Leuzzi Source Type: research

The Doctor ‐Parent Relationship in Pediatrics: trainees’ experiences and perspectives
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Bonnie H Arzuaga, Carter Petty, Annie Janvier Source Type: research

Key considerations prior to nasal high flow deployment in a Peruvian PICU from providers ’ perspectives
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - November 1, 2018 Category: Pediatrics Authors: Laura E. Ellington, Elizabeth Jacob ‐Files, Rosario Becerra, Gabriela Mallma, José Tantalean da Fieno, Katie R. Nielsen Source Type: research

Multi ‐centre study found that documentation on resuscitating asphyxiated neonates was often unsatisfactory
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 31, 2018 Category: Pediatrics Authors: Francesco Cavallin, Gaia Pavan, Maria Elena Cavicchiolo, Nicoletta Doglioni, Daniele Trevisanuto Source Type: research

A randomized controlled trial of protocolized music therapy demonstrates developmental milestone acquisition in hospitalized infants
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: L Emery, E Hamm, K Hague, O Chorna, M Moore ‐Clingenpeel, N L Maitre Source Type: research

Four ‐year outcome of randomly assigned lifestyle treatments in primary care of children with obesity
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Christer Forsell, Eva Gronowitz, Yvonne Larsson, Britt ‐Marie Kjellberg, Peter Friberg, Staffan Mårild Source Type: research

High ‐versus low‐dose caffeine in preterm infants: a systematic review and meta‐analysis
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Petter Brattstr öm, Chiara Russo, David Ley, Matteo Bruschettini Source Type: research

What matters most when it comes to vocabulary and language development?
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Jorgen Lous Source Type: research

Cerebral oxygenation and cardiorespiratory stability following liberal transfusion in preterm neonates
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Maria Saito ‐Benz, Clint Gray, Yu‐Chieh Tzeng, Greg Atkinson, Mary J. Berry Source Type: research

Increased surfactant protein ‐D levels in the airways of preterm neonates with sepsis indicated responses to infectious challenges
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Rose ‐Marie A. Mackay, J. Paul Townsend, Jennifer Calvert, Mark Anthony, Andrew R. Wilkinson, Anthony D. Postle, Howard W Clark, David A Todd Source Type: research

Lightning strikes in pregnancy
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 30, 2018 Category: Pediatrics Authors: Christopher Andrews, Mary Ann Cooper Source Type: research

More severe intellectual disability was found in teenagers than younger children with Down syndrome
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 29, 2018 Category: Pediatrics Authors: Ulrika Wester Oxelgren, Åsa Myrelid, Göran Annerén, Joakim Westerlund, Jan Gustafsson, Elisabeth Fernell Source Type: research

Smart device usage in early childhood is differentially associated with fine motor and language development
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 29, 2018 Category: Pediatrics Authors: Jin ‐Hwa Moon, Sang Yeon Cho, Sung Min Lim, Joo Hyung Roh, Min Sook Koh, Yong Joo Kim, Eunwoo Nam Source Type: research

Systematic review shows that immunising internationally adopted children is a major challenge for primary healthcare
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 28, 2018 Category: Pediatrics Authors: Elisabetta Venturini, Paola Piccini, Chiara Tersigni, Elena Chiappini, Luisa Galli Source Type: research

Comparing a foetus diagnosed with Prader –Willi syndrome with non‐affected foetuses during light and sound stimulation using 4D ultrasound
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 26, 2018 Category: Pediatrics Authors: Nadja Reissland, Akerke Makhmud, Suzanne Froggatt Tags: Brief Report Source Type: research

Comparing a fetus diagnosed with Prader ‐Willi‐syndrome with non‐affected fetuses during light and sound stimulation using 4_D_ultrasound
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 26, 2018 Category: Pediatrics Authors: Nadja Reissland, Akerke Makhmud, Suzanne Froggatt Source Type: research

Paediatric chronic hepatitis b virus infection: are children too tolerant to treat?
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - October 26, 2018 Category: Pediatrics Authors: Mona El ‐Said El‐Raziky, Hanan Mina Fouad, Noha Saber Abd Elkhalak, Carolyne Morcos Ghobrial, Hanaa Mostafa El‐Karaksy Source Type: research