What are Some Risk Factors for Hypoxic-Ischemic Encephalopathy Outcomes?

Discussion “Neonatal encephalopathy, manifesting as altered responsiveness, seizures, apnea and abnormal muscle tone and reflexes, resulting from hypoxic-ischemic injury is termed hypoxic-ischemic encephalopathy (HIE).” Neonatal encephalopathy can be associated with other problems including stroke, hemorrhage, infection, pre-term brain injury and hypoglycemia as some examples. Sometimes more than one of these entities occurs simultaneously such as hypoglycemia and HIE. HIE can result in long-term neurological problems including motor, behavioral, and cognitive problems that can become apparent even years later. HIE occurs in 1-3/1000 live births. Causes of HIE can be broadly separated into two general types: Acute catastrophic asphyxia is associated with about 25% of cases and is associated with placental abruption, uterine rupture, cord prolapse, fetal entrapment and cord problems Chronic which appears to be associated with about 66% of cases where they are “repeated but relatively short periods of deep hypoxia” and is associated with the “direction function of the inherent intermittent “asphyxia” of labor.” Another ~10% of moderate to severe HIE appears to have problems preceding labor onset with abnormal fetal heart rate and associated preceding fetal compromise. Although labor contractions cause intermittently impaired uteroplacental perfusion, authors note the “In face, it appears that the fetus is spectacularly goo...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news