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Nutrition: Diets
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Total 302 results found since Jan 2013.
Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats
This report investigates the role of PKa on hemorrhage and hypertension in stroke-prone spontaneously hypertensive rats (SHRSP). SHRSP were fed with a high salt –containing stroke-prone diet to increase blood pressure and induce intracerebral hemorrhage. The roles of PKa on blood pressure, hemorrhage, and survival in SHRSP were examined in rats receiving a PKa inhibitor or plasma prekallikrein antisense oligonucleotide (PK ASO) compared with rats receivin g control ASO. Effects on PKa on the proteolytic cleavage of atrial natriuretic peptide (ANP) were analyzed by tandem mass spectrometry. We show that SHRSP on high-salt...
Source: Translational Stroke Research - July 9, 2021 Category: Neurology Source Type: research
N-Pep-12 supplementation after ischemic stroke positively impacts frequency domain QEEG
ConclusionA 90-day, 90 mg daily administration of N-Pep-12 had significant impact on some QEEG indicators in patients after supratentorial ischemic stroke, confirming possible enhancement of post-stroke neurorecovery. Further research is needed to consolidate our findings.
Source: Neurological Sciences - June 25, 2021 Category: Neurology Source Type: research
Five Unapproved Drugs Found in Cognitive Enhancement Supplements
Conclusions
Over-the-counter cognitive enhancement supplements may contain multiple unapproved drugs. The health effects of consuming untested combinations of unapproved drugs at unpredictable dosages without clinician oversight in supplements are unknown.
Source: Neurology Clinical Practice - June 7, 2021 Category: Neurology Authors: Cohen, P. A., Avula, B., Wang, Y. H., Zakharevich, I., Khan, I. Tags: Other cerebrovascular disease/ Stroke, All Cognitive Disorders/Dementia, Other toxicology Research Source Type: research
Stroke Prevention: Little-Known and Neglected Aspects
Combining available therapies has the potential to reduce the risk of stroke by 80% or more. A comprehensive review of all aspects of stroke prevention would be very lengthy; in this narrative review, we focus on some aspects of stroke prevention that are little-known and/or neglected. These include the following: (1) implementation of a Mediterranean diet; (2) B vitamins to lower homocysteine; (3) coordinated approaches to smoking cessation; (4) intensive lipid-lowering therapy; (5) lipid lowering in the elderly; (6) physiologically individualized therapy for hypertension based on renin/aldosterone phenotyping; (7) avoidi...
Source: Cerebrovascular Diseases - May 27, 2021 Category: Neurology Source Type: research
Secondary Prevention of Stroke: Study Protocol for a Telehealth-Delivered Physical Activity and Diet Pilot Randomized Trial (ENAbLE-Pilot)
Conclusion: This trial will produce evidence for the feasibility, safety, and potential effect of telehealth-delivered PA and DIET interventions for people with stroke. Results will inform development of an appropriately powered trial to test effectiveness to reduce major risk factors for recurrent stroke.Trial registration: ACTRN12620000189921.Cerebrovasc Dis
Source: Cerebrovascular Diseases - April 23, 2021 Category: Neurology Source Type: research
High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke
In this study, whe...
Source: Journal of Neuroinflammation - April 12, 2021 Category: Neurology Authors: Mengyan Hu, Yinyao Lin, Xuejiao Men, Shisi Wang, Xiaobo Sun, Qiang Zhu, Danli Lu, Sanxin Liu, Bingjun Zhang, Wei Cai and Zhengqi Lu Tags: Research Source Type: research
Dietary Oily Fish Intake is Inversely Associated with Severity of White Matter Hyperintensities of Presumed Vascular Origin. A Population-Based Study in Frequent Fish Consumers of Amerindian Ancestry
Oily fish is a major dietary source of omega-3 polyunsaturated fatty acids and other nutrients that may reduce the expression of cerebral small vessel disease (cSVD) biomarkers, including white matter hyperintensities (WMH) of presumed vascular origin. However, information on this relationship is limited. We aimed to assess the association between oily fish intake and WMH severity in a population of frequent fish consumers.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2021 Category: Neurology Authors: Oscar H. Del Brutto, Bettsy Y. Recalde, Robertino M. Mera Source Type: research
Impact of Mediterranean Diet prior to Stroke on the Prognosis of Patients Undergoing Endovascular Treatment
Conclusions: Our study suggests that some components of MeDiet, such as olive oil and wine consumption, are related to better prognosis after stroke. More studies are needed to confirm these findings.Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 17, 2021 Category: Neurology Source Type: research
Cardiovascular disease risk, awareness, and treatment in people with epilepsy
CONCLUSIONS: Participants with epilepsy had increased ASCVD risk, despite similar or better awareness, treatment, and control of individual risk factors such as diabetes and hypertension. Our results suggest that epilepsy is associated with numerous health behaviors leading to cardiovascular disease, though the causal pathway is complex as these variables (income, depression, diet, exercise, smoking) generally served as confounders rather than mediators.PMID:33690068 | DOI:10.1016/j.yebeh.2021.107878
Source: Epilepsy and Behaviour - March 10, 2021 Category: Neurology Authors: Samuel W Terman Carole E Aubert Chloe E Hill Jeremy Skvarce James F Burke Scott Mintzer Source Type: research
A Sharp Decline in Burden of Stroke in Rural China During COVID-19 Pandemic
This study aimed to explore trends in the burden from stroke associated with home quarantine during the COVID-19 pandemic. Patients with a first-ever stroke registered between January 1 and April 20 from 2010 to 2020 were included in this study. We compared the incidence and the rates of mortality, hospitalization, and diagnosis by neuroimaging for first-ever stroke among a low-income population in rural China during the study periods. Overall, 377 first-ever stroke patients were analyzed in this study period; men accounted for 59.2%. Compared with 2019, the incidence of first-ever stroke was 73.5% lower in 2020 (P < 0....
Source: Frontiers in Neurology - January 25, 2021 Category: Neurology Source Type: research
The role of diet in secondary stroke prevention
Publication date: Available online 18 December 2020Source: The Lancet NeurologyAuthor(s): Coralie English, Lesley MacDonald-Wicks, Amanda Patterson, John Attia, Graeme J Hankey
Source: The Lancet Neurology - December 19, 2020 Category: Neurology Source Type: research
Microglia depletion increase brain injury after acute ischemic stroke in aged mice.
In conclusion, PLX5622 and AFS98 treatment depleted microglia in aged animals but resulted in increased neuroinflammation after ischemic stroke.
PMID: 33221396 [PubMed - as supplied by publisher]
Source: Experimental Neurology - November 19, 2020 Category: Neurology Authors: Lee SM, Hudobenko J, McCullough LD, Chauhan A Tags: Exp Neurol Source Type: research
Recent Insights on the Role of PPAR- β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy
AbstractPeroxisome proliferator-activated receptor (PPAR) β/δ belongs to the family of hormone and lipid-activated nuclear receptors, which are involved in metabolism of long-chain fatty acids, cholesterol, and sphingolipids. Similar to PPAR-α and PPAR-γ, PPAR-β/δ also acts as a transcription factor activated by dietary lipids and endogenous ligands, such as long-chain saturated and polyunsaturated fatty acids, and selected lipid metabolic products, such as eicosanoids, leukotrienes, lipoxins, and hydroxyeicosatetraenoic acids. Together with other PPARs, PPAR-β/δ displays transcriptional activity through interactio...
Source: NeuroMolecular Medicine - November 18, 2020 Category: Neurology Source Type: research
Coffee Consumption and Stroke Risk: Evidence from a Systematic Review and Meta-Analysis of more than 2.4 Million Men and Women
Stroke remains the leading cause of disability and mortality globally. Based on the Global Burden of Disease Study 2016, it was estimated that there were 13.7 million new stroke cases, 5.5 million deaths, 80.1 million prevalent cases, and 116.4 million disability-adjusted life-years.1 About 75% of stroke cases are ischemic, whereas the remaining cases are hemorrhagic.2 Stroke incidence increases with age. Well-known risk factors for stroke include personal history of hypertension, diabetes and cardiac diseases, unhealthy behavioral factors (heavy cigarette consumption, less physical inactivity, poor diet), and serious environmental risks.
Source: Journal of Stroke and Cerebrovascular Diseases - November 11, 2020 Category: Neurology Authors: Chuan Shao, Hui Tang, Xiaoya Wang, Jiaquan He Source Type: research
