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Total 27990 results found since Jan 2013.

Iatrogenic Air Embolisms During Endovascular Interventions: Impact of Origin and Number of Air Bubbles on Cerebral Infarctions
ConclusionIatrogenic AEs originating at the ascending aorta cause a similar number and pattern of cerebral infarctions compared to those with origin at the carotid artery. These findings underline the relevance and potential risk of AE occurring during endovascular interventions at the aortic valve and ascending aorta.
Source: Clinical Neuroradiology - September 4, 2023 Category: Neurology Source Type: research

Endovascular Treatment for Acute Isolated Internal Carotid Artery Occlusion
ConclusionAlthough the benefit on functional outcome did not reach statistical significance, the results for NIHSS score improvement, and safety support the use of EVT in patients with stroke due to isolated ICA occlusion.
Source: Clinical Neuroradiology - September 4, 2023 Category: Neurology Source Type: research

Frequency and predictors of poststroke epilepsy after mechanical thrombectomy for large vessel occlusion stroke: results from a multicenter cohort study
ConclusionIn our study, patients with large vessel occlusion stroke receiving MT had a 9% prevalence of PSE over a median follow-up period of 6.5 years. Besides larger infarct size, presence of cerebral microbleeds on brain MRI predicted PSE occurrence.
Source: Journal of Neurology - September 2, 2023 Category: Neurology Source Type: research

Association of Ferroptosis with Severity and Outcomes in Acute Ischemic Stroke Patients Undergoing Endovascular Thrombectomy: A Case-control Study
AbstractFerroptosis, an iron-dependent form of cell death, is characterized by intracellular accumulation of iron and reactive oxygen species-induced lipid peroxidation. Animal experiments have shown the important roles of ferroptosis in ischemic stroke, but the evidence in human stroke is insufficient. This prospective study evaluated the associations between plasma ferroptosis biomarkers at hyperacute stage and long-term outcomes in patients with acute ischemic stroke undergoing endovascular thrombectomy (EVT). The plasma samples were collected immediately before and after EVT (T1 and T2) and at 24 h (T3) for the 126 s...
Source: Molecular Neurobiology - September 1, 2023 Category: Neurology Source Type: research

SLC26A11 Inhibition Reduces Oncotic Neuronal Death and Attenuates Stroke Reperfusion Injury
In this study, electrophysiological properties of chloride current in primary cultured neurons were characterized using low chloride solution, 4,4 ′-diisothiocyano-2,2′-stilbenedisulfonic acid, and SLC26A11-specific siRNA under physiological conditions or ATP-depleted conditions. In vivo effect of SLC26A11 was evaluated on a rat stroke reperfusion model. We found that SLC26A11 mRNA in primary cultured neurons was upregulated as early as 6 h after oxygen glucose deprivation, and later, the protein level was elevated accordingly. Blockade of SLC26A11 activity could reduce chloride entry and attenuate hypoxia-induced ne...
Source: Molecular Neurobiology - September 1, 2023 Category: Neurology Source Type: research

A modified murine photothrombotic stroke model: a minimally invasive and reproducible cortical and sub-cortical infarct volume and long-term deficits
In conclusion, this modified model helps to understand stroke pathogenesis and minimize the animals' numbers which help to increase the scientific and statistical potential in pre-clinical studies.PMID:37656197 | DOI:10.1007/s00221-023-06696-5
Source: Brain Research - September 1, 2023 Category: Neurology Authors: Mohd Salman Saifudeen Ismael Tauheed Ishrat Source Type: research

Neutrophil-to-lymphocyte ratio at admission is a risk factor for in-hospital gastrointestinal bleeding in acute ischemic stroke patients after dual antiplatelet therapy: A case control study
Gastrointestinal bleeding is a clinically important complication in acute ischemic stroke patients after dual antiplatelet therapy. The present study was to explore the association between neutrophil-to-lymphocyte ratio (NLR) and in-hospital gastrointestinal bleeding in acute ischemic stroke (AIS) patients who had received dual antiplatelet therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2023 Category: Neurology Authors: Jiaming Huang, Foqiang Liao, Yeting Luo, Xu Shu Source Type: research

Death and ADL Dependency After Scoring Zero on the NIHSS: A Swedish Retrospective Registry-Based Study
Discussion One of 17 patients has either died or become ADL-dependent 3 months after a 0-NIHSS stroke, stressing that these strokes are not always benign. Older and physically inactive patients are at greater risk of an adverse outcome.
Source: Neurology Clinical Practice - September 1, 2023 Category: Neurology Authors: Darehed, D., Reinholdsson, M., Viktorisson, A., Abzhandadze, T., Sunnerhagen, K. S. Tags: Outcome research, All Cerebrovascular disease/Stroke, Cohort studies Research Article Source Type: research

Oxidative stress and early mortality in acute ischemic stroke: A prospective cohort study
CONCLUSION: MDA serum level was significantly higher in non-survivors than in survivors patients, so MDA could be used as a predictor for early mortality and short-term outcome of cases with AIS.PMID:37652662 | DOI:10.1080/01616412.2023.2252284
Source: Neurological Research - August 31, 2023 Category: Neurology Authors: Eman A Elhamrawy Heba Shoman Hayam Abdel-Tawab Eshak I Bahbah Rasha Sobhy Elattar Naema R Hussein Marwa Sonbol Asmaa AbdElghany Elsheikh Source Type: research

Neuroanatomical Correlates of Cognitive Impairment following Basal Ganglia-Thalamic Post-Hemorrhagic Stroke: Uncovering Network-Wide Alterations in Hemispheric Gray Matter Asymmetry
In conclusion, PhSCI patients exhibited network-wide cortical GM losses, distal to subcortical hemorrhagic lesions, and hemisphere asymmetry changes. These changes appear to predict rTMS-related cognitive improvements, suggesting that even subcortical focal lesions can lead to alterations in distal cortical neuroanatomical architecture. Our preliminary findings provide new insights into the neuroanatomical basis of PhSCI.PMID:37652090 | DOI:10.1016/j.brainres.2023.148559
Source: Brain Research - August 31, 2023 Category: Neurology Authors: Huan Wang Minhua Yu Jinxia Ren Xiaoli Zhong Dan Xu Lei Gao Haibo Xu Source Type: research

A right convergence area of the prefrontal lobe is involved in the improvement of semantic fluency in patients with post-stroke aphasia
CONCLUSION: The improvement of semantic fluency in subacute PSA patients may require the participation of the right convergence area of the prefrontal lobe.PMID:37651207 | DOI:10.1080/10749357.2023.2253632
Source: Topics in Stroke Rehabilitation - August 31, 2023 Category: Neurology Authors: Tao Feng Chao Zhang Siwei Xu Lingmin Wang Kai Xu Zhiyuan Xie Jie Xiang Weiwei Chen Source Type: research

Effect of using an 8-figure shoulder brace on arm swing angle and gait parameters in chronic stroke patients: a pilot randomized controlled study
CONCLUSIONS: This study demonstrated that 8-FSBTT training, combined with standard physiotherapy, improved Arm swing angle, gait speed, cadence, and both side stride lengths in the chronic stroke patients.PMID:37651200 | DOI:10.1080/10749357.2023.2253626
Source: Topics in Stroke Rehabilitation - August 31, 2023 Category: Neurology Authors: Donghwan Park Source Type: research

20  kDa isoform of connexin-43 augments spatial reorganization of the brain endothelial junctional complex and lesion leakage in cerebral cavernous malformation type-3
This study highlights generation of potential defects at the CCM3-affected brain endothelial barrier which may underlie prolonged vascular leakiness.PMID:37652184 | DOI:10.1016/j.nbd.2023.106277
Source: Neurobiology of Disease - August 31, 2023 Category: Neurology Authors: Chelsea M Phillips Allison M Johnson Svetlana M Stamatovic Richard F Keep Anuska V Andjelkovic Source Type: research

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