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Specialty: Neurology
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Tele-rehabilitation on independence in activities of daily living after stroke: A Matched Case-Control Study
Rehabilitation is one of the most important aspects of care following a stroke, leading to better recovery and higher levels of independence.1 Previous studies have shown that 25% –74% of patients who had a stroke need assistance from caregivers for activities of daily living (ADLs), with quality of life (of both patients and caregivers) being heavily impacted due to this.2 The assessment of ADLs in adults who have had a stroke has recently been reported as a crucial moment for the entire field of rehabilitation3 and improving ADLs is always taken as an essential aim of rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2023 Category: Neurology Authors: Alejandro Garc ía-Rudolph, Mark Andrew Wright, Narda Murillo, Eloy Opisso, Josep Medina Source Type: research
Treatment effects of low-frequency repetitive transcranial magnetic stimulation combined with motor relearning procedure on spasticity and limb motor function in stroke patients
ConclusionLow-frequency rTMS combined with MRP had better efficacy on spasticity and motor function in stroke patients with hemiparesis than MRP alone.
Source: Frontiers in Neurology - August 11, 2023 Category: Neurology Source Type: research
Skin capillary amylin deposition resembles brain amylin vasculopathy in rats
Human amylin is a 37 amino-acid pancreatic peptide that forms neuro-toxic aggregates that deposit in the endothelium of brain capillaries of patients with diabetes, potentially contributing to cerebral small vessel ischemic injury. Pathogenic amylin also deposits in the capillary endothelium in other organs, including the skin. The aim of this study was to test the hypothesis that skin capillary amylin deposition correlates with cerebral small vessel amylin deposition, potentially providing a clinically useful marker of cerebral amylin deposition.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2023 Category: Neurology Authors: Saurav Das, Nirmal Verma, Larry B. Goldstein, Florin Despa Source Type: research
Ticagrelor versus clopidogrel after intracranial stent angioplasty: a real-world study
ConclusionIn our study involving patients with acute ischemic stroke who had undergone intracranial stenting, aspirin-ticagrelor was not found to be superior to aspirin-clopidogrel in reducing the rate of ischemic vascular events. The risk of bleeding did not differ between the two groups. Aspirin-ticagrelor does not lower total restenosis and symptomatic restenosis risk at follow-up.
Source: Frontiers in Neurology - August 11, 2023 Category: Neurology Source Type: research
Neuroprotective Effects of Phenolic Antioxidant Tert-butylhydroquinone (tBHQ) in Brain Diseases
This article reviews the effects of tBHQ on neuroinflammation and oxidative stress in recent years and looks into how tBHQ inhibits neuroinflammation and oxidative stress through human, animal, and cell experiments to play a neuroprotective role in Alzheimer’s disease (AD), stroke, depression, and Parkinson’s disease (PD). It is anticipated that this article will be useful as a reference for upcoming research and the creation of drugs to treat brain diseases.
Source: Molecular Neurobiology - August 10, 2023 Category: Neurology Source Type: research
Antiplatelet therapy in Neurointervention
Semin Neurol DOI: 10.1055/s-0043-1771383The aim of this review is to provide an overview of the use of antiplatelet medication in neurointervention, with a focus on the clinical indications for antiplatelet use in both preventing and reducing platelet aggregation. This review will cover current antiplatelet medications, pharmacokinetics, and pharmacodynamics. We will provide an overview of different endovascular devices and discuss the antiplatelet regimes in neurointervention, highlighting gaps in evidence and scope for future studies.Two randomized controlled trials have evaluated antiplatelet use in the setting of acute...
Source: Seminars in Neurology - August 10, 2023 Category: Neurology Authors: Ma, Alice Detaram, Harshil Dharamdasani Steinfort, Brendan Harrington, Tim Nguyen, Thanh N. Abdalkader, Mohamad Siopis, George Bath, Philip M. Dhillon, Permesh Singh Podlasek, Anna Qureshi, Adnan I. Qiu, Zhongming Krishnan, Kailash Tags: Review Article Source Type: research
Ipsilateral and contralateral carotid stenosis contribute to the outcome of reperfusion treatment for ischemic stroke
DiscussionAccording to our findings, ICS and CCS negatively influence AIS patients' outcome treated by interventional therapies. ICS might exert an unfavorable effect both by cerebral hypoperfusion and by continuous microembolization toward ischemic area, while CCS is probable involved in reducing the collateral circles effectiveness. The importance of early carotid stenosis detection and treatment should then be reevaluated not only to manage the prevention approaches but also to obtain insights about post-stroke treatment strategies efficacy.
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
Train-your-brain program to reduce depression, anxiety, and stress in stroke survivors: a pilot community-based cognitive intervention study
DiscussionThe TYB program provided group support and validation, resulting in improved mood and reduced stress among stroke survivors. Cultural collectivism played a significant role in fostering group cohesion. However, the program’s limited focus on caregivers and timing of assessments during the December holidays may have affected the outcomes. The TYB program demonstrated feasibility and potential effectiveness in alleviating psychological distress and enhancing cognitive function among stroke survivors. Future research should explore long-term effects, larger sample sizes, and non-English-speaking populations to enh...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
Endovascular Treatment for Acute Ischemic Stroke in China: a study protocol for a prospective, national, multi-center, registry study
This study plans to enroll a total of 3,000 consecutive patients who received EVT for LVO. All eligible patients are adults aged 18 years or older with acute LVO who received EVT and standard medical treatment according to the Chinese stroke guidelines and local practice.OutcomeThe primary outcome is functional independence (modified Rankin Scale score, mRS ≤ 2) at 90 days. The secondary outcomes include (1) the proportion of patients with mRS scores of 0–1 at 90 days, (2) distribution of mRS at 90 days, (3) changes in National Institutes of Health stroke scale (NIHSS) at 24 h, 48 h, and 12 days or discharge (whichever...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
Comparative efficacy and safety of multiple acupuncture therapies for post stroke cognitive impairment: a network meta-analysis of randomized controlled trials
ConclusionAccording to our Bayesian NMA results, ophthalmic acupuncture plus cognitive training and warm acupuncture plus cognitive training were the most effective acupuncture treatments for improving cognitive function, while scalp acupuncture plus body acupuncture was the best acupuncture treatment for improving the performance of self-care in daily life in patients with PSCI. No serious adverse effects were found in the included studies, and acupuncture treatment appears to be safe and reliable. However, due to the low methodological quality of the included studies, our findings need to be treated with caution. High-qu...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
The effects of Baduanjin on physical function, daily living activities and quality of life in patients with stroke: a systematic review and meta-analysis
CONCLUSIONS: Baduanjin is probably an effective rehabilitation method to improve balance, motor, trunk, neurological functions, daily living activities, and quality of life in stroke patients. However, the result of Baduanjin in improving walking function is unstable, and further high-quality randomized controlled trials are needed to confirm the results.PMID:37555455 | DOI:10.1080/10749357.2023.2238433
Source: Topics in Stroke Rehabilitation - August 9, 2023 Category: Neurology Authors: Lirong Wei Yun Liu Yanan Wang Jiping Bian Zhengyang Song Xiaofeng Liu Shen Wang Source Type: research
