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Total 585 results found since Jan 2013.

E-008 Clinical and Radiographic Outcome of Acute Ischemic Stroke Patient who Presented with Middle Cerebral Artery Occlusion-A Single Center Experience
Conclusions Solitaire retrieval device achieves a very high rate of recanalazitation in acute ischemic stroke with MCA occlusion and results in a good clinical outcome. However, a considerable valuable time is still lost from ER arrival to IR arrival. Patients who required endotracheal intubation at presentation and or had NIHSS 20 or higher are associated with poor outcome despite TICI3 recanalization. Further studied are required. Disclosures Y. Lodi: None. V. Reddy: None. A. Devasenapathy: None. J. Chou: None. K. Shehades: None. K. Sethi: None. D. Galyon: None. S. Bajwa: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Lodi, Y., Reddy, V., Devasenapathy, A., Chou, J., Shehades, K., Sethi, K., Galyon, D., Bajwa, S. Tags: Electronic poster abstracts Source Type: research

Neuroimaging findings of post-thrombolysis cerebral hemorrhage in acute ischemic stroke (P6.238)
Conclusion: The most common pattern of hemorrhage observed after IV-tPA in acute ischemic stroke was petechial hemorrhagic transformation of ischemic infarct, which is most suggestive of bleeding due to blood-brain breakdown at the site of infarction. Unusual patterns of hemorrhage (such as multiplicity and remote ICH) are rare. Further studies are warranted to better understand the underlying mechanisms of hemorrhagic complications after thrombolysis.Disclosure: Dr. Lee has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Song has nothing to disclose. Dr. Cherian has nothing to disclose. Dr. Conners has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lee, V., Cutting, S., Song, S., Cherian, L., Conners, J. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Revisiting Clinical Utility of Chest Radiography and Electrocardiogram to Determine Ischemic Stroke Subtypes: Special Reference on Vascular Pedicle Width and Maximal P-Wave Duration
Backgrounds: It is often difficult to diagnose stroke subtypes at admission, particularly in sinus rhythm cases. Vascular pedicle width (VPW) on chest X-ray (CXR) and maximal P-wave duration (P-max) on electrocardiogram (ECG) are again realized as useful parameters reflecting intravascular volume and atrial conduction status, respectively. We investigated the utility of VPW and P-max as a tool for differentiating ischemic stroke subtypes. Methods: We studied 343 acute stroke patients showing sinus rhythm on admission. Dividing the patients into cardioembolic (CE) stroke (n = 57) and non-CE (n = 286) groups, we compared cli...
Source: European Neurology - May 22, 2015 Category: Neurology Source Type: research

E-084 proximal versus distal occlusions in the posterior circulation: acute stroke etiology in endovascular therapy
ConclusionsWhile clinically devastating, posterior circulation stroke, may have favorable outcomes if endovascular strategies are targeted to arterial occlusion etiology.DisclosuresM. Nour: None. S. Tateshima: 2; C; Reverse Medical, Stryker Neurovascular, Silkroad Medical, Blockade Medical. G. Duckwiler: 2; C; Sequent Medical, Asahi Medical. R. Jahan: 2; C; Covidien, Medina. N. Gonzalez: None. V. Szeder: None. L. Ai: None. J. Saver: 6; C; Dr. Saver is an employee of the University of California. The University of California, Regents receive funding for Dr. Saver’s services as a scientific consultant. D. Liebeskind: 2...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Nour, M., Tateshima, S., Duckwiler, G., Jahan, R., Gonzalez, N., Szeder, V., Ai, L., Saver, J., Liebeskind, D. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Isolated asymptomatic pulmonary arteriovenous malformation presenting with ischaemic stroke
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Kelly L. Bertram, Anoop Madan, Judith Frayne Young onset stroke is uncommon, and may be due to conditions other than traditional vascular risk factors. A 42-year-old woman with an ischaemic stroke was found to have left atrial bubble study positivity on transthoracic echocardiogram (TTE) suggestive of patent foramen ovale, however she also had low peripheral oxygen saturation. Investigation revealed an isolated pulmonary arteriovenous malformation (PAVM), visible on admission chest radiograph. This can cause embolic ...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research

Outcome Predictors After Successful Intra-Arterial Therapy for Acute Ischemic Stroke (P1.195)
Conclusion: Age, NIHSS score, use of stent retrievers, mode of anesthesia, and symptomatic ICH might affect functional outcome in stroke patients who achieve successful recanalization via intra-arterial therapy. Prospective studies, or a meta-analysis of sub-groups in the recently published prospective trials are needed to confirm the association between those factors, or others, and functional outcome.Disclosure: Dr. Noufal has nothing to disclose. Dr. Mankad has nothing to disclose. Dr. Lakraj has nothing to disclose. Dr. Cox has nothing to disclose. Dr. Shirilla has nothing to disclose. Dr. Sattar has nothing to disclos...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Noufal, M., Mankad, J., Lakraj, A. A., Cox, J.-A., Shirilla, D., Sattar, A., Wazni, W., Sallowm, Y., Lynch, J., Zaidat, O. Tags: Acute Endovascular Therapy: Outcomes and Safety Source Type: research

Comparison of non-stent retriever and stent retriever mechanical thrombectomy devices for the endovascular treatment of acute ischemic stroke.
CONCLUSIONS Stent retriever mechanical thrombectomy devices achieve higher recanalization rates than non-stent retriever devices in acute ischemic stroke with improved clinical and radiographic outcomes and safety. PMID: 27128585 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - April 28, 2016 Category: Neurosurgery Authors: Hentschel KA, Daou B, Chalouhi N, Starke RM, Clark S, Gandhe A, Jabbour P, Rosenwasser R, Tjoumakaris S Tags: J Neurosurg Source Type: research

Simple prediction model for unfavorable outcome in ischemic stroke after intravenous thrombolytic therapy
Conclusion An NIHSS> 12 on arrival, presence of HAS and age> 70 years were predictors of unfavorable outcome at three months in patients with acute ischemic stroke treated with IVT.RESUMO Objetivo Desenvolver um modelo para predizer desfecho desfavor ável em pacientes com acidente vascular cerebral isquêmico (AVCi) agudo tratados com terapia trombolítica intravenosa (TTI), baseado em variáveis simples presentes à admissão. Métodos Análise retrospectiva de casos de AVCi tratados com TTI em um hospital no Rio de Janeiro. Variáveis clín icas e radiográficas foram selecionadas para análise. Foi utilizada regr...
Source: Arquivos de Neuro-Psiquiatria - December 15, 2016 Category: Neurology Source Type: research

Single Gene Causes of Stroke
Semin Neurol 2017; 37: 351-365 DOI: 10.1055/s-0037-1603952Though rare, monogenic causes of stroke are recognizable by key clinical and radiographic features. A lack of epidemiological data leaves their true incidence unknown, but the most common monogenetic causes of stroke are sickle cell disease, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), Fabry's disease, and cerebral cavernous malformations. In this article, the author covers the epidemiology, clinical features, and treatment of those diseases as well as other well-described monogenic causes of ischemic and hemo...
Source: Seminars in Neurology - July 31, 2017 Category: Neurology Authors: Majersik, Jennifer Juhl Tags: Review Article Source Type: research

Outcomes in Patients With Acute Stroke Requiring Mechanical Ventilation: Predictors of Mortality and Successful Extubation.
CONCLUSIONS: The in-hospital mortality rate of patients with acute stroke who require mechanical ventilation is quite high. The success rate with planned extubation is relatively good and comparable to rates in previous studies which largely involved patients with respiratory failure. There is no single weaning parameter or Glasgow coma scale score which identifies patients with high success rates. PMID: 30049327 [PubMed - in process]
Source: The American Journal of the Medical Sciences - July 1, 2018 Category: General Medicine Authors: Popat C, Ruthirago D, Shehabeldin M, Yang S, Nugent K Tags: Am J Med Sci Source Type: research

Evaluating the use of gradient echo imaging for the detection of cerebral microbleeds in acute stroke cases: A retrospective data analysis in a UK stroke unit
Imaging in stroke, allows its classification into ischaemic stroke (IS) or intracranial haemorrhagic stroke (ICH), ensuring time-sensitive treatment to be administered. Imaging can also allow detection of cerebral microbleeds (CMBs), which may further determine pharmacological intervention in acute stroke. True gradient echo (T2 ∗GRE) or susceptibility weighted imaging (SWI) have high sensitivity for the detection of CMBs. These two sequences are included in the national guidelines; however, the implementation of these guidelines can vary depending on local interpretation and scanner capabilities.
Source: Radiography - December 3, 2020 Category: Radiology Authors: G. Walsh, T. Meagher, C. Malamateniou Source Type: research

Factors associated with stroke formation in blunt cerebrovascular injury: An EAST multicenter study
BACKGROUND Stroke risk factors after blunt cerebrovascular injury (BCVI) are ill-defined. We hypothesized that factors associated with stroke for BCVI would include medical therapy (i.e., Aspirin), radiographic features, and protocolization of care. METHODS An Eastern Association for the Surgery of Trauma–sponsored, 16-center, prospective, observational trial was undertaken. Stroke risk factors were analyzed individually for vertebral artery (VA) and internal carotid artery (ICA) BCVI. Blunt cerebrovascular injuries were graded on the standard 1 to 5 scale. Data were from the initial hospitalization only. R...
Source: The Journal of Trauma: Injury, Infection, and Critical Care - February 1, 2022 Category: Orthopaedics Tags: 2021 EAST PODIUM PAPERS Source Type: research

E-096 COVID status is related to clot burden during thrombectomy in acute stroke patients
ConclusionOf 230 patients included in this interim analysis across 24 centers in the United States, between 02/2021 and 01/2022, 16 patients had a history of COVID. Comparing COVID-positive to non-positive, patients with COVID were younger (median 66.5 years vs 71.5 years, p 0.042), and had more intracranial clot by weight (median 101.0 mg vs 42.0 mg, p 0.047). There was a trend toward COVID positive patients to have more clot volume (median 180 cc vs 77.5 cc p 0.08), suggesting the difference was a higher clot burden instead of more density to the thrombus. These results suggest different histopathological characteristics...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Dabney, A., Vicari, J., Rivet, D., Woodward, B., Nanda, A., Fiorella, D., Baltan, S., Sohrabji, F., Pennypacker, K., Kellner, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Prevalence and Determinants of White Matter Hyperintensities in Young Stroke Patients (P03.160)
CONCLUSIONS: Our preliminary data suggest a high prevalence of WMHs in a young stroke population. We observed significant associations between mod-severe WMHs and hypertension, renal dysfunction, CMB burden, and cortical atrophy. Characterization of WMHs in young populations with specific stroke subtypes warrants further investigation.Disclosure: Dr. Catanese has nothing to disclose. Dr. Shoamanesh has nothing to disclose. Dr. Rayhill has nothing to disclose. Dr. Lau has nothing to disclose. Dr. Romero has nothing to disclose. Dr. Babikian has nothing to disclose. Dr. Benavente has received personal compensation for activi...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Catanese, L., Shoamanesh, A., Rayhill, M., Lau, H., Romero, J., Babikian, V., Benavente, O., Kase, C., Pikula, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Transcranial Laser Therapy and Infarct Volume Brief Reports
Conclusions— TLT was not associated with a reduction in overall or cortical infarct volume as measured on computed tomography in the subacute phase.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Kasner, S. E., Rose, D. Z., Skokan, A., Walker, M. G., Shi, J., Streeter, J., the NEST-2 Steering Committee and Investigators Tags: Acute Cerebral Infarction, Neuroprotectors Brief Reports Source Type: research