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Total 585 results found since Jan 2013.

Emerging Risk Factors for Recurrent Vascular Events in Patients With Embolic Stroke of Undetermined Source Clinical Sciences
Conclusions—History of diabetes mellitus and the CAM score could be novel risk factors for recurrent vascular events in embolic stroke of undetermined source.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Ueno, Y., Yamashiro, K., Tanaka, R., Kuroki, T., Hira, K., Kurita, N., Urabe, T., Hattori, N. Tags: Echocardiography, Embolism Original Contributions Source Type: research

Timing of symptomatic intracerebral hemorrhage after rt-PA treatment in ischemic stroke
Conclusions Our findings suggest that rt-PA patients have the highest risk of post rt-PA sICH within the first 24 hours after treatment. This supports monitoring of rt-PA-treated patients in specialized settings such as neuro-intensive care units or stroke units. Our findings suggest that the probability of sICH is low 36 hours post rt-PA. Future larger studies are warranted to identify the patterns of bleeding after rt-PA administration.
Source: Neurology Clinical Practice - August 11, 2019 Category: Neurology Authors: Chen, P. M., Lehmann, B., Meyer, B. C., Rapp, K., Hemmen, T., Modir, R., Agrawal, K., Hailey, L., Mortin, M., Meyer, D. M. Tags: All Cerebrovascular disease/Stroke, Intracerebral hemorrhage Research Source Type: research

Intravenous Thrombolysis Onset To Treatment Time Has A Small Effect On In-Hospital Outcomes In Acute Ischemic Stroke (P7.127)
Conclusion: The impact of OTT time on clinical and radiographic in-hospital outcomes was not detectable with prolonged experience at a single center.Disclosure: Dr. Malhotra has nothing to disclose. Dr. Ramanathan has nothing to disclose. Dr. Hackett has nothing to disclose. Dr. Quigley has nothing to disclose. Dr. Tian has nothing to disclose. Dr. Protetch has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Wright has nothing to disclose. Dr. Tayal has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Malhotra, K., Ramanathan, S., Hackett, C., Quigley, M., Tian, M., Protetch, J., Wong, C., Wright, D., Tayal, A. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

White Matter Integrity and Early Outcomes After Acute Ischemic Stroke
AbstractChronic white matter structural injury is a risk factor for poor long-term outcomes after acute ischemic stroke (AIS). However, it is unclear how white matter structural injury predisposes to poor outcomes after AIS. To explore this question, in 42 AIS patients with moderate to severe white matter hyperintensity (WMH) burden, we characterized WMH and normal-appearing white matter (NAWM) diffusivity anisotropy metrics in the hemisphere contralateral to acute ischemia in relation to ischemic tissue and early functional outcomes. All patients underwent brain MRI with dynamic susceptibility contrast perfusion and diffu...
Source: Translational Stroke Research - January 28, 2019 Category: Neurology Source Type: research

Three Territory Sign: An MRI marker of malignancy-related ischemic stroke (Trousseau syndrome)
Conclusion The TTS is a highly specific marker and 6 times more frequently observed in malignancy-related ischemic stroke than atrial fibrillation-related ischemic stroke. Evaluation for underlying malignancy in patients with the TTS is reasonable in patients with undetermined etiology.
Source: Neurology Clinical Practice - April 7, 2019 Category: Neurology Authors: Nouh, A. M., Staff, I., Finelli, P. F. Tags: MRI, DWI, All Cerebrovascular disease/Stroke, All Oncology Research Source Type: research

Outcomes after endovascular treatment for anterior circulation stroke presenting as wake-up strokes are not different than those with witnessed onset beyond 8 hours
Conclusions Rates of good outcomes, parenchymal hematoma, and final infarct volumes following endovascular treatment may not be different in patients with WUS compared with patients with witnessed onset of symptoms beyond 8 h.
Source: Journal of NeuroInterventional Surgery - November 13, 2015 Category: Neurosurgery Authors: Aghaebrahim, A., Leiva-Salinas, C., Jadhav, A. P., Jankowitz, B., Zaidi, S., Jumaa, M., Urra, X., Amorim, E., Zhu, G., Giurgiutiu, D.-V., Horev, A., Reddy, V., Hammer, M., Wechsler, L., Wintermark, M., Jovin, T. Tags: Ischemic stroke Source Type: research

Collateral flow as causative of good outcomes in endovascular stroke therapy
Conclusions Improved collateral flow in patients with AIS undergoing endovascular therapy was associated with improved radiographic and clinical outcomes. Independent of age, vessel occlusion and time, in patients with comparable ischemic burdens, changes in collateral grade alone led to significant differences in initial stroke severity as well as ultimate clinical outcome.
Source: Journal of NeuroInterventional Surgery - December 13, 2015 Category: Neurosurgery Authors: Sheth, S. A., Sanossian, N., Hao, Q., Starkman, S., Ali, L. K., Kim, D., Gonzalez, N. R., Tateshima, S., Jahan, R., Duckwiler, G. R., Saver, J. L., Vinuela, F., Liebeskind, D. S., for the UCLA Collateral Investigators Tags: Ischemic stroke Source Type: research

Clinical and Procedural Predictors of Outcomes From the Endovascular Treatment of Posterior Circulation Strokes Clinical Sciences
Conclusions— Time to the start of the procedure is an important predictor of clinical success after thrombectomy in patients with posterior circulation strokes. Both stent retriever and aspiration thrombectomy as primary treatment approaches are effective in achieving successful recanalization.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Mokin, M., Sonig, A., Sivakanthan, S., Ren, Z., Elijovich, L., Arthur, A., Goyal, N., Kan, P., Duckworth, E., Veznedaroglu, E., Binning, M. J., Liebman, K. M., Rao, V., Turner, R. D., Turk, A. S., Baxter, B. W., Dabus, G., Linfante, I., Snyder, K. V., Lev Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Clinical Sciences Source Type: research

Rapidly improving neurological deficit of stroke; case series in Academic institute, KAUH, Jeddah (P4.283)
Conclusions:Rapidly improving patient represent a challenge to whether tPA should be given. However, the good outcome with thrombolytic therapy observed in our study, will hopfuly support the decision to treat.Study Supported by: nonDisclosure: Dr. khoja has nothing to disclose. Dr. Alshaer has nothing to disclose. Dr. al-Turkistani has nothing to disclose. Dr. Al-Mekhalfi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: khoja, a., Al-Shaer, D., al-Turkistani, a., Al-Mekhalfi, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Letter to Editor on “Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features”
We read with much pleasure the article “Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features” by Vela et al published in the Journal of Stroke and Cerebrovascular Disease.1 Authors have done a commendable job at describing the clinical and radiographical details of stroke in a cohort of patients with cryptoco ccal meningitis. Authors have collected extensive data over 18years from the University of Colorado Hospital, and have identified 42 patients. Among these, 32 (76%) of the patients had available neuroimaging.
Source: Journal of Stroke and Cerebrovascular Diseases - March 14, 2019 Category: Neurology Authors: Ajay K. Mishra, Anu A. George, Kamal K. Sahu, Amos Lal, Cijoy K. Kuriakose Tags: Letter to the Editor Source Type: research

Cerebral Herniation Secondary to Stroke-associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Stephan A. Mayer, Justin Santarelli, Chirag Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

Operator assessment versus core laboratory adjudication of recanalization following endovascular treatment of acute ischemic stroke: a systematic review and meta-analysis
Conclusion Operator angiographic reads are statistically significantly higher than core laboratory-read readings following stroke thrombectomy, especially for complete recanalization. These differences should be considered when interpreting reports of angiographic outcomes after thrombectomy.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Ibrahim, M. K., Shehata, M. A., Ghozy, S., Bilgin, C., Jabal, M. S., Heiferman, D. M., Kadirvel, R., Kallmes, D. F. Tags: Ischemic stroke Source Type: research

White Matter Hyperintensity Volume Correlates with Matrix Metalloproteinase-2 in Acute Ischemic Stroke
Background: White matter hyperintensity (WMH), a common radiographic finding associated with stroke risk and outcome, has been linked to matrix metalloproteinase (MMP) activity and increased levels of oxidative stress in nonstroke populations. We sought to determine whether WMH severity is associated with plasma levels of MMPs and oxidative stress (F2-isoprostane) in subjects with acute ischemic stroke (AIS).Methods: We measured plasma biomarker levels at baseline and 48 hours in consecutive AIS subjects. White matter hyperintensity volume (WMHv) was quantified on admission magnetic resonance imaging using a validated sem...
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2014 Category: Neurology Authors: Zachary A. Corbin, Natalia S. Rost, Svetlana Lorenzano, Walter N. Kernan, Michael K. Parides, Jeffrey B. Blumberg, Paul E. Milbury, Ken Arai, Sophia N. Hartdegen, Eng H. Lo, Steven K. Feske, Karen L. Furie Tags: Original Articles Source Type: research

Intravenous Versus Intra-arterial Thrombolysis for Anterior Circulation Stroke Secondary to Large Vessel Occlusion
This study compared the radiographic and clinical outcomes of 51 patients who underwent intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rtPA) with 46 patients who underwent intra-arterial thrombolysis (IAT) with Penumbra System clot aspiration device (Penumbra, Alameda, CA) with or without the Solitaire stentriever device (ev3, Irvine, CA).
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2015 Category: Neurology Authors: Dale Ding Tags: Letter to the Editor Source Type: research