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Total 585 results found since Jan 2013.

A Direct Aspiration First Pass Technique (ADAPT) for acute stroke therapy: a systematic review and meta ‐analysis
ConclusionsADAPT therapy is associated with similar reperfusion rates, clinical outcomes, and complication rates compared to thrombectomy with stent retrievers. However, major limitations of current evidence (ie, retrospective studies and selection bias) indicate a need for adequately powered, multicenter randomized controlled trials to determine the best strategy.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - October 20, 2017 Category: Neurology Authors: Benjamin Gory, Xavier Armoiry, Rotem Sivan ‐Hoffman, Michel Piotin, Mikael Mazighi, Bertrand Lapergue, Raphaël Blanc, Francis Turjman Tags: Original Article Source Type: research

Presence of the hyperintense acute reperfusion marker on MRI after mechanical thrombectomy for large vessel occlusion is associated with worse early neurological recovery
Conclusions This preliminary analysis shows that the presence of HARM may be linked to worse neurological recovery 24 hours after thrombectomy. Reperfusion injury may affect the number of patients achieving functional independence after treatment.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Gupta, R., Sun, C.-H. J., Rochestie, D., Owada, K., Khaldi, A., Johnson, A. K., Horn, C. M. Tags: Ischemic stroke Source Type: research

Cerebral Autoregulation in Stroke
AbstractPurpose of ReviewCerebral autoregulation (CA) is a mechanism that maintains cerebral blood flow constant despite fluctuations in systemic arterial blood pressure. This review will focus on recent studies that measured CA non-invasively in acute cerebrovascular events, a feature unique to the transcranial Doppler ultrasound. We will summarize the rationale for CA assessment in acute cerebrovascular disorders and specifically evaluate the existing data on the value of CA measures in relation to clinical severity, guiding management decisions, and prognostication.Recent FindingsExisting data suggest that CA is general...
Source: Current Atherosclerosis Reports - May 21, 2018 Category: Cardiology Source Type: research

The imperative need to identify stroke risk stratification models for patients with asymptomatic carotid artery stenosis
The optimal management of patients with asymptomatic carotid stenosis (ACS) is controversial. The study by Klarin et  al1 provides important novel information that challenges the theory claiming that medical treatment (MT) alone is adequate for the management of all patients with ACS and that prophylactic carotid endarterectomy is not justified in any of these patients.2 Klarin et al1 showed that 112 of 219 pat ients (50%) with radiographically confirmed first-ever carotid-related strokes did actually receive antiplatelet therapy before their stroke, and 121 of 219 patients (55%) received lipid-lowering therapy (most ...
Source: Journal of Vascular Surgery - September 20, 2018 Category: Surgery Authors: Kosmas I. Paraskevas, Jean-Baptiste Ricco Tags: Letter to the Editor Source Type: research

Cerebral Autoregulation in Stroke
AbstractPurpose of ReviewCerebral autoregulation (CA) is a mechanism that maintains cerebral blood flow constant despite fluctuations in systemic arterial blood pressure. This review will focus on recent studies that measured CA non-invasively in acute cerebrovascular events, a feature unique to the transcranial Doppler ultrasound. We will summarize the rationale for CA assessment in acute cerebrovascular disorders and specifically evaluate the existing data on the value of CA measures in relation to clinical severity, guiding management decisions, and prognostication.Recent FindingsExisting data suggest that CA is general...
Source: Current Atherosclerosis Reports - May 21, 2018 Category: Cardiology Source Type: research

A Non-linear Association Between Total Small Vessel Disease Score and Hemorrhagic Transformation After Ischemic Stroke With Atrial Fibrillation and/or Rheumatic Heart Disease
Background: Previous studies have investigated the association between a single marker of cerebral small vessel disease (SVD) and hemorrhagic transformation (HT). However, the effect of the total SVD burden on HT has not been evaluated yet. We aimed to investigate the association between the total SVD score and HT in ischemic stroke patients with atrial fibrillation (AF) and/or rheumatic heart disease (RHD). Methods: Ischemic stroke patients with AF and/or RHD admitted within 7 days after onset were enrolled at two hospitals in China. The total SVD score was based on the presence of lacunes, extensive white matter hyperin...
Source: Frontiers in Neurology - July 23, 2019 Category: Neurology Source Type: research

Distribution of ischemic strokes in patients with atrial fibrillation: The FibStroke Study
Conclusions The timing of AF diagnosis, use of OAC drugs, or the CHA2DS2-VASc score did not affect the distribution of ischemic strokes. Anterior territory strokes were slightly more often located within the left hemisphere.
Source: Neurology Clinical Practice - August 11, 2019 Category: Neurology Authors: Jaakkola, J., Hartikainen, P., Kiviniemi, T. O., Nuotio, I., Palomäki, A., Hartikainen, J. E. K., Ylitalo, A., Mustonen, P., Airaksinen, K. E. J. Tags: All Cerebrovascular disease/Stroke, Cardiac, Embolism, Infarction Research Source Type: research

Simultaneous revascularization of the occluded internal carotid artery using the Solitaire as a workhorse wire during acute ischemic stroke intervention.
CONCLUSION: As the management paradigms of tandem occlusions continue to evolve, this technique may improve outcomes by expediting endovascular intervention. Using the stent retriever wire provides a method of expediting the management of the proximal lesion after addressing the more distal intracranial occlusion first. PMID: 31696768 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - November 9, 2019 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Role of Radiological Eye Deviation in Imaging Occult Cases of Acute Large Vessel Occlusion
The recent article from McCluskey et al “Radiological Eye Deviation as a Predictor of Large Vessel Occlusion in Acute Ischaemic Stroke” J of Stroke and Cerebrovasc Dis. 2019; 28:2318-23231 provides valuable information that may lead to early stroke intervention. They found that subjective visual detection of radiographic eye deviation on nonenhanced computed tomography (NECT) brain is strongly associated with large vessel occlusion (LVO). This compelling association may expedite patients for timely angiographic testing and endovascular therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2020 Category: Neurology Authors: Nan N. Jiang, Wei Wu, Crystal Fong, Demetrios J. Sahlas, Ramiro Larrazabal Tags: Letter to the Editor Source Type: research

High Monocyte-To-Lymphocyte Ratio Is Associated With Stroke-Associated Pneumonia
Conclusions: Our study showed that higher MLR was significantly associated with SAP in AIS patients. MLR is beneficial for clinicians to recognize patients with a high risk of SAP at an early stage and is an effective way to improve clinical care of SAP patients. Higher MLR could be a helpful and valid biomarker for predicting SAP in clinical practice.
Source: Frontiers in Neurology - October 5, 2020 Category: Neurology Source Type: research

Work satisfaction among neuroradiology staff after receiving follow up reports of thrombectomy stroke patients
by Charlotte Hager, Homan Taufik, Friederike Blum, Andrea Stockero, Martin Wiesmann, Arno Reich, Rebecca May, Omid Nikoubashman Background and purposeDuring a period of 6 months, we provided our entire neuroradiological staff including physicians, radiographers, and researchers with systematic feedback via email on the further clinical course of stroke patients who underwent mechanical thrombectomy. We analyzed the effects of this feedback on work satisfaction, work meaningfulness and valuation of the therapy among our staff. MethodsOur staff completed two self-reported questionnaires before and after the period of six mon...
Source: PLoS One - May 19, 2021 Category: Biomedical Science Authors: Charlotte Hager Source Type: research

Telemedicine remote controlled stroke evaluation and treatment, the experience of radiographers, paramedics and junior doctors in a novel rural stroke management team
In the case of ischemic stroke, access to a Computed Tomography (CT) scanner and the start of thrombolytic therapy immediately is imperative. Transport to the nearest hospital from the remote, rural area of Ha...
Source: BMC Health Services Research - June 5, 2021 Category: General Medicine Authors: Elin Kjelle and Aud Mette Myklebust Tags: Research Source Type: research

Stroke Following Thoracic Endovascular Aortic Repair: Determinants, Short and Long Term Impact
We performed a contemporary assessment of clinical and radiographic factors of stroke after thoracic endovascular aortic repair (TEVAR). Patients undergoing TEVAR from 2006-2017 were identified. We assessed clinical and radiographic data, including preoperative head and neck computed tomography, Doppler ultrasonography and intraoperative angiography. Our primary outcome was stroke after TEVAR. 479 patients underwent TEVAR, mean age 68.1 ±19.5 years, 52.6% male. Indications for TEVAR included aneurysms (n=238, 49.7%) or dissections (n=152, 31.7%).
Source: Seminars in Thoracic and Cardiovascular Surgery - January 25, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Arnoud V. Kamman, Pieter A.J. van Bakel, Bo Yang, David M. Williams, Karen M. Kim, Minhaj S. Khaja, Frans L. Moll, Joost A. van Herwaarden, Santi Trimarchi, Kim A. Eagle, Jonathan L. Eliason, Himanshu J. Patel Tags: ADULT – Original Submission Source Type: research

Natural Language Processing of Radiology Reports to Detect Complications of Ischemic Stroke
ConclusionsOur study demonstrates robust performance and external validity of a core NLP tool kit for identifying both categorical and continuous outcomes of ischemic stroke from unstructured radiographic text data. Medically tailored NLP methods have multiple important big data applications, including scalable electronic phenotyping, augmentation of clinical risk prediction models, and facilitation of automatic alert systems in the hospital setting.
Source: Neurocritical Care - May 9, 2022 Category: Neurology Source Type: research

BOBBY balloon guide catheter thrombectomy in large-vessel occlusion stroke: Initial experience
CONCLUSIONS: BOBBY BGC use resulted in a high first-pass effect rate and may contribute towards improved functional outcomes.PMID:35645160 | DOI:10.1177/15910199221104920
Source: Interventional Neuroradiology - June 1, 2022 Category: Radiology Authors: Karan Topiwala Coridon Quinn Tapan Mehta Kamran Masood Andrew Grande Ramachandra Tummala Bharathi Jagadeesan Source Type: research