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Total 585 results found since Jan 2013.

Hemothorax after the intravenous administration of tissue plasminogen activator in a patient with acute ischemic stroke and rib fractures.
Abstract A 79-year-old man experienced sudden-onset left hemiparesis and disturbance of consciousness. Diffusion-weighted magnetic resonance imaging showed an acute ischemic stroke in the territory of the right middle cerebral artery. He underwent systemic thrombolysis via the intravenous administration of tissue plasminogen activator (t-PA). Chest radiography and computed tomography performed the following day showed severe hemothorax with atelectasis of the left lung and multiple rib fractures; the initial chest radiogram had revealed rib fractures but we did not recognize them at the time. Conservative treatmen...
Source: Journal of Nippon Medical School - March 15, 2014 Category: Universities & Medical Training Authors: Shirokane K, Umeoka K, Mishina M, Mizunari T, Kobayashi S, Teramoto A Tags: J Nippon Med Sch Source Type: research

Left Ventricular Hypertrophy as a Predictor of White Matter Hyperintensities in Young Stroke Patients (P2.111)
CONCLUSIONS: A large proportion of WMH in our cohort is hypertensive. Our preliminary data suggest that LVH may aid in determining the pathophysiology underlying WMH in young adults with stroke, independent from HTN. Further analyses are needed to confirm our findings.Study Supported by: NoneDisclosure: Dr. Catanese has nothing to disclose. Dr. Shoamanesh has nothing to disclose. Dr. Lau has nothing to disclose. Dr. Romero has nothing to disclose. Dr. Babikian has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Pikula has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Catanese, L., Shoamanesh, A., Lau, H., Romero, J., Babikian, V., Kase, C., Pikula, A. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

The Influence Of Obesity On Outcomes After Intravenous Thrombolysis For Acute Ischemic Stroke (P5.007)
Conclusion: Obese patients receiving IV t-PA treatment for acute ischemic stroke had similar rates of in-hospital mortality, discharge to home and sICH, but they had longer LOS and rates of UTI. Future studies should be undertaken to determine if the clinical efficacy of tPA is affected by under-dosing focusing on both radiographic recanalization rates and functional clinical outcomes.Disclosure: Dr. Nickles has nothing to disclose. Dr. Chaudry has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Reeves has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Nickles, A., Chaudry, S., Hussain, S., Reeves, M. J. Tags: Cerebrovascular Disease and Interventional Neurology II Source Type: research

Iatrogenesis imperfecta: stroke caused by accidental carotid artery catheterization.
CONCLUSION:: Even with ultrasound-guided central venous catheterization, it is essential to remain vigilant for the early detection of vascular complications. Clinical suspicion combined with diagnostic modalities such as chest radiograph, transduction and manometry can increase the detection rates. PMID: 25041919 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - November 27, 2014 Category: Surgery Tags: J Vasc Access Source Type: research

Enterobacter Cloacae Endocarditis Presenting as an Ischemic Stroke (P2.279)
CONCLUSIONS: This is the first case which demonstrates that ischemic stroke can be the presenting clinical event of E. cloacae endocarditis. Clinicians who provide acute care to patients with stroke should be aware of this rare cause of embolic brain infarction. Our case shows that early diagnosis of E. cloacae endocarditis and appropriate medical management can promote full neurological recovery in these patients. Disclosure: Dr. mannel has nothing to disclose. Dr. Silliman has received personal compensation for activities with Biogen Idec, and Teva Neuroscience as a consultant and/or speaker. Dr. Silliman has received re...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mannel, R., Silliman, S. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Emergent extracranial internal carotid artery stenting and mechanical thrombectomy in acute ischaemic stroke.
CONCLUSIONS: Treatment of tandem extracranial ICA and intracranial occlusions in the setting of acute ischaemic stroke with extracranial carotid artery stenting followed by adjunctive intracranial mechanical thrombectomy is both safe and effective, but further evaluation of this treatment modality is necessary. PMID: 25943850 [PubMed - in process]
Source: Interventional Neuroradiology - June 3, 2015 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Factors correlating with reperfusion injury after endovascular therapy and tissue plasminogen activator for acute ischemic stroke (P5.268)
Conclusions:While our results are limited by the small sample size, we found that reperfusion injury was most common in patients receiving combination therapy. Large stroke measured by infarct volume correlated with higher likelihood of hemorrhage.Disclosure: Dr. Soomro has nothing to disclose. Dr. Zelnick has nothing to disclose. Dr. Sarraj has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Soomro, J., Zelnick, P., Sarraj, A. Tags: Acute Cerebrovascular Interventional Therapies Source Type: research

Association of clot burden score with radiographic and clinical outcomes following Solitaire stent retriever thrombectomy: analysis of the SWIFT PRIME trial
Conclusions The combination of IV thrombolysis and stent retriever thrombectomy with the Solitaire device is highly effective in achieving successful recanalization and a good clinical outcome throughout the entire range of CBS values.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Mokin, M., Levy, E. I., Siddiqui, A. H., Goyal, M., Nogueira, R. G., Yavagal, D. R., M Pereira, V., Saver, J. L. Tags: Ischemic stroke Source Type: research

Radiographic and symptomatic brain ischemia in CEA and CAS: A systematic review and meta-analysis
Conclusions: One in 5 persons with periprocedural radiographic brain ischemia during CEA and CAS had strokes and TIAs. The stable ratio of stroke and TIA to radiographic ischemia suggests that MRI ischemia could serve as a surrogate measure of periprocedural risk.
Source: Neurology - November 6, 2017 Category: Neurology Authors: Cho, S.-M., Deshpande, A., Pasupuleti, V., Hernandez, A. V., Uchino, K. Tags: MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Mechanical thrombectomy in basilar artery occlusion: influence of reperfusion on clinical outcome and impact of the first-line strategy (ADAPT vs stent retriever).
CONCLUSIONS Among BAO patients, successful reperfusion is a strong predictor of a 90-day favorable outcome, and the choice of ADAPT as the first-line strategy achieves a significantly higher rate of complete reperfusion with a shorter procedure duration. PMID: 29327997 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 12, 2018 Category: Neurosurgery Authors: Gory B, Mazighi M, Blanc R, Labreuche J, Piotin M, Turjman F, Lapergue B, Endovascular Treatment in Ischemic Stroke (ETIS) Research Investigators Tags: J Neurosurg Source Type: research

Cerebral Hyperperfusion Syndrome After Carotid Revascularization and Acute Ischemic Stroke
AbstractPurpose of ReviewCerebral hyperperfusion syndrome (CHS) is a rare but significant complication after carotid revascularization and is increasingly recognized after acute stroke treatments. In this review, we discuss the epidemiology and pathophysiology of CHS, clinical presentation including ipsilateral headache, seizures, and focal neurological deficits, and radiographic presentation. We propose preventive therapies with emphasis on acute stroke post-thrombectomy hyperperfusion.Recent FindingsCHS was first described after carotid revascularization but is now also reported in patients with acute ischemic stroke. Pr...
Source: Current Pain and Headache Reports - March 19, 2018 Category: Neurology Source Type: research

Endovascular Thrombectomy for Acute Ischemic Stroke
AbstractPurpose of ReviewTo review the current evidence supporting the use of endovascular thrombectomy (EVT) for the treatment of acute ischemic stroke (AIS) due to anterior circulation large vessel occlusion (LVO).Recent FindingsRecent advances in AIS management by EVT have led to significant reduction in morbidity and mortality in selected patients with LVO within the anterior circulation. Until recently, use of EVT was strictly based on time criteria, within 4.5 to 12  h of symptom onset with many patients presenting with “wake-up” stroke who were not considered for EVT. The positive results of the DAWN and DEFUSE...
Source: Current Cardiology Reports - August 29, 2019 Category: Cardiology Source Type: research

Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke patients with prohibitive vascular access.
CONCLUSIONS: DCP for emergency MT in patients with anterior circulation AIS-LVO and prohibitive vascular access is safe and effective and is associated with higher recanalization rates, smaller infarct volumes, and improved functional outcome compared with patients with abMT after failed transfemoral access. DCP should be considered in this patient population. PMID: 32796146 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - August 13, 2020 Category: Neurosurgery Authors: Cord BJ, Kodali S, Strander S, Silverman A, Wang A, Chouairi F, Koo AB, Nguyen CK, Peshwe K, Kimmel A, Porto CM, Hebert RM, Falcone GJ, Sheth KN, Sansing LH, Schindler JL, Matouk CC, Petersen NH Tags: J Neurosurg Source Type: research

Risk Estimation of Infectious and Inflammatory Disorders in Hospitalized Patients With Acute Ischemic Stroke Using Clinical-Lab Nomogram
Conclusions: The clinical-lab nomogram predicted IAID in patients with acute ischemic stroke. As a result, this nomogram can be used for identification of high-risk patients and to further guide clinical decisions.
Source: Frontiers in Neurology - December 10, 2021 Category: Neurology Source Type: research

LB-005 The INSIGHT registry: a multi-center, multi-omic stroke clot study, preliminary results
ConclusionThese preliminary results demonstrate the real-world applicability of the INSIGHT study to typical stroke thrombectomy population. Furthermore, the tissue processing protocols are providing high-quality RNA and protein for analysis, which is currently underway.DisclosuresJ. Fraser: 1; C; Penumbra, University of Kentucky. 2; C; Stream Biomedical, Medtronic. 4; C; Cerelux, Fawkes Biotechnology. J. Vicari: None. A. Nanda: None. E. Cheng-Ching: None. K. Woodward: None. B. Rapoport: None. C. Kellner: None.
Source: Journal of NeuroInterventional Surgery - July 29, 2021 Category: Neurosurgery Authors: Fraser, J., Vicari, J., Nanda, A., Cheng-Ching, E., Woodward, K., Rapoport, B., Kellner, C. Tags: Late-breaking oral abstracts Source Type: research