Facial palsy as a neurological complication of SARS-CoV-2
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledg...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Possible acute multifocal demyelinating lesions in a COVID-19 patient
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledg...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Pontine hot cross bun sign in spinocerebellar ataxia type 2
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledg...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledg...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Heracles and epilepsy: the sacred disease
ABSTRACT Epilepsy is one of the most dreaded and terrifying human afflictions. One of the many names it has received was Sacred Disease, during Greek times. Heracles served as a source of the divine connotation that epilepsy received in ancient times, as he was one of the most important demigods in Greek mythology. However, several authors have attributed Heracles ’ actions to a seizure, including Hippocrates, who described the sacred disease on his “ Corpus Hippocraticum. ” This paper reviewed some of the publications on the myth and content of the text of Hippocrates, in relation to the current knowledg...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Intracerebral hemorrhage: update and future directions
ABSTRACT Intracerebral hemorrhage (ICH), defined as bleeding into the brain parenchyma, is a significant public health issue. Although it accounts for only 10 to 15% of strokes, it is associated with the highest morbidity and mortality rates. Despite advances in the field of stroke and neurocritical care, the principles of acute management have fundamentally remained the same over many years. The main treatment strategies include aggressive blood pressure control, early hemostasis, reversal of coagulopathies, clot evacuation through open surgical or minimally invasive surgical techniques, and the management of raised intra...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Current uses of intracranial vessel wall imaging for clinical practice: a high-resolution MR technique recently available
ABSTRACT Intracranial vessel wall imaging plays an increasing role in diagnosing intracranial vascular diseases. With the growing demand and subsequent increased use of this technique in clinical practice, radiologists and neurologists should be aware of the choices in imaging parameters and how they affect image quality, clinical indications, methods of assessment, and limitations in the interpretation of these images. Due to the improvement of the MRI techniques, the possibility of accurate and direct evaluation of the abnormalities in the arterial vascular wall (vessel wall imaging) has evolved, adding substantial data ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Dietary habits in a group of patients with multiple sclerosis are similar to those of healthy control subjects
Conclusion: The dietary patterns of patients with MS and healthy controls were similar in the city of Santos, S ão Paulo, Brazil, and surrounding towns, except for higher intake of carbohydrates by patients. No profile of pro-inflammatory diets was identified among the patients with MS enrolled in this study.RESUMO Introdu ção: Esclerose múltipla (EM) é uma doença crônica e autoimune do sistema nervoso central. Ao longo do tempo, pacientes com EM acumulam incapacidades neurológicas. A EM tipicamente afeta adultos jovens e se associa a um perfil inflamatório de c...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Validation of the Brazilian Portuguese version of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ-BR)
Conclusions: RBDSQ-BR is a reliable instrument, which may be useful for RBD diagnosis of Brazilian patients with PD. The instrument is also valid and may help in a better selection of cases for a more detailed clinical evaluation or even PSG analysis.RESUMO Introdu ção: O diagnóstico do transtorno comportamental do sono REM (TCSREM) implica na realização da polissonografia (PSG), mas sua disponibilidade pode não ser suficiente. Portanto, meios clínicos para o diagnóstico podem ser úteis. Objetivo: Validar para a língua portuguesa falada no Brasil o quest...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese
ABSTRACT Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops. To improve the recognition of this phenomenon, the 19-item wearing-off questionnaire (WOQ-19) was developed. Objective: To translate and validate the WOQ-19 into Portuguese. Methods: The questionnaire was translated into Portuguese and, subsequently, back-translated into English and analyzed. The final version was tested in Parkinson disease patients for reliability through the test-retest paradigm and internal consistency. Als...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Electroacupuncture alleviates inflammatory pain via adenosine suppression and its mediated substance P expression
Conclusion: Our results indicate regulation of adenosine-mediated substance P secretion. Substance P-mediated pathway may be involved in the analgesia process by electroacupuncture in rats.RESUMO Introdu ção: A acupuntura tem sido amplamente utilizada para alívio de dor. No entanto, seus mecanismos são muito pouco conhecidos. Objetivo: Investigar a relação entre o efeito analgésico da eletroacupuntura e a regulação da expressão de adenosina e de substância P. Métodos: Utilizou-se um modelo de dor inflamatória crônica em ratos po...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Analysis of YouTube as a source of information for restless leg syndrome
Conclusions: This study demonstrates that 77% of the videos uploaded on YouTube regarding RLS are in the useful category, whereas only 16 videos were providing misleading information. However, even videos in the useful category do not provide a full and complete description of the RLS.RESUMO Introdu ção: O YouTube é um dos principais recursos no mundo para vídeos relacionados à saúde. Objetivo: O objetivo deste estudo foi avaliar a qualidade das informações disponíveis no YouTube sobre a síndrome das pernas inquietas (SPI). Métodos: Realizou-se um...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Enriched environment alleviates post-stroke cognitive impairment through enhancing α7-nAChR expression in rats
Conclusions: EE markedly improves cognitive impairment and enhances neuroplasticity in PSCI rats, which may be closely related to enhancement of α 7-nAChR expression.RESUMO Introdu ção: O ambiente enriquecido (AE) é uma intervenção simples e eficaz para melhorar a função cognitiva no comprometimento cognitivo pós-AVC, em parte devido ao reequilíbrio da via de sinalização colinérgica no hipocampo. O receptor nicotínico α 7 de acetilcolina ( α 7-nAChR) é um receptor colinérgico cuja ativaçã...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

REM Behavior Disorder diagnostic challenges
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research

Erratum: Association between executive and food functions in the acute phase after stroke
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro rei...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Symptomatic female carriers of mutations in the Duchenne muscular dystrophy gene
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro rei...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Migrainous periorbital ecchymosis
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro rei...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

STIR and diffusion-weighted MRI in asymptomatic hyperCKemia caused by ANO5-related myopathy
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro rei...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

“…In the immortal forms of beauty”: Frédéric Chopin seen through the eyes of the father of Brazilian neurological semiology
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro rei...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Deep brain stimulation treatment in dystonia: a bibliometric analysis
Conclusions: DBS in dystonia research is mainly published in a handful of scientific journals and focused on the outcomes of the surgery in idiopathic or inherited, isolated, segmental or generalized dystonia, and with globus pallidus internus as the main DBS target.RESUMO Introdu ção: A distonia é uma doença heterogênea que, quando refratária ao tratamento medicamentoso, pode ter uma resposta favorável à estimulação encefálica profunda (EEP). Uma forma prática de ter uma visão desta área de pesquisa é por meio de an&aac...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Evidence and practices of the use of next generation sequencing in patients with undiagnosed autosomal dominant cerebellar ataxias: a review
ABSTRACT Autosomal dominant cerebellar ataxias (ADCA) are heterogeneous diseases with a highly variable phenotype and genotype. They can be divided into episodic ataxia and spinocerebellar ataxia (SCA); the latter is considered the prototype of the ADCA. Most of the ADCA are caused by polyglutamine expansions, mainly SCA 1, 2, 3, 6, 7, 17 and Dentatorubral-pallidoluysian atrophy (DRPLA). However, 30% of patients remain undiagnosed after testing for these most common SCA. Recently, several studies have demonstrated that the new generation of sequencing methods are useful for the diagnose of these patients. This review focus...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Neuropsychiatric changes during the COVID-19 pandemic in multiple sclerosis patients
Conclusions: The results provide a basis for the development of psychological interventions that could minimize the prevalence of sleep disorders and depression and could improve patients ’ quality of life during the outbreak.RESUMO Introdu ção: Este estudo relatou uma variedade de reações psicológicas relacionadas a ansiedade, qualidade do sono, depressão, fadiga e qualidade de vida em indivíduos com esclerose múltipla (EM), relacionadas à experiência de quarentena de COVID-19. Objetivo: O objetivo deste estudo foi invest igar os efeitos neuropsiqu...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Cutoff points in STOP-Bang questionnaire for obstructive sleep apnea
ABSTRACT Background: Obstructive Sleep Apnea Syndrome (OSAS) is a public health problem of high prevalence and impacts on quality of life, anesthetic complications and cardiovascular diseases. In view of the difficulty in accessing the polysomnography, it is necessary to validate other methods for OSAS diagnostic screening in clinical practice in our country, such as the STOP-Bang questionnaire. Objective: To validate the STOP-Bang questionnaire in Brazilians and evaluate optimal cutoff points. Methods: After translation and back-translation, STOP-Bang questionnaire was applied to 71 individuals previously submitted to pol...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Effects of Comorbid Fibromyalgia Syndrome on activities of daily living in multiple sclerosis patients
ABSTRACT Objective: To investigate the frequency of Comorbid Fibromyalgia Syndrome and its effects on quality of life and activities of daily living without any known psychiatric problem (schizophrenia or bipolar disorder) or severe disability, other than depression, in patients with multiple sclerosis, which is known to be a chronic disease in young adults. Methods: The study included 103 patients diagnosed with multiple sclerosis, following McDonald criteria, who had relapsing remitting disease. The Fibromyalgia Impact Questionnaire, Beck Anxiety Inventory, Beck Depression Inventory, Pittsburgh Sleep Quality Index, Fatig...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

The effect of cognitive task on postural stability in cervical dystonia
Conclusions: Postural control is impaired in CD patients probably due to the impaired proprioceptive and sensorimotor integration. In reference to dual task theories possibly due to divided attention and task prioritization, cognitive dual-task and harder postural task disturbes the PS in these patients.RESUMO Introdu ção: A distonia cervical (DC) é a forma mais comum de distonia focal. Não se sabe exatamente se posturas anormais da cabeça na DC causam problemas de equilíbrio. A execução de duas tarefas simultaneamente é situação comum da vida cot...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Can personality traits, obesity, depression, anxiety, and quality of life explain the association between migraine and disordered eating attitudes?
Conclusion: The association of migraine and disordered eating attitudes was shown to be related to depression, anxiety, quality of life and personality traits and may also indicate a more clinically severe migraine. To the best of our knowledge, there is no literature study that deals with all these relevant data together. However, neuropsychiatry-based biological studies are required to better understand this multifaceted association.RESUMO Introdu ção: Poucos estudos exploraram a coexistência de migrânea e hábitos alimentares inadequados. Além disso, os mecanismos fisiopatoló...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Endovascular technique simulator for Neuroradiology learning
Conclusion: The simulator is ready for testing by residents and can enable the student to learn through simulations that reproduce, as realistically as possible, the situation to be subsequently experienced using a concrete tool.RESUMO Introdu ção: O acidente vascular cerebral (AVC) é a terceira causa de morte em todo o mundo e uma oclusão arterial aguda é o principal mecanismo subjacente ao AVC isquêmico. As doenças cerebrovasculares são tratadas por intervenções endovasculares intracranianas utilizando técnicas intravascular es minimamente invasi...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

One more bite in the understanding of migraine psychiatric comorbidity: the role of eating attitudes
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Professor Emeritus Charles Peter Tilbery [1944-2020]
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Experimental neurocysticercosis and demyelination
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

The challenges of monitoring neurological manifestations associated with COVID-19 in Latin America: does the World Health Organization need changes?
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Panda with “bright eyes”: a rare sign in Wilson disease
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Convulsive syncope: a Stokes-Adams case
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

How can neurophysiological studies help with movement disorders characterization in clinical practice? A review
Conclusion: These studies can be helpful for the diagnosis and are usually underutilized in neurological practice.RESUMO Introdu ção: Os estudos neurofisiológicos são métodos auxiliares para compreender melhor as características e a natureza dos distúrbios do movimento. A eletromiografia (EMG), em associação com o eletroencefalograma (EEG) e o acelerômetro, podem ser utilizados para avaliar um espectro de movimento s hipo e hipercinéticos. Técnicas específicas podem ser aplicadas para melhor caracterizar a fenomenologia, ajudar a dist...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Resveratrol in Alzheimer's disease: a review of pathophysiology and therapeutic potential
Conclusion: Although resveratrol appears to mitigate some pathophysiological aspects of AD, further studies are needed to prove the safety and efficacy of this compound in humans.RESUMO Introdu ção: A doença de Alzheimer (DA) é neurodegenerativa e caracterizada por perda progressiva e irreversível da função cognitiva. A presença de placas senis é um dos marcadores patológicos da doença e está associada ao aparecimento de mecanismos neuroinflamatórios. A fisiopatologia exata d a DA ainda não é completamente compreendida,...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
Conclusions: Most neurological consultations in a COVID-19-dedicated hospital were requested for severe conditions that could have an impact on the outcome. First-line doctors should be able to recognize neurological symptoms; neu rologists are important members of the medical team in COVID-19 hospital care.RESUMO Introdu ção: Mais de um terço dos pacientes com COVID-19 apresentam sintomas neurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doenças neurológicas prévias podem exigir tratamento especial e estar associadas a piores desfechos. Não...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Health-related quality of life in patients with narcolepsy types 1 and 2 from a Sleep Center in Brazil
The objective of this study is to describe the quality of life in a sample of patients with narcolepsy, and the influence of the nutritional status in health domains. Methods: At Unifesp, two groups of 33 patients (narcolepsy types 1 and 2 meeting 2014 criteria, concerning hypocretin-1) and 33 controls without sleepiness, matched by age and sex, filled out the SF-36. Results: Narcolepsy groups, regardless of their nutritional status, had significantly lower scores in all domains, compared to controls, mainly in Role-physical, Role-emotional, and Energy/Fatigue. Role-physical score was lower in type 1 than in type 2 and con...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

The prognostic value of demyelinating electrophysiologic findings and cerebrospinal fluid protein levels in acute inflammatory demyelinating polyneuropathy
Conclusions: The number of demyelinating criteria that are met and high cerebrospinal fluid protein levels at the disease onset may be valuable prognostic markers. More systematic studies conducted with serial nerve conduction studies are required to highlight the roles of the suggested criteria in clinical practice.RESUMO Introdu ção: A síndrome de Guillain-Barré é uma polineuropatia imunomediada aguda caracterizada por sintomas e incapacidade em rápida evolução. A análise do líquido cefalorraquidiano e os estudos eletrofisiológicos são cr...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Fatigue in Parkinson’s disease: Brazilian validation of the modified fatigue impact scale
ABSTRACT Background: The instruments that measure the impact of fatigue on physical, cognitive and psychosocial aspects has yet to be validated in Brazilian population with Parkinson ’ s disease (PD). The aim of this study was to cross-culturally adapt and assess the psychometric properties of the Brazilian version of the Modified Fatigue Impact Scale (MFIS-PD/BR). Methods: Ninety PD individuals were recruited. The adaptation of the MFIS-PD was performed by translation and back translation methodology. Psychometric analysis was applied in order to perform the administration of the socio-clinical questionnaire, Mini-M...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Assessment of Work Productivity and Activity Impairment (WPAI) questionnaire for migraine with the help of a smartphone app
ABSTRACT Background: Migraine is a major cause of disability, which affects many areas of life, including productivity at work. Measuring absenteeism and presenteeism resulting from migraine with the use of appropriate tools is essential for better understanding the impact of this disease. Objective: The aim of the present study was to assess the work impact of migraine using the Brazilian Portuguese version of Work Productivity and Activity Impairment (WPAI) questionnaire. Methods: This survey was carried out with the aid of a smartphone app (Dr Cefaleia for Doctors) containing the questionnaires: ID-Migraine, Headache Im...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Effects of statin therapy on outcomes of ischemic stroke: a real-world experience in Brazil
Conclusions: Statins play an important role in the treatment of ischemic stroke, preventing stroke recurrence and cardiovascular events, and improving functional performance.RESUMO Introdu ção: A terapia com estatinas tornou-se um dos avanços mais importantes na prevenção secundária do acidente vascular cerebral (AVC). Objetivo: Fornecer evidências de dados do mundo real para avaliar associações detalhadas entre a prevenção secundária do AVC e o uso de estatinas no Bras il. Métodos: Realizamos um estudo de coorte prospectivo, incluind...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Neurological complications of COVID-19: from bridesmaid to bride
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Constipation associated to tension type of headache in women
ABSTRACT In this manuscript we pay a tribute to Pierre Marie (1853-1940), highlighting his great contribution to medicine and neurology describing several diseases and syndromes. We mainly emphasize aspects of his personal life and personality traits. Considered one of the three greatest neurologists of the late nineteenth and early twentieth centuries, his brilliant career began at La Salp êtrière, followed by the development of a neurological school at Hospice Bicêtre. Pierre Marie had numerous disciples around the world, including Brazil, and published on various neurological and endocrinological them...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Acute ischemic stroke in a patient with COVID-19
ABSTRACT In this manuscript we pay a tribute to Pierre Marie (1853-1940), highlighting his great contribution to medicine and neurology describing several diseases and syndromes. We mainly emphasize aspects of his personal life and personality traits. Considered one of the three greatest neurologists of the late nineteenth and early twentieth centuries, his brilliant career began at La Salp êtrière, followed by the development of a neurological school at Hospice Bicêtre. Pierre Marie had numerous disciples around the world, including Brazil, and published on various neurological and endocrinological them...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Three territory sign in cancer-related acute ischemic stroke
ABSTRACT In this manuscript we pay a tribute to Pierre Marie (1853-1940), highlighting his great contribution to medicine and neurology describing several diseases and syndromes. We mainly emphasize aspects of his personal life and personality traits. Considered one of the three greatest neurologists of the late nineteenth and early twentieth centuries, his brilliant career began at La Salp êtrière, followed by the development of a neurological school at Hospice Bicêtre. Pierre Marie had numerous disciples around the world, including Brazil, and published on various neurological and endocrinological them...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Who was Pierre Marie?
ABSTRACT In this manuscript we pay a tribute to Pierre Marie (1853-1940), highlighting his great contribution to medicine and neurology describing several diseases and syndromes. We mainly emphasize aspects of his personal life and personality traits. Considered one of the three greatest neurologists of the late nineteenth and early twentieth centuries, his brilliant career began at La Salp êtrière, followed by the development of a neurological school at Hospice Bicêtre. Pierre Marie had numerous disciples around the world, including Brazil, and published on various neurological and endocrinological them...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Management of acute stroke and urgent neurointerventional procedures during COVID-19 pandemic: recommendations on the Scientific Department on Cerebrovascular Diseases of the Brazilian Academy of Neurology, Brazilian Society of Cerebrovascular Diseases and Brazilian Society of Neuroradiology
ABSTRACT Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that with an inefficient treatment will further increase mortality and long-term disability. Objective: This paper summar...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Management of central nervous system demyelinating diseases during the coronavirus disease 2019 pandemic: a practical approach
Conclusions: In the future, real-world case series of MS/NMOSD patients infected with COVID-19 will help us define the best management strategies. For the time being, we rely on expert experience and guidance.RESUMO Introdu ção: A mais recente pandemia causada pelo coronavírus SARS-CoV-2 (COVID-19, do inglês coronavirus disease 2019) representa uma ameaça potencial para pacientes com doenças autoimunes, incluindo esclerose múltipla (EM) e transtorno do espectro de neuromielite óptica (NMOSD, do inglês neuromy elitis optica spectrum disorders). Esses pacientes s&a...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Evaluation of ubiquitin C-terminal hydrolase-L1 enzyme levels in patients with epilepsy
ABSTRACT Objective: Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) enzyme levels were investigated in patients with epilepsy, epileptic seizure, remission period, and healthy individuals. Methods: Three main groups were evaluated, including epileptic seizure, patients with epilepsy in the non-seizure period, and healthy volunteers. The patients having a seizure in the Emergency department or brought by a postictal confusion were included in the epileptic attack group. The patients having a seizure attack or presenting to the Neurology outpatient department for follow up were included in the non-seizure (remission period) group...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Validity and reliability of the 12-item Berg Balance Scale in an Italian population with Parkinson’s disease: A cross sectional study
ABSTRACT Background: The Berg Balance Scale is widely used to measure balance ability in clinical practice. Recently, the original version was redefined from 14 into 12 items. Its psychometric properties were investigated for different populations. However, for Parkinson disease the new version has not been validated yet. Objective: The purpose of the present study was to evaluate psychometric properties of the 12-item Berg Balance Scale (BBS-12) in a population with Parkinson disease. Methods: Internal consistency was evaluated with Cronbach ’ s alpha coefficient, whereas reliability was assessed with the intraclass...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research