E-096 COVID status is related to clot burden during thrombectomy in acute stroke patients

ConclusionOf 230 patients included in this interim analysis across 24 centers in the United States, between 02/2021 and 01/2022, 16 patients had a history of COVID. Comparing COVID-positive to non-positive, patients with COVID were younger (median 66.5 years vs 71.5 years, p 0.042), and had more intracranial clot by weight (median 101.0 mg vs 42.0 mg, p 0.047). There was a trend toward COVID positive patients to have more clot volume (median 180 cc vs 77.5 cc p 0.08), suggesting the difference was a higher clot burden instead of more density to the thrombus. These results suggest different histopathological characteristics in clot formation in COVID patients with large vessel occlusive stroke.Abstract E-096 Table 1 Sample Characteristics All Subjects(N=230) COVID(N=16) Non-COVID(N=214) P-Value1 Age 0.0416 N 230 16 214 Mean (SD) 69.2 (15.11) 60.4 (17.81) 69.9 (14.73) Median [IQR] 70.5 [59.0, 82.0] 66.5 [44.5, 74.5] 71.5 [59.0, 83.0] Range (min, max) (27.0, 98.0) (27.0, 83.0) (30.0, 98.0) Female 55.7% (128/230) 68.8% (11/16) 54.7% (117/214) 0.3090 Clot Weight (mg) 0.0471 N 225 15 210 Mean (SD) 91.7 (177.29) 114.5 (106.38) 90.1 (181.35) Median [IQR] 44.0 [19.0, 82.0] 101.0 [22.0, 172.0] 42.0 [18.0, 77.0] Range (min, max) (0.5, 1563.0) (1.0, 420.0) (0.5, 1563.0) Clot Volume (mm3) 0.0813 N 225 15 210 Mean (SD) 167.6 (366.14) 214.7 (225.07) 164.2 (374.32) Median [IQR] 80.0 [40.0, 150.0] 180.0 [36.0, 300.0] 77.5 [40.0, 132.0] Range (min, max) (1.0, 4500.0) (2.0, 900.0) (1....
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research