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Source: Neurochemical Research
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Total 300 results found since Jan 2013.
Adiponectin Promotes Neurogenesis After Transient Cerebral Ischemia Through STAT3 Mediated BDNF Upregulation in Astrocytes
In conclusion, adiponectin enhances neurogenesis and functional recovery after ischemic stroke via STAT3/BDNF pathway in astrocytes.PMID:36315369 | DOI:10.1007/s11064-022-03790-y
Source: Neurochemical Research - October 31, 2022 Category: Neuroscience Authors: Liang Yu Jiajia Wang Ying Xia Wugang Hou Xi Yao Yaru Guo Jin Wang Haidong Wei Shiquan Wang Source Type: research
Neuropeptide α-Melanocyte-Stimulating Hormone Promotes Neurological Recovery and Repairs Cerebral Ischemia/Reperfusion Injury in Type 1 Diabetes
In conclusion, α-MSH is neuroprotective under hyperglycemic condition against I/R induced brain damage by its anti-inflammatory, anti-oxidative and anti-apoptotic properties. The use of α-MSH analogues may be potential therapeutic agents for diabetic stroke.PMID:34586586 | DOI:10.1007/s11064-021-03453-4
Source: Neurochemical Research - September 29, 2021 Category: Neuroscience Authors: Rajesh Kumar Goit Tsz Chung Ng Ka Cheung Tam Jessica K W Tsang Andrew W Taylor Amy C Y Lo Source Type: research
Dose-Dependent Effects of Astaxanthin on Ischemia/Reperfusion Induced Brain Injury in MCAO Model Rat
Neurochem Res. 2022 Mar 14. doi: 10.1007/s11064-022-03565-5. Online ahead of print.ABSTRACTExcitotoxicity and oxidative stress are central to the pathology of the nervous system, and inhibition of excitotoxicity induced by glutamate is one of the therapeutic goals determined for stroke. The present study aimed to investigate the effects of Astaxanthin, a potent natural antioxidant, on complications caused by acute cerebral stroke. In this research, 60 male Wistar rats were used which were divided into 5 groups as follow: (1) the sham group (vehicle), (2) the ischemic control group (vehicle), and the ischemic groups treated...
Source: Neurochemical Research - March 14, 2022 Category: Neuroscience Authors: Forough Taheri Ehsan Sattari Maryam Hormozi Hassan Ahmadvand Mohammad Reza Bigdeli Parastou Kordestani-Moghadam Khatereh Anbari Sara Milanizadeh Mehrnoush Moghaddasi Source Type: research
Ischemia Reperfusion Injury Induced Blood Brain Barrier Dysfunction and the Involved Molecular Mechanism
Neurochem Res. 2023 Apr 5. doi: 10.1007/s11064-023-03923-x. Online ahead of print.ABSTRACTStroke is characterized by the abrupt failure of blood flow to a specific brain region, resulting in insufficient supply of oxygen and glucose to the ischemic tissues. Timely reperfusion of blood flow can rescue dying tissue but can also lead to secondary damage to both the infarcted tissues and the blood-brain barrier, known as ischemia/reperfusion injury. Both primary and secondary damage result in biphasic opening of the blood-brain barrier, leading to blood-brain barrier dysfunction and vasogenic edema. Importantly, blood-brain ba...
Source: Neurochemical Research - April 5, 2023 Category: Neuroscience Authors: Xi Guo Ru Liu Meng Jia Qun Wang Jianping Wu Source Type: research
