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Condition: Autoimmune Disease
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Total 293 results found since Jan 2013.
Association of autoimmune blistering disease, and specifically, pemphigus vulgaris, with cardiovascular disease and its risk factors: a systematic review and meta-analysis
The objective of the study was to systematically review the relationship of  AIBD, including pemphigus vulgaris (PV), and its treatment with CVD and CVD risk factors. MEDLINE, EMBASE, Cochrane, LILACS, SCOPUS, and Web of Science were searched. We included all studies of CVD and CVD risk factors in AIBD patients. Two reviewers performed title and/or abstract review and da ta extraction. Pooled random-effects meta-analysis was performed. Forty papers met inclusion criteria. AIBD was associated with higher odds of diabetes (DM) (odds ratio [95% confidence interval]: 1.809 [1.258–2.601]), hypertension (HTN) (1.393 [1.088â...
Source: Archives of Dermatological Research - March 9, 2022 Category: Dermatology Source Type: research
Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
CONCLUSIONS: 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.PMID:35396285 | DOI:10.1136/bmjopen-2021-054111
Source: Cancer Control - April 9, 2022 Category: Cancer & Oncology Authors: Peng Yeong Woon Jia-Ying Chien Jen-Hung Wang Yu-Yau Chou Mei-Chen Lin Shun-Ping Huang Source Type: research
Aging-Related Vascular Inflammation: Giant Cell Arteritis and Neurological Disorders
Front Aging Neurosci. 2022 Apr 12;14:843305. doi: 10.3389/fnagi.2022.843305. eCollection 2022.ABSTRACTAging is characterized by the functional decline of the immune system and constitutes the primary risk factor for infectious diseases, cardiovascular disorders, cancer, and neurodegenerative disorders. Blood vessels are immune-privileged sites and consist of endothelial cells, vascular smooth muscle cells, macrophages, dendritic cells, fibroblasts, and pericytes, among others. Aging also termed senescence inevitably affects blood vessels, making them vulnerable to inflammation. Atherosclerosis causes low-grade inflammation...
Source: Atherosclerosis - May 2, 2022 Category: Cardiology Authors: Ryu Watanabe Motomu Hashimoto Source Type: research
Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
Conclusions
74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.
Source: BMJ Open - April 8, 2022 Category: General Medicine Authors: Woon, P. Y., Chien, J.-Y., Wang, J.-H., Chou, Y.-Y., Lin, M.-C., Huang, S.-P. Tags: Open access, Ophthalmology Source Type: research
TREGking From Gut to Brain: The Control of Regulatory T Cells Along the Gut-Brain Axis
The human gastrointestinal tract has an enormous and diverse microbial community, termed microbiota, that is necessary for the development of the immune system and tissue homeostasis. In contrast, microbial dysbiosis is associated with various inflammatory and autoimmune diseases as well as neurological disorders in humans by affecting not only the immune system in the gastrointestinal tract but also other distal organs. FOXP3+ regulatory T cells (Tregs) are a subset of CD4+ helper T cell lineages that function as a gatekeeper for immune activation and are essential for peripheral autoimmunity prevention. Tregs are crucial...
Source: Frontiers in Immunology - June 30, 2022 Category: Allergy & Immunology Source Type: research
178 The association between bullous pemphigoid and schizophrenia: A systematic review and meta-analysis
Background: Bullous pemphigoid (BP) is a common autoimmune disorder characterized by pruritic, tense blisters. BP is often seen in the elderly and is associated with BP180 and BP230 autoantibodies against the epidermal basement membrane zone (BMZ) which result in blister formation via the separation of the dermis and epidermis. Earlier studies demonstrated an association between BP and various neurologic diseases such as stroke, Parkinson ’s disease, and dementia, but few have explored the relationship between BP and schizophrenia specifically.
Source: Journal of Investigative Dermatology - July 20, 2022 Category: Dermatology Authors: B. Cannata, F. Noor, W. Guo, K.W. Lu, S. Na, D. Lozeau Source Type: research
Clinical Characteristics  of Inpatients With New-Onset Diabetes Mellitus in Eastern China: Based on Novel Clustering Analysis
ConclusionsThe inpatients with new-onset diabetes in Eastern China had the unique clustering distribution. The clinical characteristics, treatments, and diabetes-related complications and comorbidities of the five subgroups were different, which may provide the basis for precise treatments of diabetes.
Source: Frontiers in Endocrinology - July 27, 2022 Category: Endocrinology Source Type: research
New insights into the comorbid conditions of Turner syndrome: results from a long-term monocentric cohort study
ConclusionsThis cohort study confirms the need for continuous, structured and multidisciplinary lifelong monitoring of TS, thus ensuring the early diagnosis of important comorbid conditions, including cancer, and their appropriate and timely treatment. In addition, these data highlight the need for the increased surveillance of specific types of cancer in TS, including thyroid carcinoma.
Source: Journal of Endocrinological Investigation - July 30, 2022 Category: Endocrinology Source Type: research
Cardiology co-management of rheumatoid arthritis patients with coronary artery disease as an intervention reduces hospitalization rates and adverse event occurrence
ConclusionPatients with regular cardiology follow-up demonstrated fewer cardiac-related adverse events. This suggests that co-management may have a role in adverse cardiac event risk reduction and should therefore be an early consideration.Key Points•Rheumatoid arthritis patients demonstrate higher rates of coronary disease compared to the general population. Traditional cardiac risk factors may not be entirely responsible for this phenomenon•Hospitalization rates and adverse event occurrence are significantly higher in patients with single-provider care (rheumatology only) compared to dual provider care (rheumatology ...
Source: Clinical Rheumatology - August 16, 2022 Category: Rheumatology Source Type: research
Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study
CONCLUSION: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors.PMID:36117577 | PMC:PMC9445874 | DOI:10.30476/IJMS.2021.89916.2068
Source: Atherosclerosis - September 19, 2022 Category: Cardiology Authors: Naeimehossadat Asmarian Farid Zand Parvin Delavari Vahid Khaloo Zahra Esmaeilinezhad Golnar Sabetian Yaldasadat Moeini Mohsen Savaie Fatemeh Javaherforooshzadeh Farhad Soltani Farid Yousefi Ebrahim Heidari Sardabi Maryam Haddadzadeh Shoushtari Anoush Dehn Source Type: research
Impact of Major Depressive Disorder on Comorbidities: A Systematic Literature Review
Conclusions: The presence of MDD was identified as a risk factor for both the development and the worsening of a range of comorbidities. These results highlight the importance of addressing depression early in its course and the need for integrating mental and general health care.PMID:36264099 | DOI:10.4088/JCP.21r14328
Source: Journal of Clinical Psychiatry - October 20, 2022 Category: Psychiatry Authors: Alix M Arnaud Teri S Brister Ken Duckworth Phyllis Foxworth Tonya Fulwider Ellison D Suthoff Brian Werneburg Izabela Aleksanderek Marcia L Reinhart Source Type: research
