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Condition: Autoimmune Disease
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Total 293 results found since Jan 2013.

Application and prospects of butylphthalide for the treatment of neurological diseases.
CONCLUSIONS: The varied pharmacological mechanisms of NBP involve many complex molecular mechanisms; however, there many unknown pharmacological effects await further study.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0. PMID: 31107716 [PubMed - as supplied by publisher]
Source: Chinese Medical Journal - May 12, 2019 Category: General Medicine Authors: Chen XQ, Qiu K, Liu H, He Q, Bai JH, Lu W Tags: Chin Med J (Engl) Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Application and prospects of butylphthalide for the treatment of neurologic diseases.
CONCLUSIONS: The varied pharmacologic mechanisms of NBP involve many complex molecular mechanisms; however, there many unknown pharmacologic effects await further study. PMID: 31205106 [PubMed - in process]
Source: Chinese Medical Journal - June 18, 2019 Category: General Medicine Authors: Chen XQ, Qiu K, Liu H, He Q, Bai JH, Lu W Tags: Chin Med J (Engl) Source Type: research

Antiphospholipid Syndrome is still a rare disease: the estimated prevalence in Piedmont and Aosta Valley
AbstractWe read with interest the recent article by Duarte ‐García, A. et al. where they reported an estimated prevalence of the antiphospholipid syndrome (APS) of 50 cases per 100,000 population. APS is an autoimmune disorder characterized by thrombotic events, pregnancy morbidity, or both in the presence of persistent positivity for antiphospholipid an tibodies (aPL). While APS is often held as the most common acquired thrombophilia, the global incidence and the prevalence of APS in the general population still need to be fully elucidated. Some reports estimate an incidence of 5 cases per 100,000 persons per year and ...
Source: Arthritis and Rheumatology - June 16, 2020 Category: Rheumatology Authors: Massimo Radin, Savino Sciascia, Mario Bazzan, Tiziana Bertero, Renato Carignola, Barbara Montaruli, Antonella Vaccarino, Erika Montabone, Irene Cecchi, Elena Rubini, Dario Roccatello, Simone Baldovino, on behalf of the Piedmont, Aosta Valley APS Consortiu Tags: LETTER TO THE EDITOR Source Type: research

Immunomodulatory Therapeutic Effects of Curcumin on M1 / M2 Macrophage polarization in Inflammatory Diseases
CONCLUSION: Curcumin not only enhances anti- tumor immunity (via shifting M polarization towards to M1 phenotype and/or up-regulation of M1 markers expression), but ameliorates inflammatory diseases including auto immune diseases (experimental autoimmune myocarditis and Behcet's disease), nephropathy, chronic serum sickness, stroke and atherosclerosis.PMID:35331128 | DOI:10.2174/1874467215666220324114624
Source: Atherosclerosis - March 25, 2022 Category: Cardiology Authors: Elham Abdollahi Thomas P Johnston Zahra Ghaneifar Parviz Vahedi Pouya Goleij Sara Azhdari Abbas Shapouri Moghaddam Source Type: research

E-061 Moyamoya syndrome patients have low vitamin D
ConclusionOur data indicate a large proportion of moyamoya syndrome patients are deficient in vitamin D, which we hypothesize contributes to pathological severity. Future studies incorporating vitamin D supplementation may act as a novel intervention for this patient population that currently has few treatment options.Disclosures J. Fraser: None. L. Whitnel: None. J. Roberts: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Whitnel, L., Roberts, J. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Exploring the molecular underpinning of psoriasis and its associated comorbidities through network approach: cross talks of genes and pathways
3 Biotech. 2023 May;13(5):130. doi: 10.1007/s13205-023-03533-y. Epub 2023 Apr 13.ABSTRACTPatients with psoriasis often complain of several linked disorders including autoimmune and cardiometabolic diseases. Understanding of molecular link between psoriasis and associated comorbidities would be of great interest at the point of patient care management. Integrative unbiased network approach, indicates significant unidirectional gene overlap between psoriasis and its associated comorbid condition including obesity (31 upregulated and 26 downregulated), ischemic stroke (14 upregulated and 2 downregulated), dyslipidaemia (5 upr...
Source: Atherosclerosis - April 17, 2023 Category: Cardiology Authors: Saumya Choudhary Noor Saba Khan Rashi Verma Pallavi Saxena Harpreet Singh Arun Kumar Jain George Thomas Dibyabhaba Pradhan Neeraj Kumar Source Type: research

Observational Study of Patients Hospitalized With Neurologic Events After SARS-CoV-2 Vaccination, December 2020-June 2021
Discussion All cases in this study were determined to have at least 1 risk factor and/or known etiology accounting for their neurologic syndromes. Our comprehensive clinical review of these cases supports the safety of mRNA COVID-19 vaccines.
Source: Neurology Clinical Practice - May 25, 2023 Category: Neurology Authors: Kim, C. Y., McNeill, E. N., Young, C., King, F., Clague, M., Caldwell, M., Boruah, A., Zucker, J., Thakur, K. T. Tags: Autoimmune diseases, Post-infectious, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), COVID-19 Research Article Source Type: research

Scientists Are Just Beginning to Understand COVID-19 ’ s Effect On the Brain
Early in the COVID-19 pandemic, doctors started to notice something striking. For what was originally described as a respiratory virus, SARS-CoV-2 seemed to have a strong effect on the brain, causing everything from loss of taste and smell and brain fog to, in serious cases, stroke. NYU Langone Health, a New York city research hospital, started collating those anecdotes in hopes of better understanding how the virus affects the brain and nervous system. Years later, the project has morphed from focusing solely on acute symptoms to also tracking the long-term neurologic issues that some people with Long COVID experience, sa...
Source: TIME: Health - July 17, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

A patient with MELAS syndrome combined with autoimmune abnormalities: a case report
ConclusionMitochondrial encephalomyopathy is a rare clinical condition; however, the association with autoimmune diseases is not yet clear and still needs further research and analysis.
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Prophylactic dose fondaparinux for 6 weeks in superficial thrombophlebitis of the legs reduces the risk for symptomatic thromboembolic complications
Commentary on: Di Nisio M, Wichers IM, Middeldorp S. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev 2012;3:CD004982. Context Superficial thrombophlebitis (ST), an inflammatory-thrombotic disorder in a superficial vein, is relatively common and estimated to occur in 1 per 1000 persons.1 The classic symptoms include pain, oedema, erythema and occasionally a palpable cord in the area of the thrombosed vein. Risk factors for ST include surgery, pregnancy and puerperium, female hormones, malignancy, infection, varicose veins, autoimmune disorders and thrombophilia.2 ST is a risk factor for dee...
Source: Evidence-Based Medicine - January 17, 2013 Category: Internal Medicine Authors: DeSancho, M. T., Pastores, S. M. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Pain (neurology), Stroke, Pregnancy, Venous thromboembolism, Renal medicine, Pulmonary embolism, Drugs: musculoskeletal and joint diseases, Dermatology Therapeutics Source Type: research

Cystatin C as a Marker of Degeneration in Multiple Sclerosis (P03.241)
CONCLUSIONS: Cystatin C concentration decrease in RR form of MS could give evidence for high disease activity in this stage of the disease with high myelin damage and neurodegeneration.Supported by: Grant IGA MHCZ NT 12221-5/2010.Disclosure: Dr. Prikrylová Vranová has nothing to disclose. Dr. Sládková has nothing to disclose. Dr. Mares has nothing to disclose. Dr. Hlustík has nothing to disclose. Dr. Langová has nothing to disclose. Dr. Kanovsky has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Prikrylova Vranova, H., Sladkova, V., Mares, J., Hlustik, P., Langova, J., Kanovsky, P. Tags: P03 Multiple Sclerosis: Disease Biomarkers Source Type: research

Even 'light' smoking may raise women's arthritis risk
Conclusion This research indicates that a relatively low level of smoking (one to seven cigarettes per day) is associated with an increased risk of developing rheumatoid arthritis compared with women who had never smoked. This adds further knowledge to previous research that has suggested that cigarette smoking is directly linked to a higher risk of developing rheumatoid arthritis. While this study is relatively robust and its results believable, it does have limitations that should be considered. It was not clear how many women dropped out of the study. If this was a large proportion of the women who started, it could si...
Source: NHS News Feed - April 23, 2013 Category: Consumer Health News Tags: Cancer Heart/lungs Lifestyle/exercise Source Type: news