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Total 1014 results found since Jan 2013.

An unusual cause of ischemic stroke - Cerebral air embolism
We describe the case and neuroimaging of a patient with ischaemic stroke due to air embolism during manipulation of central venous line. We also review the literature with respect to aetiology, incidence pathophysiology, diagnosis, and treatment options for venous and air embolism. Cerebral air embolism should be considered in patients with sudden neurological deterioration after central venous or arterial manipulations or certain neurological procedures. Prevention, as well as early diagnosis and management, may reduce morbidity and mortality.
Source: Annals of Indian Academy of Neurology - March 12, 2014 Category: Neurology Authors: Vinit SuriRohan GuptaGirraj SharmaKunal Suri Source Type: research

Acute stroke-like presentation of acquired hepatocerebral degeneration
B. Smita, V. Abdul Gafoor, K. Saifudheen, James JoseAnnals of Indian Academy of Neurology 2014 17(2):204-206Neurological manifestations in liver diseases have been well-described. Parkinsonism developing in cirrhotic patients is a unique clinical, neuroradiological, and biological entity. The symptoms are often insidious in onset and occur after liver disease has made its presentation. Acute dysarthria as the presenting manifestation of cirrhosis is rare. Here we report three cases where liver disease made an unusual presentation as acute dysarthria. In all cases the abruptness of the onset prompted the treating physicians...
Source: Annals of Indian Academy of Neurology - May 17, 2014 Category: Neurology Authors: B. SmitaV. Abdul GafoorK. SaifudheenJames Jose Source Type: research

Stroke prevention in atrial fibrillation: Commentary regarding the AAN's evidence-based guideline update
We thank Drs. Hart and Eikelboom1 for their insightful commentary in Neurology® Clinical Practice regarding the American Academy of Neurology (AAN) evidence-based guideline update on atrial fibrillation (AF).2 Both authors have extensively researched stroke prevention in patients with AF3 and we respect their views. The Commentary states, "atrial fibrillation patients with prior ischemic stroke or TIA benefit the most from anticoagulation and should receive anticoagulation, if it can be given safely." We could not agree more. The AAN guideline development process yields a Level B recommendation when clinicians "should"...
Source: Nature Clinical Practice - June 9, 2014 Category: Neurology Authors: Culebras, A., Messe, S. R. Tags: The Nerve! Readers Speak Source Type: research

Inability to Consent Does not Diminish the Desirability of Stroke Thrombolysis
Recently, the American Academy of Neurology and the American Heart Association/American Stroke Association have endorsed the use of thrombolysis in incapacitated persons without surrogate decision makers. The rationale for this position is that a reasonable person would consent to treatment if asked. The goal of this study was to evaluate the influence of the inability to consent and of personal health-related values on older adults’ emergency treatment preferences for both ischemic stroke and cardiac arrest.
Source: The Journal of Emergency Medicine - December 25, 2014 Category: Emergency Medicine Authors: Skylar Johnson Tags: Abstracts Source Type: research

Mineralizing angiopathy with basal ganglia stroke in an infant
We report an infant who developed basal ganglia stroke following trivial fall. His clinic-radiological features are described.
Source: Annals of Indian Academy of Neurology - May 8, 2015 Category: Neurology Authors: Puneet JainPraveen KishoreJasjit Singh BhasinSubhash Chand Arya Source Type: research

Early testing can predict the stroke patients who will develop upper limb spasticity
(University of Gothenburg) Many stroke patients suffer from spasticity of the arm that cause pain and impaired sensorimotor function. But there are ways of identifying such patients ahead of time so that they can obtain the earliest possible treatment. Researchers at Sahlgrenska Academy have completed a study of stroke patients in the Gothenburg area.
Source: EurekAlert! - Medicine and Health - September 23, 2015 Category: Global & Universal Source Type: news

Nonvitamin K antagonist oral anticoagulants in everyday practice: Stroke prevention in atrial fibrillation and treatment of venous thromboembolism
ConclusionsAll four NOACs are equivalent to or better than warfarin for the treatment of VTE and stroke prevention in AF, and may reduce the risk of bleeding complications, particularly intracranial bleeding. Implications for practiceNOACs may benefit some patients by avoiding the numerous food or drug interactions and frequent laboratory monitoring associated with warfarin. Adherence to proper dosing is critical for NOAC efficacy and safety.
Source: Journal of the American Academy of Nurse Practitioners - December 17, 2015 Category: Nursing Authors: Barbara A. Bentz Tags: REVIEW Source Type: research

Connectivity changes predict deficit after stroke Neuroscience
Deficits following stroke are classically attributed to focal damage, but recent evidence suggests a key role of distributed brain network disruption. We measured resting functional connectivity (FC), lesion topography, and behavior in multiple domains (attention, visual memory, verbal memory, language, motor, and visual) in a cohort of 132 stroke patients,...
Source: Proceedings of the National Academy of Sciences - July 25, 2016 Category: Science Authors: Siegel, J. S., Ramsey, L. E., Snyder, A. Z., Metcalf, N. V., Chacko, R. V., Weinberger, K., Baldassarre, A., Hacker, C. D., Shulman, G. L., Corbetta, M. Tags: PNAS Plus Source Type: research

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a Pharmacology
Stroke is the second-leading cause of death worldwide, yet there are no drugs available to protect the brain from stroke-induced neuronal injury. Acid-sensing ion channel 1a (ASIC1a) is the primary acid sensor in mammalian brain and a key mediator of acidosis-induced neuronal damage following cerebral ischemia. Genetic ablation and selective...
Source: Proceedings of the National Academy of Sciences - April 4, 2017 Category: Science Authors: Irene R. Chassagnon, Claudia A. McCarthy, Yanni K.–Y. Chin, Sandy S. Pineda, Angelo Keramidas, Mehdi Mobli, Vi Pham, T. Michael De Silva, Joseph W. Lynch, Robert E. Widdop, Lachlan D. Rash, Glenn F. King Tags: Biological Sciences Source Type: research

Translation and adaptation of stroke aphasia depression questionnaire-10 to Hindi
Conclusions: SADQ10-Hindi may assist the identification of depressed mood in patients with speech and language impairment in an Indian population as well. It is an easy to administer and quick test which can be used by health-care professionals in a hospital- or community-based settings.
Source: Annals of Indian Academy of Neurology - May 8, 2017 Category: Neurology Authors: Harsimarpreet Kaur Sakshi Chopra RM Pandey Rohit Bhatia Ashima Nehra Source Type: research

Intravenous Recombinant Tissue Plasminogen Activator and Ischemic Stroke: Focused Update of 2010 Clinical Practice Advisory From the American Academy of Emergency Medicine
Stroke treatment is a continuum that begins with the rapid identification of symptoms and treatment with transition to successful rehabilitation. Therapies for acute ischemic stroke (AIS) may vary based on anatomic location, interval from symptom onset, and coexisting health conditions. Successful therapy requires a seamless systematic approach with coordination from prehospital environment through acute management at medical facilities to disposition and long-term care of the patient. The emergency physician must balance the benefits and risks of alteplase recombinant tissue plasminogen activator (rtPA) for AIS management.
Source: The Journal of Emergency Medicine - March 12, 2018 Category: Emergency Medicine Authors: William J. Meurer, Bradley Barth, Michael Abraham, Jerome Hoffman, Gary M. Vilke, Gerard DeMers Tags: AAEM Clinical Practice Source Type: research

Stroke affects more than just the physical
(American Academy of Neurology) A new study looks at what problems affect people most after a stroke and it provides a broader picture than what some may usually expect to see. Stroke affects more than just physical functioning, according to a study is published the March 28, 2018, online issue of Neurology ® , the medical journal of the American Academy of Neurology.
Source: EurekAlert! - Social and Behavioral Science - March 28, 2018 Category: International Medicine & Public Health Source Type: news

Intravenous Recombinant Tissue Plasminogen Activator and Ischemic Stroke: Focused Update of 2010 Clinical Practice Advisory From the American Academy of Emergency Medicine
Stroke treatment is a continuum that begins with the rapid identification of symptoms and treatment with transition to successful rehabilitation. Therapies for acute ischemic stroke (AIS) may vary based on anatomic location, interval from symptom onset, and coexisting health conditions. Successful therapy requires a seamless systematic approach with coordination from prehospital environment through acute management at medical facilities to disposition and long-term care of the patient. The emergency physician must balance the benefits and risks of alteplase recombinant tissue plasminogen activator (rtPA) for AIS management.
Source: The Journal of Emergency Medicine - March 12, 2018 Category: Emergency Medicine Authors: William J. Meurer, Bradley Barth, Michael Abraham, Jerome R. Hoffman, Gary M. Vilke, Gerard DeMers Tags: AAEM Clinical Practice Source Type: research

Elastic coupling power stroke mechanism of the F1-ATPase molecular motor Biochemistry
The angular velocity profile of the 120° F1-ATPase power stroke was resolved as a function of temperature from 16.3 to 44.6 °C using a ΔμATP = −31.25 kBT at a time resolution of 10 μs. Angular velocities during the first 60° of the power stroke (phase 1) varied inversely with...
Source: Proceedings of the National Academy of Sciences - May 29, 2018 Category: Science Authors: James L. Martin, Robert Ishmukhametov, David Spetzler, Tassilo Hornung, Wayne D. Frasch Tags: Biological Sciences Source Type: research

Comparison of best medical management with carotid intervention procedures in the prevention of stroke recurrence in patients with symptomatic internal carotid artery stenosis
Conclusions: Overall, there was no statistically significant difference in the rate of recurrence between the best medical management and the carotid interventional procedures.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: BV Deepa Rani Sandeep Gampa Deepika Sirineni KR Harshavardhana Satya Rama Krishna Subhash Kaul Source Type: research