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Total 1014 results found since Jan 2013.

Wake-up Stroke and Onset-to-door Duration Delays: Potential Future Indications for Reperfusion Therapy.
Conclusion: The one- third proportion of wake-up stroke in this cohort and low prevalence of relative contraindications suggest this is a promising group for emerging thrombolysis indications. With the majority of patients presenting after 8 hours, widening of the therapeutic window with new potential reperfusion treatments would not appreciably increase treatment utilisation. This study reaffirms the urgent need for public education to improve stroke awareness in Singapore. PMID: 24557460 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2014 Category: Journals (General) Authors: Tan MSh, Ang ES, Ho SS, Ng SC, Talabucon L, Woon FP, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Hyponatremia in stroke
Conclusion: Incidence of hyponatremia in our study population was 35%. In patients of hyponatremia 67% were having SIADH and 33% were having CSWS. Overall hyponatremia affected the outcome of stroke especially when caused by CSWS. Therefore close monitoring of serum sodium must be done in all patients who are admitted with stroke and efforts must be made to determine the cause of hyponatremia, in order to properly manage such patients thereby decreasing the mortality rate.
Source: Annals of Indian Academy of Neurology - March 12, 2014 Category: Neurology Authors: Sheikh SaleemIrfan YousufAzhara GulSatish GuptaSawan Verma Source Type: research

Factors delaying hospital arrival of patients with acute stroke
Conclusions: We found a considerable delay in the early arrival of patients to our stroke department. Health promotion strategies to improve community awareness of early symptoms of stroke, education of local physicians about the importance of early referrals to the stroke centers, and wider availability and use of ambulance services are promising methods to help expedite presentation to hospital post stroke and thereby improve the management of stroke in India.
Source: Annals of Indian Academy of Neurology - May 8, 2015 Category: Neurology Authors: VV AshrafM ManeeshR PraveenkumarK SaifudheenAS Girija Source Type: research

Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603 838 individuals
Publication date: Available online 19 August 2015 Source:The Lancet Author(s): Mika Kivimäki, Markus Jokela, Solja T Nyberg, Archana Singh-Manoux, Eleonor I Fransson, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr, Annalisa Casini, Els Clays, Dirk De Bacquer, Nico Dragano, Raimund Erbel, Goedele A Geuskens, Mark Hamer, Wendela E Hooftman, Irene L Houtman, Karl-Heinz Jöckel, France Kittel, Anders Knutsson, Markku Koskenvuo, Thorsten Lunau, Ida E H Madsen, Martin L Nielsen, Maria Nordin, Tuula Oksanen, Jan H Pejtersen, Jaana Pentti, Reiner Rugulies, Paula Salo, Martin J S...
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

Role of brain natriuretic peptide as a novel prognostic biomarker in acute ischemic stroke
Conclusion: Plasma BNP levels was significantly elevated in patients with ischemic stroke. Our study concludes that high BNP levels are seen in large anterior circulation stroke and is a predictor for the poor functional outcome at 3 months. Determination of BNP levels as a biomarker could be helpful in predicting the outcome in stroke patients.
Source: Annals of Indian Academy of Neurology - November 21, 2016 Category: Neurology Authors: Bindu Menon Krishnana Ramalingam Jyoti Conjeevaram K Munisusmitha Source Type: research

Surveys of Stroke Patients and Their Next of Kin on Their Opinions towards Decision-Making and Consent for Stroke Thrombolysis.
CONCLUSION: The survey found that in the decision-making process for stroke thrombolysis, there was no clear consensus on the preference for the decision maker of the mentally incapacitated patient. In Singapore, there is a strong influence of the NOK in decision-making for thrombolysis. PMID: 28263342 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 31, 2017 Category: Journals (General) Authors: Angamuthu N, Queck KK, Menon S, Ho SS, Ang E, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Validation of marathi version of stroke-specific quality of life
Conclusion: Marathi version of SSQOL is a valid, reliable instrument for measuring self-reported health-related quality of life in patients with stroke.
Source: Annals of Indian Academy of Neurology - November 2, 2018 Category: Neurology Authors: Suvarna Ganvir Maheshwari Harishch Chetana Kunde Source Type: research

Severely Disturbed Sleep in Patients With Acute Ischemic Stroke on Stroke Units: A Pilot Study
Conclusion: We show that sleep is severely disturbed in patients with acute ischemic stroke admitted to stroke units. Larger studies are needed to clarify associations between deprivation of deep sleep and secondary deterioration.
Source: Frontiers in Neurology - October 24, 2019 Category: Neurology Source Type: research

Stem cell therapy in ischemic stroke: A systematic review and meta-analysis of randomized controlled trials
Conclusion: Our meta-analysis provides no clinically important evidence for efficacy of stem cells in reducing neurological deficit compared to control group. Well-designed large randomized controlled trials are required to provide more information on the efficacy of stem cell therapy in patients with IS.
Source: Annals of Indian Academy of Neurology - April 28, 2021 Category: Neurology Authors: Amit Kumar Dimple Rawat Kameshwar Prasad Source Type: research

Clinical features and outcome of stroke with COVID-19. COVID-19 Stroke Study Group (CSSG), India
Conclusions: CoVS is associated with higher severity, poor outcome, and increased mortality. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and baseline stroke severity are independent predictors of mortality.
Source: Annals of Indian Academy of Neurology - December 4, 2021 Category: Neurology Authors: Rohit Bhatia MV Padma Srivastava PN Sylaja Snigdha Komakula Ashish Upadhyay Vibhor Pardasani Thomas Iype Rajsrinivas Parthasarathy Rajshekhar Reddy Suman Kushwaha Jayanta Roy P Satish Anjan Trikha Naveet Wig Lalit Dhar Deepti Vibha Venugopalan Y Vishnu Aw Source Type: research

A scoping review of recent advancements in intervention and outcome measures for post-stroke cognitive impairments
Conclusion: Regardless of many new developments in post-stroke cognitive rehabilitation interventions driven by technology, there is limited data available on actual implementation as a scalable solution. There is an extensive need for future research for evidence-based assessment and management of cognitive impairments in post-stroke rehabilitation.
Source: Annals of Indian Academy of Neurology - January 27, 2023 Category: Neurology Authors: Dimple Dawar Sureshkumar Kamalakannan Nistara S Chawla Jibil T Mathew Esha Mehmood Unnati Bhatnagar Jeyaraj Durai Pandian Source Type: research

Public awareness of sepsis and stroke in singapore: a population-based survey.
Conclusion: Our findings reflect the differences in the public profile of sepsis versus stroke in Singapore. More concerted efforts involving healthcare professionals, medical societies, statutory boards, and the mass media are required to improve public awareness of these 2 conditions -especially sepsis. PMID: 23842767 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 1, 2013 Category: Journals (General) Authors: Phua J, Lim HF, Tay CK, Aung NW Tags: Ann Acad Med Singapore Source Type: research

Low-density lipoprotein subfraction, carotid artery intima-media thickness, nitric oxide, and tumor necrosis factor alpha are associated with newly diagnosed ischemic stroke
Conclusion: These results show that sd-LDL is independently associated with the incidence of stroke and may be a risk factor in the development of stroke. In addition, TNF-a, NO, right CIMT, and left CIMT may be a risk factor in the development of ischemic stroke.
Source: Annals of Indian Academy of Neurology - October 25, 2013 Category: Neurology Authors: Medine Cumhur CureAhmet TufekciErkan CureSerkan KirbasSabri OgullarAynur KirbasHuseyin UnalSuleyman YuceSevim Cakmak Source Type: research

Attitudes and Practices on the Consent Process and Decision-making for Intravenous Stroke Thrombolysis: Physicians' Perspective.
Conclusion: The next-of-kin is usually the decision-maker for stroke thrombolysis in practice for a mentally incapacitated patient despite most doctors considering thrombolysis an emergency treatment. This, together with the lack of consensus and variance in decision-making and consent practice amongst neurologists for stroke thrombolysis, demonstrates the need to develop best practice guidelines to standardise healthcare practices for greater consistency in health service delivery. PMID: 24356652 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - November 1, 2013 Category: Journals (General) Authors: Talabucon LP, Menon S, Toh AJ, Oh DC, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Clinicoanatomical correlation in stroke related aphasia
Conclusions: No absolute correlation exists between the lesion site and the type of clinical aphasia syndrome in majority of the patients with cortical and subcortical stroke.
Source: Annals of Indian Academy of Neurology - November 17, 2015 Category: Neurology Authors: Vikram BohraGeeta Anjum KhwajaSneh JainAshish DuggalVijay Vishwanath GhugeAbhilekh Srivastava Source Type: research