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Total 1014 results found since Jan 2013.

The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants.
Abstract The last ten years have seen rapid strides in the evolution of nonvitamin K oral anticoagulants (NOACs) for stroke prevention in patients with atrial fibrillation (AF). For the preparation of this consensus, a comprehensive literature search was performed and data on available trials, subpopulation analyses, and case reports were analyzed. This Indian consensus document intends to provide guidance on selecting the right NOAC for the right patients by formulating expert opinions based on the available trials and Asian/Indian subpopulation analyses of these trials. A section has been dedicated to the curren...
Source: Indian Heart J - December 1, 2015 Category: Cardiology Authors: Dalal J, Bhave A, Oomman A, Vora A, Saxena A, Kahali D, Poncha F, Gambhir DS, Chaudhuri JR, Sinha N, Ray S, Iyengar SS, Banerjee S, Kaul U, SPAF Academy India experts Tags: Indian Heart J Source Type: research

Brazilian guidelines for endovascular treatment of patients with acute ischemic stroke
ABSTRACT These guidelines are the result of a joint effort from writing groups of the Brazilian Stroke Society, the Scientific Department of Cerebrovascular Diseases of the Brazilian Academy of Neurology, the Brazilian Stroke Network and the Brazilian Society of Diagnostic and Therapeutic Neuroradiology. Members from these groups participated in web-based discussion forums with predefined themes, followed by videoconference meetings in which controversies and position statements were discussed, leading to a consensus. This guidelines focuses on the implications of the recent clinical trials on endovascular therapy for acut...
Source: Arquivos de Neuro-Psiquiatria - January 16, 2017 Category: Neurology Source Type: research

Transforming growth factor- & #946;1 (C509T, G800A, and T869C) gene polymorphisms and risk of ischemic stroke in North Indian population: A hospital-based case-control study
Conclusion: Our results suggest that TGF-β1 polymorphisms and their haplotypes are significantly associated with the risk of IS in North Indian population.
Source: Annals of Indian Academy of Neurology - February 8, 2017 Category: Neurology Authors: Pradeep Kumar Shubham Misra Amit Kumar Mohammad Faruq Sunil Shakya Gyan Vardhan Subiah Vivekanandhan Achal Kumar Srivastava Kameshwar Prasad Source Type: research

The need for a population-based, dose optimization study for recombinant tissue plasminogen activator in acute ischemic stroke: A study from a tertiary care teaching hospital from South India
Conclusion: There is a need for a properly randomized, dose optimization study of i.v rt-PA in the Indian subcontinent.
Source: Annals of Indian Academy of Neurology - February 8, 2017 Category: Neurology Authors: Siju V Abraham Fazil Thaha S Vimal Krishnan Athulya Shajan Jayaraj Mymbilly Balakrishnan Babu Urumese Palatty Source Type: research

Alpha-1 antitrypsin dysfunction and large artery stroke Biochemistry
Ischemic stroke—that is, cerebral infarction causing stroke symptoms—is pathophysiologically and phenotypically heterogeneous. To address this heterogeneity, investigators have often chosen to study the genetics of ischemic stroke according to its less-heterogeneous phenotypes. Many systems have been developed and deployed for classifying ischemic stroke into subphenotypes. In pursuit of gene discovery,...
Source: Proceedings of the National Academy of Sciences - April 4, 2017 Category: Science Authors: James F. Meschia Tags: Commentaries Source Type: research

Relationship between factor V leiden gene variant and risk of ischemic stroke: A case & #8211;control study
Conclusion: The present study suggests that Factor V Leiden G1691A polymorphism may be significantly associated with the risk of large vessel subtype of IS. Large sample size studies using prospective cohort designs are required to corroborate the present findings.
Source: Annals of Indian Academy of Neurology - August 10, 2017 Category: Neurology Authors: Amit Kumar Shubham Misra Ram Sagar Pradeep Kumar Arun K Yadav Pumanshi Talwar Ritesh Raj Kameshwar Prasad Source Type: research

Sung melody enhances verbal learning and recall after stroke
Abstract Coupling novel verbal material with a musical melody can potentially aid in its learning and recall in healthy subjects, but this has never been systematically studied in stroke patients with cognitive deficits. In a counterbalanced design, we presented novel verbal material (short narrative stories) in both spoken and sung formats to stroke patients at the acute poststroke stage and 6 months poststroke. The task comprised three learning trials and a delayed recall trial. Memory performance on the spoken and sung tasks did not differ at the acute stage, whereas sung stories were learned and recalled significantly ...
Source: Annals of the New York Academy of Sciences - March 15, 2018 Category: Science Authors: Vera Leo, Aleksi J. Sihvonen, Tanja Linnavalli, Mari Tervaniemi, Matti Laine, Seppo Soinila, Teppo S ärkämö Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of cranial electrical stimulation and rational emotive behavior therapy in improving psychological illness among chronic stroke survivors: A pilot randomized controlled trial
Conclusion: CES has the potential to improve psychological illness such as depression, anxiety, stress, attitudes, belief, and thereby quality of life among CS survivors than REBT.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Meenu Bhardwaj Narkeesh Arumugam Shefali Gambhir Source Type: research

Predictors of intracerebral hemorrhage in acute stroke patients receiving intravenous recombinant tissue plasminogen activator
Conclusion: High NIHSS score, increased stroke onset to thrombolysis time , high blood sugar at presentation ,prior diabetes and hypertension increase the chances of sICH. None of these contraindicate thrombolysing strokes but should caution the physician.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Vijay Chenna Subhash Kaul Swetha Tandra Sireesha Yareeda Neeharika Mathukumalli Abhijeet Kumar Kohat Rukmini Mridula Kandadai Suryaprabha Turaga Jabeen Afshan Sheik AK Meena Rupam Borgohain Source Type: research

Partitioning Stroke Patients, Determining Related Factors, and Comparing Derived Clusters Based on 12-Month Health Outcomes.
CONCLUSION: Considering the modifiable risk factors identified in the current study, providing programs for preventing readmission and potential death caused by stroke for Clusters 3 and 5 seems essential. PMID: 31823622 [PubMed - in process]
Source: Archives of Iranian Medicine - November 30, 2019 Category: Middle East Health Authors: Soroush A, Sariaslani P, Baharirad N, Shams-Alizadeh N, Komasi S Tags: Arch Iran Med Source Type: research

Endovascular Treatment for Acute Tandem Occlusion Stroke: Results from Case Series of 17 Patients
Conclusion: Our study determined a promising outcome with reasonable good recanalization and clinical recovery for endovascular intervention in tandem ischemic. In the subgroup of treatment, “extracranial stent first” had more complex disease with completed ICA occlusion which required longer procedure time may lead to worse outcome.
Source: Annals of Indian Academy of Neurology - January 20, 2020 Category: Neurology Authors: Luu Vu-Dang Quang-Anh Nguyen Trang Nguyen-Thi-Thu Anh-Tuan Tran Cong Le-Chi Kien Le-Hoang Thien Nguyen-Tat An Nguyen-Huu Thong Pham-Minh Thien Chu-Dinh Dinh-Toi Chu Source Type: research

Management of acute stroke and urgent neurointerventional procedures during COVID-19 pandemic: recommendations on the Scientific Department on Cerebrovascular Diseases of the Brazilian Academy of Neurology, Brazilian Society of Cerebrovascular Diseases and Brazilian Society of Neuroradiology
ABSTRACT Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that with an inefficient treatment will further increase mortality and long-term disability. Objective: This paper summar...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Development and validation of a comprehensive neuropsychological and language rehabilitation for stroke survivors: A home-based caregiver-delivered intervention program
Conclusions: This intervention can be feasible to administer as a home-based intervention and may help to alleviate language and neuropsychological complaints after stroke in low-literate or mixed-cultural populations. Further, large sample size studies are recommended.
Source: Annals of Indian Academy of Neurology - September 24, 2020 Category: Neurology Authors: Harsimarpreet Kaur Ashima Nehra Sakshi Chopra Hemchandra Sati Rohit Bhatia Senthil S Kumaran RM Pandey MV Padma Srivastava Source Type: research

Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans Neuroscience
Restoration of human brain function after injury is a signal challenge for translational neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for intensive motor training after stroke: near-full recovery is attained if task-specific motor training occurs during this sensitive window. We extended these findings to adult humans...
Source: Proceedings of the National Academy of Sciences - September 20, 2021 Category: Science Authors: Alexander W. Dromerick, Shashwati Geed, Jessica Barth, Kathaleen Brady, Margot L. Giannetti, Abigail Mitchell, Matthew A. Edwardson, Ming T. Tan, Yizhao Zhou, Elissa L. Newport, Dorothy F. Edwards Tags: Neuroscience Biological Sciences Source Type: research