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Condition: Hypertension
Procedure: Perfusion
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Total 203 results found since Jan 2013.
Left atrial enlargement increases the risk of major adverse cardiac events independent of coronary vasodilator capacity
Conclusion
LAE and reduced CFR are related but distinct cardiovascular adaptations to atherogenic risk factors. LAE is a risk marker for MACE independent of clinical factors and left ventricular volumes; individuals with LAE may be at risk of MACE despite normal coronary vascular function.
Source: European Journal of Nuclear Medicine and Molecular Imaging - August 1, 2015 Category: Nuclear Medicine Source Type: research
Effect of hypertension and carotid occlusion on brain parenchymal arteriole structure and reactivity
We studied the effect of hypertension and chronic hypoperfusion on brain parenchymal arteriole (PA) structure and function. PAs were studied isolated and pressurized from 18-wk-old Wistar-Kyoto (WKY18; n = 8) and spontaneously hypertensive stroke prone (SHRSP18; n = 8) and 5-wk-old prehypertensive (SHRSP5; n = 8) rats. In separate groups, unilateral common carotid artery occlusion (UCCAo) was performed for 4 wk to cause chronic hypoperfusion in 18-wk-old WKY (WKY18-CH; n = 8) and SHRSP (SHRSP18-CH; n = 8). UCCAo caused PAs to have significantly diminished myogenic tone (31 ± 3 vs. 14 ± 6% at 60 mmHg; P < 0...
Source: Journal of Applied Physiology - October 1, 2015 Category: Physiology Authors: Sweet, J. G., Chan, S.-L., Cipolla, M. J. Tags: ARTICLES Source Type: research
Hemodynamic Significance of Internal Carotid or Middle Cerebral Artery Stenosis Detected on Magnetic Resonance Angiography.
CONCLUSION: A considerable proportion of ICA-MCA stenosis detected on MRA does not cause CVR impairment despite a fair correlation between them. Thus, hemodynamic state needs to be assessed for evaluating significance of stenosis, particularly in asymptomatic patients.
PMID: 26446655 [PubMed - in process]
Source: Yonsei Medical Journal - October 9, 2015 Category: Universities & Medical Training Authors: Seo HJ, Pagsisihan JR, Paeng JC, Choi SH, Cheon GJ, Chung JK, Lee DS, Kang KW Tags: Yonsei Med J Source Type: research
Abstract P015: Bilateral Common Carotid Artery Stenosis in Hypertensive Rats Impairs Dilation in Penetrating Arterioles and Posterior Communicating Arteries Session Title: Poster Session 1- Trainee Onsite Poster Competition and Reception
Hypertension and chronic cerebral hypoperfusion (CCH) are leading risk factors for cognitive impairment. We induced hypoperfusion in stroke prone spontaneously hypertensive rats (SHRSP) by bilateral carotid artery stenosis (BCAS) to create a novel, physiologically relevant model of cognitive impairment. We hypothesized that BCAS in SHRSP would impair endothelium dependent dilation and lead to outward remodeling of the penetrating arterioles (PAs) and posterior cerebral arteries (PCAs). The PAs are critical for maintaining parenchymal perfusion and controlling blood flow to the neurovascular unit, and the PCAs are integral ...
Source: Hypertension - November 3, 2015 Category: Cardiology Authors: Matin, N., Fisher, C., Jackson, W. F., Dorrance, A. M. Tags: Session Title: Poster Session 1- Trainee Onsite Poster Competition and Reception Source Type: research
Winter metabolic depression does not change arterial baroreflex control of heart rate in the tegu lizard (Salvator merianae) RESEARCH ARTICLE
Lucas A. Zena, Valter Dantonio, Luciane H. Gargaglioni, Denis V. Andrade, Augusto S. Abe, and Kenia C. BicegoBaroreflex regulation of blood pressure (BP) is important for maintaining appropriate tissue perfusion. Although temperature affects heart rate (fH) reflex regulation in some reptiles and toads, no data are available on the influence of temperature-independent metabolic states on baroreflex. The South American tegu lizard Salvator merianae exhibits a clear seasonal cycle of activity decreasing fH along with winter metabolic downregulation, independent of body temperature. Through pharmacological interventions (pheny...
Source: Journal of Experimental Biology - January 8, 2016 Category: Biology Authors: Zena, L. A., Dantonio, V., Gargaglioni, L. H., Andrade, D. V., Abe, A. S., Bicego, K. C. Tags: RESEARCH ARTICLE Source Type: research
Rigorous anaesthesia management protocol for patients with intracranial arterial stenosis: a prospective controlled-cohort study
Conclusions
The ERSIAS anaesthesia protocol successfully reduced intraoperative fluctuations of MAP and ETCO2. The protocol also achieved normocarbia and the intended hypertension.
Trial registration number
NCT01819597; Pre-results.
Source: BMJ Open - January 19, 2016 Category: Journals (General) Authors: Laiwalla, A. N., Ooi, Y. C., Van De Wiele, B., Ziv, K., Brown, A., Liou, R., Saver, J. L., Gonzalez, N. R. Tags: Open access, Anaesthesia, Evidence based practice, Surgery Research Source Type: research
To intervene or not? A man with multidrug-resistant hypertension, endovascular abdominal aneurysm repair, bilateral renal artery stenosis and end-stage renal disease salvaged with renal artery stenting.
We report the case of a 69-year-old man with uncontrolled multidrug-resistant secondary hypertension following a 10 year history of endovascular abdominal aortic aneurysm repair, with suprarenal fixation and concurrent angioplasty with stenting of the left renal artery for atherosclerotic renal disease, and progressive chronic kidney disease. Renal scintigraphy revealed complete loss of the right kidney's and severe reduction of the left kidney's perfusion and function. Following recent evidence and consultation with vascular surgeons regarding the technical difficulties of any procedure, escalation of antihypertensive tre...
Source: Blood Pressure - February 14, 2016 Category: Hematology Tags: Blood Press Source Type: research
Winter metabolic depression does not change arterial baroreflex control of heart rate in the tegu lizard Salvator merianae RESEARCH ARTICLE
Lucas A. Zena, Valter Dantonio, Luciane H. Gargaglioni, Denis V. Andrade, Augusto S. Abe, and Kenia C. Bicego
Baroreflex regulation of blood pressure is important for maintaining appropriate tissue perfusion. Although temperature affects heart rate (fH) reflex regulation in some reptiles and toads, no data are available on the influence of temperature-independent metabolic states on baroreflex. The South American tegu lizard Salvator merianae exhibits a clear seasonal cycle of activity decreasing fH along with winter metabolic downregulation, independent of body temperature. Through pharmacological interventions (phenyleph...
Source: Journal of Experimental Biology - March 2, 2016 Category: Biology Authors: Zena, L. A., Dantonio, V., Gargaglioni, L. H., Andrade, D. V., Abe, A. S., Bicego, K. C. Tags: RESEARCH ARTICLE Source Type: research
A new variation of dual left anterior descending coronary artery
We report a new variation of dual LAD which has not been reported previously and coronary computed tomography angiography helped to characterize this anomaly. Our case further expands anatomical variations of dual LADs.>
Source: Journal of Cardiology Cases - March 30, 2016 Category: Cardiology Source Type: research
O-013 Hypertension Decreases the Number and Duration of Collateral Openings during Middle Cerebral Artery Occlusion (MCAO) and Impairs Reperfusion
ConclusionsThese results demonstrate that collateral flow during ischemia, and reperfusion, was impaired in hypertension likely due to vasoconstriction of LMAs. Understanding the function of pial collaterals under conditions such as hypertension, that is associated with little penumbral tissue, may provide targeted therapies to prevent collateral failure and extend the time window for treatment in these patients.DisclosuresM. Cipolla: 1; C; NIH grants. J. Sweet: None. K. Chan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Cipolla, M., Sweet, J., Chan, K. Tags: Oral abstracts Source Type: research
Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study
Publication date: Available online 30 August 2016 Source:The Lancet Author(s): Emmanuelle Vidal-Petiot, Ian Ford, Nicola Greenlaw, Roberto Ferrari, Kim M Fox, Jean-Claude Tardif, Michal Tendera, Luigi Tavazzi, Deepak L Bhatt, Philippe Gabriel Steg Background The optimum blood pressure target in hypertension remains debated, especially in coronary artery disease, given concerns for reduced myocardial perfusion if diastolic blood pressure is too low. We aimed to study the association between achieved blood pressure and cardiovascular outcomes in patients with coronary artery disease and hypertension. Methods We analysed dat...
Source: The Lancet - August 30, 2016 Category: Journals (General) Source Type: research
CT perfusion in predicting the morbidity and prognosis of hypoxic-ischemic encephalopathy after off-pump coronary artery bypass grafting.
CONCLUSION: The difference in occipital lobe rTTP on CTA perfusion may be a potential predictor of HIE. Furthermore, abnormal CT and rTTP may be used for predicting the prognosis in HIE patients. Three principal components (F1 as a reflection of CBF, F2 as reflection of TTP, F3 as a reflection of MTT) can be used to generally describe perfusion parameters.
PMID: 28454490 [PubMed - as supplied by publisher]
Source: Neurological Research - May 1, 2017 Category: Neurology Tags: Neurol Res Source Type: research
Pulmonary hypertension and right heart failure due to severe hypernatremic dehydration.
CONCLUSION: A high index of suspicion is paramount to diagnose pulmonary hypertension and aggressive correction of the acidosis and hypoxia is needed. In the presence of severe right ventricular failure, ECMO can be used as a bridge to recovery while underlying metabolic derangements are being corrected.
PMID: 28553778 [PubMed - in process]
Source: Perfusion - May 30, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Chiwane S, Ahmed TM, Bauerfeld CP, Chauhan M Tags: Perfusion Source Type: research
Clinical and radiological assessment of cerebral hemodynamics after cranioplasty for decompressive craniectomy – A Clinical study
Conclusion Cranioplasty influences the cerebral hemodynamics after cranioplasty and has a positive correlation on the functional outcome and cerebral blood flow in the MCA territory.
Source: Journal of Clinical Neuroscience - June 29, 2017 Category: Neuroscience Source Type: research
Abstract 031: Diastolic Blood Pressure, Coronary Artery Calcium, and Cardiac Outcomes in the Multi-ethnic Study of Atherosclerosis Session Title: Cardiac Hypertrophy and Dysfunction
Diastolic blood pressure (BP) has a J-curve relationship with coronary heart disease and death. Because this association is thought to reflect reduced coronary perfusion at low diastolic BP, our objective was to test whether the J-curve is most pronounced among persons with coronary artery calcium. Among 6,811 participants from the Multi-Ethnic Study of Atherosclerosis, we used Cox models to examine if diastolic BP category is associated with coronary heart disease events, stroke, and mortality. Analyses were conducted in the sample overall and after stratification by coronary artery calcium score. In multivariable-adjuste...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: John W McEvoy, Faisal Rahman, Mahmoud Al Rifai, Michael Blaha, Khurram Nasir, Matthew Budoff, Bruce Psaty, Wendy Post, Roger Blumenthal Tags: Oral Abstract Presentations Source Type: research
