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Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Effect of Collateral Blood Flow on Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke Clinical Sciences
Conclusions— Collaterals correlate with baseline National Institutes of Health Stroke Scale, perfusion-weighted imaging volume, and good reperfusion. However, target mismatch patients who reperfuse seem to have favorable outcomes at a similar rate, irrespective of the collateral score. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01349946.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Marks, M. P., Lansberg, M. G., Mlynash, M., Olivot, J.-M., Straka, M., Kemp, S., McTaggart, R., Inoue, M., Zaharchuk, G., Bammer, R., Albers, G. W., for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 (DEFUSE 2) Investigato Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Angiography, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Performed in Acute Perinatal Stroke Reveals Hyperperfusion Associated With Ischemic Injury Clinical Sciences
Conclusions— Perfusion-weighted imaging can be obtained in neonates with acute stroke and often reveals hyperperfusion in the infarct core. Penumbra in arterial ischemic stroke is seldom found. Hyperperfusion may be caused by poststroke reperfusion or to neuronal hyperexcitability of stroke-associated seizure. Its identification may be useful for consideration of therapy for acute neonatal stroke.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Watson, C. G., Dehaes, M., Gagoski, B. A., Grant, P. E., Rivkin, M. J. Tags: Pediatrics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Early Insulin Glycemic Control Combined With tPA Thrombolysis Reduces Acute Brain Tissue Damages in a Focal Embolic Stroke Model of Diabetic Rats Brief Reports
Conclusions— Early insulin glycemic control may be beneficial in combination with tPA thrombolysis for ischemic stroke with diabetes mellitus or poststroke hyperglycemia.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Fan, X., Ning, M., Lo, E. H., Wang, X. Tags: Animal models of human disease, Type 1 diabetes, Acute Cerebral Infarction, Embolic stroke, Emergency treatment of Stroke, Thrombolysis Brief Reports Source Type: research

Utility of Computed Tomographic Perfusion in Thrombolysis for Minor Stroke Brief Reports
Conclusions— In selected MIS patients with demonstrable penumbra on computed tomographic perfusion, IV-tPA is safe and associated with significant improvement in functional outcome at discharge and 90 days.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Ng, F. C., Coote, S., Frost, T., Bladin, C., Choi, P. M. Tags: Computerized Tomography (CT), Diagnostic Testing, Treatment, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Remote Ischemic Perconditioning as an Adjunct Therapy to Thrombolysis in Patients With Acute Ischemic Stroke: A Randomized Trial Clinical Sciences
Conclusions— Although the overall results were neutral, a tissue survival analysis suggests that prehospital rPerC may have immediate neuroprotective effects. Future clinical trials should take such immediate effects, and their duration, into account. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00975962.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Hougaard, K. D., Hjort, N., Zeidler, D., Sorensen, L., Norgaard, A., Hansen, T. M., von Weitzel-Mudersbach, P., Simonsen, C. Z., Damgaard, D., Gottrup, H., Svendsen, K., Rasmussen, P. V., Ribe, L. R., Mikkelsen, I. K., Nagenthiraja, K., Cho, T.-H., Reding Tags: Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Neuroprotectors, Thrombolysis Clinical Sciences Source Type: research

Acute stroke imaging: recent updates.
Authors: Dubey P, Pandey S, Moonis G Abstract Acute ischemic stroke imaging is one of the leading causes of death and disability worldwide. Neuroimaging plays a crucial role in early diagnosis and yields essential information regarding tissue integrity, a factor that remains a key therapeutic determinant. Given the widespread public health implications of stroke and central role of neuroimaging in overall management, acute stroke imaging remains a heavily debated, extensively researched, and rapidly evolving subject. There has been recent debate in the scientific community due to divided opinions on the use of CT p...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Cortical Venous Filling on Dynamic Computed Tomographic Angiography: A Novel Predictor of Clinical Outcome in Patients With Acute Middle Cerebral Artery Stroke Clinical Sciences
Conclusions— The combination of extent and velocity of optimal CVF, as assessed with dynamic CT angiography, is useful to identify patients with acute middle cerebral artery stroke at higher risk of poor clinical outcome at 3-month follow-up. Clinical Trial Registration— URL: http://www.trialregister.nl/trialreg and http://www.clinicaltrials.gov. Unique identifier: NTR1804 and NCT00880113, respectively.
Source: Stroke - February 22, 2016 Category: Neurology Authors: van den Wijngaard, I. R., Wermer, M. J. H., Boiten, J., Algra, A., Holswilder, G., Meijer, F. J. A., Dippel, D. W. J., Velthuis, B. K., Majoie, C. B. L. M., van Walderveen, M. A. A. Tags: Computerized Tomography (CT), Imaging, Prognosis, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Prediction of Stroke Onset Is Improved by Relative Fluid-Attenuated Inversion Recovery and Perfusion Imaging Compared to the Visual Diffusion-Weighted Imaging/Fluid-Attenuated Inversion Recovery Mismatch Clinical Sciences
Conclusions— In patients with unknown stroke onset, the accuracy of predicting time from symptom onset within 4.5 hours is improved by obtaining relative FLAIR and perfusion imaging.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Wouters, A., Dupont, P., Norrving, B., Laage, R., Thomalla, G., Albers, G. W., Thijs, V., Lemmens, R. Tags: Magnetic Resonance Imaging (MRI), Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Agreement Among Stroke Faculty and Fellows in Treating Ischemic Stroke Patients With Tissue-Type Plasminogen Activator and Thrombectomy Brief Report
Conclusions—We found substantial agreement between vascular neurology fellows and faculty in treating with tissue-type plasminogen activator or IAT. Areas for improvement include recognition of stroke mimics, consensus on treating less severe strokes, and use/interpretation of imaging.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Ahmad-Riad Ramadan, Mary Carter Denny, Farhaan Vahidy, Jose-Miguel Yamal, Tzu-Ching Wu, Amrou Sarraj, Sean Savitz, James Grotta Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Prevalence of Imaging Biomarkers to Guide the Planning of Acute Stroke Reperfusion Trials Brief Report
Conclusions—As part of the feasibility analysis in stroke clinical trials, this analysis and the resulting tables can help investigators determine sample size and the number needed to screen.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Bin Jiang, Robyn L. Ball, Patrik Michel, Tudor Jovin, Manisha Desai, Ashraf Eskandari, Zack Naqvi, Max Wintermark Tags: Computerized Tomography (CT), Ischemic Stroke Brief Reports Source Type: research

Alberta Stroke Program Early CT Scale Evaluation of Multimodal Computed Tomography in Predicting Clinical Outcomes of Stroke Patients Treated With Aspiration Thrombectomy Clinical Sciences
Conclusions— CT perfusion parameters, evaluated with ASPECTS, are optimal predictors of outcome and are more sensitive and specific than CT ASPECTS in the prediction of favorable outcome. Use of these parameters in treatment decisions could reduce futile recanalizations.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Psychogios, M.-N., Schramm, P., Frolich, A. M., Kallenberg, K., Wasser, K., Reinhardt, L., Kreusch, A. S., Jung, K., Knauth, M. Tags: CT and MRI, Other diagnostic testing, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Systematic Review, Critical Appraisal, and Analysis of the Quality of Economic Evaluations in Stroke Imaging Clinical Sciences
Conclusions— Economic evaluations of imaging modalities after acute ischemic stroke were generally of high methodological quality. However, important radiology-specific clinical components were missing from all of these analyses.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Burton, K. R., Perlis, N., Aviv, R. I., Moody, A. R., Kapral, M. K., Krahn, M. D., Laupacis, A. Tags: CT and MRI, Acute Stroke Syndromes, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Sensitivity of Diffusion- and Perfusion-Weighted Imaging for Diagnosing Acute Ischemic Stroke Is 97.5% Clinical Sciences
Conclusions— The combination of DWI and PWI before intravenous tissue-type plasminogen activator confirms the diagnosis in 97.5% of all ischemic strokes.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Simonsen, C. Z., Madsen, M. H., Schmitz, M. L., Mikkelsen, I. K., Fisher, M., Andersen, G. Tags: Imaging, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Time-Dependent Computed Tomographic Perfusion Thresholds for Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions— Optimal CTP thresholds associated with follow-up infarction depend on time from imaging to reperfusion.
Source: Stroke - November 23, 2015 Category: Neurology Authors: d'Esterre, C. D., Boesen, M. E., Ahn, S. H., Pordeli, P., Najm, M., Minhas, P., Davari, P., Fainardi, E., Rubiera, M., Khaw, A. V., Zini, A., Frayne, R., Hill, M. D., Demchuk, A. M., Sajobi, T. T., Forkert, N. D., Goyal, M., Lee, T. Y., Menon, B. K. Tags: Computerized Tomography (CT), Imaging, Ischemic Stroke Clinical Sciences Source Type: research

Neurorestorative Responses to Delayed Human Mesenchymal Stromal Cells Treatment of Stroke in Type 2 Diabetic Rats Basic Sciences
Conclusions—In T2DM stroke rats, delayed hMSC treatment significantly improves neurological functional outcome and increases neurorestorative effects and M2 macrophage polarization. Increasing brain platelet-derived growth factor expression may contribute to hMSC-induced neurorestoration.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Yan, T., Venkat, P., Chopp, M., Zacharek, A., Ning, R., Roberts, C., Zhang, Y., Lu, M., Chen, J. Tags: Cell Therapy, Stem Cells, Diabetes, Type 2, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research