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Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Inhibition of CD147 (Cluster of Differentiation 147) Ameliorates Acute Ischemic Stroke in Mice by Reducing Thromboinflammation Basic Sciences
Conclusions—Inhibition of CD147 ameliorates acute ischemic stroke by reducing thromboinflammation. CD147 might represent a novel and promising therapeutic target for ischemic stroke and possibly other thromboinflammatory disorders.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Rui Chen, D. Neil Granger, Guohong Li Tags: Basic Science Research, Ischemic Stroke Original Contributions Source Type: research

Perfusion MR Predicts Outcome in High-Risk Transient Ischemic Attack/Minor Stroke: A Derivation-Validation Study Clinical Sciences
Conclusions— Among subjects with high-risk transient ischemic attack and minor stroke, diffusion-weighted imaging–perfusion-weighted imaging mismatch predicts infarct growth and clinical deterioration. These findings suggest that reperfusion strategies would be beneficial in this population.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Asdaghi, N., Hill, M. D., Coulter, J. I., Butcher, K. S., Modi, J., Qazi, A., Goyal, M., Demchuk, A. M., Coutts, S. B. Tags: CT and MRI, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection Basic Sciences
Conclusions— Induction of lymphocytopenia and concomitant reduction of microvascular thrombosis are key modes of FTY720 action in stroke. In contrast, our findings in Rag1–/– mice and cultured neurons argue against direct neuroprotective effects of FTY720.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Kraft, P., Gob, E., Schuhmann, M. K., Gobel, K., Deppermann, C., Thielmann, I., Herrmann, A. M., Lorenz, K., Brede, M., Stoll, G., Meuth, S. G., Nieswandt, B., Pfeilschifter, W., Kleinschnitz, C. Tags: Animal models of human disease, Ischemic biology - basic studies, Acute Cerebral Infarction, Pathology of Stroke, Anticoagulants Basic Sciences Source Type: research

Diffusion-Weighted Image and Fluid-Attenuated Inversion Recovery Image Mismatch: Unclear-Onset Versus Clear-Onset Stroke Clinical Sciences
Conclusions— The proportion of DWI–FLAIR mismatch in UnCOS within the first 2 hours from first-found abnormal time was similar with COS, but it sharply decreased beyond 2 hours. These data suggest that patients with UnCOS within 2 hours of symptom detection may be good candidates for multimodal imaging-based thrombolysis.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Kim, B. J., Kim, H.-J., Lee, D. H., Kwon, S. U., Kim, S. J., Kim, J. S., Kang, D.-W. Tags: Cerebrovascular disease/stroke, CT and MRI Clinical Sciences Source Type: research

Computed Tomographic Angiography and Cerebral Blood Volume Can Predict Final Infarct Volume and Outcome After Recanalization Clinical Sciences
Conclusions— CTASI and CBV were better at predicting 24-hour infarct and outcome than NECT. Appropriate advanced imaged guided selection may improve outcomes in large-vessel stroke treated with the newest techniques.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Lum, C., Ahmed, M. E., Patro, S., Thornhill, R., Hogan, M., Iancu, D., Lesiuk, H., dos Santos, M., Dowlatshahi, D., on behalf of the Ottawa Stroke Research Group (OSRG) Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Angioplasty and Stenting Clinical Sciences Source Type: research

Immediate Changes in Stroke Lesion Volumes Post Thrombolysis Predict Clinical Outcome Clinical Sciences
Conclusions— Reversal of the DWI volume at 24 hours because of immediate reperfusion in patients post thrombolysis is predictive of favorable clinical outcome.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Luby, M., Warach, S. J., Nadareishvili, Z., Merino, J. G. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke, Thrombolysis Clinical Sciences Source Type: research

How Sustained Is 24-Hour Diffusion-Weighted Imaging Lesion Reversal?: Serial Magnetic Resonance Imaging in a Patient Cohort Thrombolyzed Within 4.5 Hours of Stroke Onset Clinical Sciences
Conclusions— After thrombolysis, over two-thirds of the DWI lesion reversal captured on 24-hour follow-up MR is sustained. Sustained DWI lesion reversal volume is a strong imaging correlate of early neurological improvement.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Soize, S., Tisserand, M., Charron, S., Turc, G., Ben Hassen, W., Labeyrie, M.-A., Legrand, L., Mas, J.-L., Pierot, L., Meder, J.-F., Baron, J.-C., Oppenheim, C. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Time-Resolved C-Arm Computed Tomographic Angiography Derived From Computed Tomographic Perfusion Acquisition: New Capability for One-Stop-Shop Acute Ischemic Stroke Treatment in the Angiosuite Clinical Sciences
Conclusions— Time-resolved CTAs derived from C-arm CT perfusion acquisitions provide high quality images that allowed accurate diagnosis of large vessel occlusions. Although image quality of smaller arteries in this study was not optimal ongoing modifications of the postprocessing algorithm will likely remove this limitation. Adding time-resolved C-arm CTAs to the capabilities of the angiography suite further enhances its suitability as a one-stop shop for care for patients with acute ischemic stroke.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Yang, P., Niu, K., Wu, Y., Struffert, T., Dorfler, A., Schafer, S., Royalty, K., Strother, C., Chen, G.-H. Tags: Angiography, Diagnostic Testing, Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Impact of Collateral Status Evaluated by Dynamic Computed Tomographic Angiography on Clinical Outcome in Patients With Ischemic Stroke Clinical Sciences
Conclusions— Collateral assessment with dynamic CTA better predicts clinical outcome at 3 months than single-phase conventional CTA. Clinical Trial Registration— URL: http://www.trialregister.nl/trialreg. Unique identifier: NTR1804. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00880113.
Source: Stroke - November 23, 2015 Category: Neurology Authors: van den Wijngaard, I. R., Boiten, J., Holswilder, G., Algra, A., Dippel, D. W. J., Velthuis, B. K., Wermer, M. J. H., van Walderveen, M. A. A. Tags: Computerized Tomography (CT), Imaging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Relationship Between Collateral Status, Contrast Transit, and Contrast Density in Acute Ischemic Stroke Clinical Sciences
Conclusions— Visual collateral status, contrast peak density, and contrast peak time delay were inter-related, and good collateral status was strongly associated with contrast peak density. Contrast peak density in collateral vessel may be an important factor in tissue fate in acute ischemic stroke.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Kawano, H., Bivard, A., Lin, L., Spratt, N. J., Miteff, F., Parsons, M. W., Levi, C. R. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Association Between Time From Stroke Onset and Fluid-Attenuated Inversion Recovery Lesion Intensity Is Modified by Status of Collateral Circulation Clinical Sciences
Conclusions— Our findings show that the relationship between time from symptom onset and rFLAIR lesion intensity depends on collateral status. In patients with good collaterals, the development of an rFLAIR-positive lesion is less dependent on time from symptom onset compared with patients with poor collaterals.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wouters, A., Dupont, P., Christensen, S., Norrving, B., Laage, R., Thomalla, G., Albers, G., Thijs, V., Lemmens, R. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

ASPECTS (Alberta Stroke Program Early CT Score) Assessment of the Perfusion-Diffusion Mismatch Clinical Sciences
Conclusions— The mismatch-ASPECTS method can detect a true mismatch in patients with acute middle cerebral artery stroke. It could be used for rapid screening of patients with eligible mismatch, in centers not equipped with ultrafast postprocessing software.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Lassalle, L., Turc, G., Tisserand, M., Charron, S., Roca, P., Lion, S., Legrand, L., Edjlali, M., Naggara, O., Meder, J.-F., Mas, J.-L., Baron, J.-C., Oppenheim, C. Tags: Magnetic Resonance Imaging (MRI), Revascularization, Ischemic Stroke Clinical Sciences Source Type: research

Smoking-Thrombolysis Paradox: Recanalization and Reperfusion Rates After Intravenous Tissue Plasminogen Activator in Smokers With Ischemic Stroke Original Contributions
Conclusions— Smoking is independently associated with recanalization and reperfusion, indicating that thrombolytic therapy acts more effectively in smokers; because of small numbers, these results should be considered preliminary. Clinical Trial Registration— URL: http://clinicaltrials.gov. Unique Identifier: NCT00715533.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Kufner, A., Nolte, C. H., Galinovic, I., Brunecker, P., Kufner, G. M., Endres, M., Fiebach, J. B., Ebinger, M. Tags: Fibrinolysis, Angiography, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research

Favorable Vascular Profile is an Independent Predictor of Outcome: A Post Hoc Analysis of the Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke Trial Clinical Sciences
Conclusions— FVP and baseline NIHSS independently predicted outcome in this subset of the SENTIS population. FVP is a novel parameter to predict outcome of acute stroke patients and further studies will establish its potential role for selection of optimal candidates for hemodynamic augmentation. Clinical Trial Registration Information— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00119717
Source: Stroke - May 24, 2013 Category: Neurology Authors: Schellinger, P. D., Kohrmann, M., Liu, S., Dillon, W. P., Nogueira, R. G., Shuaib, A., Liebeskind, D. S., for the SENTIS Trial Investigators Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Comparison of Magnetic Resonance Imaging Mismatch Criteria to Select Patients for Endovascular Stroke Therapy Clinical Sciences
Conclusions— The MRA–DWI mismatch is a promising alternative to DEFUSE 2’s PWI–DWI mismatch for patient selection in endovascular stroke trials.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Mishra, N. K., Albers, G. W., Christensen, S., Marks, M., Hamilton, S., Straka, M., Liggins, J. T. P., Kemp, S., Mlynash, M., Bammer, R., Lansberg, M. G., for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 Investigators Tags: Angiography, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research