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Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Value of Computed Tomographic Perfusion-Based Patient Selection for Intra-Arterial Acute Ischemic Stroke Treatment Clinical Sciences
Conclusions— CTP seems useful for predicting functional outcome, but cannot reliably identify patients who will not benefit from intra-arterial therapy.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Borst, J., Berkhemer, O. A., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., van Walderveen, M. A. A., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Yoo, A. J., Marquering, H. A., Majoie, C. B. L. M., on behalf of the Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Computerized Tomography (CT), Treatment, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research

Automated CT Perfusion Ischemic Core Volume and Noncontrast CT ASPECTS (Alberta Stroke Program Early CT Score): Correlation and Clinical Outcome Prediction in Large Vessel Stroke Clinical Sciences
Conclusions— There is wide variability of CTP-derived core volumes within ASPECTS strata. Patient selection may be affected by the imaging selection method.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Haussen, D. C., Dehkharghani, S., Rangaraju, S., Rebello, L. C., Bouslama, M., Grossberg, J. A., Anderson, A., Belagaje, S., Frankel, M., Nogueira, R. G. Tags: Imaging, Revascularization, Ischemic Stroke Clinical Sciences Source Type: research

Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling Clinical Sciences
Background and Purpose—Perfusion-weighted imaging is used to select patients with acute ischemic stroke for intervention, but knowledge of cerebral perfusion can also inform the understanding of ischemic injury. Arterial spin labeling allows repeated measurement of absolute cerebral blood flow (CBF) without the need for exogenous contrast. The aim of this study was to explore the relationship between dynamic CBF and tissue outcome in the month after stroke onset.Methods—Patients with nonlacunar ischemic stroke underwent ≤5 repeated magnetic resonance imaging scans at presentation, 2 hours, 1 day, 1 week, and 1 month....
Source: Stroke - December 22, 2016 Category: Neurology Authors: George W.J. Harston, Thomas W. Okell, Fintan Sheerin, Ursula Schulz, Phil Mathieson, Ian Reckless, Kunal Shah, Gary A. Ford, Michael A. Chappell, Peter Jezzard, James Kennedy Tags: Ischemic Stroke Original Contributions Source Type: research

Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke Clinical Sciences
Background and Purpose—Within different brain regions, we determine the comparative value of multiphase computed tomographic angiography (mCTA) and computed tomographic perfusion (CTP) in predicting follow-up infarction.Methods—Patients with M1-middle cerebral artery occlusions were prospectively included in this multicenter study. Regional analysis was performed for each patient within Alberta Stroke Program Early CT Score regions M2 to M6. Regional pial vessel filling was assessed on mCTA in 3 ways: (1) Washout of contrast within pial vessels; (2) Extent of maximal pial vessel enhancement compared with contralateral ...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Christopher D. d’Esterre, Anurag Trivedi, Pooneh Pordeli, Mari Boesen, Shivanand Patil, Seong Hwan Ahn, Mohamed Naȷm, Enrico Fainardi, Jai Jai Shiva Shankar, Marta Rubiera, Mohammed A. Almekhlafi, Jennifer Mandzia, Alexander V. Khaw, Philip Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research

Efficacy of Stent-Retriever Thrombectomy in Magnetic Resonance Imaging Versus Computed Tomographic Perfusion-Selected Patients in SWIFT PRIME Trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke) Clinical Sciences
Conclusions—Time to randomization was significantly longer in MRI-selected patients; however, site arrival to randomization times were not prolonged, and the benefits of endovascular therapy were similar.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01657461.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Nicolas Menjot de Champfleur, Jeffrey L. Saver, Mayank Goyal, Reza Jahan, Hans-Christoph Diener, Alain Bonafe, Elad I. Levy, Vitor M. Pereira, Christophe Cognard, Dileep R. Yavagal, Gregory W. Albers Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Revascularization, Ischemic Stroke Original Contributions Source Type: research

Prediction of Clinical Outcome After Acute Ischemic Stroke Brief Report
Conclusions—Follow-up imaging after 3 days improves outcome prediction compared with prediction based on baseline variables alone. CTA recanalization and CTP reperfusion do not outperform noncontrast CT at this time point.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00880113.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Jan W. Dankbaar, Alexander D. Horsch, Andor F. van den Hoven, L. Jaap Kappelle, Irene C. van der Schaaf, Tom van Seeters, Birgitta K. Velthuis Tags: Computerized Tomography (CT), Prognosis, Ischemic Stroke Brief Reports Source Type: research

Early Imaging Prediction of Malignant Cerebellar Edema Development in Acute Ischemic Stroke Brief Report
Background and Purpose—Malignant cerebellar edema (MCE) is a life-threatening complication of acute ischemic stroke that requires timely diagnosis and management. Aim of this study was to identify imaging predictors in initial multiparametric computed tomography (CT), including whole-brain CT perfusion (WB-CTP).Methods—We consecutively selected all subjects with cerebellar ischemic WB-CTP deficits and follow-up–confirmed cerebellar infarction from an initial cohort of 2635 patients who had undergone multiparametric CT because of suspected stroke. Follow-up imaging was assessed for the presence of MCE, measured using ...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Matthias P. Fabritius, Kolja M. Thierfelder, Felix G. Meinel, Ahmed E. Othman, Franziska Dorn, Bastian O. Sabel, Pierre Scheffler, Birgit Ertl-Wagner, Wieland H. Sommer, Wolfgang G. Kunz Tags: Computerized Tomography (CT), Prognosis, Complications, Mortality/Survival, Ischemic Stroke Brief Reports Source Type: research

Boosted Tree Model Reforms Multimodal Magnetic Resonance Imaging Infarct Prediction in Acute Stroke Clinical Sciences
Background and Purpose—Stroke imaging is pivotal for diagnosis and stratification of patients with acute ischemic stroke to treatment. The potential of combining multimodal information into reliable estimates of outcome learning calls for robust machine learning techniques with high flexibility and accuracy. We applied the novel extreme gradient boosting algorithm for multimodal magnetic resonance imaging–based infarct prediction.Methods—In a retrospective analysis of 195 patients with acute ischemic stroke, fluid-attenuated inversion recovery, diffusion-weighted imaging, and 10 perfusion parameters were derived from...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Michelle Livne, Jens K. Boldsen, Irene K. Mikkelsen, Jochen B. Fiebach, Jan Sobesky, Kim Mouridsen Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Thalamic Diaschisis in Acute Ischemic Stroke Clinical Sciences
Background and Purpose—Ipsilateral thalamic diaschisis (ITD) describes the reduction of thalamic function, metabolism, and perfusion resulting from a distant lesion of the ipsilateral hemisphere. Our aim was to evaluate the perfusion characteristics and clinical impact of ITD in acute middle cerebral artery stroke, which does not directly affect the thalamus.Methods—One hundred twenty-four patients with middle cerebral artery infarction were selected from a prospectively acquired cohort of 1644 patients who underwent multiparametric computed tomography (CT), including CT perfusion for suspected stroke. Two blinded read...
Source: Stroke - March 26, 2018 Category: Neurology Authors: Paul Reidler, Kolja M. Thierfelder, Matthias P. Fabritius, Wieland H. Sommer, Felix G. Meinel, Franziska Dorn, Frank A. Wollenweber, Marco Duering, Wolfgang G. Kunz Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research

Induction of Cooling With a Passive Head and Neck Cooling Device: Effects on Brain Temperature After Stroke Clinical Sciences
Conclusions— Although the decrease of brain temperature after Sovika cooling device application was statistically significant, we doubt clinical relevance of this rather limited effect (–0.36°C). Moreover, the transient increases of blood pressure and ICP warrant caution.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Poli, S., Purrucker, J., Priglinger, M., Diedler, J., Sykora, M., Popp, E., Steiner, T., Veltkamp, R., Bosel, J., Rupp, A., Hacke, W., Hametner, C. Tags: Cerebrovascular disease/stroke, CPR and emergency cardiac care, Other Treatment, Emergency treatment of Stroke Clinical Sciences Source Type: research

Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke Clinical Sciences
This study aimed to derive and validate a predictive model for functional outcome based on acute clinical and advanced imaging measures.Methods—A database of prospectively collected sub-4.5 hour patients with ischemic stroke being assessed for thrombolysis from 5 centers who had computed tomographic perfusion and computed tomographic angiography before a treatment decision was assessed. Individual variable cut points were derived from a classification and regression tree analysis. The optimal cut points for each assessment variable were then used in a backward logic regression to predict modified Rankin scale (mRS) score...
Source: Stroke - February 26, 2017 Category: Neurology Authors: Andrew Bivard, Christopher Levi, Longting Lin, Xin Cheng, Richard Aviv, Neil J. Spratt, Min Lou, Tim Kleinig, Billy O’Brien, Kenneth Butcher, Jingfen Zhang, Jim Jannes, Qiang Dong, Mark Parsons Tags: Clinical Studies, Pathophysiology, Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research

Role of Genetic Variation in Collateral Circulation in the Evolution of Acute Stroke Basic Sciences
We examined ischemic tissue evolution during acute stroke, as measured by magnetic resonance imaging and histology, by comparing 2 congenic mouse strains with otherwise identical genetic backgrounds but with different alleles of the Determinant of collateral extent-1 (Dce1) genetic locus. We also optimized magnetic resonance perfusion and diffusion–deficit thresholds by using histological measures of ischemic tissue.Methods—Perfusion, diffusion, and T2-weighted magnetic resonance imaging were performed on collateral-poor (congenic-Bc) and collateral-rich (congenic-B6) mice at 1, 5, and 24 hours after permanent middle c...
Source: Stroke - February 26, 2017 Category: Neurology Authors: Yu-Chieh Jill Kao, Esteban A. Oyarzabal, Hua Zhang, James E. Faber, Yen-Yu Ian Shih Tags: Genetics, Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Computed Tomographic Perfusion Selection and Clinical Outcomes After Endovascular Therapy in Large Vessel Occlusion Stroke Clinical Sciences
Background and Purpose—Different imaging paradigms have been used to select patients for endovascular therapy in stroke. We sought to determine whether computed tomographic perfusion (CTP) selection improves endovascular therapy outcomes compared with noncontrast computed tomography alone.Methods—Review of a prospectively collected registry of anterior circulation stroke patients undergoing stent-retriever thrombectomy at a tertiary care center between September 2010 and March 2016. Patients undergoing CTP were compared with those with noncontrast computed tomography alone. The primary outcome was the shift in the 90-d...
Source: Stroke - April 24, 2017 Category: Neurology Authors: Mehdi Bouslama, Diogo C. Haussen, Jonathan A. Grossberg, Seena Dehkharghani, Meredith T. Bowen, Leticia C. Rebello, Nicolas A. Bianchi, Michael R. Frankel, Raul G. Nogueira Tags: Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Multiparametric Model for Penumbral Flow Prediction in Acute Stroke Clinical Sciences
In this study, we established a multiparametric perfusion imaging model and cross-validated it using positron emission tomography perfusion for detection of penumbral flow.Methods—In a retrospective analysis of 17 subacute stroke patients with consecutive magnetic resonance imaging and H2O15 positron emission tomography scans, perfusion maps of cerebral blood flow, cerebral blood volume, mean transit time, time-to-maximum, and time-to-peak were constructed and combined using a generalized linear model (GLM). Both the GLM maps and the single perfusion maps alone were cross-validated with positron emission tomography-cereb...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Michelle Livne, Tabea Kossen, Vince I. Madai, Olivier Zaro-Weber, Walter Moeller-Hartmann, Kim Mouridsen, Wolf-Dieter Heiss, Jan Sobesky Tags: Imaging, Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Contributions Source Type: research

Permeability Surface of Deep Middle Cerebral Artery Territory on Computed Tomographic Perfusion Predicts Hemorrhagic Transformation After Stroke Clinical Sciences
Conclusions—Increased PS can predict HT of deep MCA territory after recanalization therapy for cerebral proximal large-vessel occlusion. Proximal MCA-M1 complete occlusion and distal internal carotid artery occlusion in conjunction with poor collaterals elevate deep MCA territory PS.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Qiao Li, Xinyi Gao, Zhenwei Yao, Xiaoyuan Feng, Huijin He, Jing Xue, Peiyi Gao, Lumeng Yang, Xin Cheng, Weijian Chen, Yunjun Yang Tags: Angiography, Computerized Tomography (CT), Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research