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Condition: Hypertension
Procedure: Perfusion
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Total 203 results found since Jan 2013.
Intensive Blood Pressure–Lowering Treatment in Patients with Acute Lacunar Infarction
Conclusions: Considerable reduction in 24-hour BP levels was attained around day 21. The limit of BP level to which BP can be safely lowered appears to be lower than that was previously considered.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2012 Category: Neurology Authors: Yasumasa Yamamoto, Yoshinari Nagakane, Tomoyuki Ohara, Eijiro Tanaka, Fukiko Morii, Takashi Koizumi, Manabu Muranishi, Hidesato Takezawa Tags: Original Articles Source Type: research
Evaluation and Management of the Child With Suspected Acute Stroke
Pediatric stroke occurs at an incidence of 1.6 to 13/100 000 and may be acute ischemic, hemorrhagic, or of sinus venous thrombosis etiology. As these children present to the emergency department, early consideration for this diagnosis is paramount in beginning medical management to optimize cerebral perfusion and minimize secondary injury. There are many identified risk factors in pediatric stroke including arteriopathies, cardiac disease (specifically congenital heart disease), and infection. Modifiable adult risk factors including hypertension, hyperlipidemia, and diabetes are rarely seen in pediatrics.
Source: Clinical Pediatric Emergency Medicine - February 4, 2015 Category: Emergency Medicine Authors: Lindsey Morgan Source Type: research
Risk Factors for Blood-Brain Barrier Disruption in Patients with Chronic Cerebrovascular Disease Presenting with Acute Stroke (P2.245)
Conclusions: These findings suggest that cWMD caused by chronic hypertension may have a different underlying pathophysiology than cWMD that is associated with aging.Disclosure: Dr. Gupta has nothing to disclose. Dr. Luby has nothing to disclose. Dr. Nadareishvili has nothing to disclose. Dr. Benson has nothing to disclose. Dr. Hsia has nothing to disclose. Dr. Lynch has nothing to disclose. Dr. Leigh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gupta, N., Luby, M., Nadareishvili, Z., Benson, R., Hsia, A., Lynch, J., Leigh, R. Tags: Aging and Dementia: Other Source Type: research
Pontine Warning Syndrome: A Chameleon of Ischemic Stroke
Conclusions: PWS is a diagnostic and management challenge for the clinician. Because of its low incidence, this syndrome has been underestimated and understudied. There is, currently, no standard treatment for this condition; however, it is paramount, during treatment, that hypotension/hypoperfusion be avoided, with the goal being asymptomatic normotension to permissive hypertension. The probable mechanism of disease is hypoperfusion due to basilar artery branch disease and perhaps cerebral vascular dysregulation in the affected area.
Source: The Neurologist - November 1, 2016 Category: Neurology Tags: Case Report/Case Series Source Type: research
The effect of superoxide dismutase (SOD) enzyme inhibition on renal microcirculation of spontaneously hypertensive-stroke prone (SHRSP) and Wistar rats.
This study therefore investigated the role of superoxide dismutase (SOD) in the regulation of renal medullary and cortical blood perfusion (MBP and CBP respectively) in both stroke-prone spontaneously hypertensive rats (SHRSP) and normotensive Wistar rats. CBP and MBP were measured before and after intra-renal infusion of the SOD inhibitor, diethyldithio-carbamic acid (DETC). Under basal conditions, mean arterial pressure was significantly greater in SHRSP than Wistar rats, but both MBP and heart rate (HR) were significantly lower in SHRSP relative to Wistar rats (P < 0.05, n=7 in both groups). Infusion of DETC (2 mg/kg...
Source: Physiological Research - May 10, 2018 Category: Physiology Authors: Ahmeda AF, Rae MG, Anweigi LM, Al Otaibi MF, Al-Masri AA, Johns EJ Tags: Physiol Res Source Type: research
Modeling Superimposed Preeclampsia Using Ang II (Angiotensin II) Infusion in Pregnant Stroke-Prone Spontaneously Hypertensive RatsNovelty and Significance Preeclampsia
Hypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Superimposed preeclampsia is an increasingly common problem and often associated with impaired placental perfusion. Understanding the underlying mechanisms and developing treatment options are crucial. The pregnant stroke-prone spontaneously hypertensive rat has impaired uteroplacental blood flow and abnormal uterine artery remodeling. We used Ang II (angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats to mimic the increased cardiovascular stress associated with superimposed preeclampsia and examine ...
Source: Hypertension - June 13, 2018 Category: Cardiology Authors: Hannah L. Morgan, Elaine Butler, Shona Ritchie, Florian Herse, Ralf Dechend, Elisabeth Beattie, Martin W. McBride, Delyth Graham Tags: ACE/Angiotensin Receptors/Renin Angiotensin System, Animal Models of Human Disease, Hypertension, Preeclampsia Original Articles Source Type: research
Blood Pressure Management in Acute Ischemic Stroke
AbstractPurpose of ReviewAbrupt blood pressure (BP) rise is the most common clinical symptom of acute ischemic stroke (AIS). However, BP alterations during AIS reflect many diverse mechanisms, both stroke-related and nonspecific epiphenomena, which change over time and across patients. While extremes of BP as well as high BP variability have been related with worse outcomes in observational studies, optimal BP management after AIS remains challenging.Recent FindingsThis review discusses the complexity of the factors linking BP changes to the clinical outcomes of patients with AIS, depending on the treatment strategy and lo...
Source: Current Hypertension Reports - December 10, 2020 Category: Primary Care Source Type: research
Borderzone Infarction and Small Vessel Disease in a Sample of Egyptian Stroke Patients: Differences and Similarities
Conclusion: Limb shaking, retinal claudication or syncope, with MRI showing rosary pattern of white matter hyperintensity, few microbleeds and markedly impaired perfusion favor the diagnosis of borderzone infarctions. On the other hand, presence of lacunae, FLAIR showing symmetrical WMH and microbleeds with minimal or no perfusion deficit suggests the diagnosis of small vessel disease.
Source: Neurology India - June 24, 2021 Category: Neurology Authors: Nevine M El Nahas Hany M Aref Taha K Alloush Nagia A Fahmy Khaled A Ahmed Ahmed A El Basiouny Mohamed A Tork Ahmed M Elbokl Hossam M Shokri Source Type: research
Posterior Circulation Ischaemic Stroke
Am J Med Sci. 2022 Jan 29:S0002-9629(22)00030-1. doi: 10.1016/j.amjms.2021.10.027. Online ahead of print.ABSTRACTPosterior circulation ischaemic stroke (PCIS) is a disease of high burden. They account for 20-25% of all ischaemic strokes. However, it is relatively under-researched and requires more clinical attention, since it carries worse functional outcomes. Vertigo, visual disturbances and sensory/motor disturbances are found in PCIS. Large artery atherosclerosis and embolism are main causes of PCIS, while there is growing evidence that vertebrobasilar dolichoectasia is a key association. Hypertension is the commonest r...
Source: The American Journal of the Medical Sciences - February 1, 2022 Category: General Medicine Authors: Mr Alexander Ng Source Type: research
Effects of Induced Hypertension on Cerebral Perfusion in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial Brief Reports
Conclusions—
Change in overall CBF did not differ to a statistically significant extent between the groups. Based on our results, 225 to 250 patients per group are needed to find a statistically significant difference in change in overall CBF between induced hypertension and no hypertension.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT0161323.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Gathier, C. S., Dankbaar, J. W., van der Jagt, M., Verweij, B. H., Oldenbeuving, A. W., Rinkel, G. J. E., van den Bergh, W. M., Slooter, A. J. C., for the HIMALAIA Study Group, Algra, Beute, Coert, Dammers, Dippel, Dirven, Horn, Muller, Kesecioglu, van Ko Tags: Clinical Studies, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Computerized tomography and Magnetic Resonance Imaging, Other Stroke Treatment - Medical Brief Reports Source Type: research
Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Before this trial, the effectiveness of induced hypertension for DCI in aneurysmal subarachnoid hemorrhage patients was unknown because current literature consists only of uncontrolled case series. The results from our premature halted trial do not add any evidence to support induced hypertension and show that this treatment can lead to serious adverse events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01613235.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Celine S. Gathier, Walter M. van den Bergh, Mathieu van der Jagt, Bon H. Verweiȷ, Jan Willem Dankbaar, Marcella C. Muller, Annemarie W. Oldenbeuving, Gabriel J.E. Rinkel, Arȷen J.C. Slooter, for the HIMALAIA Study Group* Tags: Treatment, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
A perfusion territory shift attributable solely to the secondary collaterals in moyamoya patients: a potential risk factor for preoperative hemorrhagic stroke revealed by t-ASL and 3D-TOF-MRA.
CONCLUSIONS: t-ASL could reveal comprehensive MMD cerebral blood perfusion and the vivid perfusion territory shifts fed by the unilateral ICA and ECA and bilateral VAs in a noninvasive, straightforward, nonradioactive, and nonenhanced manner. 3D-TOF-MRA could subdivide t-ASL perfusion territory shifts according to their shunt arteries. A perfusion territory shift attributable to the secondary collaterals is a potential independent risk factor for preoperative hemorrhage in MMD patients. A perfusion territory shift fed by the primary collaterals may not have a strong effect on preoperative hemorrhage in MMD patients. These ...
Source: Journal of Neurosurgery - August 8, 2019 Category: Neurosurgery Authors: Gao XY, Li Q, Li JR, Zhou Q, Qu JX, Yao ZW Tags: J Neurosurg Source Type: research
Ipsilateral Vocal Cord Paralysis After Acute Anterior Ischemic Stroke
CONCLUSION: Our case is a rare case of transient ipsilateral vocal cord paralysis associated with anterior unilateral cerebral ischemia. The paralysis resolved with improvement of the cerebral ischemic penumbra.PMID:33635769 | DOI:10.7812/TPP/20.104
Source: The Permanente journal - February 26, 2021 Category: General Medicine Authors: Khalid Sawalha Ahmed Abd Elazim Omar Hussein Source Type: research
