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Source: Hypertension
Condition: Hypertension
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Total 260 results found since Jan 2013.
Abstract 615: Progression Of Atherosclerosis Plaque Area In Postmenopausal Women During Controlled Traditional Risk Factors Poster Session II
Conclusion, these results indicate that in the presence of controlled traditional risk factors, atherosclerosis may progress in some patients, including in menopausal women. Additional promoters of atherosclerosis should be evaluated in these progressive patients or possibly more intensive treatment should be used in such patients.
Source: Hypertension - October 30, 2013 Category: Cardiology Authors: Perez, H. A., Garcia, N. H., Spence, J. D., Armando, L. J. Tags: Poster Session II Source Type: research
Aggressive Blood Pressure Lowering Is Dangerous: The J-Curve: Con Side of the Argument Controversies in Hypertension
Source: Hypertension - December 11, 2013 Category: Cardiology Authors: Verdecchia, P., Angeli, F., Mazzotta, G., Garofoli, M., Reboldi, G. Tags: Cerebrovascular disease/stroke, Other hypertension Controversies in Hypertension Source Type: research
Williams Syndrome Predisposes to Vascular Stiffness Modified by Antihypertensive Use and Copy Number Changes in NCF1 Vascular Stiffness
Williams syndrome is caused by the deletion of 26 to 28 genes, including elastin, on human chromosome 7. Elastin insufficiency leads to the cardiovascular hallmarks of this condition, namely focal stenosis and hypertension. Extrapolation from the Eln+/– mouse suggests that affected people may also have stiff vasculature, a risk factor for stroke, myocardial infarction, and cardiac death. NCF1, one of the variably deleted Williams genes, is a component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex and is involved in the generation of oxidative stress, making it an interesting candidate mod...
Source: Hypertension - December 11, 2013 Category: Cardiology Authors: Kozel, B. A., Danback, J. R., Waxler, J. L., Knutsen, R. H., de las Fuentes, L., Reusz, G. S., Kis, E., Bhatt, A. B., Pober, B. R. Tags: Clinical genetics, Other Vascular biology Vascular Stiffness Source Type: research
Evidence-Based Triple Antihypertensive Therapy Yields Lower Mortality in Older Patients With Diabetes Mellitus Editorial Commentary
Source: Hypertension - January 8, 2014 Category: Cardiology Authors: Yamout, H., Bakris, G. L. Tags: Cerebrovascular disease/stroke, Other hypertension, Clinical Studies Editorial Commentary Source Type: research
Effect of Serum Chloride on Mortality in Hypertensive Patients Letters to the Editor
Source: Hypertension - February 12, 2014 Category: Cardiology Authors: Kawada, T. Tags: Cerebrovascular disease/stroke Letters to the Editor Source Type: research
Tight Versus Standard Blood Pressure Control in Patients With Hypertension With and Without Cardiovascular Disease Heart
In conclusion, an intensive treatment aimed to lower systolic BP<130 mm Hg reduced left ventricular hypertrophy and improved clinical outcomes to a similar extent in patients with hypertension and without established cardiovascular disease.
Source: Hypertension - February 12, 2014 Category: Cardiology Authors: Reboldi, G., Angeli, F., de Simone, G., Staessen, J. A., Verdecchia, P., on behalf of the Cardio-Sis Investigators Tags: Primary prevention, Secondary prevention, Cerebrovascular disease/stroke, Hypertrophy Heart Source Type: research
The Value of N-Terminal Pro-B-Type Natriuretic Peptide in Determining Antihypertensive Benefit: Observations From the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Natriuretic Peptides
We investigated 3 hypotheses: (1) N-terminal pro–B-type natriuretic peptide (NT-proBNP) predicts cardiovascular disease events in patients with hypertension, (2) NT-proBNP is associated with blood pressure variability, and (3) NT-proBNP predicts benefit from antihypertensive regimens. The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) randomized a subset of 6549 patients at risk with no history of coronary heart disease to either atenolol-based or amlodipine-based blood pressure–lowering treatment. During 5.5 years of follow-up, 485 cardiovascular disease cases accrued and were matched with 1367 controls. Ba...
Source: Hypertension - February 12, 2014 Category: Cardiology Authors: Welsh, P., Poulter, N. R., Chang, C. L., Sever, P. S., Sattar, N., on behalf of the ASCOT Investigators Tags: Cerebrovascular disease/stroke Natriuretic Peptides Source Type: research
Natriuretic Peptide: A Probable Culprit in Prevention of Primary Cardiovascular Diseases Using {beta}-Blockers Letters to the Editor
Source: Hypertension - March 12, 2014 Category: Cardiology Authors: Peng, H., Liu, Y. Tags: Biochemistry and metabolism, Cerebrovascular disease/stroke, Myocardial cardiomyopathy disease Letters to the Editor Source Type: research
Prevention of Hypertension and Cardiovascular Diseases: A Comparison of Lifestyle Factors in Westerners and East Asians Brief Reviews
Source: Hypertension - March 12, 2014 Category: Cardiology Authors: Kokubo, Y. Tags: Obesity, Primary prevention, Cerebrovascular disease/stroke, Risk Factors Brief Reviews Source Type: research
Synergistic Effects of High Blood Cholesterol and Hypertension on Leukocyte and Platelet Recruitment in the Cerebral Microcirculation Vessels
In this study, we examined whether larger increments in blood cholesterol (4-fold) exerts a similar modulating influence on the vasculature in the presence of hypertension. Apolipoprotein E–knockout mice with deoxycorticosterone acetate salt–induced hypertension were placed on a high-cholesterol diet and exhibited exaggerated leukocyte and platelet adhesion responses in cerebral microvessels. Intermittent feeding (every fourth day) with high-cholesterol diet yielded similar phenotypic changes in the vasculature. Once the mice were placed on high-cholesterol diet, 4 days on normal diet (ND) were needed to revert...
Source: Hypertension - March 12, 2014 Category: Cardiology Authors: Rodrigues, S. F., Almeida-Paula, L. D., Granger, D. N. Tags: Cerebrovascular disease/stroke Vessels Source Type: research
Is Hypertension Associated With an Accelerated Aging of the Brain? Brief Reviews
Source: Hypertension - April 9, 2014 Category: Cardiology Authors: Tzourio, C., Laurent, S., Debette, S. Tags: Cerebrovascular disease/stroke, Cerebral Lacunes, Epidemiology Brief Reviews Source Type: research
End of the Joint National Committee Heritage? Editorial
Source: Hypertension - April 9, 2014 Category: Cardiology Authors: O'Brien, E. Tags: Health policy and outcome research, Cerebrovascular disease/stroke Editorial Source Type: research
Optimum Blood Pressure Target After Lacunar Stroke: Con Side of the Argument Controversies in Hypertension
Source: Hypertension - April 9, 2014 Category: Cardiology Authors: Schiffrin, E. L. Tags: Other hypertension Controversies in Hypertension Source Type: research
Day-to-Day Variability in Home Blood Pressure Is Associated With Cognitive Decline: The Ohasama Study Blood Pressure Variability and Cognitive Decline
The objectives of this prospective study were to clarify whether home blood pressure has a stronger predictive power for cognitive decline than conventional blood pressure and to compare the predictive power of the averaged home blood pressure with day-to-day home blood pressure variability for cognitive decline. Of 485 participants (mean age, 63 years) who did not have cognitive decline (defined as Mini-Mental State Examination score, <24) initially, 46 developed cognitive decline after a median follow-up of 7.8 years. Each 1-SD increase in the home systolic blood pressure value showed a significant association with co...
Source: Hypertension - May 7, 2014 Category: Cardiology Authors: Matsumoto, A., Satoh, M., Kikuya, M., Ohkubo, T., Hirano, M., Inoue, R., Hashimoto, T., Hara, A., Hirose, T., Obara, T., Metoki, H., Asayama, K., Hosokawa, A., Totsune, K., Hoshi, H., Hosokawa, T., Sato, H., Imai, Y. Tags: Cerebrovascular disease/stroke Blood Pressure Variability and Cognitive Decline Source Type: research
Estrogen Protects Against Intracranial Aneurysm Rupture in Ovariectomized Mice Estrogen and Intracranial Aneurysm Rupture
Clinical observations suggest that postmenopausal women have a higher incidence of aneurysmal rupture than premenopausal women. We hypothesize that a relative deficiency in estrogen may increase the risks of aneurysmal growth and subarachnoid hemorrhage in postmenopausal women. We assessed the effects of estrogen and selective estrogen receptor subtype agonists on the development of aneurysmal rupture in ovariectomized female mice. We used an intracranial aneurysm mouse model that recapitulates the key features of human intracranial aneurysms, including spontaneous rupture. Ten- to 12-week-old ovariectomized female mice re...
Source: Hypertension - May 7, 2014 Category: Cardiology Authors: Tada, Y., Wada, K., Shimada, K., Makino, H., Liang, E. I., Murakami, S., Kudo, M., Shikata, F., Pena Silva, R. A., Kitazato, K. T., Hasan, D. M., Kanematsu, Y., Nagahiro, S., Hashimoto, T. Tags: Animal models of human disease, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Other Stroke Treatment - Medical Estrogen and Intracranial Aneurysm Rupture Source Type: research
