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Condition: Hypothyroidism

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Total 192 results found since Jan 2013.

Post authorization safety study comparing quetiapine to risperidone and olanzapine
ConclusionsQuetiapine was associated with lower EPS, but higher failed suicide attempt rates compared to risperidone. Quetiapine was associated with lower EPS and DM rates compared to olanzapine. The results should be interpreted with caution because of possible channelling and residual confounding. Copyright © 2016 John Wiley & Sons, Ltd.
Source: Human Psychopharmacology: Clinical and Experimental - June 12, 2016 Category: Psychiatry Authors: Edith M. Heintjes, Jetty A. Overbeek, Fernie J. A. Penning‐van Beest, Gunnar Brobert, Ron M. C. Herings Tags: Research Article Source Type: research

What to Expect When Expecting With Systemic Lupus Erythematosus (SLE): A Population‐Based Study of Maternal and Fetal Outcomes in SLE and Pre‐SLE
ConclusionOur data demonstrate that adverse maternal and fetal outcomes are more common in SLE pregnancies. Furthermore, these unfavorable outcomes are observed in pregnancies occurring prior to the diagnosis of SLE. Thus, the underlying immunologic profile of SLE and alterations preceding clinical SLE may contribute to these pregnancy complications.
Source: Arthritis Care and Research - June 22, 2016 Category: Rheumatology Authors: Elizabeth V. Arkema, Kristin Palmsten, Christopher Sjöwall, Elisabet Svenungsson, Jane E. Salmon, Julia F. Simard Tags: Systemic Lupus Erythematosus Source Type: research

Unmasking a Hidden Cause of Persistent Facial Ulceration: The Relevancy of a Neurologic Examination
A 49-year-old woman presented to the Emergency Department of a tertiary medical center for evaluation of chronic facial ulceration. Her past medical history was significant for type II diabetes mellitus, hypothyroidism, antiphospholipid antibody syndrome, venous thromboembolism, and stroke. The patient noted progressive ulceration around the left nasal ala with extension to the left eyebrow and eyelid for 2 years. She had been evaluated for this problem numerous times at outside medical facilities.
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: Kyle W. Mahoney, Jules B. Lipoff, Bennett W. Clark Tags: Diagnostic dilemma Source Type: research

High prevalence of primary dyslipidaemia in black South African patients at a tertiary hospital in northern Gauteng, South Africa.
CONCLUSION: A significant burden and a high prevalence of dyslipidaemias were present in adults in whom a monogenic disorder should be considered. The extent and severity of dyslipidaemia justify a special clinic and laboratory to ensure accurate diagnosis with effective intervention for patients and their families. PMID: 27384370 [PubMed - as supplied by publisher]
Source: South African Medical Journal - July 8, 2016 Category: African Health Tags: S Afr Med J Source Type: research

Clinical outcomes of patients with hypothyroidism undergoing percutaneous coronary intervention
Conclusion Hypothyroidism is associated with a higher incidence of MACCE compared with euthyroidism in patients undergoing PCI. Maintaining adequate control on TRT is beneficial in preventing MACCE.
Source: European Heart Journal - July 10, 2016 Category: Cardiology Authors: Zhang, M., Sara, J. D. S., Matsuzawa, Y., Gharib, H., Bell, M. R., Gulati, R., Lerman, L. O., Lerman, A. Tags: Coronary artery disease Source Type: research

Cognitive Function and the Ageing Process: The Peculiar Role of Mild Thyroid Failure.
Conclusion The available data suggest a complex relationship between mild thyroid failure and the ageing process as well as the development and progression of several cardiovascular and neurological diseases. In this paper, we reviewed the scientific English literature on sHT and the ageing process focusing on experimental evidences related to cognitive impairment and dementia. Moreover, we focused on new patents of treatments potentially able to improve the care of sHT patients, especially in the elderly, where treatment drawbacks may have negative impact on the long term outcome. PMID: 27396589 [PubMed - as supplied by publisher]
Source: Recent Patents on Endocrine, Metabolic and Immune Drug Discovery - July 13, 2016 Category: Endocrinology Tags: Recent Pat Endocr Metab Immune Drug Discov Source Type: research

What to Expect When Expecting With Systemic Lupus Erythematosus (SLE): A Population ‐Based Study of Maternal and Fetal Outcomes in SLE and Pre‐SLE
ConclusionOur data demonstrate that adverse maternal and fetal outcomes are more common in SLE pregnancies. Furthermore, these unfavorable outcomes are observed in pregnancies occurring prior to the diagnosis of SLE. Thus, the underlying immunologic profile of SLE and alterations preceding clinical SLE may contribute to these pregnancy complications.
Source: Arthritis Care and Research - June 22, 2016 Category: Rheumatology Authors: Elizabeth V. Arkema, Kristin Palmsten, Christopher Sj öwall, Elisabet Svenungsson, Jane E. Salmon, Julia F. Simard Tags: Systemic Lupus Erythematosus Source Type: research

Unmasking a Hidden Cause of Persistent Facial Ulceration: The Relevancy of a Neurologic Examination
A 49-year-old woman presented to the Emergency Department of a tertiary medical center for evaluation of chronic facial ulceration. Her past medical history was significant for type II diabetes mellitus, hypothyroidism, antiphospholipid antibody syndrome, venous thromboembolism, and stroke. The patient noted progressive ulceration around the left nasal ala with extension to the left eyebrow and eyelid for 2 years. She had been evaluated for this problem numerous times at outside medical facilities.
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: Kyle W. Mahoney, Jules B. Lipoff, Bennett W. Clark Tags: Diagnostic dilemma Source Type: research

Long-term Outcome in Levothyroxine Treated Patients with Subclinical Hypothyroidism and Concomitant Heart Disease.
CONCLUSION: Levothyroxine treatment in patients with subclinical hypothyroidism and heart disease was not associated with a significant benefit nor risk of all-cause mortality, MACE or hospital admission in this large real-world cohort study. PMID: 27571183 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - August 28, 2016 Category: Endocrinology Authors: Andersen MN, Olsen AS, Madsen JC, Kristensen SL, Faber J, Torp-Pedersen C, Gislason GH, Selmer C Tags: J Clin Endocrinol Metab Source Type: research

I'm a Diabetic, Why is my Shoulder Frozen?
What Is Adhesive Capsulitis? Adhesive capsulitis is a painful, progressive loss of shoulder motion. The shoulder is usually stiff and will not move. This condition is called "frozen shoulder". When a patient presents with adhesive capsulitis, they are unable to move their arm up or turn it to either side either with or without assistance (passive/active range of motion). Typically adhesive capsulitis occurs in approximately 2% of the population and usually affects people 40-60 years of age. Frozen shoulder tends to occur more often in females. The loss of motion occurs due to inflammation, fibrosis, scarring and contractio...
Source: Healthy Living - The Huffington Post - September 6, 2016 Category: Consumer Health News Source Type: news

Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition
ConclusionConcomitant narcotic use and diabetes have a compounding effect on the quality of bowel preparation prior to colonoscopy.
Source: Digestive Diseases and Sciences - December 28, 2016 Category: Gastroenterology Source Type: research

Effects of short ‐term levothyroxine therapy on myocardial injuries in patients with severe overt hypothyroidism: Evidence from a cardiac MRI Study
ConclusionWe suggest that the negative effect induced by severe overt HT on the cardiovascular system can be significantly improved by restoring euthyroidism with short‐term levothyroxine therapy.Level of Evidence: 1J. Magn. Reson. Imaging 2017.
Source: Journal of Magnetic Resonance Imaging - March 21, 2017 Category: Radiology Authors: Xia Gao, Zhe Chen, Min Liu, Yu ‐Mei Jia, Ning Yang, Zhi Yao, Xiao‐Meng Feng, Yuan Xu, Guang Wang Tags: Original Research Source Type: research

Hypothyroidism is associated with all ‐cause mortality in a national cohort of chronic hemodialysis patients
ConclusionHypothyroidism is associated with increased all‐cause mortality in chronic HD patients. The interaction of hypothyroidism and diabetes, but not other common comorbidities in HD patients, has an effect on mortality risks.
Source: Nephrology - March 28, 2017 Category: Urology & Nephrology Authors: Hsuan ‐Jen Lin, Chung‐Chih Lin, Hsuan Ming Lin, Hsuan‐Ju Chen, Che‐Chen Lin, Chiz‐Tzung Chang, Che‐Yi Chou, Chiu‐Ching Huang Tags: Original Article Source Type: research

Pituitary apoplexy causing bilateral anterior cerebral infarction (P3.283)
Conclusions:Pituitary apoplexy occurs when a pituitary tumor, typically macroadenoma, hemorrhages or infarcts resulting in a rapid expansion of the hypophysis and compression of adjacent structures, including the internal carotid arteries (ICA)which can result in cerebral ischemia. Proposed mechanisms of cerebral infarction to date include both direct compression or vasospasm of the ICA. Vasospasm as a cause is proposed to be from either extravasation of blood into the subarachnoid space or release of vasoactive substances by the tumor itself. This matter is still debated in the literature. Emergent recognition and imaging...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Vargas, A., Testai, F. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Association between vitamin D deficiency and heart failure risk in the elderly
ConclusionsThere was a high prevalence of vitamin D deficiency in the elderly, and the evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in this population.
Source: ESC Heart Failure - August 1, 2017 Category: Cardiology Authors: Catarina Magalh ães Porto, Vanessa De Lima Silva, João Soares Brito Luz, Brivaldo Markman Filho, Vera Magalhães Silveira Tags: Original Research Article Source Type: research