Pituitary apoplexy causing bilateral anterior cerebral infarction (P3.283)

Conclusions:Pituitary apoplexy occurs when a pituitary tumor, typically macroadenoma, hemorrhages or infarcts resulting in a rapid expansion of the hypophysis and compression of adjacent structures, including the internal carotid arteries (ICA)which can result in cerebral ischemia. Proposed mechanisms of cerebral infarction to date include both direct compression or vasospasm of the ICA. Vasospasm as a cause is proposed to be from either extravasation of blood into the subarachnoid space or release of vasoactive substances by the tumor itself. This matter is still debated in the literature. Emergent recognition and imaging is imperative to clinical decision making affecting outcome.Disclosure: Dr. Vargas has nothing to disclose. Dr. Testai has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Cerebrovascular Disease Case Reports II Source Type: research