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NIH researchers find potential genetic cause of Cushing syndrome
Finding may lead to therapies that prevent pituitary tumor recurrence. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - June 1, 2017 Category: American Health Source Type: news

Dopamine agonists for pituitary tumours: to treat or not?
The benefits and risks of giving patients medical therapy after surgery to prevent regrowth of nonfunctioning pituitary adenomas was debated at the European Congress of Endocrinology 2017, with the final vote revealing a 50-50 split of opinion from the audience.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 31, 2017 Category: Endocrinology Source Type: news

Dopamine Agonists for Pituitary Tumors: To Treat or Not? Dopamine Agonists for Pituitary Tumors: To Treat or Not?
A novel use of medical therapy soon after surgery for nonfunctioning pituitary adenomas was up for debate, with strong arguments for and against changing the standard of care.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - May 22, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Gamma Knife Radiosurgery Safe in Early Pituitary Tumor Gamma Knife Radiosurgery Safe in Early Pituitary Tumor
A new study shows no significant difference in endocrinopathies with early vs late treatment of residual recurring nonfunctioning pituitary macroadenomas; longer follow-up is needed, researchers say.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 28, 2017 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

The Saga Of The Irish Giant's Bones Dismays Medical Ethicists
Charles Byrne was about 7 feet 7 inches tall, an 18th century marvel whose height came from a pituitary tumor. He asked for privacy in death, but his skeleton is still on display in a London museum.(Image credit: Wellcome Library, London/Wellcome Images) (Source: NPR Health and Science)
Source: NPR Health and Science - March 13, 2017 Category: Consumer Health News Authors: Nell Greenfieldboyce Source Type: news

Study shows multiple-dose, targeted radiation more effective for treating pituitary tumors
(Houston Methodist) A recent patient study at Houston Methodist Hospital proved that multiple small doses of highly focused radiation therapy is safer and more effective than a single larger dose of radiation at destroying pituitary gland tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 16, 2015 Category: Cancer & Oncology Source Type: news

Like Sue Perkins, I have a non-cancerous tumour
After being diagnosed with a non-cancerous tumour, Helen Spain was told she might never be able to conceive. Here she tells her story (Source: Telegraph Health)
Source: Telegraph Health - September 14, 2015 Category: Consumer Health News Tags: non cancerous tumour ivf ivf treatment pre-emclampsia sue perkins pituitary gland tumour pregnant pituitary tumour Source Type: news

Side population in pituitary tumours
Pituitary adenomas cause significant endocrine and mass-related morbidity. Little is known about the mechanisms that underlie pituitary tumour pathogenesis. Mertens and colleagues searched for a side population (SP) in pituitary tumours which represent cells with high efflux capacity and potentially enriched for tumour stem cells (TSCs). They detected a SP in pituitary tumours and identified TSC-associated characteristics, which adds new elements to the unravelling of pituitary tumour pathogenesis and may lead to the identification of new therapeutic targets. Read the full article at Mertens et al. (2015) Endocrine-Relate...
Source: Society for Endocrinology - July 29, 2015 Category: Endocrinology Source Type: news

Narrowing in on pituitary tumors
(Brigham and Women's Hospital) In a new study published in the Proceedings of the National Academy of Sciences on July 27, investigators from Brigham and Women's Hospital present a new technique that could help surgeons more precisely define the locations of pituitary tumors in near real-time. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 27, 2015 Category: Cancer & Oncology Source Type: news

Narrowing in on Pituitary Tumors
New technique to map hormone levels in near real-time could help surgeons detect and remove tumors with precision. (Source: BWH for Journalists)
Source: BWH for Journalists - July 27, 2015 Category: Research Source Type: news

Narrowing in on Pituitary Tumors
New technique to map hormone levels in near real-time could help surgeons detect and remove tumors with precision. (Source: BWH News)
Source: BWH News - July 27, 2015 Category: Hospital Management Source Type: news

Registration still open for Clinical Update 2015
Register for your place at CU 2015 now. This year’s lectures will cover: CET Lecture: Where do pituitary tumours come from? Ashley Grossman (Oxford) How to help your patients lose weight: Paul Aveyard (Oxford) Practical management of anorexia: Andy Jones (Newcastle) Lifelong management of Turner syndrome: Gerry Conway (London) Disorders of Sex Development (DSD): Faisal Ahmed (Glasgow) Traumatic Brain Injury (TBI): Tony Goldstone (London) Nuclear imaging and therapy: Val Lewington (London) "Excellent overview for trainees and early...
Source: Society for Endocrinology - February 27, 2015 Category: Endocrinology Source Type: news

20-year-old in China looks like a young child due to a pituitary tumour
Zeng Yushan, 19, from Huzhu township in China's Sichuan province, was diagnosed with a tumour on her pituitary gland. She stopped growing at the age of seven and has the appearance of a child. (Source: the Mail online | Health)
Source: the Mail online | Health - February 9, 2015 Category: Consumer Health News Source Type: news

Consultant in endocrinology – Hull Royal Infirmary, Hull, UK
Applications are invited for the post of Consultant in Endocrinology to join a team of eight Consultants in the Department of Diabetes, Endocrinology and Metabolism at Hull Royal Infirmary. This post is for pure clinical endocrinology. The successful applicant will be encouraged to further develop a subspecialty area of interest in Endocrinology within the unit. General Medical on-call and ward duties will be shared with colleagues currently in post. Subspecialty services include: pituitary disease, thyroid disease and thyroid eye disease, reproductive medicine, adrenal and gonadal disease. There are joint clinics with neu...
Source: Society for Endocrinology - July 23, 2014 Category: Endocrinology Source Type: news

Pituitary apoplexy in pregnancy
Rapid growth of pituitary tumours in pregnancy is well documented, although pituitary apoplexy is a rare event in pregnancy. Pituitary apoplexy is a potentially life-threatening event if not recognised early.  Hayes et al. describe a woman who presented with pituitary apoplexy in the second trimester of pregnancy. Their case demonstrates that a multidisciplinary approach involving endocrinologists, obstetricians and neurosurgeons can minimise morbidity and mortality in the pregnant apoplectic patient and that early decompressive surgery is safe in the second trimester and can preserve pituitary function. Read th...
Source: Society for Endocrinology - July 22, 2014 Category: Endocrinology Source Type: news

Grandfather has brain tumour pulled out through his NOSE, saving his sight
Nigel Tinsley, 69, from the West Midlands, had a pituitary tumour which was pressing on the optic nerves, causing him to slowly lose his sight. (Source: the Mail online | Health)
Source: the Mail online | Health - July 18, 2014 Category: Consumer Health News Source Type: news

The social psychology of nerve cells
Cholinergic amacrine cells create a 'personal space' in much the same way that people distance themselves from one another in an elevator, researchers have discovered. In addition, the study shows that this feature is heritable and identifies a genetic contributor to it, pituitary tumor-transforming gene 1. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 26, 2014 Category: Science Source Type: news

Remission of prolactinoma after pregnancy
Prolactinomas are pituitary tumours occuring in women of child-bearing age. Treatment with dopamine agonists reduces both prolactin level and tumour size and is effective in restoring fertility, thereby allowing pregnancy.  Whilst studies  have focussed on the risks of treatment and tumour growth during pregnancy, little is known about the outcome of women with prolactinoma after pregnancy and lactation. Domingue et al conducted a retrospective study to study remission after pregnancy and lactation in women with prolactinoma. The results of their study shows that more than 40% of the women with previous...
Source: Society for Endocrinology - May 20, 2014 Category: Endocrinology Source Type: news

Sca1+ pituitary adenoma cells
The role of tumor stem cells in benign tumors such as pituitary adenomas remains unclear. Donangelo and colleagues investigated whether the cells within pituitary adenomas that spontaneously develop in Rb+/− mice are hierarchically distributed with a subset being responsible for tumor growth. They find that Sca1+ cells derived from benign pituitary tumors exhibit an undifferentiated expression profile and tumor-proliferative advantages, and they propose that these cells could represent putative pituitary tumor stem/progenitor cells. Read the full article at Donangelo et al. (2014) Endocrine-Related Cancer 21 203...
Source: Society for Endocrinology - April 25, 2014 Category: Endocrinology Source Type: news

Academic Endocrinologist – Dartmouth-Hitchcock Clinic, New Hampshire, USA
Dartmouth-Hitchcock Clinic in Lebanon, NH and the Geisel School of Medicine at Dartmouth are searching for a BC/BE fellowship-trained endocrinologist. The ideal candidate is a general endocrinologist experienced in thyroid ultrasound and ultrasound guided fine needle aspiration who is interested in leading a thyroid ultrasound practice, as well as participating in the full complement of the Section’s clinical and educational responsibilities, including inpatient and outpatient consultation, and didactic/clinical supervision of medical students, residents, and fellows. 3-5 years of clinical experience is preferred...
Source: Society for Endocrinology - March 11, 2014 Category: Endocrinology Source Type: news

Academic Endocrinologist - Lebanon, New Hampshire, USA
Dartmouth-Hitchcock Clinic in Lebanon, NH and the Geisel School of Medicine at Dartmouth are searching for a BC/BE fellowship-trained endocrinologist. The ideal candidate is a general endocrinologist experienced in thyroid ultrasound and ultrasound guided fine needle aspiration who is interested in leading a thyroid ultrasound practice, as well as participating in the full complement of the Section’s clinical and educational responsibilities, including inpatient and outpatient consultation, and didactic/clinical supervision of medical students, residents, and fellows. 3-5 years of clinical experience is preferred...
Source: Society for Endocrinology - December 16, 2013 Category: Endocrinology Source Type: news

Curcumin inhibits pituitary tumor cell proliferation, induces apoptosis
This article focuses on a study that investigated using curcumin for an unusual tumor growth in the... (Source: NaturalNews.com)
Source: NaturalNews.com - December 10, 2013 Category: Consumer Health News Source Type: news

Mutated stem cells trigger pituitary tumours in children (Medical Xpress, 7 October 2013)
A UK study published in Cell Stem Cell  investigates the developmental origins of adamantinomatous craniopharyngioma. Full article (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 9, 2013 Category: Endocrinology Source Type: news

UCLA-led team may have found key to cause of Cushing disease
(University of California - Los Angeles Health Sciences) UCLA researchers and their colleagues have found that testicular orphan nuclear receptor 4 (TR4) is overexpressed in pituitary tumors that spark the excess production of adrenocorticotrophic hormone (ACTH). The scientists discovered that by knocking down TR4 in lab mice, they were able to reverse tumor growth and excess ACTH production. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 30, 2013 Category: Global & Universal Source Type: news

Potential therapeutic target discovered for Cushing's disease (Medical News Today, 10 May 2013)
A study in Proceedings of the National Academy of Sciences associates an orphan receptor with tumor growth and ACTH secretion in human and mouse pituitary tumour cells. Full article (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 13, 2013 Category: Endocrinology Source Type: news

Potential Therapeutic Target Discovered For Cushing's Disease
Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder. The protein, called TR4 (testicular orphan nuclear receptor 4), is one of the human body's 48 nuclear receptors, a class of proteins found in cells that are responsible for sensing hormones and, in response, regulating the expression of specific genes... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 10, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Salk scientists find potential therapeutic target for Cushing's disease
(Salk Institute) Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 7, 2013 Category: Biology Source Type: news