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Total 7216 results found since Jan 2013.
Exploring stroke risk and prevention in China: insights from an outlier
Aging (Albany NY). 2021 Jun 4;13(undefined). doi: 10.18632/aging.203096. Online ahead of print.ABSTRACTIn contrast to the declining trend in most regions worldwide, the incidence of stroke is increasing in China and is leading to an alarming burden for the national healthcare system. In this review, we have generated new insights from this outlier, and we aim to provide new information that will help decrease the global stroke burden, especially in China and other regions sharing similar problems with China. First of all, several unsolved aspects fundamentally accounting for this discrepancy were promising, including the s...
Source: Aging - June 4, 2021 Category: Biomedical Science Authors: Xinrou Lin Hongxuan Wang Xiaoming Rong Ruxun Huang Ying Peng Source Type: research
Score for Predicting Active Cancer in Patients with Ischemic Stroke: A Retrospective Study
CONCLUSIONS: We devised a clinical score to predict active cancer in patients with ischemic stroke based on the absence of a history of hyperlipidemia and elevated serum D-dimer and fibrinogen levels. The use of this score may allow for early intervention. Further research is needed to confirm the implementation of this score in clinical settings.PMID:34124248 | PMC:PMC8169246 | DOI:10.1155/2021/5585206
Source: Biomed Res - June 14, 2021 Category: Research Authors: Jiwei Jiang Xiuli Shang Jinming Zhao Meihui Cao Jirui Wang Runzhi Li Yanli Wang Jun Xu Source Type: research
Habitual flavonoid intake and ischemic stroke incidence in the Danish Diet, Cancer, and Health Cohort
ConclusionsThese findings suggest that moderate habitual consumption of healthy flavonoid-rich foods is associated with a lower risk of ischemic stroke and further investigation is therefore warranted.
Source: American Journal of Clinical Nutrition - May 8, 2021 Category: Nutrition Source Type: research
Predicting 10-year stroke mortality: development and validation of a nomogram
AbstractPredicting long-term stroke mortality is a clinically important and unmet need. We aimed to develop and internally validate a 10-year ischaemic stroke mortality prediction score. In this UK cohort study, 10,366 patients with first-ever ischaemic stroke between January 2003 and December 2016 were followed up for a median (interquartile range) of 5.47 (2.96 –9.15) years. A Cox proportional-hazards model was used to predict 10-year post-admission mortality. The predictors associated with 10-year mortality included age, sex, Oxfordshire Community Stroke Project classification, estimated glomerular filtration rate (eG...
Source: Acta Neurologica Belgica - August 18, 2021 Category: Neurology Source Type: research
Post Stroke Hyperglycemia as a marker of Stroke Severity and Prognosis: A cohort study
ConclusionFrom our study we can conclude that diabetes mellitus as a risk factor in cases of stroke leads to increase complications and worsens the outcome in cases of stroke whether hemorrhagic or ischemic.RecommendationsFrom our study we recommended strict control of diabetes mellitus when present in cases of stroke to avoid bad outcome and to prevent complications in these cases.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
Disorder Genes Regulate the Progression of Ischemic Stroke through the NF- < em > κ < /em > B Signaling Pathway
Biomed Res Int. 2021 Oct 27;2021:2464269. doi: 10.1155/2021/2464269. eCollection 2021.ABSTRACTStroke is an acute cerebrovascular disease, including ischemic and hemorrhagic stroke. Stroke is the second leading cause of death after ischemic heart disease, which accounts for 9% of the global death toll. To explore the molecular mechanisms of the effects of the dysregulated factors, in the GEO database, we obtained transcriptome data from 24 h/72 h of mice with ischemic stroke and 24 h/72 h of normal mice. We then performed differential gene analysis, coexpression analysis, enrichment analysis, and regulator prediction bioinf...
Source: Biomed Res - November 8, 2021 Category: Research Authors: Wei Wei Wenqiang Xin Yufeng Tang Zhonglun Chen Yue Heng Mingjun Pu Bufan Yang Jiacai Zuo Jingfeng Duan Source Type: research
Cancer and stroke: What do we know and where do we go?
Cancer is an increasingly recognized cause for ischemic stroke, with recent acknowledgement of cancer-related stroke as an emerging stroke subtype with unique pathophysiologic mechanisms. In addition, cancer-related stroke may differ from stroke in the general population as cancer patients may not receive guideline-recommended stroke care, and the occurrence of stroke may also preclude patients from receiving optimal cancer treatments. Due to the high degree of morbidity and mortality associated with both conditions, understanding the relationship between stroke and cancer is crucial.
Source: Thrombosis Research - September 16, 2022 Category: Hematology Authors: Ronda Lun, Deborah Siegal, Tim Ramsay, Dar Dowlatshahi Source Type: research
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke
CONCLUSION: Increased levels of lactic acid, pyruvate, and TMAO may be related to the pathophysiological changes in the minor ischaemic stroke population. High blood pressure, a lack of physical activity, smoking, and increased TMAO level were the influencing factors for the occurrence of minor ischaemic stroke. The serum metabolite TMAO may be associated with MS occurrence.PMID:36237188 | PMC:PMC9552842 | DOI:10.3389/fendo.2022.952918
Source: Cancer Control - October 14, 2022 Category: Cancer & Oncology Authors: Chen Chen Xiaoyuan Qiao Jianyong Guo Ting Yang Min Wang Yipeng Ma Shuhe Zhao Ling Ding Hong Liu Jintao Wang Source Type: research
Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes
This study suggests that endothelial-specific ATX leads to increased LPA in the brain vasculature following ischemic-reperfusion and ultimately disrupts vascular permeability, resulting in adverse stroke outcomes.PMID:36766854 | DOI:10.3390/cells12030511
Source: Atherosclerosis - February 11, 2023 Category: Cardiology Authors: Susmita Bhattarai Utsab Subedi Shrivats Manikandan Sudha Sharma Papori Sharma Chloe Miller Md Shenuarin Bhuiyan Srivatsan Kidambi Vassilis Aidinis Hong Sun Sumitra Miriyala Manikandan Panchatcharam Source Type: research
The interaction between intestinal microenvironment and stroke
CONCLUSION: The structure and function of the intestinal environment can influence neurological function and cerebral ischemic outcome. Improving the intestinal microenvironment by targeting the gut microbiota may be a new direction in treating stroke.PMID:37309254 | DOI:10.1111/cns.14275
Source: CNS Neuroscience and Therapeutics - June 13, 2023 Category: Neuroscience Authors: Linna Zhao Jie Xiao Songlin Li Yuying Guo Rong Fu Shengyu Hua Yuzheng Du Shixin Xu Source Type: research
