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Total 7216 results found since Jan 2013.

A Phase IIB Clinical Trial of Normobaric Oxygen Therapy (NBO) in Acute Ischemic Stroke (AIS) (S02.001)
CONCLUSIONS: NBO did not affect NIHSS or infarct growth in this trial. The observed imbalance in deaths remains unexplained, but appears unrelated to NBO. Further studies are warranted.Supported by: NIH-NINDS.Disclosure: Dr. Singhal has received personal compensation as an expert witness in medicolegal cases involving stroke in young adults. Dr. Singhal's wife is an employee of Vertex Pharmaceuticals, Inc. Dr. Singhal has received research support from Pfizer and Photothera, Inc. Dr. On Behalf of Partners SPOTRIAS Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Singhal, A., on Behalf of Partners SPOTRIAS Investigators, Tags: S02 Acute Stroke Therapy Source Type: research

The Activity of Malignancy May Determine Stroke Pattern in Cancer Patients
It has been suggested that stroke in patients with cancer may differ from the conventional pattern. The aim of this study was to evaluate the burden of vascular risk factors, stroke etiology, and short-term outcome in patients with active and nonactive malignancy compared with patients without cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - February 7, 2015 Category: Neurology Authors: Anna G. Karlińska, Grażyna Gromadzka, Michał A. Karliński, Anna Członkowska Source Type: research

Frequency of New Pulmonary Neoplasm Incidentally Detected by Computed Tomography Angiography in Acute Stroke Patients—A Single-Center Study
Incidental findings of suspect lung opacities are common in computed tomography (CT)–based thorax examinations, especially in high-risk patients, such as stroke patients. Screening with CT of the thorax has detected lung cancer in approximately .31%-1.20% of high-risk populations. The aim of the present study was to report the frequency of suspect lung opacities on routine acute stroke imaging.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2015 Category: Neurology Authors: Line Bentsen, Anders Christensen, Inger Havsteen, Hanne Hansen, Christian Ovesen, Hanne Christensen Source Type: research

Voxel-Based Lesion Mapping of Cryptogenic Stroke in Patients with Advanced Cancer: A Detailed Magnetic Resonance Imaging Analysis of Distribution Pattern
Ischemic stroke is one form of cancer-associated thrombosis that can greatly worsen a patient's performance status. The present investigation aimed to elucidate the characteristic distribution pattern(s) of cryptogenic stroke lesions using a voxel-based lesion-mapping technique and examine the differences in clinical manifestations between cryptogenic and conventional strokes in patients with advanced cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2017 Category: Neurology Authors: Takamune Achiha, Masatoshi Takagaki, Hiroshi Oe, Mio Sakai, Hitoshi Matsui, Katsuhiko Nakanishi, Tomohiko Ozaki, Yasunori Fujimoto, Toshiki Yoshimine, Katsuyuki Nakanishi, Manabu Kinoshita Source Type: research

Is the Intensity or Duration of Treadmill Training Important for Stroke Patients? A Meta-Analysis
Stroke, the third highest cause of death after cancer and cardiac diseases, is a strong cause of adult disability in most countries. Therefore, the aim of the current meta-analysis was to examine the most effective intensity and duration of treadmill training on motor performance in stroke subjects.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2017 Category: Neurology Authors: Sadegh Abbasian, Mahsa Rastegar MM Tags: Review Article Source Type: research

Do Reduced Copayments Affect Mortality after Surgery due to Stroke? An Interrupted Time Series Analysis of a National Cohort Sampled in 2003-2012
The South Korean government introduced a policy in 2 phases, in September 2005 and in January 2010, for reducing copayments for patients with critical diseases, including stroke, to prevent excessive medical expenditures and to ease economic barriers. Previous studies of the effect of this policy were focused primarily on cancer. Therefore, we investigated the relationship between this policy and 1-year mortality after surgery among patients with stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2018 Category: Neurology Authors: Kyu-Tae Han, Seung Ju Kim, Sun Jung Kim, Ji Won Yoo, Eun-Cheol Park Source Type: research

Antithrombotic Therapy Strategy for Cancer-Associated Ischemic Stroke: A Case Series of 26 Patients
The risk of complications from thromboembolism is increased for patients with malignancy. Cancer-associated stroke is also a serious issue with regard to the management of patients with cancer because stroke incidence often causes disabilities that affect daily life and cancer treatment strategy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2018 Category: Neurology Authors: Hiroyuki Naito, Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Hiroki Ueno, Kazuhide Ochi, Hirofumi Maruyama Tags: Case Studies Source Type: research

Effects of l-Carnitine Supplementation, Botulinum Neurotoxin Injection, and Rehabilitation for a Chronic Stroke Patient
Botulinum neurotoxin injection therapy and rehabilitation have been conducted for stroke patients to reduce the spasticity of their affected limbs and improve their walking ability and daily living. Furthermore, their disability was reported to be related to muscle wasting. Supplementation of l-carnitine was reported to improve physical endurance and was used to treat sarcopenia in, for example, patients with cancer. Here, we report a case of chronic stroke with muscle wasting in a patient with improved walking endurance by l-carnitine supplementation, botulinum neurotoxin injection, and rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2018 Category: Neurology Authors: Satoshi Endo, Tadashi Takahashi, Masaya Sato, Yoshinori Noya, Masayoshi Obana Source Type: research

Temporal Trends in the Use of Acute Recanalization Therapies for Ischemic Stroke in Patients with Cancer
Objective: We sought to characterize the US nationwide temporal trends in recanalization therapy utilization for ischemic stroke among patients with and without cancer. Methods: We identified all acute ischemic stroke (AIS) hospitalizations in the National Inpatient Sample from January 1, 1998 to September 30, 2015. The primary exposure was solid or hematologic cancer. The primary outcome was use of intravenous thrombolysis. The secondary outcome was use of endovascular therapy (EVT). Results: Among 9,508,804 AIS hospitalizations, 503,510 (5.3%) involved cancer patients.
Source: Journal of Stroke and Cerebrovascular Diseases - May 28, 2019 Category: Neurology Authors: Abhinaba Chatterjee, Alexander E. Merkler, Santosh B. Murthy, Jaclyn E. Burch, Monica L. Chen, Gino Gialdini, Hooman Kamel, Karla V. Ballman, Babak B. Navi Source Type: research

Early Prediction of One-Year Mortality in Ischemic and Haemorrhagic Stroke
The worldwide stroke incidence is 17 million per year,1 and 12 % of all deaths worldwide are caused by stroke making it the third leading cause of death after cancer and ischemic heart disease.2
Source: Journal of Stroke and Cerebrovascular Diseases - February 6, 2020 Category: Neurology Authors: Jacob Liljehult, Thomas Christensen, Karl Bang Christensen Source Type: research

Low Serum Eicosapentaenoic Acid Levels in Cryptogenic Stroke with Active Cancer
Since Armand Trousseau first described migratory superficial thrombophlebitis in 1865, patients with malignant cancer have been known to be in a hypercoagulable state and at risk for the development of cancer-associated thrombosis.1 Approximately 7% of cancer patients have symptomatic cerebrovascular diseases during the clinical course of cancer, and 15% have cerebrovascular lesions at autopsy.2 Previous studies have demonstrated that cancer patients with cryptogenic ischemic stroke often have high serum D-dimer levels and multiple vascular lesions and show cryptogenic stroke etiology, which seems to be due to a hypercoagulable state.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2020 Category: Neurology Authors: Tesseki Izumi, Hitoki Nanaura, Naohiko Iguchi, Maki Ozaki, Kazuma Sugie Source Type: research

Occult lung cancer manifesting within the first year after stroke
Lung cancer and stroke share smoking as a major cause of disease. We investigated prevalence and risk of occult lung cancer with manifestation during the first year after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Alejandro Daniel Babore, Anne Julie Tybjerg, Klaus Kaae Andersen, Tom Skyhoj Olsen Source Type: research

D-dimer and Body CT to Identify Occult Malignancy in Acute Ischemic Stroke
Patients with acute ischemic stroke associated with cancer have D-dimer elevations greater than those with acute ischemic stroke or cancer alone. While D-dimer has been proposed as a screening tool to identify such patients, its use in clinical practice to identify malignancy and to inform the use of CT scanning has not been well characterized.
Source: Journal of Stroke and Cerebrovascular Diseases - October 8, 2020 Category: Neurology Authors: Jon Rosenberg, David Do, Brett Cucchiara, Steven R. Mess é Source Type: research

Reperfusion Therapy in Acute Ischemic Stroke with Active Cancer: A Meta-Analysis Aided by Machine Learning
While the prevalence of active cancer patients experiencing acute stroke is increasing, the effects of active cancer on reperfusion therapy outcomes are inconclusive. Thus, we aimed to compare the safety and outcomes of reperfusion therapy in acute stroke patients with and without active cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - March 26, 2021 Category: Neurology Authors: Mi-Yeon Eun, Eun-Tae Jeon, Kwon-Duk Seo, Dongwhane Lee, Jin-Man Jung Source Type: research